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Genetic Determinants Of Diabetes

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In this documentary shortproduced and directed by Katie Doyle with partial support from the AADE Education and Research Foundationwe follow the story of Diabetes Educator, Tatiana, as she works with Hema, to manage Hema's diabetes and provide culturally competent care.

Impact Of Common Genetic Determinants Of Hemoglobin A1c On Type 2 Diabetes Risk And Diagnosis In 1 Ancestrally Diverse Populations: A Transethnic Genome-wide Meta-analysis

Impact of Common Genetic Determinants of Hemoglobin A1c on Type 2 Diabetes Risk and Diagnosis in 1 Ancestrally Diverse Populations: A Transethnic Genome-Wide Meta-Analysis Wong, A; (2017) Impact of Common Genetic Determinants of Hemoglobin A1c on Type 2 Diabetes Risk and Diagnosis in 1 Ancestrally Diverse Populations: A Transethnic Genome-Wide Meta-Analysis. PLoS Medicine 10.1371/journal.pmed.1002383 . BACKGROUND: Glycated hemoglobin (HbA1c) is used to diagnose type 2 diabetes (T2D) and assess glycemic control in patients with diabetes. Previous genome-wide association studies (GWAS) have identified 18 HbA1c-associated genetic variants. These variants proved to be classifiable by their likely biological action as erythrocytic (also associated with erythrocyte traits) or glycemic (associated with other glucose-related traits). In this study, we tested the hypotheses that, in a very large scale GWAS, we would identify more genetic variants associated with HbA1c and that HbA1c variants implicated in erythrocytic biology would affect the diagnostic accuracy of HbA1c. We therefore expanded the number of HbA1c-associated loci and tested the effect of genetic risk-scores comprised of ery Continue reading >>

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  1. charlena

    Boardsort.com

    has anyone figured out how to clean those?
    the contain a bit of pgm for the size ...seems it would be worth it?

  2. POG

    This is a good question. I have boxes of out of date test strips that haven't been used.

  3. charlena

    I was trying to respond to a message i got about this post but i couldn't load the photo so ill try here....
    I have tried acetone, bleach, goof off, alcohol, soap and nothing takes the goopy glue that holds the two sides together. that would need removed before trying too extract the traces from the other side...see photo

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Insulin Dependent Diabetes|Insulin Dependent Diabetes Mellitus (Type I) http://bit.ly/2pTU1O8 Insulin Dependent Diabetes mellitus (IDDM), also known as type 1 diabetes, usually begins before age 15, but can also occur in adults. Diabetes includes the pancreatic gland, which is located behind the stomach (Figure 1). Special cells (beta cells) in the pancreas produce a hormone called insulin. The body is made up of millions of cells. All cells need glucose (sugar) from the food we eat for energy. Just as a car can not run without gas, the body can not function without glucose. Insulin is the "key" that allows glucose to enter cells. Without this key, glucose remains in the bloodstream and cells can not use it for energy. Instead, glucose builds up in the blood and spills into the urine. When a person develops type 1 diabetes, the pancreas stops producing insulin. To help the body's cells use glucose, a child with type 1 diabetes mellitus (DM) should receive insulin by injection (injection).http://bit.ly/2pTU1O8 What happens in type 1 diabetes The cause of diabetes is not known. Some experts believe that diabetes is inherited (it works in families), but genetics is not clearly underst

Dr Raymond Noordam, Genetic Determinants For Insulin-dependent Type 2 Diabetes Mellitus

Dr Raymond Noordam, Genetic determinants for insulin-dependent type 2 diabetes mellitus Dr Raymond Noordam, Genetic determinants for insulin-dependent type 2 diabetes mellitus Principal Investigator: Dr Raymond Noordam Tags: 22474 , diabetes , genetics , insulin-depedent 1a: Type 2 diabetes mellitus (T2D) is a heterogeneous disease caused by different mechanisms, including insulin resistance and pancreatic malfunction. Of the patients diagnosed with T2D, a fair amount of the patients requires insulin analogs shortly (e.g., within 1 year) after diagnoses, which is indicative of a major role for pancreatic malfunction already at the moment of diagnosis. Malfunction of the pancreas results in an insulin-dependent T2D phenotype. In this project, we will investigate genetic determinants for insulin-dependent type 2 diabetes mellitus as defined by the use of insulin analogs within 1 year after diagnosis. 1b: The prevalence and incidence of type 2 diabetes mellitus is increasing. After diagnosis, patients with type 2 diabetes are often prescribed oral glucose-lowering drugs, but treatment response is often insufficient or associated with serious adverse drug reactions. A better understan Continue reading >>

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  1. joezoey

    AIC 5.7 do i need to be concerned

    I just was operated for open heart surgery and my blood work came back with a blood level of 90 and my a1c wqas 5.7. I would like some input on this issue

  2. gr8finds

    According to NIH, an A1C of 5.7 indicates prediabetes. https://www.niddk.nih.gov/health-information/...

