Fatigue
Fatigue affects an estimated 80% of all sarcoidosis patients, even when other symptoms are well controlled. For some, this symptom can be persistent and disabling, affecting their quality of life and ability to complete daily functions. If you suffer from fatigue, you are not alone. Some sarcoidosis patients are so debilitated by it that they are unable to work. Others are underemployed or feel unable to do activities they used to enjoy because of their symptoms. To make things worse, many patients are not taken seriously by family, friends, and healthcare providers because they appear to be healthy. FSR recognizes this to be a huge barrier to wellness that needs to be recognized and treated with the same compassion given to those who are battling visible illnesses. Luckily, this is an area of sarcoidosis which has been studied more thoroughly in recent years and there are steps you and your doctors can take to investigate and treat the symptoms. There are a couple considerations your doctor will take into account when assessing your fatigue: Is your disease currently under control? Patients who have active inflammation and associated organ dysfunction are likely to experience fatigue. This may result both from their disease and as a side effect to common treatments. Corticosteroids, for example, are a first line therapy for sarcoidosis whose side effects include weight gain, diabetes, and sleep apnea that can worsen fatigue. If your disease is not under control, it is important to first work with your doctor(s) to determine the best course of treatment to address the inflammation in your body. If you have just been diagnosed with sarcoidosis, you may benefit from finding a physician with familiarity with sarcoidosis in our searchable provider directory. We also suggest Continue reading >>
Fatigue In Women With Type 2 Diabetes
Fatigue is a widespread clinical complaint among adults with type 2 diabetes (T2DM),1–3 has been directly related to poor self-reported health,4 and is likely a key barrier to successful self-management of diabetes.5 Despite this, there are few data describing the magnitude, severity, or etiology of diabetes-related fatigue. This lack of research is surprising due to the number of physiological, psychological, and lifestyle factors that could predispose patients with T2DM to high levels of fatigue. It is perhaps easy to assume that fatigue in patients with T2DM is simply due to elevated blood glucose; however, this has not been substantiated in prior research. Furthermore, other contributing factors to fatigue in diabetes may warrant exploration. Physiological factors that could affect fatigue in T2DM include alterations in blood glucose levels or symptoms related to acute and/or chronic diabetes complications. Psychological factors include emotional distress stemming from diabetes self-management regimens or depression. Lifestyle factors may include increased body mass index (BMI) and reduced physical activity. For the purposes of the study, fatigue was defined as a subjective perception of a decreased capacity to perform physical and/or mental tasks due to one or a combination of physiological, psychological, or lifestyle phenomena, including altered glucose control, diabetes symptoms, diabetes emotional distress, depression, physical inactivity, and BMI.6 The purpose of this study was to explore the relationship between fatigue and physiological, psychological, and lifestyle phenomena in women with type 2 diabetes (T2DM), in order to establish the magnitude and correlates of fatigue in women with T2DM and explore the interrelationships between fatigue and specific Continue reading >>
Chronic Fatigue In Type 1 Diabetes: Highly Prevalent But Not Explained By Hyperglycemia Or Glucose Variability
OBJECTIVE Fatigue is a classical symptom of hyperglycemia, but the relationship between chronic fatigue and diabetes has not been systematically studied. We investigated prevalence, impact, and potential determinants of chronic fatigue in patients with type 1 diabetes mellitus (T1DM). RESEARCH DESIGN AND METHODS Out of 324 randomly selected T1DM outpatients, 214 participated in this cross-sectional observational study. Participants were compared with age- and sex-matched population-based controls. Chronic fatigue, functional impairments, current health status, comorbidity, diabetes-related factors, and fatigue-related cognitions and behaviors were assessed with questionnaires, and HbA1c values and comorbidity were assessed with medical records. Sixty-six patients underwent continuous glucose