
Nutrition And Wound Healing
There are various types of wounds, such as pressure ulcers, surgical wounds, chronic wounds, diabetic ulcers, and acute burns. Wound healing is a complex process that involves following a distinct care plan. Balanced nutrition also plays a part in helping with wound healing. This animated video can help you understand how protein and the intake of other key nutrients plays a crucial role in pressure injury (ulcer) healing. Check it out! Protein is a very important nutrient involved in wound healing. If you have a wound, it is recommended that you consume at least 50% more protein each day.1 For example, if you have a wound, it is recommended to consume 95 grams of protein per day.2 However, many adults who need extra protein get less than 50% of the protein they need.3 Need Product Wounds or pressure ulcer stage 1 or stage 2 Pro-Stat® Sugar Free Chronic wounds or pressure ulcer stage 3 or 4 Pro-Stat® Sugar Free AWC (Advanced Wound Care) Protein for dialysis Pro-Stat® Renal Care Protein for surgery wounds and ICU critical care Pro-Stat® MAX Pro-Stat is a medical food to be used under medical supervision. 1. National Pressure Ulcer Advisory Panel, European Pressure Ulcer Advisory Panel and Pan Pacific Pressure Injury Alliance. Prevention and Treatment of Pressure Ulcers: Clinical Practice Guideline. 2nd ed. Australia: Cambridge Media, 2014. 2. Based upon the NPUAP guidelines of 1.25-1.5g/kg/day. 3. Hoffer LJ. Am J Clin Nutr 2012;96:591–600. ©2016 Nutricia North America Continue reading >>

If One Has Diabetes How Long It'll Take To Heal Wound On Toes?
It would take more time than ideally it takes for a person without diabetes also it depends on how big your wound is. I would suggest you to keep your blood sugar levels in control, also it would be great if you consult a doctor if your wound is big as he may suggest you some antibiotics to reduce chances of infection and for fast healing. Also keep the wound area clean. If Blister or pus gets formed then problem might escalate. In India every year 10 lakh diabetic people loose their legs because of dreadful infection cause by these wounds. Please take special care of yourself. You can additionally drop an email at [email protected] or visit Diab.in (online website to spread awareness about diabetes in Hindi) to know more about diabetes or clear any further doubts. Continue reading >>

Nutricia Suggestion Engine - Conditions
Wound healing Wound Care A wound is defined as a break in the continuity of the skin and can be caused by injury, surgery, pressure, or friction. The skin acts as a protective barrier so any damage to it increases susceptibility to infection. An acute wound is a wound which usually heals in an ordered, timely fashion. Acute wounds typically fall into one of two categories: traumatic wounds (a wound caused by a fall or accident) and surgical wounds (caused by a surgical cut during an operation). A chronic wound is a wound that develops over a longer period of time. Chronic wounds may not heal in an orderly set of stages and in a predictable amount of time. Examples of chronic wounds include pressure ulcers (also called bed sores, pressure sores or pressure wounds), leg ulcers, diabetic wounds (including diabetic foot and diabetic ulcers). Impaired or delayed wound healing refers to a wound that does not heal over time. Wounds which are slow to heal, or which do not heal, cause patients severe emotional and physical stress. Good wound care aims to support the wound healing process through the use of dressings, pressure relief, and correct nutrition. Wound care management Nutrition for wound healing Wound care management If you have a wound you may be receiving treatment from a variety of healthcare professionals, in addition to your doctor or surgeon, you may also receive treatment from a: Tissue viability nurse, public health nurse or wound care nurse – this is a nurse who manages the day to day treatment of your wound. The treatment plan may involve: Wound assessment – the nurse will carefully examine and evaluate your wound to determine how best to treat it. Wound treatment – this may involve the use of dressings, wound debridement (removal of infected or dead ti Continue reading >>

