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Blood Transfusion For Diabetes

Diabetes May Spread Through Toxic Meat Or Blood Transfusions, Leading Scientist Warns

Diabetes May Spread Through Toxic Meat Or Blood Transfusions, Leading Scientist Warns

The protein seeds are similar to those which carry mad cow disease from cattle to humans. Experiments in genetically modified mice show that injecting them with the toxic clusters led to them developing all the symptoms of type 2 diabetes within weeks. Similar chemical signatures were also observed when the proteins were added to healthy human pancreatic tissue in a dish, according to a paper published in the Journal of Experimental Medicine. Experts said it was not at all clear that the same mechanisms would work in humans and that there is as yet no good evidence that the disease is contagious. The senior author of the study, Professor Claudio Soto, said his team was investigating the possibility that type 2 diabetes could be acquired by ingesting “rogue” proteins in animal products. He said: “I don’t want to scare anyone, but I can see this happening in diabetes more easily than it happens in brain diseases, because in brain diseases the spread is limited by the blood-brain barrier. “If one disease has the potential to be transmitted in this manner, it is diabetes.” However David Allsop, professor of neuroscience at Lancaster University, said the research was far from proven. Wed, June 28, 2017 Incredible medical breakthroughs leading to promising new treatments are just around the corner. Take a look at some of the most recent discoveries. Mr Allsop said: “This conclusion needs to be treated with a great deal of caution. This type of mechanism could explain the spread of pathology to areas of adjacent tissue, but it is a big jump to suggest that diabetes is an infectious disease.” Type two Diabetes is heavily linked to obesity and insulin resistance. Since the 1970s scientists have noticed that more than 90 per cent of type 2 diabetics have deposits Continue reading >>

Anaemia In Patients With Diabetes: Unrecognised, Undetected And Untreated?

Anaemia In Patients With Diabetes: Unrecognised, Undetected And Untreated?

This survey clearly demonstrates that patient awareness of the ramifications of anaemia is surprisingly low and also suggests that physicians are neither testing for anaemia in terms of a simple red blood cell count nor treating anaemia in patients with diabetes. The shortfall of information provided by healthcare professionals also reflects the lack of routine testing - only 1% of respondents were aware of being tested for anaemia during routine visits to the doctor or nurse. Over half of all patients with diabetes were not aware of being checked for anaemia since their diagnosis. There seems to be an information gap with regard to anaemia - patients with diabetes have not been making the link between any tiredness they experience and anaemia. Since little information is given to patients with diabetes directly by healthcare professionals, any knowledge on the subject would appear to have been accumulated 'along the way'. This is probably why patients with diabetes are likely to focus on diet as both the cause of, and the cure, for anaemia. However, many patients with diabetes do associate their anaemia with diabetes as a 'background' cause, without making any specific causal connection. Those patients with diabetes diagnosed with kidney problems were more likely to identify diabetes as a cause of their anaemia, although without making the connection between diabetes, renal problems and anaemia. Patients with diabetes are at increased risk from adverse cardiovascular outcomes associated with chronic renal insufficiency.[ 10 ] The cardiovascular disease burden is even greater at initiation of dialysis and includes coronary artery disease, left ventricular dysfunction, left ventricular hypertrophy (LVH) and cardiac failure.[ 11 , 12 ] Cardiovascular disease causes 50% o Continue reading >>

What Is A Blood Transfusion? Risks, Procedure & Side Effects

What Is A Blood Transfusion? Risks, Procedure & Side Effects

A blood transfusion is the transfer of blood or blood products from one person (donor) into another person's bloodstream (recipient). This is usually done as a lifesaving maneuver to replace blood cells or blood products lost through severe bleeding, during surgery when blood loss occurs or to increase the blood count in an anemic patient. The following material is provided to all patients and/or their family members regarding blood transfusions and the use of blood products. Although in most situations the likelihood of a blood transfusion associated with surgery is uncommon, at times patients may require blood products. You are encouraged to discuss your particular need for transfusion as well as the risks of transfusion with your doctor. Your options may be limited by time and health factors, so it is important to begin carrying out your decision as soon as possible. For example, if friends or family members are donating blood for a patient (directed donors), their blood should be drawn several days prior to the anticipated need to allow adequate time for testing and labeling. The exact protocols are hospital and donor site specific. The safest blood product is your own, so if a transfusion is likely, this is your lowest risk choice. Unfortunately this option is usually only practical when preparing for elective surgery. In most other instances the patient cannot donate their own blood due to the acute nature of the need for blood. Although you have the right to refuse a blood transfusion, this decision may have life-threatening consequences. If you are a parent deciding for your child, you as the parent or guardian must understand that in a life-threatening situation your doctors will act in your child's best interest to insure your child's health and wellbeing in Continue reading >>

Can One Donate Blood With Diabetes, Cholesterol, Controlled Blood Pressure And After Cured Tuberculosis?

Can One Donate Blood With Diabetes, Cholesterol, Controlled Blood Pressure And After Cured Tuberculosis?

