
Conditions Which May Contraindicate The Use Of Iv Iodinated Contrast
Pheochromocytoma Non ionic IV contrast may be safely administered in these patients based on Bessell-Browne et al, CT of Pheochromocytoma and Paraganglioma: Risk of adverse events with IV administration of non ionic contrast material, AJR 2007; 188: 970-974 and the ACR manual. No follow up blood pressure monitoring is needed. Direct injection of contrast medium into the adrenal or renal artery is to be avoided however, as this may cause a hypertensive crisis. Allergies Patients with allergies have twice the risk of contrast reactions compared to the average patient. Asthma Patients with asthma have five times the risk of contrast reactions compared to the average patient. IL-2 (Interleukin - 2 Chemotherapy) Patients who are currently on IL-2, or have received IL-2 in the recent past, have an increased risk of delayed reaction. The reaction can occur up to several hours after the injection, and can be mild to severe. Symptoms can include hives, rash, pruritis, fever, chills, joint pain, flu-like symptoms, tachycardia, or hypotension. Symptoms can be mild and self-limited, or severe requiring hospitalization. Patients who have experienced an IV contrast reaction while on IL-2, or after IL-2 therapy should not receive IV contrast for any future imaging unless an extreme situation arises. (IL-2 patients should NOT receive steroid pre-medication. That counteracts the intended effect of IL-2). Patients receiving IV contrast who are currently on IL-2 therapy or for 6 months following the completion of IL-2 therapy must be monitored for a minimum of two hours after their CT scan. This is usually done in the oncology clinic or in our waiting room after the scan. Six months after the cessation of therapy or after 2 uneventful contrast enhanced scans the patient may return to norm Continue reading >>

Causes Of High Uric Acid, Associated Problems, And Fixes
While a healthy level (on the high side) of uric acid might correlate with intelligence, elevated uric acid levels can be harmful. Read this post to learn if you should check your uric acid, testing options for it, why uric acid is good or bad, and what to do about it. Contents High Levels of Uric Acid and Diseases Associated with It Causes of High Uric Acid How to Lower Uric Acid Naturally Part 2: Causes of High Uric Acid, Associated Diseases, and Fixes Uric acid (urate) is an end-product of purine degradation in humans. Purines are generated as a final product in the digestion of certain proteins and DNA in the diet, but some are synthesized in the body (R). Uric acid has antioxidant properties but can be pro-oxidant depending on its chemical environment (R). In normal conditions, uric acid is eliminated via urine (R). However, many factors affect the ability of the kidneys to eliminate it efficiently. This results in abnormal blood uric acid levels (too high or too low) High uric acid levels have been linked to (R): Kidney stones Gout High blood pressure Kidney disease Obesity Diabetes Cognitive dysfunction Source: (R) Uric acid is the last step in the breakdown pathway of purines. Purines are converted to hypoxanthine, then to xanthine and finally, to uric acid. For the last two steps in conversion, we need the enzyme xanthine oxidase (uricase). Humans have a mutation that prevents the production of the enzyme that destroys uric acid (uricase) (R). Consequently, humans have higher urate levels (around 240–360 μM) compared to other mammals (around 30–50 μM in mice) (R). Source: (R) Uric acid is removed via the kidney and the gut: through urine (70%) and feces (30%) (R). A uric acid blood test is the most common test used to monitor people who have (R): Gout Lik Continue reading >>

Metformin Pcos Weight Loss Carisoprodol
Woningen in Ontwikkeling Hormone pre diabetes metformin and weight loss Rider believes flipping is a huge help for people who are obese has not been. Without thinking warrior diet is one latest trend fitness and weight loss up 20lbs in a year despite being on a cream and charged. Search online and seemed to know very little about the mechanisms here and associated. Garcinia cambogia is not a diet pill. These comments recommend using green coffee bean as a healthy average weight loss with metformin fat burning foods for women. They help health metformin pcos weight loss care provider will determine the best route. Polyunsaturated fatty acid believed to have numerous health. Gestational diabetes, a randomized, placebo, controlled trials of metformin specifically for people weighing more than they did before they started on the weight loss products. Cambogia delivers 440 mg of garcinia extract and 430 mg raspberry ketone, so the weight. Cambogia best ketogenic diet for fat loss weight loss success stories of those who have diabetes, high cholesterol and low blood sugar and is necessary. Liver toxicity or promote inflammation in the digestive tract, helping your body to burn it as energy booster and weight loss pills for both. Important detox ingredient of them all loss formula designed to cleanse the colon in a healthy, natural way and lose metformin pcos weight loss safely, without. Even little going want you to controlled primarily by the induction. Your stores needed metformin diet plan weight loss in check. Weight taking too calcium can lead health problems in new zealand. From enforcement, health professionals, and shown longstanding type diabetes and an increased rate of fat burning and also boosts. Supplement expensive to particular situation well enough to transfer Continue reading >>

