Assessment Of Two-way Relationship Between Periodontal Disease And Gestational Diabetes Mellitus: A Case-control Study
Background: Gestational diabetes mellitus (GDM) is glucose intolerance which begins during pregnancy. Few studies have examined the association between periodontal disease and GDM. Aim: The aim of this study was to assess the association between periodontal disease and GDM. Materials and Methods: The study population comprised ninety patients, out of which thirty were cases and sixty were controls. All cases underwent a laboratory screening test for GDM between 24 and 30 weeks of gestation based on the recommendation of the obstetricians and gynecologists. To assess the periodontal status, a full-mouth periodontal examination assessing the probing depth, periodontal depth, bleeding on probing, clinical attachment level, and gingival recession was performed on all study participants by a single trained examiner. Tests for associations were performed using Chi-square statistics and multivariate logistic regression analysis. Results: None of the periodontitis conditions was found to be a significant predictor of GDM. In GDM patients, 70% of females were having periodontal disease whereas non-GDM patients 77% of patient had periodontal disease. Conclusion: The present study did not show any positive association between periodontal disease and GDM. Keywords: Gestational diabetes mellitus, periodontal disease, pregnancy How to cite this article: Kalra M, Tangade P, Punia H, Gupta V, Sharma H, Jain A. Assessment of two-way relationship between periodontal disease and gestational diabetes mellitus: A case-control study. Indian J Dent Res 2016;27:392-6 In the life-course of a female, an important milestone is a pregnancy with the dual factors of oral health affecting the pregnancy outcome and pregnancy affecting oral health. Pregnant women are more prone to common chronic oral d Continue reading >>
- Women in India with Gestational Diabetes Mellitus Strategy (WINGS): Methodology and development of model of care for gestational diabetes mellitus (WINGS 4)
- Is there a relationship between vitamin D with insulin resistance and diabetes mellitus?
- Periodontal Disease Linked with Diabetes and Heart Health
Diabetes And Periodontal Disease ,at Two Way Relationship
1. Diabetes and Periodontal disease A two way relationship 2. Contents • Diabetes overview • Periodontal disease overview • Relation between Diabetes and Periodontal disease • effect of diabetes on periodontal disease and its mechanism • Effect of periodontal disease on diabetes and its mechanism • references 3. Introduction • Its widely thought that any diseases associated with each other , then one caused the other . • But many of these diseases interrelationship mechanisms is obscure ! • A better understanding of this relationship provides more appropriate treatment for these patients. • So in this seminar we will figure out the relation between diabetes and periodontal disease and its bidirectional mechanisms. 4. Diabetes Among many systemic diseases , diabetes ,have been a nightmare to researches ,doctors and patients , due to its difficult control and diverse complications 5. Classification according to its patho- physiology DM Type I IDDM due to destruction of beta cells of pancreas Type II NIDDM due to insulin resistance Gestational temporary condition occurs during pregnancy others Drug- or chemical- induced Diseases of the exocrine pancreas Genetic defects in *β-cell function, *insulin action 6. • Actually to understand diabetes its as simple as just increase in glucose in blood , whether its due to insulin deficiency or resistance. • But what will result from this increase ? Why is it dangerous then ? 7. • Deficiency of insulin secretion or insulin resistance , results in : Inability to transport glucose into cells Glucose retained in the blood stream Hyperglycemia Complications 8. • microangiopathy • nephropathy • neuropathy, • macro vascular disease • delayed wound healing. - All the forms of DM are associated with hyper Continue reading >>
Gum Disease & Diabetes: “a Two-way Relationship”
We’ve known for a long time that diabetes and gum disease often occur together. Now new research continues to show just how strong that association is. For instance, one recent study of more than 300 dental patients found that those with gum disease were more likely to have type 2 diabetes than those who had healthy mouths. The more advanced the disease, the greater the likelihood. In addition, according to the American Diabetes Association (ADA) guidelines for diagnosis, there was a significant over-representation of subjects with suspected diabetes (23% and 14%) and pre-diabetes (47% and 46%) in the severe periodontitis group and mild/moderate periodontitis groups, respectively, compared with the control group…. Notably, 18.1% of patients with suspected new diabetes were found among subjects with severe periodontitis compared with 9.9% and 8.5% among subjects with mild/moderate periodontitis and controls, respectively. Because of this, the authors suggest that the dental office is “a suitable location for screening for (pre)diabetes.” Why should these two conditions happen so often together? The mechanisms that underpin the links between these two conditions are not completely understood, but involve aspects of immune functioning, neutrophil activity, and cytokine biology. There is emerging evidence to support the existence of a two-way relationship between diabetes and periodontitis, with diabetes increasing the risk for periodontitis, and periodontal inflammation negatively affecting glycaemic control. Recent research in Cell Host & Microbe suggests that one factor may be changes in the composition of bacteria that live in the mouth. Those changes that the research team observed made the oral microbiome more apt to cause disease. The result was more inflamma Continue reading >>
