Central Diabetes Insipidus Vs Nephrogenic Diabetes Insipidus

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Video describes types of neurogenic bladder or neurogenic incontinence.The video describes the types of neurogenic incontinence. For similar educational videos in Neurology, please download the app Neuroppt from android and apple store. For iphone users link is https://itunes.apple.com/us/app/neuro... For android users the link is- https://play.google.com/store/apps/de... Or log-on to www.neurovishal.com

Neurogenic Vs. Nephrogenic Diabetesinsipidus

What is the difference between nephrogenic and neurogenic diabetes insipidus? Nephrogenic diabetes insipidus is from the word nephro meaning kidneys. This indicates that the cause of the increase in urine output is due to a problem in the kidney. In diabetes insipidus, more than 2.5 liters of urine is excreted per day. The excretion of urine is controlled by the amount of anti-diuretic hormone (ADH) released from the hypothalamus. In nephrogenic DI, the level of ADH in the body is normal to high. ADH levels may rise in order for the body to compensate the increased excretion of water, but because the kidneys are damaged, response to ADH stimulation is diminished. The diminished response of the kidneys to ADH stimulation may be due to renal resistance or receptor damage. On the other hand, neurogenic DI is from the word neuro meaning brain. In central or neurogenic DI, the problem lies in the gland secreting the hormone, which is the hypothalamus. There is decreased or absence of ADH secretion, therefore little or no stimulation occurs in the kidneys. As a result, large amount of water is excreted in the urine. Differentiation between nephrogenic and central DI may be done with the Continue reading >>

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  1. katrat01


    My 14 year old son was diagnosed with type 1 16 months ago. He takes injections 3 times a day. Last week he had a full blown seizure early in the morning. Immediately afterward his number was at 83. The paramedics gave him the glucose gel and his number dropped to 80. The doctors seem to think that it was brought on by low blood sugar while he slept. His desired numbers are from 100 to 120 so 83 was not out of range foir him. He gets a bit shaky around 65. Has anybody else gone through this? I know that the liver MIGHT kick in if the level goes drastically low, but would it kick in enough to bring it up that much? Please help!?!?

  2. serenity_of_the_heart

    from about the age of 6 to 14 i had a seizure disorder-i was diagnosed with diabets just before my 5th birthday-for awhile they thought it was caused by my diabetes but like your son my numbers were great when the seizures occured. The seizures ur the grand maul type. My advice is to get him into a doctor that specializes in seizure disorders and have him tested…what ended up happening in my case was that i had the seizures once a month always in the middle of the night and always my sugars were well within normal range. I ended up being put on a seizure med to prevent them and around the age of 14 i grew out of the seizures…just a suggestion to get him checked out by a doc that specializes in this sort of thing

  3. katrat01

    Thanks Serenity. Have an appt with Neuro in a month. Something about those teen years. Are any studies being done on that one?

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Please watch: "BOMB For Diabetes, Cholesterol, Infections And More | Diabetes BOMB" https://www.youtube.com/watch?v=PM00S... --~-- Watch DIABETES INSIPIDUS- Learn about the illness DIABETES INSIPIDUS- Natural Cures for DIABETES INSIPIDUS --------- Diabetes insipidus Vasopressin Specialty Endocrinology Symptoms Large amounts of dilute urine, increased thirst[1] Complications Dehydration, seizures[1] Usual onset Any age[2][3] Types Central, nephrogenic, dipsogenic, gestational[1] Causes Depends on the type[1] Diagnostic method Urine tests, blood tests, fluid deprivation test[1] Differential diagnosis Diabetes mellitus[1] Diabetes insipidus (DI) is a condition characterized by large amounts of dilute urine and increased thirst. The amount of urine produced can be nearly 20 liters per day.[ Reduction of fluid has little effect on the concentration of the urine.[1] Complications may include dehydration or seizures.[1] There are four types of DI, each with a different set of causes.] Central DI (CDI) is due to a lack of the hormone vasopressin(antidiuretic hormone).] This can be due to damage to the hypothalamus or pituitary gland or genetics Nephrogenic diabetes insipidus (NDI) occurs

