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Diabetic Angiopathy Of Lower Extremities

Diabetic Angiopathy: Symptoms And Treatment

Diabetic Angiopathy: Symptoms And Treatment

READ Vertebral artery syndrome: symptoms and treatment Diabetic angiopathy is manifested degenerative processes in the blood vessels of the retina and leads to decreased visual acuity. In the initial stages the involvement of the retina are asymptomatic. Patients seek help with extended clinical disease and complain of blurred vision, the appearance of spots before the eyes, sparks and flashes. In the case of rupture of the vessel and infarction of the vitreous body blood patients complain of the appearance of floating spots before the eyes. If time does not seek treatment of a specialist, between the retina and the vitreous body develops strands that are causing its detachment. Retinal detachment leads to severe visual impairment up to complete blindness. Diabetic microangiopathy in the later stages leads to complication such as nephropathy. Her symptoms occur after 10-15 years of diabetes progression or in the case of neglecting treatment. Prior to this pathological process in the renal arteries can be detected only by laboratory methods of examination. A leading figure in this case elevated levels of protein in the urine. In the early period of the complications the level of protein in daily urine will be in the range from 30 to 300 mg, in the later more than 300 mg excretion of protein is a consequence of the violation of the filtering apparatus of the kidneys, which is the development of the pathological process passes first small, and then larger fraction of proteins. In addition to the General manifestations of diabetes, such as thirst, polyuria, dry mucous membranes, with the development of nephropathy have specific symptoms. Leading signs of diabetic nephropathy are swelling, high blood pressure, and General intoxication. In the beginning kidney are swelling o Continue reading >>

Platform.almanhal.com

Platform.almanhal.com

Background: Diabetes Mellitus is one of the most common non-communicable diseases in the world. According to the WHO, 6% of all deaths in Armenia resulted from diabetes in 2002. Complications affecting lower extremities are among the most common complications of diabetes: about 15% of diabetes patients eventually suffer from foot ulceration.Objective: To identify the risk factors leading to the development of angiopathy of lower extremities in Type 2 diabetes patients, 40 years old and above.Methods: This study included 197 cases and 197 controls, selected through simple random sampling. The outcome variable was diabetic angiopathy of lower extremities.Results: There was a statistically significant association between diabetic angiopathy of lower extremities and duration of the disease (OR=1.14; p<0.01), BMI(OR=1.20; p<0.01), smoking status (OR=1.11; p<0.01), poor self-monitoring of blood glucose level (OR=2.78; p<0.01), and hypertension (OR=6.10; p<0.01). The odds of diabetic angiopathy of lower extremities was 10 times higher (OR=10.20; p<0.01) among those diabetes patients who did not check their feet on a regular basis from the moment they were diagnosed with diabetes.Conclusion: This study showed that multiple factors and mechanisms contribute to the development of diabetic angiopathy of lower extremities in Type 2 diabetes patients. Continue reading >>

[diagnosis And Treatment Of Diabetic Angiopathy Of The Lower Extremities].

[diagnosis And Treatment Of Diabetic Angiopathy Of The Lower Extremities].

[Diagnosis and treatment of diabetic angiopathy of the lower extremities]. Dadavani SA , Uspenski LV , Lapchinski VA , Ulanov DA , Artiukhina EG . Experience in the treatment of 77 patients with diabetic angiopathy of the lower limbs is discussed. Various pyonecrotic complications developed in 44% of cases. Laboratory and instrumental diagnostic methods included general clinical, biochemical, and coagulation tests, angiography, dopplerography, and rheovasography. Rheovasography was elaborated in 1952 at the Facultative Surgical Clinic head by N. Elansky and is still an informative method. The management of patients with diabetic angiopathy included correction of carbohydrate metabolism, angioprotectors, anticoagulants, and anti-aggregation agents. In patients with pyonecrotic complications intraarterial infusion of the medicinal agents is preferred, the method is used in the clinic since 1951. Operations were performed on 74% of patients, the character of the intervention was determined by the affection of the vascular bed. Reconstructive operations were conducted on 16% of patients. In the absence of conditions for reconstruction lumbar sympathectomy was undertaken. According to indications, the operation was combined with necrotomy or "minor" amputations. Adequate non-operative therapy, improvement of circulation in the limb by reconstructive operations of sympathectomy save the limb or limit the volume of the amputation. Amputation through the middle third of the leg was performed in 7, exarticulation at Chopart's joint in 2 and at Lisfranc's joint in one, and exarticulation of the toes in 10 patients. No fatal outcomes occurred. The thigh was amputated in 13 patients with moist gangrene for vital indications, mortality was 45%. Timely recognition of affection of th Continue reading >>

