Metformin Weight Loss – Does It Work?
Metformin weight loss claims are something that are often talked about by health professionals to be one of the benefits of commencing metformin therapy, but are they true? At myheart.net we’ve helped millions of people through our articles and answers. Now our authors are keeping readers up to date with cutting edge heart disease information through twitter. Follow Dr Ahmed on Twitter @MustafaAhmedMD Metformin is possibly one of the most important treatments in Type II Diabetes, so the question of metformin weight loss is of the utmost importance, as if true it could provide a means to lose weight as well as control high sugar levels found in diabetes. What is Metformin? Metformin is an oral hypoglycemic medication – meaning it reduces levels of sugar, or more specifically glucose in the blood. It is so effective that the American Diabetes Association says that unless there is a strong reason not to, metformin should be commenced at the onset of Type II Diabetes. Metformin comes in tablet form and the dose is gradually increased until the maximum dose required is achieved. How Does Metformin Work & Why Would it Cause Weight Loss? Metformin works by three major mechanisms – each of which could explain the “metformin weight loss” claims. These are: Decrease sugar production by the liver – the liver can actually make sugars from other substances, but metformin inhibits an enzyme in the pathway resulting in less sugar being released into the blood. Increase in the amount of sugar utilization in the muscles and the liver – Given that the muscles are a major “sink” for excess sugar, by driving sugar into them metformin is able to reduce the amount of sugar in the blood. Preventing the breakdown of fats (lipolysis) – this in turn reduces the amount of fatt Continue reading >>
Metformin (glucophage) And Weight Loss
Tweet Metformin, a generic diabetes treatment usually sold under the brand name Glucophage, may help people with diabetes to lose weight by lowering their appetites. Insulin makes people overweight by acting on the brain to cause hunger, making the liver manufacture fat and fill fat cells in the stomach. Avoiding obesity is a matter of avoiding foods high in blood sugar, and taking medication that prevents blood sugar levels from climbing too high. Glucophage function The function of diabetes drug Glucophage is to reduce the release levels of sugar from your liver. This stops blood glucose levels from rising too high, and means that the body does not have to produce as much insulin. Therefore, the patient is not as hungry. Type 2 diabetes drug Metformin (Glucophage) may be used successfully as a medication for type 2 diabetes. Lowers insulin levels It lowers insulin levels, helps to prevent diabetes complications, and helps people with diabetes to lose weight. Losing weight whilst taking Metformin (Glucophage) means also eating a healthy diet. Eating lots of foods that boost blood sugar levels will counteract the effects of Metformin. Most doctors prescribe 500mg of Metformin (Glucophage) before eating. Tweet Type 2 diabetes mellitus is a metabolic disorder that results in hyperglycemia (high blood glucose levels) due to the body: Being ineffective at using the insulin it has produced; also known as insulin resistance and/or Being unable to produce enough insulin Type 2 diabetes is characterised by the body being unable to metabolise glucose (a simple sugar). This leads to high levels of blood glucose which over time may damage the organs of the body. From this, it can be understood that for someone with diabetes something that is food for ordinary people can become a s Continue reading >>
Pcos Weight Gain Causes And Treatments
Many of these conditions can lead to heart disease . In fact, women with PCOS are four to seven times more likely to have a heart attack than women of the same age without the condition. Experts think weight gain also helps trigger PCOS symptoms, such as menstrual abnormalities and acne . What can I do to lose weight if I have polycystic ovary syndrome? Losing weight not only cuts your risk for many diseases, it can also make you feel better.When you have PCOS, shedding just 10% of your body weight can bring your periods back to normal. It can also help relieve some of the symptoms of polycystic ovary syndrome. Weight loss can improve insulin sensitivity. That will reduce your risk of diabetes , heart disease, and other PCOS complications. To lose weight, start with a visit to your doctor. The doctor will weigh you and check your waist size and body mass index. Body mass index is also called BMI, and it is the ratio of your height to your weight. Your doctor may also prescribe medication. Several medications are approved for PCOS, including birth control pills and anti-androgen medications. The anti-androgen medications block the effects of male hormones. A few medications are used specifically to promote weight loss in women with PCOS. These include: Metformin ( Glucophage ). Metformin is a diabetes drug that helps the body use insulin more efficiently. It also reduces testosterone production. Some research has found that it can help obese women with PCOS lose weight. Thiazolidinediones. These should be used with contraception . The drugs pioglitazone ( Actos ) and rosiglitazone ( Avandia ) also help the body use insulin. In studies, these drugs improved insulin resistance. But their effect on body weight is unclear. All patients using Avandia must review and fully un Continue reading >>
Weight Loss Or Gain On Metformin?