Effect Of Oral Nutritional Supplementation On Wound Healing In Diabetic Foot Ulcers: A Prospective Randomized Controlled Trial
Abstract Among people with diabetes, 10–25% will experience a foot ulcer. Research has shown that supplementation with arginine, glutamine and β-hydroxy-β-methylbutyrate may improve wound repair. This study tested whether such supplementation would improve healing of foot ulcers in persons with diabetes. Along with standard of care, 270 subjects received, in a double-blinded fashion, (twice per day) either arginine, glutamine and β-hydroxy-β-methylbutyrate or a control drink for 16 weeks. The proportion of subjects with total wound closure and time to complete healing was assessed. In a post-hoc analysis, the interaction of serum albumin or limb perfusion, as measured by ankle–brachial index, and supplementation on healing was investigated. Overall, there were no group differences in wound closure or time to wound healing at week 16. However, in subjects with an albumin level of ≤ 40 g/l and/or an ankle–brachial index of < 1.0, a significantly greater proportion of subjects in the arginine, glutamine and β-hydroxy-β-methylbutyrate group healed at week 16 compared with control subjects (P = 0.03 and 0.008, respectively). Those with low albumin or decreased limb perfusion in the supplementation group were 1.70 (95% CI 1.04–2.79) and 1.66 (95% CI 1.15–2.38) times more likely to heal. While no differences in healing were identified with supplementation in non-ischaemic patients or those with normal albumin, addition of arginine, glutamine and β-hydroxy-β-methylbutyrate as an adjunct to standard of care may improve healing of diabetic foot ulcers in patients with risk of poor limb perfusion and/or low albumin levels. Further investigation involving arginine, glutamine and β-hydroxy-β-methylbutyrate in these high-risk subgroups might prove clinically val Continue reading >>
- A Website to Promote Physical Activity in People With Type 2 Diabetes Living in Remote or Rural Locations: Feasibility Pilot Randomized Controlled Trial
- Effect of Probiotics on Glucose and Lipid Metabolism in Type 2 Diabetes Mellitus: A Meta-Analysis of 12 Randomized Controlled Trials
- Diabetes, Foot Care and Foot Ulcers

Skin Care & The Wound Clinic: Increasing Skin Nutrition With Small Molecule Technology To Promote Healing Of Diabetic Foot Ulcers
Diabetes mellitus has been described as “one of the main threats to human health of the 21st century.”1 According to the most recent (2012) estimate from the American Diabetes Association, 29.1 million Americans live with diabetes.2 The percentage of Americans with diagnosed (or undiagnosed) diabetes continues to rise, and the number of people living with type 2 diabetes is likely to reach epidemic proportions, due in part to poor lifestyle choices such as the consumption of processed foods and poor nutrition habits placing an increasing population at risk.3 In fact, one study projects as many as one in three Americans will live with diabetes by 2050.4 Diabetes is frequently undiagnosed due to many symptoms being ignored, including frequent urination, increased fatigue, and irritability.5 Other early warning signs include certain skin issues.6,7 In fact, at least 30% of patients experience some skin complication, and patients living with diabetes frequently have wounds that are difficult to heal.5,6,8Hyperglycemia affects skin homeostasis by inhibiting fibroblast cell migration,9,10 keratinocyte proliferation, differentiation, migration, and protein biosynthesis, as well as by inducing endothelial cell apoptosis. Hyperglycemia also decreases immune cell functions, including phagocytosis and chemotaxis, and the prevalence of skin infections is frequently increased among diabetes patients.8,11 In addition, patients living with diabetes have up to a 25% lifetime risk of developing a diabetic foot ulcer (DFU),12and DFUs are a leading cause of morbidity that is often preceded by pain, suffering, and poor quality of life for these patients. Furthermore, DFUs are the cause of 84% of all diabetes-related lower leg amputations.13 Increasing Skin Nutrients, Decreasing Oxidati Continue reading >>