[smoking As A Trigger Factor In The Development Of Diabetic Angiopathy Of Lower Extremities In Men With Methylenetetrahydrofolatereductase 677tt Genotype].

[smoking As A Trigger Factor In The Development Of Diabetic Angiopathy Of Lower Extremities In Men With Methylenetetrahydrofolatereductase 677tt Genotype].

Type: Journal Article, English Abstract(lang: rus) Enhanced thrombogenesis in patients with diabetes mellitus (D) is related to genetically determined disorders of the blood coagulation system analogous to those associated with hereditary thrombophilia. The aim of this work was to elucidate the relationship between the functionally significant methylenetetrahydroxyfolatereductase (MTHFR) C677T (rs1801133) gene polymorphism and the development of diabetic angiopathy of lower extremities (DALE) in ethnic Russian men residing in Central Russia (mostly Kursk region). The study involved 434 subjects including 50 with DALE and 384 healthy volunteers. All of them were genotypedfor the MTHFR C677T gene polimorphim by real-time PCR with allele discrimination using TaqMan-probes. No significant differences in the frequency of alleles of MTHFR C677T gene polymorphism were documented between the general samples and sex-matched groups. Stratified sex-specific analysis showed that 677TT genotype is associated with increased risk of DALE in smoking men (OR 4.2; 95% CI 1.28-13.79, p=0.01). In non-smoking men the 677TTgenotype was unrelated to the development of this complication. It is concluded that the risk of DALE is determined by the close relationship between genetic (UTHFR gene) and exogenous (smoking) factors which suggests the multifactorial nature of this pathology. Continue reading >>

Angiopathy In Diabetes Mellitus

Angiopathy In Diabetes Mellitus

Diabetic angiopathy is a kind of complication, which is common among people that suffer from diabetes mellitus. In the course of the disease sides of blood vessels and capillary tubes in particular are decaying and the blood stasis is suffering very much. Diabetic angiopathy is divided into two types of the diseases: micro- and macro-angiopathy. In case of macro-angiopathy, the heart vessels and lower body limbs are affected. While in case with micro-angiopathy most damage is applied to eyes and kidneys. It is known that diabetes mellitus causes hormonal and metabolitic disorders, which are the triggers for development and appearance of diabetic angiopathy. However not all diabetics complain on the angiopathy appearance. This disease appearance depends not only on the hormonal phone of a particular patient, but also on the genetic features of that particular person. Scientists are not unanimous in defining the factors that promote development of diabetic angiopathy, but it is already known that patients of group I and group II are affected in different ways. It is known that people with higher arterial pressure, smokers, drunkards and those who work in harmful environment are prone to appearance of diabetic angiopathy most of all. Diabetic micro-angiopathy is developed through five stages. In the course of this disease, kidneys begin to lower all their activities, also hard arterial hypertension appears and proteinuria appears too (high molecular weight proteins are present in urine). It is highly difficult to distinguish this disease, and generally, to make sure the disease is in progress, it is necessary to conduct needle biopsy of kidneys. Hypertonic angiopathy belongs to micro-angiopathy. Signs of this disease are: varicose veins on the eye fundus, non-uniform arte Continue reading >>

