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Diabetes Is Actually Five Separate Diseases, Research Suggests

Diabetes Is Actually Five Separate Diseases, Research Suggests

Diabetes is actually five separate diseases, research suggests By James Gallagher Health and science correspondent, BBC News These are external links and will open in a new window Image caption Could there be five types of diabetes rather than just two? Scientists say diabetes is five separate diseases, and treatment could be tailored to each form. Diabetes - or uncontrolled blood sugar levels - is normally split into type 1 and type 2. But researchers in Sweden and Finland think the more complicated picture they have uncovered will usher in an era of personalised medicine for diabetes. Experts said the study was a herald of the future of diabetes care but changes to treatment would not be immediate. Diabetes affects about one in 11 adults worldwide and increases the risk of heart attack, stroke, blindness, kidney failure and limb amputation. Type 1 diabetes is a disease of the immune system, which affects around 10% of people with the condition in the UK. It errantly attacks the body's insulin factories (beta-cells) so there is not enough of the hormone to control blood sugar levels. Type 2 diabetes is largely seen as a disease of poor lifestyle as body fat can affect the way the insulin works. The study, by Lund University Diabetes Centre in Sweden and the Institute for Molecular Medicine Finland, looked at 14,775 patients including a detailed analysis of their blood. The results, published in The Lancet Diabetes and Endocrinology , showed the patients could be separated into five distinct clusters. Cluster 1 - severe autoimmune diabetes is broadly the same as the classical type 1 - it hit people when they were young, seemingly healthy and an immune disease left them unable to produce insulin Cluster 2 - severe insulin-deficient diabetes patients initially looked ver Continue reading >>

Experts Explain How Personalised Diabetes Treatments Can Help Patients

Experts Explain How Personalised Diabetes Treatments Can Help Patients

Experts explain how personalised diabetes treatments can help patients Improving diagnosis and further understanding the role of genes in diabetes risk can pave the way for more personalised treatments, say researchers. Dr Ines Cebola, postdoctoral researcher at Imperial College London, and Dr Shivani Misra, consultant in metabolic medicine at Imperial College Healthcare NHS Trust, presented their research on type 2 and rare diabetes, as well as personalised treatments at the recent Imperial College Academic Health Science Centre (AHSC) seminar series. In a packed lecture theatre at St Marys Hospital, Dr Cebola explained how variations in non-coding sections of the genome might contribute to type 2-diabetes risk in the video above. Type 2 diabetes is a common conditionthat causes the level of glucose in the blood to become too high. It can cause symptoms like excessive thirst and tiredness.It can also increase the risk of developing more serious conditions connected to the heart, eyes and nerves. It affects over 400 million people worldwide and genetic factors have long been known to have an important role in determining a persons risk of type 2 diabetes, alongside other factors such as body weight, diet and age. Dr Cebola explained how scientists at the College have mapped the regions in the genome that orchestrate gene activity in the cells of the pancreas that produce insulin, a hormone that regulates blood sugar. In type 2 diabetes, the tissues become less responsive to insulin, resulting in blood sugar levels being too high. Most people can compensate when this happens by producing more insulin, but in people with type 2 diabetes, the pancreas cannot cope with this increased demand. The team also identified genome sequences that drive gene activity in insulin-prod Continue reading >>

Diabetes Experts Believe Overweight People Could Hold Key To Tackling Disease | Health | Life & Style | Express.co.uk

Diabetes Experts Believe Overweight People Could Hold Key To Tackling Disease | Health | Life & Style | Express.co.uk

Overweight people whose stem cells stored fat more efficiently had a lower risk of diabetes Dr Wael Kafienah, from Bristols School of Cellular and Molecular Medicine, said there had been a lot of interest in people who weighed more than would normally be considered healthy but did not have any health problems. He said: The existence of obese individuals with lower risk of diabetes has received great interest in the past few years, as they may hold the clue to understanding and possibly treating obesity-associated diabetes. Our clinical data confirmed the previously reported variability in obesity-associated pathology. Diabetes is a common life-long health condition. There are 3.5 million people diagnosed with diabetes in the UK and an estimated 500,000 who are living undiagnosed with the condition. People should be aware signs and symptoms of diabetes are not always obvious and the condition is often diagnosed during GP check ups. Here, we have shown that the group with healthy fat stem cells had lower cholesterol and a better liver function. However, the report concerns fat stem cells alone and is not about peoples actual diets. A source close to the study said: This isnt about people being able to eat what they like. Continue reading >>