monitoring combined with an electronic fatigue diary for 5 days. Acute fatigue and four glucose parameters were determined: mean, variability, and relative time spent in hypoglycemia and hyperglycemia. RESULTS T1DM patients were significantly more often chronically fatigued (40%; 95% CI 34–47%) compared with matched controls (7%; 95% CI 3–10%; P < 0.001). Chronically fatigued patients had significantly more functional impairments. Fatigue was the most troublesome symptom. Age, depression, pain, sleeping problems, low self-efficacy concerning fatigue, and physical inactivity were significantly associated with chronic fatigue. Chronically fatigued patients spent slightly less time in hypoglycemia (proportion 0.07 ± 0.06 vs. 0.12 ± 0.10; P = 0.025). Glucose parameters were not related to acute fatigue. CONCLUSIONS Chronic fatigue is highly prevalent and clinically relevant in T1DM. Its significant relationship with cognitive behavioral variables and weak association with blood gl Continue reading >>
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- Association of Glycemic Variability in Type 1 Diabetes With Progression of Microvascular Outcomes in the Diabetes Control and Complications Trial
Diabetic Gastroparesis
Learn the connection between diabetes and tummy and bowel troubles. By the dLife Editors If you have diabetes, you may have noticed that your digestion isn’t quite what it used to be. The connection isn’t obvious, but diabetes can damage the nervous system in ways that show up in the form of stomach or bowel problems. It’s sometimes referred to as diabetic gastroparesis. What is gastroparesis? In gastroparesis, also called delayed gastric emptying, the stomach takes too long to empty its contents. Here’s how it works. The autonomic nervous system—the part of the nervous system that “automatically” regulates our internal organs while we go about our lives —controls the movement of food through the digestive tract. Normally, the vagus nerve, which controls the muscles of the stomach, tells the muscles to contract after a meal or snack to break up food and move it along to the small intestine. But if the vagus nerve is damaged, the muscles of the stomach don’t work normally, and the movement of food slows or even grinds to a halt. Diabetes is the most common known cause of gastroparesis. Type 1 and type 2 diabetes can damage the vagus nerve if blood glucose levels stay high for too long. How? High blood glucose causes chemical changes in nerves and damages the blood vessels that bring them much-needed oxygen and nutrients. While there’s no cure for gastroparesis, treatment can help manage the condition. What are the signs of gastroparesis? Signs and symptoms may be mild or severe and can include: heartburn nausea vomiting of undigested food an early feeling of fullness when eating weight loss abdominal bloating erratic blood glucose levels lack of appetite acid reflux spasms of the stomach wall erratic bowel movements Symptoms might be worse after eatin Continue reading >>
P-232 - The Comparison Of Fatigue Between Patients With Diabetes Melittus, Psychiatric Outpatients And General Population In Greece
Fatigue is of great clinical and investigational importance. It is a prevalent symptom in general population and a central symptom in many diseases, for example, cancer, ischaemic heart disease and depression. Besides, it's a side effect of many medical treatments. Fatigue has been shown to have a substantial impact on patients’ self care activities and, overall quality of life. Objectives To compare levels of the various aspects of fatigue in three different populations. We conducted a survey in a random sample of 69 patients with diabetes Mellitus (DM), 114 psychiatric outpatients (PO) and 383 healthy adults (C), using the Multidimensional Fatigue Inventory (MFI-20). ANOVA test was used to reveille the statistical significance between the groups in all levels of fatigue. Results The control group had a significant difference to the PO and DM patients in physical fatigue (MDPO = -3.835 p < .001), (MDDM. = -2.745p< .001), in reduced activity (MD PO = -3.719 p < .001), (MDDM = -3.155 p < .001) and reduced motivation (MDPO = -3.569 p < .001), (MDDM = -2.349 p < .001). Psychiatric outpatients had a significant difference with DM patients and control in general fatigue (MDC = -4.135 p< .001), (MDDM. = -3.835 p < .001) and in mental fatigue (MDC = 4.638 p < .001), (MDDM. = 4.346 p < .001). Analysis shows that both psychiatric outpatients and patients with DM experience fatigue in all aspects of the measurement as expected, in a statistical significant level compared to the general population. Continue reading >>