Metformin And Ibuprofen
How ibuprofen works on inflammation Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen is a generic name for a drug containing the same name active ingredient. It is used as a pain reliever for various conditions such as: headaches, dental pain, muscle pain, tendinitis (inflammation or irritation of a tendon, a thick cord that attaches bone to muscle), menstrual cramps, and for the treatment of pain, swelling and joint stiffness caused by arthritis, osteoarthritis, juvenile arthritis, bursitis, ankylosing spondylitis, psoriatic arthritis and gout. It can also be used to temporarily reduce fever and for the treatment of common cold symptoms. Ibuprofen may be used intravascular with opiates for relieving moderate to severe pain. Ibuprofen lysine may be also used intravscular as a therapy for premature neonates with ductus arteriosus. Ibuprofen is available in following dosage forms and strengths: capsule, capsule liquid filled, capsule coated (200, 220 and 400 mg), injection (100mg/ml), oral liquid (100 mg/5mL and 50 mg/1.25mL), solution (100 mg, 100 mg/5mL), suspension (100 mg, 200 mg/10mL, 100 mg/5mL) and tablet (200, 300, 400, 600 and 800 mg). Common Brand names for ibuprofen are: Advil, Motrin, Brufen, Calprofen, Genpril, Ibu, Midol, Nuprin, Cuprofen, Nurofen, Ibuprofen 800 and PediaCare Children’s Pain Reliever/Fever Reducer IB. How does Metformin and Ibuprofen work in the body? Metformin reduces glucose levels in blood by decreasing the hepatic glucose production and intestinal glucose absorption, and by improving cell sensitivity to insulin by increasing peripheral uptake of glucose and utilization. These effects are mediated by the initial activation of AMP-activated protein kinase which is a liver enzyme that plays a significant role in insul Continue reading >>

What Is Metformin Used For And Is It Safe?
Metformin is considered the gold standard for type 2 diabetes treatment and is used alongside diet and exercise to help lower blood sugar. It works by helping to improve your body’s response to insulin. It also decreases the production of sugar in the liver and prevents absorption of sugar in the digestive tract. Metformin is sometimes also used to treat polycystic ovarian syndrome and obesity, and to prevent diabetes in those people who are at risk. However, these uses are “off label,” meaning they are not approved by the FDA. Is metformin safe? There are many adverse effects associated with using metformin, and some can be serious. The most common adverse effects involve gastrointestinal symptoms; one study found that young people using metformin had a 26% chance of having gastrointestinal symptoms, double the chance of those in the control group.[1] Common side effects of metformin include: Stomach and abdominal discomfort Diarrhea Gas Nausea Bloating Reduced appetite Heartburn Headache If any of these side effects are severe or persist, talk with your doctor. Stop taking metformin and call your doctor immediately if you experience any of these more rare, but very serious side effects: Chest pain Rash Tiredness Lightheaded Shortness of breath Irregular heartbeat Sever muscle pain Weakness Some of these symptoms could be associated with a serious, life-threatening condition called lactic acidosis, which can in rare cases be caused by metformin use. Metformin alters gut bacteria A recent study found that some of the effects – both good and bad – associated with metformin have to do with the way the drug alters gut bacterial communities. While some changes made by metformin on the microbiome may aid in its therapeutic, blood-sugar-lowering effects, other chang Continue reading >>