How Your Diet Can Aid In Wound Healing
Without proper nutrition, the whole process of wound healing can be negatively impacted. Your diet during recovery plays a critical role in how fast your wound heals, how strong the wound tissue becomes, the duration of the recovery period and how well your body fights off infection. A poor diet can turn a normal wound into a chronic wound that never seems to be get better. The Catabolic Phase Even a small wound can alter the way your body metabolizes nutrients. As the body attempts to heal itself from a wound, it will create stress hormones and divert extra resources – carbohydrates, fats, proteins, antioxidants and more – to the creation of new tissue. This is referred to as the catabolic phase of healing. Your metabolism essentially speeds up during this process. If the catabolic phase drags on too long, protein energy malnutrition (PEM) can set in. This begins a negative cycle which slows wound healing and deteriorates your health. Your body sends extra protein to deal with the wound and, as a consequence, other important body systems and organs don't receive enough protein. This leads to reduced muscle mass and delayed wound healing. Protein is the most important aspect of your diet when healing from a wound. Energy (calories from carbohydrates and fats), amino acids, antioxidants and minerals (zinc) are also important. Your dietary needs will be calculated on an individual basis, and your doctor or nutritionist may adjust the levels of each nutrient to facilitate healing. The following guidelines are only generalizations, but will give you an idea of what your diet should include. Protein Protein helps repair the damaged tissue from your wound. You'll want to take in more protein than usual to help the healing process. This means 2 to 3 servings of protein a d Continue reading >>

Nutritional Supplementation For Diabetic Foot Ulcers: The First Rct.
Abstract OBJECTIVE: To determine if oral nutritional supplementation improved wound healing in malnourished patients with diabetic foot ulcers when compared with a placebo. METHOD: This prospective randomised controlled double-blind trial involved patients aged over 60 with diabetes mellitus and a Wagner grade I-II foot ulcer of over four weeks' duration. Patients received either 400 ml (400 kcal) oral nutritional supplementation (n = 26) or 400 ml placebo (n = 27) daily for six months. Patients were followed monthly for six months and after one and two years. RESULTS: A third of the patients were classified as having protein-energy malnutrition at inclusion, with no difference between the two groups. Critical leg ischaemia was more common in the intervention group than in the placebo group (p = 0.008). Nine patients in the intervention group (35%) and four in the placebo group (15%) dropped out of the study (not significant). Of those who completed the study, the wound had healed at six months in eight out of 23 patients (41%) (placebo) and in seven out of 17 (35%) (intervention) (not significant). Twenty-four per cent of patients with protein-energy malnutrition at inclusion had healed at six months compared with 50% of those without it (not significant). CONCLUSION: This is the first study to evaluate the possible benefits of nutritional supplementation on diabetic foot ulcers. A third of patients were malnourished. We encountered several methodological problems and were unable to demonstrate an improved wound healing rate in these patients. Continue reading >>

Nutrition 411: The Diabetic Foot Ulcer — Can Diet Make A Difference?
The statistics are shocking: 25.8 million Americans, or 8.3% of the population of the US, has been diagnosed with diabetes.1 Among the complications of the disease are diabetic foot ulcers (DFUs), which affect as many as 20% of patients with diabetes during their lifetime.2 DFUs can significantly impair a patient’s quality of life, require prolonged hospitalization, involve infection and gangrene, and may ultimately result in amputation. The National Pressure Ulcer Advisory Panel (NPUAP) has established evidence-based nutrition recommendations for the prevention and treatment of pressure ulcers. These guidelines focus on increasing micro- and macronutrients to promote wound healing.3 Unfortunately, no such guidelines exist for treating DFUs, and it is unclear if recommendations for pressure ulcers can be extrapolated to DFUs. However, it appears that nutrition does play an important role. A poor diet can result in altered immune function, malnutrition, and poor glycemic control, all of which are risk factors for poor healing.4,5 Achieving and maintaining a healthy body weight can help maximize wound healing because glycemic control can be negatively affected by obesity.6 Healthcare professionals (HCPs) should encourage patients with DFUs to consume a healthy diet that contains nutrient-dense foods. A registered dietitian (RD) skilled in medical nutrition therapy for diabetes can assess, treat, and monitor patients with DFUs to help them meet their complex nutritional needs. Immune Function and Malnutrition Compromised immune function is one factor associated with nonhealing wounds; it affects wound healing in a number of ways.4 Protein-energy malnutrition is associated with impaired immunocompetence, including depressed cell-mediated immunity and phagocyte dysfunction Continue reading >>