Help For Diabetes Fatigue
Diabetes fatigue can stop you in your tracks. The good news: You can get back your get-up-and-go today. These days, Mary L. wakes up refreshed. But a few years ago, she began feeling constantly tired, regardless of how much she rested. “I could fall asleep with kids screaming in the background,” recalls the 62-year-old grandmother, who was diagnosed with type 2 diabetes 25 years ago. Mary was battling diabetes fatigue, a condition most people with the disease face at some point. What causes the exhaustion and brain fog varies, says Tami Ross, RD, LD, CDE, president-elect of the American Association of Diabetes Educators. “People describe the fatigue as wading through molasses—they are so tired they don’t want to do anything. The trick is to find out what’s slowing you down and take steps to get energized again.” Energy sapper: out-of-control blood sugar Whether your blood sugar is too high or low, sluggishness and lethargy can result. Energy booster: start fresh If you’ve had diabetes for a while, you might have let your good habits lapse. To renew your commitment to your diabetes-management plan, pretend you’ve just been diagnosed: See your diabetes educator to review the basics and seek out the latest findings. It worked for Mary: “Acting like I was a novice made me feel enthusiastic and encouraged about taking control again.” Energy sapper: stress A little bit of stress can help you spring into action, but too much can drag you down by spiking your blood sugar levels and making your heart work harder. Energy booster: talk slowly When you feel your tension rise, make a conscious effort to speak more slowly than usual. It sends a message to your brain to calm down and lets others know that you are in control of the situation. It also buys you time Continue reading >>
Fatigue And Cognitive Symptoms In Patients With Diabetes: Relationship With Disease Phenotype And Insulin Treatment
Summary Neurobehavioral symptoms are frequently reported in patients with diabetes. Nevertheless, the characterization of the specific symptom dimensions that develop in diabetic patients with respect to disease phenotype and treatment status remains obscure. This study comparatively assessed fatigue symptoms and cognitive performance using a dimensional approach in 21 patients with insulin-treated type 1 diabetes, 24 type 2 diabetic patients either insulin-free or undergoing insulin treatment for at least six months, and 15 healthy subjects. Specific dimensions of fatigue were assessed using the Multidimensional-Fatigue-Inventory (MFI). Cognitive performance on tests of choice reaction time, pattern recognition memory and spatial planning was evaluated using the Cambridge-Neuropsychological-Automated-Battery (CANTAB). Body mass index (BMI) and glycated-hemoglobin (HbA1C) concentrations were collected, as well as information on diabetes complications and disease duration. Patients with type 2 diabetes, regardless of insulin treatment status, exhibited higher scores of fatigue, primarily in the dimensions of general and physical fatigue as well as reduced activity. Cognitive alterations, in the form of longer reaction times and impaired spatial planning, were also detected in type 2 diabetic patients treated with insulin. These alterations were overall unrelated to glucose control, as reflected in HbA1C levels, and were not explained by complications and duration of diabetes. No specific alteration was measured in type 1 diabetic patients who exhibited fatigue scores and cognitive performance comparable to healthy participants. While associated with fatigue, increased BMI did not significantly account for the relationship of type 2 diabetes with general fatigue and physi Continue reading >>
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Fatigue In Adults With Type 2 Diabetes – An Overview Of Current Understanding And Management Approaches