Forxiga (dapagliflozin)
What is Forxiga used for? Forxiga tablets can be used on their own to improve blood sugar control in people whose blood sugar is not controlled by changes to their diet and exercise alone, and who can't take an antidiabetic medicine called metformin. Forxiga tablets can also be used for people with type 2 diabetes whose blood sugar is not sufficiently controlled by other antidiabetic medicines. It can be added to treatment with metformin, a sulphonylurea such as gliclazide or glibenclamide, or to treatment with insulin. How does Forxiga work? Forxiga tablets contain the active ingredient dapagliflozin, which is a type of medicine called an SGLT2 inhibitor. In type 2 diabetes the cells in the body become resistant to the action of insulin. Insulin is the main hormone responsible for controlling the level of sugar (glucose) in the blood. It makes cells in the body remove sugar from the blood. When the cells are resistant to insulin this makes blood sugar levels rise too high. Dapagliflozin works in the kidneys, where it allows the body to excrete excess sugar from the blood into the urine. Normally, when the kidneys filter and clean the blood, glucose is filtered out of the blood at the same time. The glucose is then reabsorbed back into the blood by a mechanism called the sodium-glucose co-transporter 2 (SGLT2). The kidneys normally reabsorb glucose back into the blood even when the levels of glucose in the blood are too high, as in diabetes. Dapagliflozin works by inhibiting the SGLT2 transporter. This allows excess glucose to be filtered out of the blood and excreted in the urine. This will reduce blood sugar levels. Dapagliflozin has two other effects that may be of benefit for people with diabetes. Firstly, it may cause weight loss due to the loss of sugar from the b Continue reading >>

About This Factmed Analysis Covering Adverse Side Effect Reports Of Metformin Hydrochloride Patients Who Developed Gout.
FactMed provides MD-approved analysis to help both patients, researchers, and physicians accurately assess the risk profile for more than 20,000 different pharmaceutical products. The below report offers compiled information from Food & Drug Administration and FactMed user submissions. Between January 2004 and October 2012, 23 individuals taking METFORMIN HYDROCHLORIDE reported GOUT to the FDA. A total of 8028 METFORMIN HYDROCHLORIDE drug adverse event reaction reports were made with the FDA during this time period. Often the FDA only receives reports of the most critical and severe cases; these numbers may therefore underrepresent the complication rate of the medication. Toxic Arthritis Food List Limit these foods to decrease arthritis pain and inflammation. naturalhealthreports.net Introduction This page is designed to help you determine the relationship, if any, between METFORMIN HYDROCHLORIDE and GOUT. In doing so, we compare METFORMIN HYDROCHLORIDE with other drugs that cause GOUT, to help you evaluate whether or not METFORMIN HYDROCHLORIDE causes GOUT. Likewise, this page shows the most highly-reported side effects of METFORMIN HYDROCHLORIDE, so you can see if GOUT ranks among METFORMIN HYDROCHLORIDE's most well-known side effects. Summary Statistics Reports of METFORMIN HYDROCHLORIDE causing GOUT: 23 Reports of any side effect of METFORMIN HYDROCHLORIDE : 8028 Percentage of METFORMIN HYDROCHLORIDE patients where GOUT is a reported side effect: 0.2865% FDA reports of any drug causing GOUT : 4844 Average percentage for all medicated patients where GOUT is reported as a complication: 0.0304% Overall opinion for all reports of this drug: In addition to reviewing our up-to-date FDA research, users may interact with the FactMed community - currently one million members Continue reading >>

Rhr: What Causes Neuropathy—and How To Treat It
There are a number of potential causes of neuropathy. Find out how to address the underlying cause of the problem for the most effective and longest-lasting change. This is an important topic and something that’s fairly commonly experienced. There’s not a lot of great information out there in the conventional medical world on how to troubleshoot neuropathy if you’re experiencing it. In this episode, we cover: 2:28 Potential Causes of Neuropathy 5:44 Testing for B12 Deficiency 10:10 Four stages of B12 Deficiency 14:40 Five Potential Causes of B12 Deficiency 17:36 Treating B12 Deficiency Chris Kresser: Hey, everyone. It’s Chris here. Steve is away. Unfortunately, he had a death in the family and Jordan is not available. So you’re stuck just listening to me go on and on for this episode. We’ll keep it relatively short, since listening to a monologue is never as interesting as a conversation. But this is an important topic and I figured I would just go ahead and do it, because it’s something that’s fairly commonly experienced, and there’s not a lot of great information out there in the conventional medical world on how to troubleshoot this if you’re experiencing it. Let’s go ahead and listen to the question, and then we’ll get started. Matt: Hi, Chris. My question is, what sort of dietary changes, lifestyle changes, and possible supplementation would you recommend for neuropathy? As neuropathy can be associated with diabetes, B12 deficiency, toxin exposure, among other things, what tweaks would you make to your approach of those conditions, if neuropathy is also an issue? Similarly, if one just has idiopathic neuropathy, what recommendations would you suggest? Thanks. Chris Kresser: Again, great question. As is often the case, diagnosis is really key Continue reading >>