Metformin is a drug primarily prescribed to patients with Type 2 diabetes to help control blood sugar. This drug has been studied to determine its safety and effectiveness for weight loss in nondiabetic patients. Doctors have prescribed metformin for a variety of alternative uses; talk to your doctor to determine whether this medication is right for you. Video of the Day Metformin controls the amount of sugar, also known as glucose, in your blood, by decreasing the amount of glucose your liver makes and reducing the amount of glucose your body absorbs from the foods you eat. Additionally, metformin improves how the body responds to insulin, the body's natural control factor for glucose regulation in the bloodstream. Side Effects of Metformin Metformin has minimal adverse side effects when taken as directed. The most common is gastrointestinal upset that may lead to nausea, diarrhea and vomiting. Some patients also experience side effects similar to hypoglycemia, which should be discussed with a doctor immediately. Patients on metformin often experience the added benefit of weight maintenance or weight loss. This side effect can be attributed to the primary function of this drug, which is to help the body monitor blood glucose and insulin levels, two factors that play a significant role in weight management. Metformin for Weight Loss Currently, doctors are not prescribing metformin to patients who are simply looking to lose weight. Aside from the discomfort of the initial side effects, metformin is only safe and effective for individuals who are overweight or obese and suffering from impaired insulin secretion. A 2001 study by the New York Medical College found that nondiabetic women who gained weight midlife and had excess insulin benefited from a daily dose of metformi Continue reading >>
Does Metformin Cause Weight Loss? What To Know Before You Take It
If you’re managing type 2 diabetes with metformin (Glucophage), you might be well acquainted with unwanted side effects of this drug — namely, upset stomach, diarrhea, muscle aches, and sleepiness. These can be a figurative and literal pain, but you might welcome one side effect of metformin with open arms, particularly if you’ve struggled to lose weight. Metformin isn’t a weight loss drug, but researchers have found a link between the drug and weight loss. In fact, a long-term study published in April 2012 in the journal Diabetes Care that was conducted by the Diabetes Prevention Program (DPP) concluded that the drug could serve as a treatment for excess body weight, although more studies are needed. What Is Metformin and How Does It Work? “[Metformin] has been considered a first-line medication in the treatment of type 2 diabetes, and it mainly acts by lowering the amount of glucose released by the liver,” says Minisha Sood, MD, an endocrinologist at Lenox Hill Hospital in New York City. “It also helps a hormone called insulin to work better by helping muscles use glucose in a more efficient manner. When insulin works better (and insulin sensitivity improves), a person’s insulin levels are lower than they would be otherwise.” There’s no cure for type 2 diabetes, but the right combination of medication and healthy lifestyle can stabilize blood sugar levels, which, of course, is the end goal of any diabetes treatment. As the medication helps your body properly metabolize food and restores your ability to respond to insulin, you’ll not only feel better, you can potentially avoid complications of high blood sugar, such as heart disease, kidney damage, nerve damage (diabetic neuropathy), and eye damage (retinopathy). Why Does Metformin Cause Weight Lo Continue reading >>
Is It Possible To Stop Weight Gain From Metformin? If Yes, Then How?
Metformin is a medication that treats the symptoms of type 2 diabetes. Dont stop taking metformin without talking to your doctor first. You may be able to safely stop taking metformin if your blood sugar is under control. Metformin (Glumetza, Riomet, Glucophage, Fortamet) is the most common medication people use to treat diabetes worldwide. It can help control high blood sugar in people with type 2 diabetes. Its usually available as either small, white tablets or clear liquid. In both cases, you take it orally, or by the mouth, before meals multiple times per day. Metformin doesnt treat the underlying causes of diabetes. Instead, it treats the symptoms of diabetes by lowering blood sugar and increasing the use of glucose in peripheral muscles and the liver. Metformin does several good things in addition to improving blood sugar: It lowers lipids, resulting in a decrease in blood triglyceride levels. It slightly decreases your bad cholesterol, or low-density lipoprotein (LDL). It slightly increases the good cholesterol, or high-density lipoprotein (HDL). Stopping metformin removes the benefits it provides, namely lower blood sugar. It may be possible to stop taking medication for the treatment of type 2 diabetes if you make certain lifestyle changes, such as losing weight and getting more exercise. You should only stop taking metformin under the care of your doctor to avoid the risk of high blood glucose levels. In some cases, metformin leads to poor absorption of vitamin B-12. That can lead to a vitamin B-12 deficiency. Taking metformin doesnt lead to weight gain. However, it might lead to a small amount of weight loss. Hypoglycemia, or low blood sugar, might occur since metformin lowers blood sugar. Its important to monitor your blood sugar regularly and adjust your d Continue reading >>
Can Metformin Help With Weight Loss?