Patients with type 2 diabetes commonly experience fatigue, which may be incapacitating and adversely affect self-care regimens.,sup>1–7 Fatigue is a perplexing problem for healthcare providers.8 Wessely suggests that because fatigue is a non-specific and universal symptom, chronic fatigue is challenging to diagnose and treat.9 Fatigue researchers do not have a standardised definition, measurement approach, or diagnostic criteria. Diabetes-related fatigue is assumed to correlate with alterations in glucose homeostasis, but few data support this hypothesis.3,7,10,11 Fatigue in type 2 diabetes may be is associated with higher body mass index (BMI),1,7,12 the presence of co-morbid conditions,7,13 depression,7 physical inactivity,1,7,14 sleep disturbances1,15,16 and elevated cytokines.3,10 Fritschi and Quinn recently provided a detailed review of the correlates of fatigue in diabetes, including conflicting findings regarding the relationship between fatigue and glycaemic control.8 Type 2 diabetes is a disorder associated with chronic low-grade inflammation.17,18 Type 2 diabetes and insulin resistance, especially among obese patients, were linked to an increased production of pro-inflammatory cytokines (e.g., tumour necrosis factor alpha [TNF-α], monocyte chemoattractant protein-1 [MCP-1], interleukin-1β [IL-1β], interleukin-6 [IL-6]) from immune cells as well as increased acute phase reactants (e.g., C-reactive protein [CRP]). Pro-inflammatory cytokines and CRP were associated with high fatigue levels10,11,19,20 and depression and sleep disturbances in a variety of diseases.21–24 There is a considerable gap in the literature, however, about the treatment of fatigue secondary to type 2 diabetes. Anti-inflammatory therapies may ameliorate fatigue with type 2 diabetes. T Continue reading >>
Prediabetes
What Is Prediabetes? Prediabetes is a “pre-diagnosis” of diabetes—you can think of it as a warning sign. It’s when your blood glucose level (blood sugar level) is higher than normal, but it’s not high enough to be considered diabetes. Prediabetes is an indication that you could develop type 2 diabetes if you don’t make some lifestyle changes. But here's the good news: . Eating healthy food, losing weight and staying at a healthy weight, and being physically active can help you bring your blood glucose level back into the normal range. Diabetes develops very gradually, so when you’re in the prediabetes stage—when your blood glucose level is higher than it should be—you may not have any symptoms at all. You may, however, notice that: you’re hungrier than normal you’re losing weight, despite eating more you’re thirstier than normal you have to go to the bathroom more frequently you’re more tired than usual All of those are typical symptoms associated with diabetes, so if you’re in the early stages of diabetes, you may notice them. Prediabetes develops when your body begins to have trouble using the hormone insulin. Insulin is necessary to transport glucose—what your body uses for energy—into the cells via the bloodstream. In pre-diabetes, your body either doesn’t make enough insulin or it doesn’t use it well (that’s called insulin resistance). If you don’t have enough insulin or if you’re insulin resistant, you can build up too much glucose in your blood, leading to a higher-than-normal blood glucose level and perhaps prediabetes. Researchers aren’t sure what exactly causes the insulin process to go awry in some people. There are several risk factors, though, that make it more likely that you’ll develop pre-diabetes. These are Continue reading >>
Factors Affecting Fatigue In Patients With Type Ii Diabetes Mellitus In Korea
Summary This study aimed to characterize and identify the factors affecting fatigue in patients with type II diabetes mellitus in Korea. A total of 180 patients with type II diabetes mellitus were recruited from the outpatient clinic of a tertiary care hospital. For data collection, a questionnaire survey of diabetes history, hypoglycemia symptoms, and fatigue was conducted between January and February 2011. Data were analyzed using t test, analysis of variance, Pearson's correlation, and hierarchical multiple regression. The mean fatigue and hypoglycemia symptom scores of patients with type II diabetes mellitus were 2.88 ± 0.61 and 6.18 ± 12.60, respectively. Hypoglycemia symptoms (p = .004), disease duration (p < .001), and age (p < .001) correlated positively with fatigue. Hierarchical multiple regression analysis revealed that hypoglycemia symptoms was the variable positively influencing fatigue in patients with type II diabetes mellitus after adjustment for influences of demographic and clinical characteristic variables. Hypoglycemia symptoms were confirmed to be a predictor of fatigue. Consequently, it is essential to consider age, and disease duration as well as hypoglycemia symptoms to intervene fatigue effectively among patients with type II diabetes mellitus. Continue reading >>
Symptoms Of Reactive Hypoglycemia And Insulin Resistance