Draft Icd-10-cm/pcs Ms-drgv28 Definitions Manual

Draft Icd-10-cm/pcs Ms-drgv28 Definitions Manual

Draft ICD-10-CM/PCS MS-DRGv28 Definitions Manual MDC 5 Diseases & Disorders of the Circulatory System DRG 299 PERIPHERAL VASCULAR DISORDERS W MCC DRG 300 PERIPHERAL VASCULAR DISORDERS W CC DRG 301 PERIPHERAL VASCULAR DISORDERS W/O CC/MCC Diabetes mellitus due to underlying condition with diabetic peripheral angiopathy without gangrene Diabetes mellitus due to underlying condition with diabetic peripheral angiopathy with gangrene Diabetes mellitus due to underlying condition with other circulatory complications Drug or chemical induced diabetes mellitus with diabetic peripheral angiopathy without gangrene Drug or chemical induced diabetes mellitus with diabetic peripheral angiopathy with gangrene Drug or chemical induced diabetes mellitus with other circulatory complications Type 1 diabetes mellitus with diabetic peripheral angiopathy without gangrene Type 1 diabetes mellitus with diabetic peripheral angiopathy with gangrene Type 1 diabetes mellitus with other circulatory complications Type 2 diabetes mellitus with diabetic peripheral angiopathy without gangrene Type 2 diabetes mellitus with diabetic peripheral angiopathy with gangrene Type 2 diabetes mellitus with other circulatory complications Other specified diabetes mellitus with diabetic peripheral angiopathy without gangrene Other specified diabetes mellitus with diabetic peripheral angiopathy with gangrene Other specified diabetes mellitus with other circulatory complications Dissection of cerebral arteries, nonruptured Unspecified atherosclerosis of native arteries of extremities, right leg Unspecified atherosclerosis of native arteries of extremities, left leg Unspecified atherosclerosis of native arteries of extremities, bilateral legs Unspecified atherosclerosis of native arteries of extremities, other extre Continue reading >>

Angiopathy Of The Lower Extremities

Angiopathy Of The Lower Extremities

Angiopathy of the lower extremities develops inMost cases with diabetes. The disease is characterized by a change in small arterial vessels. Namely: their walls thicken, and their permeability deteriorates. All this leads to a violation of blood flow and problems with the blood supply of those organs to which the damaged vessels lead. The main symptoms of diabetic angiopathy of the lower extremities What symptoms appear with angiopathy,Depends on the degree of vascular damage. Another important fact: what kind of vessels are damaged - small or large. At the initial stages, the ailment behaves quite imperceptibly. And still some changes can be considered: Numbness, cold snap, creepy. These symptoms of lower extremity angiopathy in diabetes mellitus usually pay attention in the first place. Unpleasant sensations can appear everywhere: on feet, in the field of calves or shins. Dryness, redness, peeling. Sometimes these symptoms are added to hair loss at the place of the foot, which receives less nutrients. Pain, cramps. Soreness is a sign that the limb is experiencing oxygen starvation for a long time. Trophic ulcers. When this symptom arterial angiopathyLower extremities begins to need urgent treatment. This is the final stage of the disease. The tissue resistance decreases, local immunity is greatly reduced. If you do not begin treatment at this stage, tissue necrosis will develop. Treatment of angiopathy of lower extremities Begin the treatment should be with the control of diabetes. It's good if angiopathy is detected at an early stage. In this case, there is a chance to restore blood flow in the vessels. Continue reading >>

Diabetic Angiopathy | Almagia

Diabetic Angiopathy | Almagia

Diabetic antipathy is the vascular complication of prolongedly elapsing uncompensated diabetes mellitus and disturbances of carbohydrate and lipid metabolism associated with it. Pathology is developed in both insulin-dependent and non-insulin-dependent form of diabetes mellitus. The primary localization of lesion is lower extremities. Methods of destruction from a weakly expressed trophic disorders to trophic ulcers and diabetic foot gangrene, which leads to the amputation of the limb. ALMAG is used as required part of the complex therapy of angiopathy in the pre-gangrene period. The magnetic field of ALMAG provides an anaesthetizing, anti-spasmodic effect, a beneficial effect on carbohydrate, lipid and protein metabolisms, improves the collateral blood circulation (collateral this the lateral vessel, which achieves the roundabout blood stream, passing the stopped up vessel). Area of the foot affected by diabetic angiopathy of the vessels is wrapped around by ALMAG starting at the rear of the foot (see Fig. 24). The first inductor is placed closed to the knee, the last one on the foot itself. This procedure should be performed twice a day. In case of vascular lesion of the thigh segment, the procedure with ALMAG is carried out once a day with the procedure beginning on the front-inner surface of the thigh, then on the lower leg (shin) (see Fig. 24). If the Disease has affected vessels throughout the entire length of lower extremity, inductors are placed on the affected area, alternately (see description above), not forgetting about the correct location of the inductors the first is closer to the torso, the last to the foot. The most optimal position for the procedure -is while the patient is lying on his back. Sitting position can be used as an option. During the cours Continue reading >>