Diabetes Insipidus - Endocrine - Medbullets Step 1

This patient is suffering from diabetes insipidus (DI). In a standard desmopressin test, an increase in urine osmolality of greater than 10% is highly suggestive of a diagnosis of central DI. Central DI is characterized by the failure of the hypothalamic-pituitary axis to produce and secrete sufficient levels of the hormone vasopressin (ADH). A desmopressin test is a highly useful diagnostic tool to differentiate between central (described above) and nephrogenic (resistance to ADH action in the kidneys) DI. The test involves injection of exogenous vasopressin. In central DI, injection of exogenous vasopressin will act to rectify the inappropriately low levels of endogenous ADH, leading to an increase in urine osmolality towards the normal range. In contrast, injection of ADH in the setting of nephrogenic ADH will not have any notable effect, as increasing ADH levels will not overcome the disease mechanism of renal resistance to ADH action. Adam describes the diagnostic protocol of DI in which the desmopressin test can help distinguish neurogenic from nephrogenic cases of DI. The treatment of neurogenic DI may involve nasal administration of desmopressin while nephrogenic DI requir Continue reading >>

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  1. Ken S

    Black Seed!

    Black seed is an amazing natural medicine, I've taken it in powder form but I wanted to try the oil, so it came today and I tried a dose (1500 mg of the oil). This is particularly noteworthy in it's lowering of fasting blood sugar, that's my big problem, it increases insulin secretion if it is low, improves insulin sensitivity, and even has been shown to restore lost beta cell function. So I tested when I got home, 6.5! Nothing less than a touch of Jesus' robe gets my fasting this low by the way. It's only one reading but has me excited! This is good stuff for blood sugar, as good as anything out there, prescription or otherwise, the powder was a little disappointing but this particular oil, from Amazing Herbs, which is supposed to have 5X the active ingredient of other brands, sure has amazed me so far!
    Effect of Nigella sativa seeds on the glycemic control of patients with type 2 diabetes mellitus.
    Bamosa AO1, Kaatabi H, Lebdaa FM, Elq AM, Al-Sultanb A.
    Author information
    Diabetes mellitus is a common chronic disease affecting millions of people world wide. Standard treatment is failing to achieve required correction of blood glucose in many patients. Therefore, there is a need for investigating potential hypoglycemic drugs or herbs to improve glycemic control in diabetic patients. Nigella sativa seeds were used as an adjuvant therapy in patients with diabetes mellitus type 2 added to their anti-diabetic medications. A total of 94 patient were recruited and divided randomly into three dose groups. Capsules containing Nigella sativa were administered orally in a dose of 1, 2 and 3 gm/day for three months. The effect of Nigella sativa on the glycemic control was assessed through measurement of fasting blood glucose (FBG), blood glucose level 2 hours postprandially (2 hPG), and glycosylated hemoglobin (HbA1c). Serum C-peptide and changes in body weight were also measured. Insulin resistance and beta-cell function were calculated usin the homeostatic model assessment (HOMA2). Nigella sativa at a dose of 2 gm/day caused significant reductions in FBG, 2hPG, and HbA1 without significant change in body weight. Fasting blood glucose was reduced by an average of 45, 62 and 56 mg/dl at 4, 8 and 12 weeks respectively. HbAlC was reduced by 1.52% at the end of the 12 weeks of treatment (P<0.0001). Insulin resistance calculated by HOMA2 was reduced significantly (P<0.01), while B-cell function was increased (P<0.02) at 12 weeks of treatment. The use of Nigella sativa in a dose of 1 gm/day also showed trends in improvement in all the measured parameters but it was not statistically significant from the baseline. However, no further increment in the beneficial response was observed with the 3 gm/day dose. The three doses of Nigella sativa used in the study did not adversely affect either renal functions or hepatic functions of the diabetic patients throughout the study period.
    the results of this study indicate that a dose of 2 gm/ day of Nigella sativa might be a beneficial adjuvant to oral hypoglycemic agents in type 2 diabetic patients.

