Novomix 30 (biphasic Insulin Aspart)
What is it used for? How does it work? NovoMix 30 pre-filled Flexpens and NovoMix 30 penfil cartridges (for use in Novopen devices) both contain biphasic insulin aspart. They are used to treat diabetes. People with diabetes have a deficiency or absence of a hormone manufactured by the pancreas called insulin. Insulin is the main hormone responsible for the control of sugar (glucose) in the blood. People with type 1 diabetes need to have injections of insulin to control the amount of glucose in their bloodstream. Insulin injections act as a replacement for natural insulin and allow people with diabetes to achieve normal blood glucose levels. The insulin works in the same way as natural insulin, by binding to insulin receptors on cells in the body. Insulin causes cells in the liver, muscle and fat tissue to increase their uptake of glucose form the bloodstream. It also decreases the production of glucose by the liver, and has various other effects that lower the amount of glucose in the blood. Novomix 30 contains a mix of two types of insulin, 30% soluble insulin aspart and 70% insulin aspart crystallised with protamine. This combination of insulins is called biphasic insulin aspart. Soluble insulin aspart is known as a rapidly-acting insulin. It works quickly, within 10 to 20 minutes, and its effects last for about three to five hours. Protamine-crystallised insulin aspart is known as intermediate-acting insulin. It takes longer to act, but its effects last much longer. The pre-mixed combination provides a rapid initial blood glucose lowering effect, followed by a prolonged effect that controls blood glucose throughout the day. It is usually injected under the skin immediately before or if necessary immediately after a meal. It is important to monitor your blood glucose Continue reading >>
How To Control Diabetes
Expert Reviewed Five Parts:Making a Diabetes Treatment Plan (Type 1 Diabetes)Making a Diabetes Treatment Plan (Type 2 Diabetes)Receiving Diabetes TestsManaging Your DietUsing MedicationCommunity Q&A For many, a diabetes diagnosis is a wake-up call. You can get a diagnosis at any age, and it's important to know what you can do to help yourself live a normal life with diabetes. Controlling a case of diabetes is usually a question of managing your blood sugar levels and living an active, health-conscious life. Medications (insulin for type 1 when the body can not make enough insulin, but often other medications for type 2, for when the body does not use its available insulin correctly) are also used to keep your blood sugar under control and to manage your symptoms. Getting your diabetes under control so you can live a happy and healthy life is the goal. The content in this article refers only to general cases and is not intended to replace the opinion of a doctor or following your medical team's advice. 1 Consult with a doctor to start or adjust your treatment plan. Type 1 diabetes, also called juvenile diabetes, is a chronic disease, which, despite its name, can begin and affect people at any age. This type of diabetes is an autoimmune disease. While it can occur suddenly due to infection, symptoms will usually appear after an illness.[1] Symptoms in type 1 are usually quite noticeable, more severe and quicker to cause illness. Symptoms for type 1 or advanced type 2 often include:[2] Increased thirst and frequent urination Dehydration Possibly extreme hunger with confused appetite (nothing satisfies you) Unexplained blurred vision Unexplained weight loss Unusual weakness/fatigue Irritability Slow-healing sores Frequent infections (such as gums or skin infections and vagi Continue reading >>
Metformin Overview
Metformin is a prescription medication used to treat type 2 diabetes. Metformin belongs to a group of drugs called biguanides, which work by helping your body respond better to the insulin it makes naturally, decreasing the amount of sugar your liver makes, and decreasing the amount of sugar your intestines absorb. This medication comes in tablet, extended-release tablet, and liquid forms. It is taken up to 3 times daily, depending on which form you are taking. Swallow extended-release tablets whole. Common side effects of metformin include diarrhea, nausea, and upset stomach. Metformin is a prescription medication used to treat type 2 diabetes. This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information. Metformin may be found in some form under the following brand names: Serious side effects have been reported including: Lactic Acidosis. In rare cases, metformin can cause a serious side effect called lactic acidosis. This is caused by a buildup of lactic acid in your blood. This build-up can cause serious damage. Lactic acidosis caused by metformin is rare and has occurred mostly in people whose kidneys were not working normally. Lactic acidosis has been reported in about one in 33,000 patients taking metformin over the course of a year. Although rare, if lactic acidosis does occur, it can be fatal in up to half the people who develop it. It is also important for your liver to be working normally when you take metformin. Your liver helps remove lactic acid from your blood. Make sure you tell your doctor before you use metformin if you have kidney or liver problems. You should also stop using metformin and call your doctor right away if you have signs of lactic acidosis. Lactic acidosis is a medical emergency that must be treate Continue reading >>
Are You A Skinny Fat Person? 10 Steps To Cure The Skinny Fat Syndrome