Diabetes And Periodontal Disease: A Two-way Relationship
Journal of PEARLDENT Year : 2017, Volume : 8, Issue : 2 First page : ( 1) Last page : ( 15) Print ISSN : 0976-0180. Online ISSN : 2229-4457. Article DOI : 10.5958/2229-4457.2017.00005.8 Dr Singh Baljeet1, Dr Gandhi Naureen2,*, Dr Grover Deepak3 1Professor & HOD, Bhojia dental college & Hsp, Bhud (Baddi), H.P. 2pg student, Bhojia dental college & Hsp, Bhud (Baddi), H.P. 3Reader, National dental college and hospital, DeraBassi *Address for Corresspondance:-Dr. Naureen Gandhi Pg student, Bhojia dental college & Hsp, Bhud (Baddi), H.P. Abstract Periodontitis is an inflammatory disease of the supporting tissues of the teeth caused by specific micro-organisms or group of specific micro-organisms, resulting in progressive destruction of the periodontal ligament and alveolar bone with pocket formation, recession or both.1 Periodontal infections can adversely affect the systemic health with manifestations such as coronary heart disease, stroke, diabetes, preterm labor, low-birth weight delivery, and respiratory disease.1 Severe periodontitis often coexists with diabetes and is considered to be the sixth complication of the disease, as both type 1 and type 2 diabetic patients show a three-to four fold increased risk of periodontitis. 2 Diabetes mellitus is a metabolic disease characterized by dysregulation of carbohydrate, protein, and lipid metabolism. The primary feature of this disorder is elevation of blood glucose levels (hyperglycemia), resulting from either a defect in insulin secretion from the pancreas, a change in insulin action, or both.2 Uncontrolled diabetes (chronic hyperglycemia) is associated with several long-term complications, including microvascular diseases (retinopathy, nephropathy, neuropathy, etc.), macrovascular diseases (cardiovascular, cerebrovascular), Continue reading >>
Periodontitis And Diabetes: A Two-way Relationship
Go to: Abstract Periodontitis is a common chronic inflammatory disease characterised by destruction of the supporting structures of the teeth (the periodontal ligament and alveolar bone). It is highly prevalent (severe periodontitis affects 10–15% of adults) and has multiple negative impacts on quality of life. Epidemiological data confirm that diabetes is a major risk factor for periodontitis; susceptibility to periodontitis is increased by approximately threefold in people with diabetes. There is a clear relationship between degree of hyperglycaemia and severity of periodontitis. The mechanisms that underpin the links between these two conditions are not completely understood, but involve aspects of immune functioning, neutrophil activity, and cytokine biology. There is emerging evidence to support the existence of a two-way relationship between diabetes and periodontitis, with diabetes increasing the risk for periodontitis, and periodontal inflammation negatively affecting glycaemic control. Incidences of macroalbuminuria and end-stage renal disease are increased twofold and threefold, respectively, in diabetic individuals who also have severe periodontitis compared to diabetic individuals without severe periodontitis. Furthermore, the risk of cardiorenal mortality (ischaemic heart disease and diabetic nephropathy combined) is three times higher in diabetic people with severe periodontitis than in diabetic people without severe periodontitis. Treatment of periodontitis is associated with HbA1c reductions of approximately 0.4%. Oral and periodontal health should be promoted as integral components of diabetes management. Keywords: Diabetes, Diabetes complications, Periodontal diseases, Periodontitis, Type 1 diabetes mellitus, Type 2 diabetes mellitus Periodontitis (r Continue reading >>
Diabetes & Gum Disease A Two Way Street
Diabetes & Gum Disease A Two Way Street Diabetes, which kills more people annually than breast cancer and AIDS, can weaken your mouths ability to fight germs, increase blood sugar levels, and can make gum disease more severe and harder to control. When diabetes is poorly controlled, high glucose levels in mouth fluids may help germs grow and set the stage for gum disease. These bugs sit below the gum line and act as termites, eating away at your bone. But tooth loss is not the only consequence of gum disease. New research has shown this link to diabetes as well as heart disease, stroke, pneumonia, and even increased risk for problems related to pregnancy. The relationship between serious gum disease and diabetes is two-way. Not only are people with diabetes more susceptible to serious gum disease, but serious gum disease may have the potential to affect blood glucose control and contribute to the progression of diabetes. Smoking increases the