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Diabetes And Hypertension Pathophysiology

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Pathophysiology Of Diabetic Nephropathy

Diabetic nephropathy is a devastating chronic microvascular diabetic complication, which represents the major cause of end stage renal failure today. The mechanisms leading to the development and progression of this most feared diabetic complication are mainly poor metabolic and haemodynamic control. We should direct all our efforts into achieving good glycaemic and blood pressure control. Prevention of diabetic nephropathy is our only tool to beat this disease currently. The prevention and management of diabetes and its renal complication is a huge global challenge: the global number of diabetic patients is believed to be around 180 million and is set to increase to 350-400 million in the next two decades. Patients with type 2 diabetes will account for 90% of all cases, and we expect an increase of new cases of diabetic nephropathy (DN) within the current decade, given the predicted 30-40% prevalence of renal disease in the diabetic population. The concomitant increase in associated cardiovascular mortality and morbidity (nearly 40 times higher in patients with nephropathy than in patients without nephropathy), and end stage renal disease (ESRD) will result in significant social a Continue reading >>

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  1. loulan

    66


    Diabetes prevalence by country [1800x940] (i.redd.it)
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  2. HolyGigi

    Is this type 2 or type 1? Totally different diseases.

  3. Ovejas

    I'm guessing type 2, as it is much more common. Considering the numbers type 1 would be way too high.

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