  3. Bun10

    My A1C is 5.7 and my doctor is on my case all the time. She has me convinced that if I reach 6.0 I will explode or implode or see angels playing harps. Her team says the "normal" non diabetic is about 4.5 I was diagnosed two years ago. Last month she finally let me sit in with the nutritionist who sees her diabetic patients. She was surprised I wanted to go to it. The other patients thought my 5.7 was wonderful. But I 'm thinking it isn't. its more like 900 lb people being envious of 400 lb people. I hoped to learn from the long time diabetics at my Doctors nutrionist/diabetic meeting but they offered nothing and had never heard of Dreamfield pasta which the nutritionist said was wonderful and she was glad I brought it up because she isn't allowed to mention brands. I subscribe to diabetic living. Couldn't have made it two years without them. They were my only source of 'what can I eat and why'. I read and reread every magazine over and over. Finding diabetic support in my town seems impossible. Good thing i love veggies and salads.

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What is GENETIC ENGINEERING? What does GENETIC ENGINEERING mean? GENETIC ENGINEERING meaning - GENETIC ENGINEERING definition - GENETIC ENGINEERING explanation. Source: Wikipedia.org article, adapted under https://creativecommons.org/licenses/... license. Genetic engineering, also called genetic modification, is the direct manipulation of an organism's genome using biotechnology. It is a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms. New DNA may be inserted in the host genome by first isolating and copying the genetic material of interest using molecular cloning methods to generate a DNA sequence, or by synthesizing the DNA, and then inserting this construct into the host organism. Genes may be removed, or "knocked out", using a nuclease. Gene targeting is a different technique that uses homologous recombination to change an endogenous gene, and can be used to delete a gene, remove exons, add a gene, or introduce point mutations. An organism that is generated through genetic engineering is considered to be a genetically modified organism (GMO). The first GMO

Genetic Determinants Of Albuminuria And Renal Disease In Diabetes Mellitus

Genetic determinants of albuminuria and renal disease in diabetes mellitus Correspondence and offprint requests to: Barry I. Freedman, MD, Department of Internal Medicine, Section on Nephrology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1053, USA. Email: [email protected] Search for other works by this author on: Nephrology Dialysis Transplantation, Volume 21, Issue 1, 1 January 2006, Pages 1316, Michle M. Sale, Barry I. Freedman; Genetic determinants of albuminuria and renal disease in diabetes mellitus, Nephrology Dialysis Transplantation, Volume 21, Issue 1, 1 January 2006, Pages 1316, albuminuria , chronic kidney failure , diabetes mellitus , genetics Type 2 diabetes mellitus (T2DM) is increasing in epidemic proportions. The worldwide prevalence of diabetes was estimated to be 171 million cases in 2000 and is projected to rise to 366 million cases by 2030 [ 1 ]. Given current trends, the lifetime risk for developing T2DM is 30% in European Americans born in 2000, contrasted with 40% in African American males and 49% in African American females [ 2 ]. This global epidemic will clearly increase the development of diabetic neph Continue reading >>

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  1. katerina_98

    Class B Diabetes

    I recently read a report where a physician listed a diagnosis of Class B Diabetes? Anyone heard of this and is this even used anymore?
    Thank you,

  2. Sarah_Stevens

    http://en.wikipedia.org/wiki/Diabete..._and_pregnancy
    I had to look this up the other day since my doctors were doing DMA1

  3. preserene

    Classification of diabetes:
    The White classification, named after Priscilla White who pioneered research on the effect of diabetes types on perinatal outcome, is widely used to assess maternal and fetal risk. It distinguishes between gestational diabetes (type A) and diabetes that existed before pregnancy (pregestational diabetes). These two groups are further subdivided according to their associated risks and management.
    There are 2 classes of gestational diabetes (diabetes which began during pregnancy):
    Class A1: gestational diabetes; diet controlled
    Class A2: gestational diabetes; insulin controlled
    The second group of diabetes which existed before pregnancy can be split up into these classes:
    Class B: onset at age 20 or older or with duration of less than 10 years
    Class C: onset at age 10-19 or duration of 10–19 years
    Class D: onset before age 10 or duration greater than 20 years
    Class E: overt diabetes mellitus with calcified pelvic vessels
    Class F: diabetic nephropathy
    Class R: proliferative retinopathy
    Class RF: retinopathy and nephropathy
    Class H: ischemic heart disease
    Class T: prior kidney transplant
    An early age of onset or long-standing disease comes with greater risks, hence the first three subtypes

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