Effect Of Oral Nutritional Supplementation On Wound Healing In Diabetic Foot Ulcers: A Prospective Randomized Controlled Trial.
Abstract AIMS: Among people with diabetes, 10-25% will experience a foot ulcer. Research has shown that supplementation with arginine, glutamine and β-hydroxy-β-methylbutyrate may improve wound repair. This study tested whether such supplementation would improve healing of foot ulcers in persons with diabetes. METHODS: Along with standard of care, 270 subjects received, in a double-blinded fashion, (twice per day) either arginine, glutamine and β-hydroxy-β-methylbutyrate or a control drink for 16 weeks. The proportion of subjects with total wound closure and time to complete healing was assessed. In a post-hoc analysis, the interaction of serum albumin or limb perfusion, as measured by ankle-brachial index, and supplementation on healing was investigated. RESULTS: Overall, there were no group differences in wound closure or time to wound healing at week 16. However, in subjects with an albumin level of ≤ 40 g/l and/or an ankle-brachial index of < 1.0, a significantly greater proportion of subjects in the arginine, glutamine and β-hydroxy-β-methylbutyrate group healed at week 16 compared with control subjects (P = 0.03 and 0.008, respectively). Those with low albumin or decreased limb perfusion in the supplementation group were 1.70 (95% CI 1.04-2.79) and 1.66 (95% CI 1.15-2.38) times more likely to heal. CONCLUSIONS: While no differences in healing were identified with supplementation in non-ischaemic patients or those with normal albumin, addition of arginine, glutamine and β-hydroxy-β-methylbutyrate as an adjunct to standard of care may improve healing of diabetic foot ulcers in patients with risk of poor limb perfusion and/or low albumin levels. Further investigation involving arginine, glutamine and β-hydroxy-β-methylbutyrate in these high-risk subgroups Continue reading >>
- A Website to Promote Physical Activity in People With Type 2 Diabetes Living in Remote or Rural Locations: Feasibility Pilot Randomized Controlled Trial
- Effect of Probiotics on Glucose and Lipid Metabolism in Type 2 Diabetes Mellitus: A Meta-Analysis of 12 Randomized Controlled Trials
- Diabetes, Foot Care and Foot Ulcers

What Factors Help To Determine How Fast Wounds Heal For A Specific Person?
Wound healing is a dynamic physiological process, and the rate and quality of wound healing depends on many factors. Depending on the size, type, and location of wound the answer may vary a bit. Wound healing also depends on your psychological stress levels, any underlying health condition e.g., diabetes) and whether you are getting sufficient nutrients required to maintain optimum health. I happened to work on a project funded by the burn care unit of Shriners Hospitals for Children in Boston, specifically on understanding how isolation stress delays wound healing in pediatric patients with secondary and tertiary burn wounds, and how can we enrich their immediate environment to reduce their stress levels and promote faster wound healing. So my answer is based on what I learnt during the project. Here are some factors, I can think of, that affect the time and quality of wound healing. the amount of trauma on your tissues (depth of wound etc.) Blood supply to the wounded area. Infection Temperature of the wound bed (i.e. area of the wound) Moisture content of the wound bed Techniques used to manage the wound (dressings, bandages, sutures etc.) The general consensus among physicians I interacted with was that wound bed should be moist/wet for faster healing. Moist environment helps the inflammation stage of wound healing and reduces chances of infection. Moist environment results in slow and normal scab formation, beneath which debridement process starts where neutrophils and macrophages digest and remove dead (necrotic) tissues, cell debris, microbial contaminants, clearing the wound of any cellular barriers to healing process, and bring essential nutrients and oxygen through angiogenesis to the wound area to start epithelialization. Wound healing is a systemic process, Continue reading >>