Diabetes Clinics | Diabetes Uk

Diabetes Clinics | Diabetes Uk

Diabetes clinics give you the chance to meet medical experts who can check that you're well and give you highly specialised advice on how to look after your diabetes here's how they work. If so much of your diabetes care is up to you, why go to a diabetes clinic? One reason is to help you understand new things. Clinic staff have years of experience specialising in helping people with diabetes. It's the kind of expertise you're unlikely to find in a GP or practice nurse who deals in general healthcare. Clinic staff check how your diabetes is being managed, help you with any difficulties, and pre-empt any possible future health problems. You know what your blood test results are every day, but if you've had a really bad patch, it's hard to get things in perspective. Clinic staff will show you how well you are doing over a longer period. After your first visit, you'll probably go back on a regular basis usually about four times a year. Every year you'll have a big checkup to look you over completely. Every time you go, clinic staff should also give you the results of any tests and explain them to you. These results will help you with your diabetes control. If you're not given the results, or don't understand them, ask and keep asking if needs be. Depending on your age, you'll probably go to the clinic with a parent or guardian. But there might be parts of your clinic visit that you want them to come to, and other parts when you want to be alone. Don't be afraid to ask for this if you want it clinic staff will understand. When you move on to an adult clinic this can be quite different from a child or adolescent clinic. You should be offered a clinic where the children and adult teams work together and monitor your diabetes. Continue reading >>

Diabetes Research | Our Goals And Strategy | Diabetes Uk

Diabetes Research | Our Goals And Strategy | Diabetes Uk

Diabetes UK funds research in three ways: We award money to support new ideas proposed by UK researchers. We fund personal awards to help talented scientists and healthcare professionals become the diabetes research leaders of the future. We make targeted investments to support research in specific areas where there are important gaps or opportunities. In each case, our rigorous approach ensures that Diabetes UK funded research is of the highest scientific quality, has the greatest potential to benefit people living with diabetes and offers value-for-money to our supporters. Our approach is also flexible, to help us respond to new opportunities as they arise. Every year we evaluate the progress and impact of our work and report the findings in our annual report. We offer support to scientists and healthcare professionals working at universities and hospitals throughout the UK. Our funding pays for salaries as well as the equipment and materials needed to carry out diabetes research. Researchers request our support by completing an application form through our online portal. Each application is assessed (or peer reviewed) by independent experts from around the world, who consider the feasibility, cost-effectiveness and likely success of the proposed research. Each reviewer must be a senior researcher and have expertise in an area relevant to the application. To make sure this process is fair and impartial, we do not accept reviews where there are conflicts of interest, such as where an applicant and reviewer have worked together in the recent past. In addition to independent experts, each application is considered by our Grants Advisory Panel of people living with diabetes, who decide which applications are the highest priority for people with the condition. Twice a yea Continue reading >>

Label Food Risks Say Experts As Diabetes Soars

Label Food Risks Say Experts As Diabetes Soars

Label food risks say experts as diabetes soars Label food risks say experts as diabetes soars ALL food products and restaurant menus should carry compulsory traffic-light labelling to combat Type 2 diabetes, experts say. It would assist the public in making healthier choices and arrest an epidemic that threatens to cripple the NHS, says Diabetes UK. Two-thirds of adults and a third of primary schoolchildren are overweight or obese. Yesterday Helen Dickens, from the charity, said: We know people with diabetes want more information but whats interesting is better labelling influences spending habits as a whole. The public has an appetite to see better information about the food theyre buying. Its not just good for the health of the public, its good for business as well. Its time for Government to act and take this simple, bold step. Diabetes UK found six in 10 Britons would be more likely to buy food with traffic-light labelling on menus and packaging. Diabetes: Five breakfast snacks to slash blood sugar Fifty-seven per cent said they would be more likely to buy food from a reduced-calorie range. Traffic-light labelling shows if the food has high (red), medium (amber) or low (green)amounts of fat, saturated fat, sugars and salt. TV chefs Jamie Oliver and Hugh Fearnley-Whittingstall are among those who have demanded a sterner approach to tackling childhood obesity. There is already a sugar tax on some soft drinks but the duo suggest it should be extended to milkshake drinks. Better labelling on restaurant menus could create a much healthier diet for much of the population Campaigners also say added sugar should be given in teaspoons not grams and advertising sugary drinks should be banned. In Type 2 diabetes the pancreas fails to produce enough insulin or the cells do not Continue reading >>