Being plagued by excessive fatigue is bad enough, but problems with blood sugar regulation can also lead to even scarier downstream issues including heart disease, stroke, cancer, dementia, and more. Feeling sleepy all the time and being chronically fatigued are classic reactive hypoglycemia and insulin resistance symptoms. The standard American diet, high in simple sugars and processed foods, is notorious for causing problems with blood sugar regulation. In the short term, eating a meal loaded with sugar and refined carbs (like white flour) can cause you to experience wild swings in blood sugar. These large blood sugar swings make you feel tired, anxious, irritable, and hungry for more quickly absorbed sugars. Feeling sleepy all the time and experiencing these other symptoms of blood sugar dysregulation after a high-carb meal is not normal, nor is it healthy. These are the classic signs of what is known as reactive hypoglycemia and they may be insulin resistance symptoms, which is more serious and could be an early warning sign of diabetes down the road according to the medical journal, Current Opinion in Endocrinology, Diabetes and Obesity.[1] So how are sugars and sweets linked to the problem of feeling sleepy all the time along with reactive hypoglycemia and insulin resistance symptoms? Eating this way carries with it a “high glycemic load,” meaning it contains high amounts of the kind of carbohydrates which quickly release their sugars into the bloodstream. High-glycemic-load diets have been shown in human studies to lead to feeling sleepy all the time, daytime fatigue, poorer sleep, and slower cognitive performance.[2,3] In the long term, eating a diet full of empty calories, refined carbohydrates (bread, pasta, rice, potatoes), sugars, and sweetened beverages Continue reading >>
Cognitive Behavioral Therapy To Treat Fatigue In Type I Diabetes Patients
Fatigue (both physical and mental) is prevalent in type I diabetes patients, with approximately 40% of patients scoring higher on fatigue scales than the general population. A recent study published in the Lancet Diabetes-endocrinology evaluates the efficacy cognitive behavioral therapy (CBT) to reduce fatigue in type I diabetes patients. Several studies have shown that cognitive behavioral therapy (CBT) can help ameliorate fatigue symptoms. CBT is based on a model which assumes that fatigue is triggered by disease-specific elements, such as hyperglycemia in the case of type I diabetes, and maintained by cognitive-behavioral elements. Based on these assumptions, a diabetes-specific CBT intervention was developed and delivered as a combination of face-to-face and web-based sessions. Previously, no study had addressed CBT intervention for fatigue in type I diabetes patients. Parameters such as glycemic control and functional impairment were also evaluated. Between 2014-2016, 120 patients from medical and university centers in the Netherlands were randomly assigned to a treatment (n=60) or waiting list control (n=60) group. Eligible participants included patients, aged 18-70, who had been diagnosed with type 1 diabetes for at least 1 year, were able to speak/read/write Dutch, scored 35 or higher on the fatigue scale (ranges from 8-56) and had chronic fatigue defined as lasting 6 months or more. Patients with severe diabetes complications such as renal failure, blindness and heart failure were ineligible. All study participants were provided with study information and voluntarily signed an informed consent form. The treatment group received 5 months of CBT delivered by clinical psychologists trained in fatigue therapy for type 1 diabetes (named Dia-Fit). Patients assigned t Continue reading >>
Symptoms, Diagnosis & Monitoring Of Diabetes
According to the latest American Heart Association's Heart Disease and Stroke Statistics, about 8 million people 18 years and older in the United States have type 2 diabetes and do not know it. Often type 1 diabetes remains undiagnosed until symptoms become severe and hospitalization is required. Left untreated, diabetes can cause a number of health complications. That's why it's so important to both know what warning signs to look for and to see a health care provider regularly for routine wellness screenings. Symptoms In incidences of prediabetes, there are no symptoms. People may not be aware that they have type 1 or type 2 diabetes because they have no symptoms or because the symptoms are so mild that they go unnoticed for quite some time. However, some individuals do experience warning signs, so it's important to be familiar with them. Prediabetes Type 1 Diabetes Type 2 Diabetes No symptoms Increased or extreme thirst Increased thirst Increased appetite