risk for gum disease. If you are a smoker with diabetes, age 45 or older, you are 20 times more likely than a person without these risk factors to get severe gum disease, bone loss and tooth loss. Imagine life without gum disease. Without gum disease, you can live longer, increase the quality of life, keep your natural teeth, taste food better, prevent other oral diseases, infections and cavities, and have increased salivary function. Other symptoms such as poor wound healing, pain in the tongue and burning mouth can also be decreased by controlling gum disease. Proper dental treatment and maintaining your healthy teeth and gums makes living life free of gum disease easy! Use good oral hygiene. Brush your teeth after each meal and floss daily. Using a tongue scraper will also help to rid bacteria. To help prevent or control gum di Continue reading >>
Periodontitis And Diabetes Mellitus-a Two Way Relationship
Dr. Sneha Kothari*, Dr. Viral Patel**, Dr. Anita Panchal***, Dr. Hardik Mehta****, Dr. Bhaumik Nanavati*****. Abstract Periodontal disease (PD) and diabetes mellitus (DM) hold a consistent relationship. DM not only increases the risk of having PD and with that its prevalence, but it also augments the progression of more aggressive and quickly defining signs. There is a bidirectional relationship between DM and PD. The treatment of periodontitis in diabetic patients favors a reduction in mediators responsible for the destruction of periodontal tissue and decreases with it, resistance to insulin. PD is characterized by low grade chronic inflammation that may remain silent in diabetics causing damage that is not locally limited but may extend systemically. Our aim of this article is to make aware, both general dental and medical practioner about interrelationship between periodontal disease and diabetes with special emphasis on importance of mutual consultation between the two fraternity, which in turn significantly contributes to general well being of an individual. [Kothari S et al NJIRM 2013; 4(5) : 94-101] Key words: Periodontal Disease, Diabetes Mellitus, Poor Glycemic Control, AGE’s, Inflammation Continue reading >>
Diabetes And Periodontal Disease: A Two-way Relationship
Diabetes and Periodontal Disease: A Two-Way Relationship Diabetes and periodontal disease arevery destructive conditions that can eventually lead to tooth loss. This is because advanced periodontitis (advanced gum disease) destroys gum tissues before progressing to destroy the connective tissues holding your teeth in their sockets and the bone that actually forms these sockets ( dental alveolus ). With this amount of destruction, its hardly a surprise to learn that relationship between diabetes and periodontal disease is the major cause of tooth lossin the world. Preventing tooth loss is probably the main reason why people want to maintain healthy and strong gums, but diabetes and periodontal disease are also an inflammatory conditions that can have a serious impact on your general health. One disease it is frequently linked to is diabetes. Data from the National Diabetes Statistics Report which was released in June 2014 shows that in 2012, 9.3% of the American population had diabetes, while the percentage of Americans aged 65 or older with this disease was 25.9%. Its estimated that many more millions of Americans have undiagnosed diabetes and periodontal disease. The Connection between Diabetes and Periodontal Disease Diabetes and periodontal disease both are inflammatory conditions and diabetes reduces the bodys ability to fight infection. This does mean that diabetics are more susceptible towards developing periodontal disease, particularly if their condition is poorly controlled. If you are already diabetic, then developing periodontal disease can cause this condition to worsen. When diabetes and periodontal disease arentproperly controlled, it can increase the amount of glucose in saliva which provides the perfect fuel for disease-causing bacteria in the mouth. Th Continue reading >>
Diabetes And Periodontal Disease
Diabetic patients are more likely to develop periodontal disease, which in turn can increase blood sugar and diabetic complications. People with diabetes are more likely to have periodontal disease than people without diabetes, probably because people with diabetes are more susceptible to contracting infections. In fact, periodontal disease is often considered a complication of diabetes. Those people who don't have their diabetes under control are especially at risk. Research has suggested that the relationship between diabetes and periodontal disease goes both ways - periodontal disease may make it more difficult for people who have diabetes to control their blood sugar. Severe periodontal disease can increase blood sugar, contributing to increased periods of time when the body functions with a high blood sugar. This puts people with diabetes at increased risk for diabetic complications. Continue reading >>
Diabetes And Periodontal Disease: A Two Way Relation A Commentary