Leicester Professors Named In The Top 10 Diabetes Experts Globally

Leicester Professors Named In The Top 10 Diabetes Experts Globally

Leicester Professors named in the top 10 diabetes experts globally Posted by ap507 at Jun 11, 2015 04:50 PM | Permalink Professors Kamlesh Khunti and Melanie Davies named in Expertscape list Professor Kamlesh Khunti and Professor Melanie Davies (pictured) havebeen named in the top 10 diabetes experts globallyon alist published at the American Diabetes Association meeting in Boston, USA this week. The data are compiled by Expertscape using a matrix based on nearly 100,000 articles published since 2005. The Leicester Diabetes Centre, a leading Centre in diabetes research and education, is led by Professor Kamlesh Khunti and Professor Melanie Davies from the University of Leicester and Leicesters Hospitals. The Leicester Diabetes Centre is an alliance between the University Hospitals of Leicester NHS Trust (Leicesters Hospitals), the University of Leicester, the local community and Primary Care and is located at Leicester General Hospital. Professor Khunti said: This was a real surprise to us but we are absolutely honored to be recognised in this list of some of the top researchers in the world. This is recognition of the work being conducted by our Leicester Diabetes Team from the University of Leicester over the past 15 years. Professor Davies said: This is great news for Leicester and recognises the impact that our research on diabetes is having internationally." Continue reading >>

List Of Every Expert Witness Claiming Expertise In Diabetes

List Of Every Expert Witness Claiming Expertise In Diabetes

We have learnt the lessons from the mistakes of others, now you can learn them too! Slip one in your bag, and you can be the expert with the facts at your fingertips! List of every expert witness claiming expertise in Diabetes This list shows every expert witness in the UK Register of Expert Witnesses who claims expertise in Diabetes. Click on any expert witness to view full details. You may prefer to interactively search the Register . Paediatric nephrology Congenital & structural abnormalities to the urinary tract Urinary tract infection Nephrotic syndrome Acute renal failure Acute glomerulonephritis Chronic renal failure Dialysis, peritoneal & haemodialysis Transplantation Metabolic diseases affecting the kidney Haemolytic uraemic syndrome Neonatal renal failure Honorary Reader in Paediatric Neurology McCollum Consultants is a unique collaboration of medico-legal experts offering medico-legal advice in the following disciplines: Anaesthesia Cancer & Oncology (all aspects) Cardiology Diabetes & the Diabetic Foot General Surgery (all aspects) Haematology Musculoskeletal Radiology Neuroanaesthesia Neurology & Stroke Medicine Nursing Podiatric Surgery Rehabilitation Medicine Respiratory & Lung ... I have been a full-time NHS general practitioner since 2009 I teach trainee GPs & I also appraise other GPs I am a tutor of medical students at University College London My work covers traditional general practice in a surgery, urgent care centres & out-of-hours I write on average 50 reports a year in the field of clinical negligence in general practice I can usually complete a report within 2 weeks Several solicitors have agreed to act as references: please feel free to ask me for their details ... All aspects of ophthalmology, injury & disease affecting the eyes & eye surger Continue reading >>

Diabetes - London Medical

Diabetes - London Medical

London Medical started over 25 years ago as a specialist diabetes clinic, and today we remain at the very forefront in the field; the UK's leading private provider of head-to-toe diabetes care. London Medical began lifeas a Diabetes Clinic, and has been the preferred provider for thousands of patients for more than 25 years.It specialises in the support and management of all types of diabetes for adults and children. Our vision is simple: comprehensive diagnostic and therapeutic excellence in one centre. This vision can be seen through the clinic; theexperienced Consultants, Dietitians, and Specialist Nurses, the state-of-the-art facilities for the assessment and treatment of diabetic eye disease, cardiovascular health, impotence, nerve damage and kidney disease. Were passionate about improving blood sugar control and abolishing hypoglycaemia. With these objectives, we encourage our patientsto learn from our carbohydrate counting courses, and use wireless advanced technology to help improve control and delay complications. We carefor both the physical and psychological aspects associated with diabetes through a multidisciplinary team approach who each believe in a holistic approach to patient care, and in the benefits of education and support. Screening for MODY, a rare genetic form of diabetes Preventative management for pre-diabetes, including weight management and exercise counselling Advice on blood glucose meters and use of downloading analysis Continuous Glucose Monitoring Medtronic, Navigator and Dexcom Education on carbohydrate counting and management of diabetes Podiatrist and access to orthotics, for foot ulcer management 24-hour ambulatory blood pressure monitoring, by miniature radial artery tonometry, including cASP Carotid intima media study and lower lim Continue reading >>