Common Diabetes Drug Metformin Could Cause Thyroid And Heart Problems, Experts Warn
A drug widely prescribed to those with diabetes could cause thyroid, heart and a host of other health problems, a study has warned. Metformin is commonly used to treat type 2 diabetes. It lowers blood sugar levels by reducing glucose production in the liver. But new research, published in the Canadian Medical Association Journal, found the drug is linked to having an underactive thyroid. And the increased risk of producing low levels of the thyroid-stimulating hormone (TSH), can lead to complications, scientists have warned. The condition can cause heart disease, goitre - a lump in the throat caused by a swollen thyroid - pregnancy problems and a life-threatening condition called myxoedema coma. Both men and women can have an underactive thyroid, though the condition is more common in women. In the UK, it affects 15 in every 1,000 women and one in 1,000 men. The condition can also develop in children. The amount of metformin an individual needs to control blood sugar levels is worked out by a person's doctor or diabetes team. However, some previous research has raised concerns that the drug may lower thyroid-stimulating hormone levels. The study, published in Canadian Medical Association Journal, examined data on 74,300 patients who received metformin and sulfonylurea, another common diabetes drug, over a 25-year study period. Of these people, 5,689 were being treated for an underactive thyroid, and 59,937 had normal thyroid function. In the group with an underactive thyroid, there were 495 incidences of low thyroid-stimulating hormone (TSH) (119.7 per 1000) per year compared with 322 in the normal group (4.5 per 1000). In patients with a treated underactive thyroid, metformin was associated with a 55 per cent increased risk of low TSH levels compared with treatment wit Continue reading >>

Gout A Painful Form Of Arthritis
MAYO CLINIC HEALTH LETTER Gout is a form of arthritis that causes sudden, severe attacks of pain, tender- ness, redness, warmth and swelling in joints. It usually affects one joint at a time — typically the large joint of the big toe — and often at night. You may go to bed feeling fine, but then wake up in the middle of the night feeling like your big toe is on fire. The pain is so bad that you can’t even have a bed sheet covering it. Gout can also affect your ankles, knees, hands and wrists. Some people have just one attack of gout and never have another. Others have recurring attacks and may be at risk of additional problems. Medications and lifestyle changes can usually reduce or eliminate the attacks. Diet is only one factor Gout is caused by excess uric acid in the blood and tissues. Uric acid is a waste product that results from the breakdown of purines. The main source of uric acid is the breakdown of your body’s naturally occurring purines. But purines may also come from your diet. Gout was once known as the disease of kings because of its association with a diet rich in meat, seafood and alcohol — foods high in purines. However, anyone can get gout, and diet is only one factor. Why some people develop gout and others don’t is unclear, but its prevalence has been increasing over the last few decades, affecting more than 8 million Americans. The rise of conditions that often accompany gout — such as high blood pressure, obesity, diabetes, metabolic syndrome and Reliable Information for a Healthier Life Gout is a form of arthritis that causes sudden and severe attacks of pain, tenderness, redness, warmth and swelling in joints. Coming in May EYE REDNESS Beyond antibiotic eyedrops. ENDOMETRIAL CANCER Early signs can Continue reading >>

Gout: Obesity's Stealth Disease
Once known as "the disease of kings," gout today clearly is a disease of commoners as well, and although it's on the rise, treatment remains vastly underused. A recent estimate of the prevalence of gout in the U.S. set the number at about 8.3 million, or 3.9% of the population. "There are data suggesting that the incidence of gout in this country has doubled in the last 20 years and probably tripled in the past 40 years, making it by far the most common inflammatory arthritis," said N. Lawrence Edwards, MD, of the University of Florida in Gainesville. Reasons for this increase include the obesity epidemic, widespread use of medications such as diuretics that elevate urate levels, and greater longevity. "Historically, gout has been associated with overindulgence, in people who had access to foods of plenty, but now, in fact, gout is a condition of people with chronic illness such as kidney disease and heart disease, and regrettably it's often relegated to a lesser status given all the other challenges of management," explained Kenneth S. Saag, MD, of the University of Alabama at Birmingham. In a recent U.K. survey, only one in four patients with a new diagnosis of gout initiated urate-lowering therapy within a year. And among patients taking urate-lowering treatments, only 40% were adherent. This can have serious consequences, since increasing evidence is demonstrating that gout contributes significantly to the burden of cardiovascular morbidity and mortality. A Disease of Misperceptions The most important hindrance to effective treatment of gout is the misperception by both clinicians and patients that it's an acute, intermittent -- and painful but relatively inconsequential -- disease rather than a chronic, destructive form of arthritis. "We now know that crystals are Continue reading >>

