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Diabetes And Periodontal Disease Slideshare

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Influence Of Systemic Conditions On The Periodontium

Endocrine diseases such as diabetes and hormonal fluctuations,that are associated with puberty and pregnancy are well known examples of systemic conditions that adversally affect the condition of the periodontium. Endocrine disturbances and hormonal fluctuations affect the periodontal tissue directly,modify the tissue response to local factors and produce anatomic changes in the gingiva that may favor the plaque accumulation and disease progression. DIABETES MELLITUS Diabetes mellitus is an extremely important disease from a periodontal standpoint. It is complex metabolic disorder characterized by chronic hyperglycemia. Diminished insulin production,impaired insulin action or a combination of both result in the inability of glucose to be transported from the bloodstream into the tissues,which in turn results in high blood glucose levels and excretion of sugar in the urine. Lipid and protein metabolism is altered in diabetes as well. Uncontrolled diabetes(chronic hyperglycemia) is associated with several long term complications,including Microvascular diseases(retinopathy,nephropathy,neuropathy). Macrovascular diseases(cardiovascular,cerebrovascular). Increased susceptibility to inf Continue reading >>

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Popular Questions

  1. jwags

    Maximum dose of metformin

    I've hear different posters talk about different maximum doses of metformin. I'm currently taking 3 x 850. So that is 2550 mg. I hear some talk about 1500 or 2500. Is it that above that is dangerous or not effective. I test often to check for lows. I've never been below 93, usually in the upper 90's and low 100's. Are there any symptoms I should be watching out for. I've been on the new dose for a month, now and it has really changed my bg profile. I do think that the new dose of met along with a pretty low carb diet is working. I am finally seeing fasting in the 100's, just getting a little DP not the 40 or 50 point jump I was getting. I am also starting to lose weight again. I'm now only 2 1/2 pounds away from my goal of 125. I hear a lot of T 2's getting fasting numbers in the 80's, I guess that is my next goal.

  2. pookie

    i was told anything above 2500 is not effective. If you don't respond to 2500mg, you wouldn't respond to it anymore if you take more.
    Jeanne, what's your timing for your meds? are you spreading them out?
    I am taking 2000mg of Metformin (1000 X 2, morning/night) but it's not very effective on me. My doctor wanted to start me on another meds, but i am resisting, trying to control it with diet and exercise. I am not sure if i should increase it by 500mg and see if that will help.

  3. jwags

    I experimented with different times. The most effective is that I take 1 850 when I wake up (6), another around 12-1 pm and the last 850 around 11 pm. The big difference I notice is my late morning and afternoon numbers. I use to spike late morning and late afternoon. So my before dinner numbers were always high to start with ( 160). Now I'm staying in a tight range. This morning I ate around 9 am and tested around 11 am- 104, waited 2 hours for lunch (I guess it was too long because I was 122 before lunch), I made some blueberry whey-flax pancakes and bacon. I tested 2 hours later and I was 99. So taking that mid day really works for me. You might see if you can get the 850 tablets and take 3, or try taking 3 500 mg first to see if that changes your numbers. My doctor wanted me to try other additional meds and I resisted to. I'm not sure what I need to do to get my numbers to that 80 range, or if that is impossible without insulin.

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