The common wisdom is that if you are overweight you are unhealthy, and if you are thin, you are healthy. But new research points to just how dangerous being skinny can be — if you are a “skinny fat” person, that is. The medical term for this is “MONW,” or metabolically obese normal weight, which I prefer to refer to as being a skinny fat person. It means you are under lean but over fat — not enough muscle and too much fat (especially belly fat). It seems it is better to be fat and fit than thin and out of shape. While we know that 68 percent of the American population is overweight, and that most have diabesity — being somewhere on the continuum of pre-diabetes to Type 2 diabetes — the shocking news from a study published in the Journal of the American Medical Association is that nearly 1 in 4 skinny people have pre-diabetes and are “metabolically obese.” What’s worse is that if you are a skinny fat person and get diagnosed with diabetes, you have twice the risk of death than if you are overweight when diagnosed with diabetes. Perhaps having that extra muscle on your body from having to carry around those extra pounds protects you. Studies on teenagers found that 37 percent of the skinny kids had one or more signs of pre-diabetes such as high blood pressure, high blood sugar, or high cholesterol. Wait — almost four out of 10 normal-weight kids are pre-diabetic? It is bad enough that one-third of kids are overweight or obese in America, but now it appears that only about 20 percent of children in America are healthy. In other words, 8 out of 10 children in America are overweight or have pre-diabetes or Type 2 diabetes. In my medical practice I see this all the time. Jim came in for a “wellness check up” and felt happy about his weight. His BMI Continue reading >>
Japi - Dipsi Guidelines
Abstract The Diabetes In Pregnancy Study group India (DIPSI) is reporting practice guidelines for GDM in the Indianenvironment. Due to high prevalence, screening is essential for all Indian pregnant women. DIPSI recommendsthat as a pregnant woman walks into the antenatal clinic in the fasting state, she has to be given a 75g oralglucose load and at 2 hrs a venous blood sample is collected for estimating plasma glucose. This one stepprocedure of challenging women with 75 gm glucose and diagnosing GDM is simple, economical and feasible.Screening is recommended between 24 and 28 weeks of gestation and the diagnostic criteria of ADA areapplicable. A team approach is ideal for managing women with GDM. The team would usually comprise anobstetrician, diabetes physician, a diabetes educator, dietitian, midwife and pediatrician. Intensive monitoring,diet and insulin is the corner stone of GDM management. Oral agents or analogues though used are stillcontroversial. Until there is evidence to absolutely prove that ignoring maternal hyperglycemia when thefetal growth patterns appear normal on the ultrasonogram, it is prudent to achieve and maintainnormoglycemia in every pregnancy complicated by gestational diabetes. The maternal health and fetal outcomedepends upon the care by the committed team of diabetologists, obstetricians and neonatologists. A shortterm intensive care gives a long term pay off in the primary prevention of obesity, IGT and diabetes in theoffspring, as the preventive medicine starts before birth. © INTRODUCTION The maternal metabolic adaptation is to maintain themean fasting plasma glucose of 74.5 ± 11 mg/dl andthe post prandial peak of 108.7 ± 16.9mg/dl.1 This fine tuning of glycemic level during pregnancy is possibledue to the compensatory hyperinsulinaemi Continue reading >>
Gad65 Autoantibodies And Its Role As Biomarker Of Type 1 Diabetes And Latent Autoimmune Diabetes In Adults (lada)
Go to: A. Introduction The plasticity of the interest in glutamic acid decarboxylase (GAD) across time is only matched by its relevance in human health and by the interest it continues to elicit as a tool to predict or possibly treat diabetes. It is difficult to conceive of another compound that has such critical biochemical relevance in a major pathway of neural physiology, whose genes are necessary for normal development, whose tissue distribution encompasses regulation of major parts of physiology in nerve function and metabolic regulation and also whose role as a self-antigen in T1D allows for the detection of at-risk populations and for the development of potential therapeutic approaches. 1. What is GAD? In basic biochemical terms, L-Glutamic acid decarboxylase is the major enzyme in the synthesis of g-amino butyric acid (GABA) which is a potent inhibitory neurotransmitter and a critical component of neurophysiologic function. It requires a co-factor, pyridoxal 5’-phosphate (i.e. (PLP or activated vitamin B6] to catalyze this reaction. GAD and GABA are mainly present in ‘GABA-ergic’ nerve cells but, interestingly, GAD/GABA are also detected in certain non-neural cells and organs such as the pancreas [1–3], where GABA is stored in synaptic-like vesicles in islet beta cells [4]. Although its functional relevance is presently unclear, it may be related to paracrine effects in the modulation of glucagon secretion in alpha cells [5]. It is noteworthy that the term GAD basically denotes an enzymatic activity that is part of a critical synthetic pathway. In terms of gene or protein structure and function, GAD involves two major protein isoforms that catalyze GABA synthesis. One isoform has a molecular size of 65kDa and is termed GAD65, while the second one, of 67k Continue reading >>
Type 3 Diabetes Attacks Your Brain?