Metformin is a drug prescribed to manage blood sugar levels in people with type 2 diabetes. You may have heard that metformin can also help you lose weight. But is it true? The answer is a resounding maybe. Here’s what you should know about what metformin can do for weight loss, as well as why your doctor may prescribe it for you. According to research, metformin can help some people lose weight. However, it’s not clear why metformin may cause weight loss. One theory is that it may prompt you to eat less by reducing your appetite. It may also change the way your body uses and stores fat. Although studies have shown that metformin may help with weight loss, the drug is not a quick-fix solution. According to one long-term study, the weight loss from metformin tends to occur gradually over one to two years. The amount of weight lost also varies from person to person. In the study, the average amount of weight lost after two or more years was four to seven pounds. Taking the drug without following other healthy habits may not lead to weight loss. Individuals who follow a healthy diet and exercise while taking metformin tend to lose the most weight. This may be because metformin is thought to boost how many calories you burn during exercise. If you don’t exercise, you likely won’t have this benefit. In addition, any weight loss you have may only last as long as you take the medication. That means if you stop taking metformin, there’s a good chance you will return to your original weight. And even while you’re still taking the drug, you may slowly gain back any weight you’ve lost. In other words, metformin may not be the magic diet pill some people have been waiting for. It has been shown to reduce weight in some, but not others. One of the benefits of metformin Continue reading >>
'can I Take Metformin If I Want To Lose Weight?'
'Can I Take Metformin If I Want To Lose Weight?' Some doctors are now prescribing this diabetes drug for weight loss. But is it safe? Metformin is a drug designed to treat patients with Type 2 diabetes, but it comes with an interesting side effect: weight loss . And Reddit is filled with stories from people who have lost weight on the drug. Was trying to lose weight for a long time with no success, one person wrote of being prescribed metformin. Im on 1000 mg a day and am down 10 pounds. I saw weight loss at first with 500 mg twice per day, another wrote. The difference was almost immediate. While some people say the drug didnt do much for them, others swear by iteven those that dont have Type 2 diabetes, saysFatima Cody Stanford, M.D., an instructor of medicine and pediatrics at Harvard Medical School and obesity medicine physician at Massachusetts General Hospital. In fact, Cody Stanford says that she often prescribes the medication to overweight or obese people who don't have Type 2 diabetes. Heres what you need to know about the drug. (Hit the reset buttonand burn fat like crazy with The Body Clock Diet !) Metformin causes a decrease in the release of glucose from a persons liver. This helps to lower a persons blood sugar when its too high and restore the way someone uses food to make energy, according to the Mayo Clinic . " Weight loss can occur because it decreases appetite in some people who take it," says women's health expert Jennifer Wider , M.D. In order for the prescription to work effectively, the amount of metformin you take must be balanced against your diet and exercise because it helps level out your blood sugar, the clinic says. For that reason, if you change your diet or exercise, you doctor may need to change the amount of metformin you take. Check Continue reading >>
Why Am I Gaining Weight Still? Does Metformin Cause Weight Gain????
Why am I gaining weight still? Does Metformin cause weight gain???? Registration is fast, simple and absolutely free so please,join our community todayto contribute and support the site. This topic is now archived and is closed to further replies. Why am I gaining weight still? Does Metformin cause weight gain???? Since i've been so diligent with eating and been taking Metformin for about 3 weeks now. Though I am only taking 3/4 (going to 500 mgs in another day or two) of a 500 mg pill and my blood sugar numbers have been even in the 80's and very little fast foods, I was blown away when I stepped on the scale this a.m. I thought low carb helped you to lose weight and i've been doing really good at it and doing cardio, running even, on my treadmill and it felt good!. Have not been using any weights yet so it isnt muscle, I wish...I'm just really bummed to see the scale going up or at least if it was the same I would of been happy but nooooooooo... I've been active more in the house too, finding projects to do instead of sitting on my butt.. I dont know happened...can someone tell me what i'm doing wrong please.. I thought lower blood sugar numbers meant losing weight. I've not had a BS in a week over 109 and my a.m. fastings have been 93 to 100 everyday and since I stopped taking thyroid pill in the morning an hour later my BS has only gone up 4 numbers, stayed the same and one day Ok well you get the idea....ive done everything I can to lower my numbers and its working so WOW really bummed to see the weight gain...cant imagine why Do you think Metformin can cause weight gain too? I'm so bummed and disappointed for all my hard work Metformin usually helps people lose weight, so I don't think that is the reason. Plus you are taking a very small dose. Many people when th Continue reading >>
My Diabetes Is Controlled But Why Am I Gaining Weight?