What Is Diabetic Peripheral Angiopathy: Causes, Symptoms, Diagnosis, And Treatment

What Is Diabetic Peripheral Angiopathy: Causes, Symptoms, Diagnosis, And Treatment

What is Diabetic Peripheral Angiopathy: Causes, Symptoms, Diagnosis, and Treatment Diabetic peripheral angiopathy (DPA) is a blood vessel disease caused by high blood sugar levels (glucose). It is one of the most common complications of diabetes. It affects blood vessels that carry oxygen-rich blood away from the heart. These vessels supply blood to many different parts of the body. However, DPA often affects blood vessels in the legs and feet. Diabetes is a chronic disease that occurs when the body does not produce enough insulin. It can also occur if cells do not respond well to insulin. Diabetes prevents glucose (the bodys main source of energy) from reaching the cells. Thus, glucose builds up in the blood. DPA has two main types, namely macroangiopathy and microangiopathy. The former causes blood clots to form in large blood vessels and cause a blockage. This prevents blood from reaching vital organs, such as the heart and the brain. Thus, it increases the risk of heart attack and stroke . Microangiopathy, on the other hand, affects the smaller blood vessels. The condition makes them thick and weak. As a result, the flow of blood throughout the body is slowed down. This increases the risk of diabetic retinopathy (which can lead to blindness) and kidney disease. Diabetic peripheral angiopathy occurs due to uncontrolled diabetes. Diabetes increases the risk of atherosclerosis . This refers to the build-up of plaque in the arteries. Plaque is made up of substances found in blood, such as calcium and cholesterol. Too much plaque in the arteries can limit the amount of blood that flows through the affected blood vessel. It can also completely obstruct or cut off blood supply to other body parts. Without enough blood supply, tissues on the affected body parts will not su Continue reading >>

Diabetic Angiopathy Of The Lower Extremities: Treatment And Symptoms

Diabetic Angiopathy Of The Lower Extremities: Treatment And Symptoms

All this is done using a special diet. It is composed of purely individual way for each patient. It is limited to easily digestible carbohydrates and animal fats. Diet alone will not be effective, it must be supplemented with potassium supplements, anabolic hormones, andhypoglycemic agents, of which the most preferred is gliclazide. Also needs to continue therapy with insulin or other analogues. In addition, if carried out comprehensive treatment, we cannot dispense with any of angioprotectors, for example, parmidina, dobezilata or something similar. It is important to maintain a constant level of cholesterol in the blood, because angiospasticskie changes in the blood usually occur at a high level of lipoproteins. If their level is too high, then the destructive processes in the lower extremities and other parts of the body will happen much faster than we would like. Blood also needs to be thin, because its low viscosity in small capillaries it will get much easier, and therefore the problems will be much less pronounced. If you have started to receive the changes of ulcerative-necrotic type, conservative treatment may be less effective necrotic isolated areas can begin to be mummified or even reject. Because in this case, drugs are introduced, usually intra-arterial. If the patient has diabetic disease is in this stage that started to develop limb ischemia, is a special procedure that bears the name of "gravitational plasmapheresis". It helps to minimize ischemic pain, make the wound healing, and rejection of necrotic parts more fast - and it will help the person more likely to cope with the problem and begin to feel much more comfortable. Can also be surgical treatment, such as lumbar sympathectomy affecting the walls of the arteries. More expensive, but quite effect Continue reading >>