Most of us have heard about type 1 or type 2 diabetes, but Type 3 diabetes barely puts a blip on the radar. Although discovered in 2005, this new condition is just beginning to pop up on the headlines of today’s science and medical news journals. Lay people still have a lot to learn. When it comes to type 3 diabetes, Wikipedia doesn’t even have the answers. The relatively new discovery of the disease leaves people concerned about their health searching for answers. Read on for a quick primer on diabetes mellitus 3 and how it may be affecting your health or the health of your loved ones. Type 3 Diabetes: What is it? During a study conducted at the Rhode Island Hospital and Brown Medical School, researchers made a groundbreaking discovery: the hormone insulin was not just produced by the pancreas as previously thought. After careful study of their subjects, the researchers discovered that the brain was also responsible to producing small amounts of insulin. This discovery led to several more important revelations. One of those revelations was the discovery of insulin’s effect on the brain. One of those effects on the brain is the development of diabetes mellitus 3. Type 3 diabetes is a condition where the brain does not produce enough insulin. In the absence of insulin, the brain is affected much the way the body is in type 1 or type 2 diabetes. In fact, diabetes mellitus 3 only occurs in people who have either type 1 or type 2 diabetes already. Type 3 Diabetes: Alzheimer’s in Disguise Diabetes mellitus 3 is also known as brain diabetes. This is because the brain requires insulin to form new memories. Receptors on the brain’s synapses help facilitate the communication that creates new memories. The insulin produced by the brain wards off amyloid beta-derived dif Continue reading >>
Diabetes Mellitus Cured - George's Experience
7 Long Wheat Mash Diet Regimen (LWMDR) 7.3 Duration required for diabetes cure If you are a Face book member & like this page, please login using the link above & mark your Like. If you are a Google user & feels like recommemding this to others, please click on the +1 link above & make the public recommendation. If you have anything to ask, tell or suggest about this page, please click this, land in the discussion page & key in it there. All watching users will get email alert about your edit and will certainly respond to it. Diabetes is considered a syndrome rather than a disease by modern medicine. It remains a companion to the grave - once diabetic always diabetic is the order of the day. Due to different reasons the Beta cells of Pancreas get impaired and adversely affects the quality or quantity or both of Insulin being produced in the body - partially in case of Type 2 & totally in case of Type 1 Diabetes. Due to the insufficiency or inefficiency of insulin produced by pancreas, blood sugar levels go up degrading strength & health of human body by starving all cells. Damaging vulnerable organs like Kidney & Heart makes diabetes fatal; whereas impairment of Retina of eye, cerebral haemorrhage/stroke, gangrene of foot/lower-leg etc make rest of life miserable. Diabetes is seen to be progressive, degenerative & incurable. This is because the cause (impairment of pancreas) is never treated; only its effect (blood sugar increase) is looked into and taken care of. The author hence left the beaten track when he was diagnosed diabetic & took a drastically different approach instead, based on the enlightenment imparted by an Aayurveeda exponent and his own exposure. He designed a diet based on Long Wheat Mash as the staple part & a life style appropriate to a diabetic. Wit Continue reading >>
Diabetes Mellitus
"Diabetes" redirects here. For other uses, see Diabetes (disambiguation). Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic disorders in which there are high blood sugar levels over a prolonged period.[7] Symptoms of high blood sugar include frequent urination, increased thirst, and increased hunger.[2] If left untreated, diabetes can cause many complications.[2] Acute complications can include diabetic ketoacidosis, hyperosmolar hyperglycemic state, or death.[3] Serious long-term complications include cardiovascular disease, stroke, chronic kidney disease, foot ulcers, and damage to the eyes.[2] Diabetes is due to either the pancreas not producing enough insulin or the cells of the body not responding properly to the insulin produced.[8] There are three main types of diabetes mellitus:[2] Type 1 DM results from the pancreas's failure to produce enough insulin.[2] This form was previously referred to as "insulin-dependent diabetes mellitus" (IDDM) or "juvenile diabetes".[2] The cause is unknown.[2] Type 2 DM begins with insulin resistance, a condition in which cells fail to respond to insulin properly.[2] As the disease progresses a lack of insulin may also develop.[9] This form was previously referred to as "non insulin-dependent diabetes mellitus" (NIDDM) or "adult-onset diabetes".[2] The most common cause is excessive body weight and insufficient exercise.[2] Gestational diabetes is the third main form, and occurs when pregnant women without a previous history of diabetes develop high blood sugar levels.[2] Prevention and treatment involve maintaining a healthy diet, regular physical exercise, a normal body weight, and avoiding use of tobacco.[2] Control of blood pressure and maintaining proper foot care are important for people with t Continue reading >>