What’s The Connection Between Diabetes And Wound Healing?
Diabetes is a result of your body’s inability to produce or use insulin. Insulin is a hormone that allows your body to turn glucose, or sugar, into energy. If your body has difficulty metabolizing glucose, it can lead to high blood sugar levels. This can affect your body’s ability to heal wounds. In people with diabetes, wounds tend to heal more slowly and progress more quickly, so it’s important to know what to look out for. Although cuts, grazes, scratches, and blisters can occur anywhere on the body, the feet are one of the most common places of injury. A small wound on the foot can quickly develop into a foot ulcer. Foot ulcers can become serious if left untreated. Between 14 and 24 percent of people who have diabetes and develop an ulcer will end up having a lower limb amputation. For this reason, it’s crucial that you do regular self-checks and closely monitor any wounds closely. Catching wounds early is the only way to reduce your risk of complications. Keep reading to learn more about the healing process, ways to speed the healing process along, and how to improve your body’s healing powers long-term. When you have diabetes, a number of factors can affect your body’s ability to heal wounds. High blood sugar levels Your blood sugar level is the main factor in how quickly your wound will heal. When your blood sugar level is higher than normal, it: prevents nutrients and oxygen from energizing cells prevents your immune system from functioning efficiently increases inflammation in the body’s cells These effects slow down wound healing. Neuropathy Peripheral neuropathy can also result from having blood sugar levels that are consistently higher than normal. Over time, damage occurs to the nerves and vessels. This can cause the affected areas to lose sen Continue reading >>

Nutrition Supplementation For Diabetic Wound Healing: A Systematic Review Of Current Literature
Abstract There are 25.8 million people with diabetes in the United States (Centers for Disease Control and Prevention 2011 National Diabetes Fact Sheet). This number is expected to increase by 1 million per year. Diabetic foot ulcers (DFUs) occur in patients with a history of poorly controlled blood glucose. Almost 30% of people with diabetes aged 40 years or older experience DFUs caused by an impaired nerve sensation. It is one of the more persistent types of chronic wounds, which poses an economic burden on individuals and society and reduces the quality of life of patients and their families. This paper reviews the efficacy of nutrition supplementation in diabetic wound healing, including both human and animal studies. Using Preferred Reporting Items for Systematic Reviews and Meta-Analyses methods, the search was conducted in PubMed and ISI's Web of Science databases. Studies in which diabetic wounds/foot ulcers were treated with specific nutritional or herbal suplements were selected. This review includes 4 human and 9 animal studies that met the criteria of the search. Positive outcomes in the human studies were not significant while the nutritional supplements used in the animal studies were effective and promoted wound healing. The most notable effect of supplementation with curcumin, L-Arginine, or vitamin E have been shown in animal sudies. More human studies need to be conducted to determine the efficacy of these nutritional supplements in promoting wound healing. Discover the world's research 14+ million members 100+ million publications 700k+ research projects Join for free Continue reading >>
- Caffeinated and Decaffeinated Coffee Consumption and Risk of Type 2 Diabetes: A Systematic Review and a Dose-Response Meta-analysis
- Influence of uncontrolled diabetes mellitus on periodontal tissues during orthodontic tooth movement: a systematic review of animal studies
- Type 1 Diabetes and Polycystic Ovary Syndrome: Systematic Review and Meta-analysis

Foods & Wound Healing
People with diabetes do not heal as efficiently as people with normal blood sugar levels. Certain foods can also help keep your blood sugar optimal. Protein helps to repair tissue: Fish Shellfish Eggs (egg whites have protein and no cholesterol) Cheese (low fat is better for your heart) Poultry Lean meat Nut butters (peanut butter, almond butter, cashew butter, etc.) Carbohydrates give you energy: Starch (bread – whole grains are best – cereal, noodles, rice, barley, kasha) Starchy vegetables (sweet or white potatoes, corn, peas, beans) Non-starchy vegetables (broccoli, green beans, asparagus, salad greens) Fruit Milk (drinking milk, soymilk or yogurt) Fat allows you to absorb your fat soluble vitamins – A, D, E, K: Oil (olive and canola oil are best for your heart) Nuts (are good for your heart and health) Avocado (is good for your heart) Margarine (pick one without trans fat) Butter (use more sparingly) The following vitamins are excellent to heal wounds most efficiently: Vitamin C – foods with high levels: Peppers (especially red) Kiwi fruit Tomatoes Citrus fruits (oranges, grapefruits) Broccoli Vitamin A – foods with high levels: Orange colored fruits/vegetables Dark green leafy vegetables Vitamin E – foods with high levels: Whole grains Wheat germ Dark leafy green vegetables Eggs** Nuts and seeds Vitamin B – foods with high levels: Whole grains (wheat and oats) Fish and seafood Poultry and meat Eggs** Zinc – foods with high levels: Oysters (very high) Protein Beans ** Egg yolks contain vitamins and cholesterol while egg whites contain protein The goal of Destination Diabetes is to be a useful and credible resource for the more than 20 million children and adults who have diabetes in the U.S. and their families. Destination Diabetes provides informat Continue reading >>