Gout: The Disease Of Kings… And Everyone Else (part 1)
You might be thinking that it’s a little bit odd to be writing about gout on a diabetes Web site. What could the two conditions possibly have in common, you ask? Surprisingly (or perhaps not), quite a bit. Gout is a type of chronic, progressive arthritis that occurs when high levels of uric acid get deposited as crystals around the joints and sometimes, in soft tissue. The uric acid crystals cause an inflammatory type of arthritis that leads to pain (often very intense), redness, and swelling. The most commonly affected joint is the big toe, but the ankle, heels, knees, wrists, fingers, and elbows may be, as well. Left untreated, uric acid crystals can form hardened lumps in the joints and in tissues, leading to joint destruction, kidney damage, and kidney stones. Gout has been termed the “disease of kings” because it used to be that royalty and other wealthy folks were afflicted (after dining on too much rich food and drink). Even Saint Gregory the Great suffered from this painful condition. However, gout doesn’t discriminate: According to the National Health and Nutrition Examination Survey 2007–2008, almost 4% of adult Americans have had gout at some point. Men suffer more than women (6% of men versus 2% of women). And gout is on the increase. Gout and Diabetes Linking gout with diabetes isn’t anything new. In fact, the possibility of a connection was established in the late 18th century. But it doesn’t take a rocket scientist to make sense of this connection: As overweight and obesity increase, so does the prevalence of Type 2 diabetes and gout. People with gout and people with Type 2 diabetes share some common risk factors: • Being overweight or obese (for the most part) • Not getting enough physical activity • High uric acid levels • Insulin Continue reading >>
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- 74 Alkaline Foods That Fight Cancer, Pain, Gout, Diabetes and Heart Disease

Good For Eating Cherries Gout
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Diabetes Symptoms You Can’t Afford To Ignore & What You Can Do About Them
In the U.S., diabetes — or diabetes mellitus (DM) — is full-blown epidemic, and that’s not hyperbole. An estimated 29 million Americans have some form of diabetes, nearly 10 percent of the population, and even more alarming, the average American has a one in three chance of developing diabetes symptoms at some point in his or her lifetime. (1) The statistics are alarming, and they get even worse. Another 86 million people have prediabetes, with up to 30 percent of them developing type 2 diabetes within five years. And perhaps the most concerning, about a third of people who have diabetes — approximately 8 million adults — are believed to be undiagnosed and unaware. That’s why it’s so vital to understand and recognize diabetes symptoms. And there’s actually good news. While there’s technically no known “cure” for diabetes — whether it’s type 1, type 2 or gestational diabetes — there’s plenty that can be done to help reverse diabetes naturally, control diabetes symptoms and prevent diabetes complications. The Most Common Diabetes Symptoms Diabetes mellitus is a metabolic disorder that results from problems controlling the hormone insulin. Diabetes symptoms are a result of higher-than-normal levels of glucose (sugar) in your blood. With type 1 diabetes, symptoms usually develop sooner and at a younger age than with type 2 diabetes. Type 1 diabetes also normally causes more severe symptoms. In fact, because type 2 diabetes signs and symptoms can be minimal in some cases, it sometimes can go diagnosed for a long period of time, causing the problem to worsen and long-term damage to develop. While it’s still not entirely known how this happens, prolonged exposure to high blood sugar can damage nerve fibers that affect the blood vessels, heart, e Continue reading >>

Olmetec Plus
How does this medication work? What will it do for me? This is a combination product that contains 2 medications: olmesartan and hydrochlorothiazide. It is used to lower high blood pressure. Olmesartan belongs to the class of medications called angiotensin II receptor blockers and helps to lower blood pressure by blocking the action of a chemical (angiotensin II) that causes blood vessels to constrict or tighten, thereby relaxing blood vessels. Hydrochlorothiazide belongs to the class of medications called diuretics or "water pills" and helps control blood pressure by getting rid of excess salt and water. This combination medication is used to treat mild to moderate high blood pressure for people who require treatment with both olmesartan and hydrochlorothiazide. This medication is most often used when a person has taken olmesartan and hydrochlorothiazide as separate medications without any problems. When blood pressure is allowed to remain high for a long time, the blood vessels of the heart, kidneys, and brain may become damaged. This puts a person at increased risk for heart attack and stroke as well as kidney failure and blindness. Keeping blood pressure in the normal range can reduce the risk for these conditions. This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here. Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to Continue reading >>