A Clinical Study On The Effect Of Rishyagandha (withania Coagulans) In The Management Of Prameha (type Ii Diabetes Mellitus)
Go to: Introduction Ayurveda recognized, Prameha as a disease entity in distant past. Among several health problems Prameha, is considered as one of the arch enemy of the mankind. Prameha comprises a number of diseases with various physical and chemical changes in urine. The manifestation of the disease is described as “Prabhutavilmutrata,” which means frequent and copious urine with turbidity.[1,2] It is also believed that, if not cured or treated properly in due course of time, Prameha changes in Madhumeha, which is very similar to diabetes mellitus, the most debilitating disease.[3] Diabetes mellitus is a metabolic disorder characterized by polyurea, polydipsia, hyperglycemia, glycosuria, and generalized weakness may be associated with weight loss. This is the disease that affects every tissue and every organ of the body and is responsible for significant morbidity, reduced life expectancy, and diminished quality of life. It has been seen that there is no any organ or system spared from the diabetic complications, such as nephropathy, neuropathy, retinopathy, and so on. So there is a need for effective drugs for controlling Diabetes and preventing undesirable complications. Although the introduction of many oral hypoglycemic agents and insulin in modern medical science have great importance in the management of Diabetes, the hazardous effects of these drugs after long term use are incurable or proves many times fatal, hence an ideal therapy is still obscure. Ayurvedic management of Diabetes aims not only to achieve a euglycemic state but also to treat the root cause of disease. There are many medicinal plants mentioned in Ayurvedic texts, particularly in Nighantus having Pramehahara property. In the present work, the drug “Rishyagandha” (Withania coagulans) h Continue reading >>
- The UK Prospective Diabetes Study (UKPDS): clinical and therapeutic implications for type 2 diabetes
- The effect of insulin on bone mineral density among women with type 2 diabetes: a SWAN Pharmacoepidemiology study
- The interpretation and effect of a low-carbohydrate diet in the management of type 2 diabetes: a systematic review and meta-analysis of randomised controlled trials
Lychee | Litchi Fruit 13 Health Benefits And Fact | Side-effects
Lychee is sweet and a very fragrant fruit, which is usually available in the summer. This fruit originated in China, but today is found in most of the South East Asian countries. It is the member of soapberry family, Sapindaceae. There are three sub-species of Lychee. It has rough skin outside while contains juicy and creamy white flesh inside. Lychee has an incredible taste and in modern times, it has found its niche in dessert, juice and ice cream. Lychee is a small fruit packed with loads of healthy nutrients. It is considered an exotic fruit and has a very short shelf life. This is why it is available for a very limited time even during its season. In ancient China, lychee was the favored fruit in the imperial corridors finding its greatest fans among the Kings and Queens; who would get these beautiful fruits transported to capital at a significant cost to the Kingdom. See also: 45 Healthiest Fruit List On The Earth Lychee is a very nutritious fruit. It has a high water content and is full of energy. (1) Lychee has a high level of vitamin C in it and meets about 86% of the body’s daily requirement of this vitamin. It contains 15.23 gms sugar and has a reasonable 1.3 gms of dietary fiber. Lychees are a valuable source of Polyphenols that make it a reliable and highly recommended antioxidant. The composition of minerals makes it an excellent fuel for the electrolyte balance in our body. Due to its numerous health benefits lychee is used as an alternative medicine in China. It contains a healthy blend of nutrients that promote health. So, know the amazing health benefits of lychee that can make a lot of difference to your fitness in a tasty way. 1. Strengthens Immunity Vitamin C is a water-soluble Vitamin which means that it is not stored in the body. (2) Our bodily Continue reading >>
Gymnema
Conditions of Use and Important Information: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. This information may not fit your specific health circumstances. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Information from this source is evidence-based and objective, and without commercial influence. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. © Therapeutic Research Faculty 2009. Continue reading >>