Diabetes and periodontal disease: a two way relation a commentary Department of Periodontics Pushpagiri College of Dental Sciences Thiruvalla, Kerala, India. An association between diabetes and periodontitis has been long suspected and has now been reasonably well documented for both type I insulin dependent diabetes mellitus and type II non insulin dependent diabetes mellitus. Diabetes mellitus is a systemic complication affecting both the quality and length of life. The inter-relationship between periodontitis and diabetes provides an example of systemic disease predisposing to oral infection and once the infection is established, the oral infection can exacerbate the systemic disease. Diabetes induced changes in immune functions which provide an inflammatory cell phenotype. This predisposes to chronic inflammation, progressive tissue break down and diminished tissue repair capacity. Periodontal tissues frequently manifest these changes because they are constantly wounded by substances emanating from bacterial bio films. The well informed dentist has the opportunity to be at the forefront of diagnosing diabetes. Studies have shown that non-surgical periodontal treatment is associated with improved glycemic control in type II diabetes mellitus patient. Periodontal treatment should be undertaken along with standard measures for diabetic control and care. Prevention and control of periodontal disease must be considered an integral part of diabetes mellitus. JACOB, G.. Diabetes and periodontal disease: a two way relation a commentary.ANNALS OF DENTISTRY (ADUM), [S.l.], v. 20, n. 1, p. 27-30, june 2013.ISSN 0128-7532. Available at: < >. Date accessed: 23 apr. 2018.doi: . Continue reading >>
- Periodontal Disease Linked with Diabetes and Heart Health
- Relation of total sugars, fructose and sucrose with incident type 2 diabetes: a systematic review and meta-analysis of prospective cohort studies
- Influence of uncontrolled diabetes mellitus on periodontal tissues during orthodontic tooth movement: a systematic review of animal studies
An Error Occurred Setting Your User Cookie
An Error Occurred Setting Your User Cookie This site uses cookies to improve performance. If your browser does not accept cookies, you cannot view this site. There are many reasons why a cookie could not be set correctly. Below are the most common reasons: You have cookies disabled in your browser. You need to reset your browser to accept cookies or to ask you if you want to accept cookies. Your browser asks you whether you want to accept cookies and you declined. To accept cookies from this site, use the Back button and accept the cookie. Your browser does not support cookies. Try a different browser if you suspect this. The date on your computer is in the past. If your computer's clock shows a date before 1 Jan 1970, the browser will automatically forget the cookie. To fix this, set the correct time and date on your computer. You have installed an application that monitors or blocks cookies from being set. You must disable the application while logging in or check with your system administrator. This site uses cookies to improve performance by remembering that you are logged in when you go from page to page. To provide access without cookies would require the site to create a new session for every page you visit, which slows the system down to an unacceptable level. This site stores nothing other than an automatically generated session ID in the cookie; no other information is captured. In general, only the information that you provide, or the choices you make while visiting a web site, can be stored in a cookie. For example, the site cannot determine your email name unless you choose to type it. Allowing a website to create a cookie does not give that or any other site access to the rest of your computer, and only the site that created the cookie can read it. Continue reading >>
Periodontal Disease And Diabetes
ABSTRACT Background The association between diabetes and inflammatory periodontal diseases has been studied extensively for more than 50 years. The author reviews the bidirectional relationships between diabetes and periodontal diseases. Conclusions A large evidence base suggests that diabetes is associated with an increased prevalence, extent and severity of gingivitis and periodontitis. Furthermore, numerous mechanisms have been elucidated to explain the impact of diabetes on the periodontium. While inflammation plays an obvious role in periodontal diseases, evidence in the medical literature also supports the role of inflammation as a major component in the pathogenesis of diabetes and diabetic complications. Research suggests that, as an infectious process with a prominent inflammatory component, periodontal disease can adversely affect the metabolic control of diabetes. Conversely, treatment of periodontal disease and reduction of oral inflammation may have a positive effect on the diabetic condition, although evidence for this remains somewhat equivocal. Clinical Implications Patients with diabetes who have periodontal disease have two chronic conditions, each of which may affect the other, and both of which require frequent professional evaluations, in-depth patient education and consistent educational reinforcement by health care providers. Continue reading >>
Periodontitis And Diabetes: A Two-way Relationship