Diabetic Wound Healing Through Nutrition And Glycemic Control
Diabetes has quickly become one of the most complex health challenges of the 21st century. In 2010, a total of 10.9 million US residents ages 65 years and older were reported to be living with diabetes.1 Currently, it is the seventh-leading cause of death in the US, totaling 4.6 million deaths in 2011 (with healthcare expenditures reaching more than $471 billion.)2 A condition that increases one’s risk for heart disease and stroke, diabetes is also the leading cause of kidney failure, new cases of blindness among adults, and non-traumatic lower-limb amputations. Approximately 15% of individuals who live with diabetes develop a foot ulcer, and 84% of this population will end up with lower-leg amputations.3 Several factors can disrupt wound healing. Without proper nutrition, a normal wound can rapidly become a chronic, infected wound. However, it is possible for wound care providers to reduce the huge economic burden and life-threatening complications of diabetes by implementing timely, easy-to-use interventions. Comprehensive diet and nutrition management have been shown to promote optimal glycemic control and facilitate wound prevention and healing. As such, all healthcare professionals should know how to adequately manage blood glucose levels to support wound healing in patients living with diabetes. This article explains how uncontrolled blood sugar impairs wound healing and offers practical nutrition recommendations and guidelines that promote healing, as well as simple suggestions to prevent further complications and comorbidities. Effect of Diabetes Diabetes often causes slow-healing wounds that can worsen rapidly — with elevated blood glucose levels serving as the initial barrier to healing. Thus, achieving optimal glycemic control is imperative. Hyperglycemia Continue reading >>
- The effect of a low-carbohydrate, ketogenic diet versus a low-glycemic index diet on glycemic control in type 2 diabetes mellitus
- Early Glycemic Control and Magnitude of HbA1c Reduction Predict Cardiovascular Events and Mortality: Population-Based Cohort Study of 24,752 Metformin Initiators
- Association of Glycemic Variability in Type 1 Diabetes With Progression of Microvascular Outcomes in the Diabetes Control and Complications Trial

Current Perspectives On Nutrition And Wound Healing
Author(s): Kazu Suzuki, DPM, CWS, and Zoe Birnbaum, BS Given that malnutrition and a loss of lean body mass can have an adverse effect on wound healing, clinicians should have a strong understanding of the impact of adequate protein intake and the pros and cons of different vitamin supplements. Accordingly, these authors offer a salient review of current guidelines and recommendations for facilitating optimal nutrition in patients with lower extremity wounds. We often say “You are what you eat” and nutrition is a vital component to healing chronic wounds. It is imperative that regular nutrition counseling be a part of your initial and ongoing assessment for patients with wounds. According to a study produced by Wissing and colleagues, patients who live by themselves (common in our elderly patients) are often malnourished as they may eat fewer meals or foods of lesser nutritional value.1 Clinicians may evaluate the nutrition of patients and their level of isolation through a series of standardized questionnaires (see “A Closer Look At The Nutritional Screening Initiative Checklist” at left and “A Guide To The Simplified Nutritional Appetite Questionnaire” below at right), or by interviewing patients as a part of the initial history taking. Clinicians play an influential role in nutrition intervention when a patient is susceptible to malnutrition, a condition that encompasses poor food selection or inappropriate caloric intake.1 Patients who lose lean body mass or protein mass due to injuries or infections can experience worsening wound conditions and a delay in healing.1 Consequently, evaluating and maintaining proper nutrition in patients with chronic wounds are imperative. Lean body mass accounts for approximately 75 percent of a healthy human’s body weig Continue reading >>
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- Evaluating Adherence to Dilated Eye Examination Recommendations Among Patients with Diabetes, Combined with Patient and Provider Perspectives