Code Icd-10 Cm - Diagnosis Description

Code Icd-10 Cm - Diagnosis Description

ICD-10 CM - Diagnosis E08.51 Diabetes mellitus due to underlying condition with diabetic peripheral angiopathy without gangrene E08.52 Diabetes mellitus due to underlying condition with diabetic peripheral angiopathy with gangrene E09.51 Drug or chemical induced diabetes mellitus with diabetic peripheral angiopathy without gangrene E09.52 Drug or chemical induced diabetes mellitus with diabetic peripheral angiopathy with gangrene E10.51 Type 1 diabetes mellitus with diabetic peripheral angiopathy without gangrene E10.52 Type 1 diabetes mellitus with diabetic peripheral angiopathy with gangrene E11.51 Type 2 diabetes mellitus with diabetic peripheral angiopathy without gangrene E11.52 Type 2 diabetes mellitus with diabetic peripheral angiopathy with gangrene E13.51 Other specified diabetes mellitus with diabetic peripheral angiopathy without gangrene E13.52 Other specified diabetes mellitus with diabetic peripheral angiopathy with gangrene E71.30 Disorder of fatty-acid metabolism, unspecified E75.21 Fabry (-Anderson) disease E75.22 Gaucher disease E75.240 Niemann-Pick disease type A E75.241 Niemann-Pick disease type B E75.242 Niemann-Pick disease type C E75.243 Niemann-Pick disease type D E75.248 Other Niemann-Pick disease E75.249 Niemann-Pick disease, unspecified E75.3 Sphingolipidosis, unspecified E75.5 Other lipid storage disorders E75.6 Lipid storage disorder, unspecified E77.0 Defects in post-translational modification of lysosomal enzymes E77.1 Defects in glycoprotein degradation E77.8 Other disorders of glycoprotein metabolism E77.9 Disorder of glycoprotein metabolism, unspecified E78.00 Pure hypercholesterolemia, unspecified New Code effective 10/1/2016 E78.01 Familial hypercholesterolemia New Code effective 10/1/2016 E78.1 Pure hyperglyceridemia E78.2 Mixed hype Continue reading >>

Angiopathy - Causes, Symptoms, Symptoms And Treatment

Angiopathy - Causes, Symptoms, Symptoms And Treatment

Angiopathy the defeat of blood vessels in various ailments, which violates their full functioning and destroys the walls. The pathological process can affect different areas of the body and vessels of various sizes from small capillaries to large vessels. If angiopathy progresses over a long period of time, then it is fraught with the development of irreversible changes in the organs in the human body (due to a chronic disruption of the supply of their blood). The pathogenesis of the effect on the vessels with each form of pathology is different, but the result of this effect is always the same the necrosis of tissues that fed the affected blood vessel. In the International Classification of Diseases (ICD 10), angiopathy has its own code and a list of diseases that can cause it. The main reasons for the appearance of angiopathy of any of the types include: Medical statistics are such that most often in patients diagnosed diabetic form of the disease (this is due to the prevalence of the incidence of diabetes). Also often on the background of diabetes, angiopathy of the lower extremities develops. With this kind of disease, there is a thickening of the walls of the vessels and a narrowing of the lumen of the arteries in the legs. These processes together constitute a favorable ground for the progression of atherosclerosis. Diabetic angiopathy can affect not only the vessels of the lower extremities. It negatively affects the work of the kidneys, the retina of the eye, and also the heart. If you do not treat this type of disease for a long time, it can lead to severe consequences, the most sad of which is disability. The reasons for the manifestation of hypertensive angiopathy include: genetic predisposition, excessive consumption of alcoholic beverages, as well as hyper Continue reading >>

