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Environmental Determinants Of Diabetes

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The Environmental Determinants Of Diabetes In The Young (teddy) Study.

Ann N Y Acad Sci. 2008 Dec;1150:1-13. doi: 10.1196/annals.1447.062. The Environmental Determinants of Diabetes in the Young (TEDDY) Study. Rewers M , Barriga K , Baxter J , Eisenbarth G , Gesualdo P , Hoffman M , Ide L , Norris J , Waugh K , Simell OG , Nanto-Salonen K , Ilonen J , Knip M , Veijola R , Simell T , Hyty H , Virtanen SM , Kronberg-Kippil C , Torma M , Simmell B , Ruohonen E , Romo M , Mantymaki E , Niininen T , Nyblom M , Stenius A , Lernmark A , Agardh D , Almgren P , Andersson-Turpeinen M , Andrn-Aronsson C , Ask M , Carlsson UM , Cilio C , Bremer J , Ericson-Hallstrm E , Gerardsson J , Gustavsson B , Hansson G , Hansson I , Hansen M , Hyberg S , Hkansson R , Ivarsson S , Johansoon J , Larsson H , Lernmark B , Markan M , Melin J , Mnsson-Martinez M , Nilsson A , Rahmati K , Jrvirova MS , Sjberg B , Trn C , Wallin A , Wigheden I , Wimar A , Hagopian WA , Hui P , Brantley M , Crouch CC , Hay KM , Ayres S , Hammar C , Steptikova V , Skidmore J , Bang B , Mulenga D , Vanneman N , Ewing J , Whitaker I , Wion E , Arrecis E , Trope L , Becker D , Franciscus M , Dalmagro-Elias M , Daftary A , Krischer JP , Abbondondolo M , Ballard L , Bounmananh L , Brown R , Cuthbertson D Continue reading >>

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Popular Questions

  1. righteousdude2

    When is Best Time to Take Metformin ???

    My Endo told me he didn't care if I took Metformin prior to, or, following my meals (500Mg). He said to experiment, and as of today, I have yet to find out which way is most beneficial. Also, if I take before dinner, do I take them a set amount of minutes prior to the meal, or, along with the meal. This would also apply to after a meal, Do I wait a set amount of time, or, gobble down the Metformin right after my last bite of tasty morsels of food??
    Your experience would be helpful, as my doctors, and the pharmacy have no real, hard-and-fast rules as to what is the best time to take Metformin.
    Thanks for any of your wisdom and insight. I'd really like to get the most benefits out of this pill.
    Shalom,
    Pastor Paul

  2. onaughmae

    Quote:

    Originally Posted by righteousdude2
    My Endo told me he didn't care if I took Metformin prior to, or, following my meals (500Mg). He said to experiment, and as of today, I have yet to find out which way is most beneficial. Also, if I take before dinner, do I take them a set amount of minutes prior to the meal, or, along with the meal. This would also apply to after a meal, Do I wait a set amount of time, or, gobble down the Metformin right after my last bite of tasty morsels of food??
    Your experience would be helpful, as my doctors, and the pharmacy have no real, hard-and-fast rules as to what is the best time to take Metformin.
    Thanks for any of your wisdom and insight. I'd really like to get the most benefits out of this pill.
    Shalom,
    Pastor Paul
    I take mine in the morning and night...approximately 12 hours apart. I dont think it really matters if it is at a meal or not since it is not a pancreas stimulating drug. The only thing I can think of is that metformin can cause GI upset so maybe taking it with a meal would help. I have been taking it so long now I dont have the GI issues so I take it just whenever.

  3. Shanny

    The reason nobody has any hard fast rules is because the same rule doesn't work for everyone. You actually DO have to puzzle out what works best for you. The only reason that I know of for taking with food, is if it causes you gastric distress. If you get side effects, then take it with food. If not, then it wouldn't matter if you take it with food or not. I have no ill effects with it, so I take a couple of my doses on an empty stomach, but the midday dose goes down with a meal, since the timing happens to coincide.
    Other reasons for certain times would be simply so you don't forget to take it. If it helps you remember to take it when it's mealtime, by all means take it at mealtime. But if you have a handful of pills that you already take in the morning or night on an empty stomach, take it with those (assuming you aren't getting gastric side effects, of course).
    If you're taking it with meals, it really doesn't matter if it's before or after - and timing it down to the minute is splitting hairs. The idea is to get it into your stomach & mushed around with all the food so if it DOES cause distress, that effect is blunted - same as with many antibiotics which are prescribed to take with food, since they can upset your stomach. If you'd rather enjoy the lasting flavors of your final bite of food instead of flushing it away taking a pill - for gosh sake take it BEFORE the meal. The only other consideration, and I personally have not experienced this, but some people say extra fatty meals cause them trouble with met.
    Metformin doesn't work like insulin or even aspirin; it builds up in your body over a period of days/weeks, and all you're doing now is maintaining that blood level. As long as you're taking it about the same time every day, you should be fine.

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