Choosing To Have Your Treatment At Uclh

Choosing To Have Your Treatment At Uclh

We know that coping with diabetes isnt always easy. But were here to help you. Were part of a teaching hospital with state-of-the-art facilities and an award-winning team consisting of specialist doctors, nurses, psychologists and dietitians. Our nationally-recognised service helps children and young people (up to 19 years) with type 1 diabetes, type 2 diabetes, maturity onset diabetes in the young and secondary diabetes (with steroid therapy). We support children with multiple daily insulin injections. We are a centre for insulin pump therapy (a more flexible alternative to injections for some). We run a childrens clinic, adolescent clinic, transition clinics and intensive therapy sessions. We have an adolescent ward for young people struggling with diabetes. We provide integrated specialist psychological support to all young people. Above all, were here to deliver a high quality and responsive diabetes service that maximises health and wellbeing for children, young people and families. So its little wonder that were the top diabetes service in the country (National Paediatric Diabetes Audit 2011-2012). But we cant do it without your help the role of both parents and patients is vital. Our long term aim is to encourage and support you as an expert diabetes carer. Continue reading >>

Diabetes Diagnoses Have More Than Doubled In 20 Years, Uk Analysis Suggests

Diabetes Diagnoses Have More Than Doubled In 20 Years, Uk Analysis Suggests

Diabetes diagnoses have more than doubled in 20 years, UK analysis suggests Diagnoses of all diabetes types have shot up since 1998, says Diabetes UK as it calls for greater efforts to lower risk of type 2 Last modified on Mon 26 Feb 2018 19.50EST Diagnosis of both type 1 and type 2 diabetes has increased, but the rise has been greater for type 2, which some experts link to higher obesity rates.Photograph: Alfsky/Getty Images The number of adults and older teens with diabetes in the UK has more than doubled over the past 20 years, with 3.7 million people aged 17 or older now known to be living with the disease, campaigners say. A new analysis, compiled by the charity Diabetes UK, appears to show that the number of diagnoses has shot up since 1998, at which point it is estimated 1.8 million over 16s were diagnosed with diabetes. 'The hardest thing is waking up and part of your body has gone' The analysis does not break down figures into the two main forms of diabetes, type 1 and type 2. But Nikki Joule, policy manager at Diabetes UK, said that other research had shown diagnoses of both have increased, but the rise has been greater for type 2. [The] rise in obesity has driven that largely over recent years, she said. While both types of diabetes are linked to genetics, type 1 diabetes is not associated with weight but is an autoimmune condition where insulin is not produced. It normally begins in childhood and accounts for about 10% of diabetes cases. Type 2 diabetes where little insulin is produced, or insulin does not trigger an uptake of glucose by the bodys cells is linked to obesity , and typically starts later in life, with about 60% of cases thought to be preventable . Both types bring with them the risk of complications such as blindness, stroke, cardiovascular d Continue reading >>

Experts Set For Diabetes Uk Conference

Experts Set For Diabetes Uk Conference

Education, Good practice Latest news Research More than 2,800 experts in the field of diabetes are expected to attend a conference focused on all aspects of the condition next week. The three-day Diabetes UK Professional Conference , which takes place at Glasgows SECC , will start on Wednesday, March 2. The conference attracts attendees from a wide range of backgrounds, including basic orclinical scientists, healthcare professionals, representatives of charitable or voluntary organisations, pharmaceutical representative and medical students. Programme highlights will include a variety of leading speakers and plenary sessions onnew outcome trials in type 1 and type 2 diabetes. The prestigious Diabetes UK Named Lectures and Rank Nutrition Lecture will be delivered by leading academics who have been nominated by colleagues and elected by the Diabetes UK Healthcare Professional Groups. On Friday thehot topic sessions will featureresearch news from the diabetes clinics around the world. There will also be a stand-alone workshop track across all three days of the conference which will provide hands-on training and structured education from leading experts, including psychosocial and allaspects of diabetes care. Calum Sutherland, the chair of the Professional Conference Organising Committee and reader at the University of Dundee, said: In essence there should be something exciting for every diabetes-associated professional discipline, a truly not-to-be-missed occasion for those who care about improving care and preventing future diabetes. Continue reading >>