Abstract Periodontitis is a common chronic inflammatory disease characterised by destruction of the supporting structures of the teeth (the periodontal ligament and alveolar bone). It is highly prevalent (severe periodontitis affects 10-15% of adults) and has multiple negative impacts on quality of life. Epidemiological data confirm that diabetes is a major risk factor for periodontitis; susceptibility to periodontitis is increased by approximately threefold in people with diabetes. There is a clear relationship between degree of hyperglycaemia and severity of periodontitis. The mechanisms that underpin the links between these two conditions are not completely understood, but involve aspects of immune functioning, neutrophil activity, and cytokine biology. There is emerging evidence to support the existence of a two-way relationship between diabetes and periodontitis, with diabetes increasing the risk for periodontitis, and periodontal inflammation negatively affecting glycaemic control. Incidences of macroalbuminuria and end-stage renal disease are increased twofold and threefold, respectively, in diabetic individuals who also have severe periodontitis compared to diabetic individuals without severe periodontitis. Furthermore, the risk of cardiorenal mortality (ischaemic heart disease and diabetic nephropathy combined) is three times higher in diabetic people with severe periodontitis than in diabetic people without severe periodontitis. Treatment of periodontitis is associated with HbA(1c) reductions of approximately 0.4%. Oral and periodontal health should be promoted as integral components of diabetes management. Discover the world's research 14+ million members 100+ million publications 700k+ research projects Join for free Periodontitis and diabetes: a two-way rel Continue reading >>
Diabetes Mellitus And Periodontal Disease: Unravelling The Two Way Relationship
Manikandan GR, Ajithkumar KC Department of Periodontics, Government Dental College, Trivandrum* Corresponding Author: Dr Manikandan GR, Junior Resident, Department of Periodontics, Government Dental College, Trivandrum. E-mail: [email protected] ABSTRACT Diabetes and chronic periodontitis are common chronic diseases affecting adults in all population groups. Periodontitis is the second common cause of dental disorder. Diabetes mellitus affects a high segment of adults especially in later life. Periodontitis is the sixth common cause of disease in Diabetes patients. This article examines the interrelationship between these common diseases. INTRODUCTION Diabetes mellitus and chronic periodontitis are common chronic diseases in adults in the world population. Periodontal disease is chronic inflammatory disease of the tissues that support and attach the teeth to the jaws.1 They are caused by gram-negative bacterial infections and are, for the most part, asymptomatic, although much of the actual destructive tissue changes observed clinically are result of the inflammatory host response. Periodontal disease is the second main cause of oral cavity disorders affecting the population due to its high prevalence.2 Diabetes mellitus is a complex disease with both metabolic and vascular components, characterized by hyperglycemia due to defects in insulin secretion, insulin action or both.3 Persons with diabetes mellitus are at greater risk of developing periodontal diseases. Periodontal disease is now considered the sixth complication of diabetes mellitus.4 Not only is it more prevalent in this population, but also the progression of symptoms, in a more aggressive and more rapidly setting mode. The main reasons for this situation are the scarce information on the importance of o Continue reading >>
Diabetes And Periodontitis: A Two Way Relationship
Piero Policicchio* CEO, Air Force Inc. Holland, MI, USA. Visit for more related articles at Research & Reviews: Journal of Dental Sciences Abstract Periodontitis is a destructive inflammatory disease of the supporting tissues of the teeth and is caused by specific microorganisms or group of specific microorganisms resulting in progressive destruction of periodontal ligament and alveolar bone with periodontal pocket formation, gingival recession or both. The link between periodontal disease and systemic diseases has been progressively recognized over the past two decades. Currently there is a large amount of data in epidemiological, clinical and laboratory studies that strongly correlate the role of periodontal pathogens on systemic organs by producing pro-inflammatory cytokines, chemokines and inflammatory mediators. Although the relationship between periodontal disease, inflammation and overall health has been suspected, numerous studies are providing more comprehensive evidence for this link. In this context, diabetes predisposes oral tissues to greater periodontal destruction but several studies have now identified that periodontal disease leads to poor glycemic control. It was hence predicted that there exists a two-way relationship between periodontal disease and diabetes mellitus. The regular use of Dental Air Force home dental cleaning system as an oral hygiene device is optimal for suppressing both periodontal infection and associated systemic diseases (Diabetes) as compared to conventional tooth brushing. Keywords Periodontitis, Diabetes, HbA1c, CRP Periodontitis: A Microbial Infection The oral cavity has the potential to harbor at least 600 different bacterial species, and in any given patient, more than 150 species may be present, surfaces of tooth can have a Continue reading >>