Januvia Side Effects
What is Januvia? Januvia (sitagliptin) is an oral diabetes medicine that helps control blood sugar levels. It works by regulating the levels of insulin your body produces after eating. Januvia is for treating people with type 2 diabetes. Januvia is sometimes used in combination with other diabetes medications, but is not for treating type 1 diabetes. Important information You should not use Januvia if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin). Before taking this medicine You should not use Januvia if you are allergic to sitagliptin, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin). To make sure Januvia is safe for you, tell your doctor if you have ever had: kidney disease (or if you are on dialysis); heart problems; pancreatitis; high triglycerides (a type of fat in the blood); gallstones; or a history of alcoholism. Januvia is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Your name may need to be listed on a Januvia pregnancy registry when you start using this medicine. It is not known whether sitagliptin passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby. Januvia is not approved for use by anyone younger than 18 years old. How should I take Januvia? Take Januvia exactly as it was prescribed for you. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended. You may take Januvia with or without food. Follow your doctor's instructions. Your blood sugar will need to be checked often, and you may need othe Continue reading >>
Did You Know Insulin Plant ? Magic Cure For Diabetes
Costus Igneus, Insulin plant is a medicinal plant and capable of having Magic Cure for Diabetes. Leaf of this herbal plant helps to build up insulin by strengthening beta cells of Pancreas in the Human body thus popularly known as “Insulin plant” in India Plant name: Insulin Plant Botanical Name: Costus Igneus An insulin plant is a nature's gift for the people who are suffering from Diabetes. A leaf–a-day, keeps diabetes away is the famous saying about this plant. The leaves of this plant are used in treating diabetes as it helps to reduce your blood sugar level effectively in short period. Though the insulin plant was first grown in America, now the insulin leaves treatment on diabetes is highly effective in Indian medicinal therapies. This plant can be easily grown in the home nursery also. Diabetes is a disease of metabolism, where body is not able to synthesis sufficient insulin or the blood cells stop responding to the insulin produced in the body. The leaves of insulin plant contain mostly of Corosolic Acid which is beneficial in controlling diabetic. The corosolic acid present in the green leaves induces the insulin production and thus controls hyperglycemia in the blood. The leaves of insulin plant (Costus igeus) reduced the fasting and postprandial blood sugar levels, bringing them down towards normal. Note: This leaf is not recommended for pregnant or lactating women Please consult your doctor before use. Continue reading >>
10 Celebrities Living With Diabetes
Recently, actor Tom Hanks revealed that he was diagnosed with type 2 diabetes, a lifelong condition, which occurs when the body does not produce enough insulin. The 57-year-old has already been dealing with high blood pressure since the age of 36, reports contactmusic.com. Though the condition can be controlled through an effective diet, Hanks chooses to do otherwise. ‘Well it’s controllable through diet. My doctor said, ‘If you can weigh what you weighed in high school, you’ll essentially be completely healthy and not have Type 2 diabetes.’ And I said, ‘Well, I’m going to have Type 2 diabetes then’, he added. Tom Hanks is not the only celebrity suffering from diabetes. Here are some other celebrities who’ve tackled the menace: Sonam Kapoor Anil Kapoor’s daughter has struggled with diabetes from her teenage years. She has followed a strict diet regime with daily insulin to stay healthy. Her hectic schedule did take a toll on her but she soon learned to manage the condition, and hasn’t let it stop her from becoming one of the most sought-after actresses in B-town. (Read: Sonam Kapoor’s weight loss secrets) Halle Berry The Bond girl was diagnosed was diabetes when she was 23 after she fainted on a TV set. She was taken aback by the disease because none of her family members suffered from it. Since then, she has been taking daily insulin injections for the rest of her life and overhauled her diet. She now follows a diet that is low in fat, sugar, processed carbs and avoids all junk food or sweets. (Read: How celeb trainer Ramona Braganza got Jessica Alba and Halle Berry to shed their post pregnancy weight) Salma Hayek The curvy actress suffered from gestational diabetes (diabetes during pregnancy), which she claimed runs in her family. She told Amer Continue reading >>