Angiopathy | Definition Of Angiopathy By Medical Dictionary

Angiopathy | Definition Of Angiopathy By Medical Dictionary

Angiopathy | definition of angiopathy by Medical dictionary any disease of the blood vessels or lymphatics. /angiopathy/ (anje-opah-the) any disease of the vessels.angiopathic Any of several diseases of the blood or lymph vessels. Etymology: Gk, angeion, vessel, pathos, disease A generic term for any disease of blood vessels (arteries, veins, capillaries). A disease of blood vesselsarteries, veins, capillaries. See Cerebral amyloid angiopathy , Diabetic angiopathy , Microangiopathy . Any disease of the blood or lymph vessels. Any disease of the blood vessels or lymphatics. Want to thank TFD for its existence? Tell a friend about us , add a link to this page, or visit the webmaster's page for free fun content . Because of the potentially devastating nature of this disorder, it is important for the nurse to recognize the symptoms of postpartum cerebral angiopathy early and be knowledgeable about the possible causes, common symptoms, and usual treatments required to prevent neurological deficits. Counseling regarding avoiding future pregnancies should also be considered, because postpartum cerebral angiopathy has been shown to recur (Ursell et al. This patient closely resembled the classic picture of postpartum cerebral angiopathy as evidenced by her presenting symptoms, neurological presentation, magnetic resonance angiogram, and angiographic findings. Recurrent intracranial hemorrhage because of postpartum cerebral angiopathy. Postpartum cerebral angiopathy: a case study Patients with amyloid angiopathy may have dementia preceding the haemorrhage. Intracranial haemorrhage: increasing use of antiplatelet medication has led to an increase in intracranial haemorrhage as a cause of stroke over the past decade The following groups were included in the study:-endomyocardial f Continue reading >>

Angiopathy - Wikipedia

Angiopathy - Wikipedia

Angiopathy is the generic term for a disease of the blood vessels ( arteries , veins , and capillaries ). [1] The best known and most prevalent angiopathy is diabetic angiopathy , a common complication of chronic diabetes . There are two types of angiopathy: macroangiopathy and microangiopathy . In macroangiopathy, atherosclerosis and a resultant blood clot forms on the large blood vessels, sticks to the vessel walls, and blocks the flow of blood . Macroangiopathy may cause other complications, such as ischemic heart disease , stroke and peripheral vascular disease which contributes to the diabetic foot ulcers and the risk of amputation. In microangiopathy, the walls of the smaller blood vessels become so thick and weak that they bleed , leak protein , and slow the flow of blood through the body. The decrease of blood flow through stenosis or clot formation impairs the flow of oxygen to cells and biological tissues (called ischemia ) and leads to cellular death ( necrosis and gangrene , which in turn may require amputation ). Thus, tissues which are very sensitive to oxygen levels, such as the retina , develop microangiopathy and may cause blindness (so-called proliferative diabetic retinopathy ). Damage to nerve cells may cause peripheral neuropathy , and to kidney cells, diabetic nephropathy ( Kimmelstiel-Wilson syndrome ). Continue reading >>

Diabetic Angiopathy: Causes, Symptoms, Diagnosis, Treatment | Competently About Health On Ilive

Diabetic Angiopathy: Causes, Symptoms, Diagnosis, Treatment | Competently About Health On Ilive

The first signs of vascular disease are manifested in lowering the temperature of the lower extremities, a weak pulse or a complete absence of arterial pulse on the legs, the skin is dry, cyanotic in color, in places redness may occur, the hair on the affected part of the skin falls out, and ischemic swelling is noticeable. Diabetic angiopathy is a lesion of small vessels of the lower extremities in diabetes mellitus. The causes of the development of this disease lie in the metabolic disorders caused by changes in blood vessels in diabetes . The causes of diabetic angiopathy also depend on the following factors: Disruption of the exchange of mucoproteins and lipids, which affects the state of the vascular system. The degree and severity of the course of diabetes mellitus, the duration of the disease. In secondary diabetes, which is preceded by a pancreatic injury, partial amputation or pancreatitis, the incidence of diabetic angiopathy increases many-fold. Also, changes in blood vessels are recorded in laboratory studies based on the introduction of the contrusulant hormone or physical effects on the islets of the pancreas. Also, there is a high likelihood of a hereditary transmission of the disease, four possible options. In addition, the category of risk includes those people who, in addition to hereditary endocrine pathology, have metabolic disorders. The causes of diabetic angiopathy, as a rule, speak of a dangerous predisposition to this disease. Therefore, it is important to systematically undergo examinations to prevent the development of the disease and severe consequences. By the nature of the lesions of the vessels distinguish between microangiopathy (changes in capillaries) and macroangiopathy (damage to the arterial and venous system). Symptoms of diabetic Continue reading >>

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