Increased appetite Increased fatigue Fatigue Increased or frequent urination Increased urination, especially at night Unusual weight loss Weight loss Blurred vision Blurred vision Fruity odor or breath Sores that do not heal In some cases, no symptoms In some cases, no symptoms If you have any of these symptoms, see your health care provider right away. Diabetes can only be diagnosed by your healthcare provider. Who should be tested for prediabetes and diabetes? The U.S. Department of Health and Human Services recommends that you should be tested if you are: If your blood glucose levels are in normal range, testing should be done about every three years. If you have prediabetes, you should be checked for diabetes every one to two years after diagnosis. Tests for Diagnosing Prediabetes and Diabetes There are three ty Continue reading >>
Chronic Fatigue Syndrome: Symptoms, Treatment, And Causes
Chronic fatigue syndrome (CFS or ME/CFS) is a condition of prolonged and severe tiredness or weariness. It is not relieved by rest and is not directly caused by other conditions. CFS is a syndrome of persistent incapacitating weakness or fatigue, accompanied by nonspecific symptoms, that lasts at least 6 months, and not attributable to any known cause. To be diagnosed with this condition, tiredness must be severe enough to decrease an individual's ability to participate in ordinary activities by 50 percent. Chronic fatigue syndrome is much more than just feeling tired often. People with CFS are so run down that it interferes with their lives and can make it hard to function at all. Literature on the condition dates back to the 1700s. Through the centuries, it's been falsely attributed to various causes and is only now beginning to be better understood. Fast facts on CFS: People with CFS have trouble staying on top of their responsibilities at home and on the job. Others are severely disabled and even bedridden. Symptoms of CFS include ones similar to common viral infections, including muscle aches, headache, and fatigue. CFS occurs most often in people aged 40-50, more often in women than men, and is less prevalent among children and adolescents. What are the symptoms of chronic fatigue syndrome? People with CFS are dealing with extreme fatigue, but also a wide range of other symptoms, including flu-like symptoms and chronic pain. When referring to chronic fatigue syndrome, patients, and patient advocates often prefer to call the condition chronic fatigue and immune dysfunction syndrome (CFIDS) to convey the complexity of the illness. Symptoms of chronic fatigue syndrome come on within a few hours or days, last for 6 months or more, and can include: headaches tender lym Continue reading >>
Diabetes Fatigue And Other Symptoms (and Treatment For Them)
This guide was designed mainly for people coming to terms with their diabetes symptoms as they accept that they have the disease or that the disease is progressing. We cover exactly the implications of each side-effect, focusing on the side-effects that are less commonly questioned but still present. If you desire, skip down to the various sections of symptoms you’re dealing with to learn more. Before we get started, here are some of the diabetes treatment programs we’ve tried and seen good success with as far as reducing/eliminating symptoms goes. Recommended Diabetes Treatments 1. The Diabetes Destroyer (ebook/pdf) This is a very detailed guide to getting diabetes under control, aimed at both Type 1 and Type 2 diabetics. It was created by David Andrews and I personally found it to be extremely informative and instructional as far as getting blood sugar levels back under control, as well as increasing energy and making diabetes overall easier to manage. It also helps you construct a diabetic diet and lifestyle to try and aleviate diabetes symptoms as best as you can naturally. The official website, which features a video presentation for more information, is 2. Metformin (oral pill) This is a pretty common diabetes medications that can be easy enough to pick up from your doctor. It’s designed to help control your blood sugar levels. I’ve found that this was pretty effective, but the probably is that it’s a medicine so like all medicines, eventually you run out. Being too dependent on Metformin can lead to you falling into a pitfall as far as your money goes, depending entirely on medications to try and get your symptoms under control instead of giving natural methods a solid chance. 3. The ADA Diet The ADA diet was created by the American Diabetes Association Continue reading >>