Exercise, eat right, and stay at a healthy weight. These goals are at the core of every type 2 diabetes treatment plan. And, for some people, that’s enough. When it’s not, insulin therapy is one treatment option that can help patients, but one possible side effect is weight gain. Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy This can become a cycle for patients who need to control both diabetes and their weight. It’s frustrating when you feel the treatment is part of the problem. With diabetes, however, you have to get the blood sugar under control first. Insulin is used because it works. The cost of insulin can vary, but lower-cost insulin is associated with more weight gain. In a way, weight gain is a sign that the insulin is working — your body is more effectively utilizing sugar, fat and protein. Your body also has the ability to store them, which means if you don’t adjust your food intake, more of those calories turn to fat. Also, insulin is not necessarily the only factor. When you’re managing your diabetes, your body has a better chance to rehydrate, which also can cause weight gain. Of course, dehydration is a greater risk if you have diabetes, with frequent urination and thirst as two common signs of the condition. Drugs you take for other conditions also sometimes cause weight gain. So, what are your options if weight gain and insulin are an issue? Try these three tips: The simplest answer is to adjust your diet and exercise . Talk to your doctor and to a nutrition specialist about a food plan that takes the insulin effects into account. Work a bit more activity or exercise into each day. Don’t self- Continue reading >>
Does Metformin Help With Weight Loss? (the Answer Is Yes & Here’s Why)
Metformin may be one of the cheapest and most underused weight loss medications out there. Metformin is traditionally reserved for those with diabetes or insulin resistance, but many studies show that it can be effective in overweight or obese patients without diabetes. The only problem? You wouldn't know about it unless you do the research yourself! Use this post to learn everything you need to know about using metformin (both if you have diabetes or if you are simply just overweight): Metformin & How it May Help With Weight Loss Does metformin help with weight loss? The answer is more complex than just a standard "yes" or "no", instead the correct answer is more of a "maybe". What do I mean? Well metformin is a medication that falls into the class of biguanides. The most popular of these medications is metformin (and the topic of our discussion today) which is being used by at least 120 million people worldwide. Classically, metformin is used to treat blood sugar issues, insulin resistance and type II diabetes. It was found a long time ago, that if used for these conditions, metformin does indeed help some patients lose weight. Studies have shown that patients who take metformin with insulin resistance do tend to lose weight - most studies showing a "modest" amount to the tune of around 5-10 pounds. Because these studies have been favorable to some patients (especially those with the conditions listed above), it's normal to ask if it also works for patients who don't have type II diabetes. In order to understand that, we need to understand how metformin works. As it relates to weight loss metformin has powerful actions in 2 main areas: In the mitochondria respiratory chain complex: Activating the mitochondrial pathway is a powerful way to increase energy production an Continue reading >>
Gaining Weight? Your Medication May Be To Blame
Gaining weight or struggling to lose weight is frustrating. You might feel like you’re doing all the “right” things: eating healthful foods, exercising, keeping food records, getting enough sleep, and so on. Yet despite all of your efforts, the scale doesn’t seem to budge. What gives? There are so many factors that affect our weight, and food isn’t always the culprit. One of the factors that may, in part, be contributing to some weight gain is medication. The link between medication and weight If you have diabetes, chances are, you’re taking some form of medication. It might be medication to help you manage your blood sugars. You might also be taking medication to keep your blood pressure or your cholesterol numbers in check. And you might even be taking a medication to help you better cope with the stress of having a chronic condition. While all of these drugs are effective (or else why would you be taking them?), the reality is that, like all medications, some of them have side effects that can make it difficult to reach your weight goal or can even lead to weight gain. To be more specific, these meds might: • Jump-start your appetite, causing you to eat more than you usually might • Slow your metabolism so that you burn fewer calories • Affect how glucose is stored in the body, leading to increased fat storage • Cause fluid retention • Make you feel tired or sluggish, which can prevent you from being as active as you might like The likely culprits The following drugs are those that are mostly likely to affect your weight. However, it’s important to keep in mind that not everybody will gain weight while taking them. And, as with any medication, don’t stop taking it without first talking with your health-care provider. Diabetes medications Ins Continue reading >>
Can You Take Metformin For Weight Loss? A Look At The Numbers