Diabetes Experts Confident They Can Wipe Out Killer Disease In 25 Years

Diabetes Experts Confident They Can Wipe Out Killer Disease In 25 Years

UK teams are leading the race against a disease which will hit 6.25 million people by 2035 – 10 per cent of the population – and already costs the NHS £1million an hour. In an exclusive interview, Britain’s most respected diabetes researcher said he was confident the insulin-deficiency disease would be wiped out by the time he retires in 25 years. Dr Nick Oliver, diabetes consultant at Imperial College Healthcare NHS Trust, said: “There is a race on, that’s why what we are doing is incredibly exciting.” Asked whether the disease could ever be cured he added: “I really hope so. I am reasonably early in my career and there is lots of really exciting work going on behind the scenes. “There are lots of avenues that will lead to potential cures for Type 1 and Type 2 diabetes and if I could see it in my career that would be incredibly exciting.” He added: “Diabetes can’t be cured at the moment. The race is on to get effective treatments for people. Their quality of life is important.” Dr Alasdair Rankin, director of research for Diabetes UK, said: “We think it is possible we could have a vaccine for Type 1 within 20 years.” Diabetes can’t be cured at the moment. The race is on to get effective treatments for people. Their quality of life is important Human trials have already started on the world’s first artificial pancreas, created by 39-year-old Dr Oliver’s team. It would offer sufferers of Type 1 diabetes, an auto immune disease, the most effective treatment available. The Bio-Inspired Artificial Pancreas – BiAP – is attached to the abdomen via a thin tube. It reads sugar levels and sends information to an insulin pump which releases the hormone around the clock. This eliminates painful daily blood tests and injections. One researcher Continue reading >>

Type 1 Diabetes | London Diabetes Centre :london Diabetes Centre

Type 1 Diabetes | London Diabetes Centre :london Diabetes Centre

Currently affecting as many as 40 million people worldwide, this is by far the less common of the two main types of diabetes. It was thought to occur predominantly in children and young people but is now known to occur later in life as well. With modern care, the latest drugs and technology, living with type 1 diabetes is easier today than it has ever been. Type 1 diabetes is an auto-immune condition where the body mistakenly attacks its own insulin-producing beta cells resulting in an insulin deficiency. The main symptoms include increased thirst, weight loss and frequent urination. No one knows yet why this type of diabetes is so variable among different groups of people and in different countries, or why its steadily on the rise. There may be a genetic susceptibility in some populations, and some believe that environmental factors like toxins, viruses or early diet could be partly to blame. Maintaining normal glucose levels with varying eating habits Type 1 diabetes is treated with insulin injections. And with modern care, including the use of sensor technology, we can now achieve good glucose levels without hypoglycaemia (i.e. low blood sugar). We use the latest insulins, pumps and drugs to prevent weight gain, which can be a real problem for some patients. A zero tolerance approach to low blood sugar The negative effects of hypoglycaemia on quality of life, sleep, and on the heart are now increasingly appreciated, which is why we now aim for zero tolerance to hypoglycaemia. Always at the cutting edge of diabetes care We know that diabetes care and the use of new technology and treatments is moving fast; we are often the first diabetes clinic in the UK to trial new, potentially life enhancing innovations to assess them for our patients. We aim to be right at the cu Continue reading >>

Diabetes Uk | Grovelands Medical Centre

Diabetes Uk | Grovelands Medical Centre

701 Oxford Road, Reading, Berkshire, RG30 1HG Telephone: 0118 958 2525 | Fax: 0118 952 3633 We are the UKs leading diabetes charity. We care for, connect with and campaign alongside and on behalf of all people affected by and at risk of diabetes. We provide information, advice and support to help people with diabetes manage the condition well, and bring people together for support when its needed most. We influence governments, opinion formers, healthcare professionals and health services to ensure that people with diabetes get the standards of care they deserve. We are the UKs largest charitable funders of diabetes research and search relentlessly for life-changing breakthroughs that improve diabetes care, treatment and prevention. We are members and regular donors, trust and corporate supporters, runners, swimmers, mountain climbers, bakers and more raising vital funds to help fund our work. We are an army of nearly 7,000 individuals and over 250 groups raising awareness, raising funds and making the work of Diabetes UK possible. Together with our network of over 10,000 professional members and diabetes specialists, we share knowledge to improve the lives of people with diabetes. Continue reading >>

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