  2. Ken S

    I guess they sent this to Siberia, too bad, I do want to say that discussions of any and all medications are normally permitted in the type 2 forum, prescription and non prescription ones both, as well as any and all other topics related to our disease, and this is definitely deserving of exposure, oh well.
    I don't even go to this corner of the forum actually, just here following my post.
    Ironically, black seed is as traditional of a treatment as you get, this was even mentioned in the Old Testament as a medicine, that's how far back it goes. It was also recommended by the prophet Mohammed, who said it is a remedy for everything but death. It was also used by modern folks like King Tut and even Hippocrates himself, known as the father of the blasphemy we call modern medicine nowadays. Non traditional indeed
    I'm not sure how threads on cinnamon and such stay and this one goes, just looking for a little more consistency folks.

  3. docmaas

    Well, it looks a lot safer than berberine which I have stopped after finding that suggested doses for humans are in the same order of magnitude range of mg/kg that resulted in cancer in both rats and mice. It's not easy to find as most of the research was done on goldenseal of which berberine is a constituent.
    blackseed toxicity: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846039/
    I agree that it should not have been moved. Looks like the admins are of the "place for everything and everything in its place" school. I'm at the opposite extreme but it really does seem that this kind of stuff should be in the more widely read forum.

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Diabetes Insipidus

Central diabetes insipidus is caused by reduced secretion of antidiuretic hormone (ADH). When target cells in the kidney lack the biochemical machinery necessary to respond to the secretion of normal or increased circulating levels of ADH, nephrogenic diabetes insipidus results. It occurs infrequently in dogs, cats, and laboratory rats, and rarely in other animals. Etiology: The hypophyseal form develops as a result of compression and destruction of the pars nervosa, infundibular stalk, or supraoptic nucleus in the hypothalamus. The lesions responsible for the disruption of ADH synthesis or secretion in hypophyseal diabetes insipidus include large pituitary neoplasms (endocrinologically active or inactive), a dorsally expanding cyst or inflammatory granuloma, and traumatic injury to the skull with hemorrhage and glial proliferation in the neurohypophyseal system. Clinical Findings: Affected animals excrete large volumes of hypotonic urine and drink equally large amounts of water. Urine osmolality is decreased below normal plasma osmolality (~300 mOsm/kg) in both hypophyseal and nephrogenic forms, even if the animal is deprived of water. The increase of urine osmolality above that o Continue reading >>

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  1. Claire Bear

    Can a Bedtime Snack Help Morning Highs?

    This is really interesting.
    I'm diet controlled T2. I can go to bed at 5.5 (99 i think) but I'll always wake up higher 7.8 (140ish) and absolutely starving. Would I be better to have a small snack before bed? Could that actually even my numbers out a little?

  2. Richard157

    Claire, if you do not eat a bedtime snack then your liver will start producing carbs in the middle of your night ang give you a morning high. This is called the Dawn Phenomenon. Many diabetics are frustrated by this at one time or another. The liver can produce more glucose than you really need. To keep this from happening just eat a bedtime snack consisting of something that will last well into the night. Peanut butter and a few crackers works well for many people. An Extend Bar or Solo Bar works well. These bars digest slowly and last throughout the night. They will produce glucose in small amounts at the time the liver might otherwise be producing much larger amounts. Your morning highs should improve greatly. If these bars cannot be found in the UK then you can use suitable substitutes that contain protein that digests slowly. Cheese or peanut butter is appropriate.
    Here is a site dealing with this problem:
    Good luck!

  3. Claire Bear

    Hi Richard,
    I just tried the link and it comes up ' Page cannot be displayed' . Sorry but I seem to be having one of those be totally dumb, stupid , airhead days. Any suggestions (other than a frontal lobotomy)?? (I mean't for the link)

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