Metformin is a medication said to cause weight loss, but is it true? Should you be worried if you are underweight, or should you use it if you want a slimmer waistline? This article takes a looks at the current evidence and if you can take metformin for weight loss. What is Metformin? Metformin belongs to the class of medications called “oral hypoglycemics.” This means it’s taken by mouth to help reduce blood sugar (glucose) levels. For this reason, metformin is commonly used for the management of type 2 diabetes. How Does Metformin Work? The way metformin works isn’t fully understood yet. However, what is known is that it reduces the production of sugar by liver cells (1). Metformin also improves insulin sensitivity and influences the bacterial community in the gut. It may have anti-inflammatory effects that could be beneficial for metabolic health too (2, 3). Metformin may also cause weight loss by reducing food intake and blocking gastrointestinal absorption of glucose, at least in theory (4). Summary: Commonly prescribed for type 2 diabetes, metformin is a medication that influences the metabolism and absorption of sugar. What is Metformin Used For? Metformin has been approved for treating type 2 diabetes. This medication is also sometimes prescribed for the following: Research continues on other uses for metformin including: Anti-aging or anti-cancer effects (8) Helping manage type 1 diabetes (9) Reducing the risk of heart disease (10). Summary: Metformin has been approved for the management of type 2 diabetes. It is sometimes prescribed for other conditions that involve abnormal blood sugar, such as diabetes during pregnancy. Can You Take Metformin For Weight Loss? Metformin helps manage type 2 diabetes, a health condition associated with being overweight. Continue reading >>
Metformin (glucophage) For Weight Loss
After you eat, sugar goes from your intestines into your bloodstream, and then immediately into your liver. Then your liver releases sugar back into your bloodstream to cause your blood sugar level to rise. To keep blood sugar levels from rising too high, your pancreas release insulin into your bloodstream. Insulin makes you hungry all the time and causes your liver to convert extra calories to fat and it constricts arteries to cause heart attacks. You need insulin to keep blood sugar levels from rising too high to cause diabetes, nerve damage, heart attacks, strokes and kidney damage. Glucophage reduces sugar release from your liver to prevents blood sugar levels from rising too high, so your body doesn't need to produce as much insulin that makes you hungry and causes your liver to make fat (3,13,14). Glucophage lowers insulin levels (4), prevents many of the side effects of diabetes and can be used by people who want to lose weight. However, Glucophage is not effective when your blood is acidic from excess lactic acid and recent research shows that exercise, which raises lactic acid, does not cause blood acid levels to rise enough to reduce Glucophage's benefits (5). Glucophage, itself, does not raise blood lactate levels and is therefore considerably safer than doctors originally thought. Since Glucophage lowers insulin, diabetics should be placed on Glucophage to lower their requirements for all other medications used to treat diabetes (6). A common cause of obesity in women is called polycystic ovary syndrome, which is caused by having high blood levels of insulin. Glucophage helps these women to lose weight (7-12). See the report on Polycystic Ovary Syndrome (PCOS) in the Women's Health section. Glucophage is a safe medication that prevents blood sugar levels fro Continue reading >>
Metformin, Weight Loss & Pcos – Does It Actually Work?
Did you know that one of the main reasons you can't lose weight with PCOS is because of your hormones? It's true, and that's why many women (and physicians) turn to using Metformin to try and help with weight loss. But just because it works for some people doesn't mean it will necessarily work for YOU. Find out why metformin helps with weight loss, but more important what works better and how to finally lose weight if you have PCOS. Insulin & PCOS: Why It's so Important One of the most common medications prescribed for PCOS is metformin. But, PCOS is a hormonal condition which results in weight gain, hair growth on the face, infertility, acne and estrogen/progesterone imbalances. So why is metformin, a medication used to lower blood sugar and treat insulin resistance, used to treat estrogen/progesterone imbalances in women? The logic is quite simple: Most of the symptoms of PCOS (all those listed above) stem from insulin resistanc e! In fact many physicians recommend that ALL women with PCOS should be treated for insulin resistance regardless of what their fasting insulin and fasting blood sugar levels are. This means that the root cause of PCOS (at least the majority of it) is insulin resistance, and this is why metformin is so commonly used to treat. Insulin resistance causes a block of glucose uptake in your skeletal muscles which results in a lower metabolism (and weight gain), insulin also directly acts on your ovaries and adrenals increasing androgens like testosterone and DHEA. It's also the action of insulin on your pituitary that results in increased LH production which over stimulates your ovaries resulting in the characteristic "cysts" of PCOS. High levels of DHEA and testosterone lead to acne and hair growth (hirsutism). But one simple question r Continue reading >>