Medical Conditions and blood donation As per the Drugs and Cosmetics Act and guidelines from national blood transfusion council the medical conditions mentioned for deferral is vague and incomplete and hence the medical officer has got the discretion to take or defer donation based on recent developments in modern medicine. According to Dr Sunder Periyavan, Additional Professor, Officer in charge, Transfusion Medicine Center, NIMHANS, Bangalore - Diabetes with medication: A. Type I diabetes who is on Insulin (Injection) are to be deferred. This is because these patients can have extreme levels of blood glucose with or without insulin. Lower levels of blood glucose will have effect on blood donation because blood removal will further bring down the glucose level to bring about symptomatic hyplogycemia which is dangerous. And type I diabetes will have higher chance skin infection at the site of needle prick. B. Type II diabetes who is on oral diabetic drug can donate blood. This is because the blood glucose levels are not that extreme and even with 350/450 ml of blood with drawls will not cause symptomatic hypoglycemia. Since their blood levels are fairly maintained the chances of skin infection is less. Diabetes without medication: Since we do not know the blood glucose levels-high or low and at the camp site we do not test for glucose levels it is better to avoid bleeding the donor. High Cholesterol: high cholesterol is an abnormal condition for the donor. If blood 350/450 ml of blood is drawn from the donor and transfused it gets diluted in patients’ blood and the level will not be that high. And the patient can metabolize it brings down the level original level. It is as if the patient has taken a fatty meal. Hence blood donation is acceptable. And if the donor repe Continue reading >>

Diabetes And Blood Transfusion? - Diabetes - Medhelp

Diabetes And Blood Transfusion? - Diabetes - Medhelp

Forums > Diabetes >Diabetes and blood transfusion? This expert forum is not accepting new questions. Please post your question in one of our medical support communities . My friend's mom went hypoglycemic n eventually got comatose after the doctor miscalculated her medication.She is depending on a ventilator for the meantime due to very low RBC as well.She had blood transfusion to help her RBC go back to normal count for better oxygen circulation.Question: Can you tell me what's going on with her?I can't understand if she has mere diabetic case that is aggravated by certain antibiotic medication like bactrim or she has blood problem.. whatever it is I am confused... could anyone enlighten me about this? I think your Mom's situation may be more complicated and I would need to know more about her medical course to really give you an idea of what is going on. For your Mom to have become comatose after going low in her sugar, she would have had to have had a very serious event while low, like a series of seizures, a stroke or a heart attack, or stayed low for too long and thus suffered some brain damage. Many folks also do not become ventilator-dependent only from anemia; usually there is something else going on. There is no direct connection between diabetes and a very low blood count unless you have autoimmune diseases that cause both(quite uncommon). People with diabetes can tend to have lower counts than those without, but not terribly lower. Many things can affect how your Mom's body handles her diabetes medication, and possibly many of them are not quite normal right now, including her kidney functions and liver functions, as well as medication interactions. I am afraid I cannot offer you specific suggestions about this. I do suggest speaking perhaps with the hospita Continue reading >>

Can Diabetes Be Transferred Through Blood Transfusion?

Can Diabetes Be Transferred Through Blood Transfusion?

As we’re not entirely sure what causes type I diabetes, this question is far from easy to answer. There are some that maintain that this is primarily an autoimmune disease and there are those that believe that some pathogen, probably a virus is involved. There is always a risk of transmitting diseases with a blood transfusion and for this reason we don’t give transfusions unless it’s absolutely necessary. We also generally exclude individuals with diabetes, cancer, hepatitis, HIV and other chronic diseases and infections from being blood donors as we know that there is a risk that some of these conditions can or could potentially be spread with a blood transfusion. Type II diabetes on the other hand is a metabolic disorder that is primarily connected to lifestyle and genetic susceptibility and those can't be transferred through a blood transfusion. Continue reading >>

Excess Glucose Limits Blood Transfusion Success

Excess Glucose Limits Blood Transfusion Success

Excess glucose limits blood transfusion success Cell-to-cell communications in blood donations are disrupted if storage solutions contain too much glucose Reducing the level of glucose in solutions used to process blood donations could benefit patients receiving blood transfusions , new research shows. The storage of blood donations is a great challenge as the longer blood is stored, the more it deteriorates. Red blood cells (RBCs) are often collected in solutions containing glucose to preserve and extend their shelf-life, but these solutions may also be adversely affecting the blood as well as patients receiving it. In the same way that untreated high blood sugar in diabetics can lead to serious medical conditions, complications associated with blood transfusions might be due to the high levels of glucose currently used to store RBCs after donation often almost 10 times the bloodstream glucose level in a healthy person. This rationale was the motivation behind the research of Dana Spence and his team at Michigan State University in East Lansing, US, who used a microfluidic system to maintain a constant, low level of glucose in blood storage solutions, and then assessed the impact this had on the RBCs. By reducing the glucose levels, we saw that the red blood cells were able to release increased amounts of ATP [adenosine triphosphate] which, in turn, can stimulate nitric oxide in other cell types, says Spence. He goes on to explain that nitric oxide is essential for maintaining blood flow and low nitric oxide bioavailability is a recognised problem associated with transfusion. Christopher Silliman , an expert in blood banking and transfusions at the Bonfils Blood Center in Denver, Colorado, US, says the results are compelling and may lead to improved storage techniques Continue reading >>

5 Diabetes Myths

5 Diabetes Myths

I've had diabetes for over 16 years now and there were times I would hear things about diabetes that were just completely false. I'm sure this is the case for a lot of diabetics as well. Below are some of the myths that seem to come up quite often. Myth #1: Diabetics can't eat sweets The first thing that comes to people's minds when they first meet a diabetic is probably how it sucks to not be able to eat chocolate or ice cream. While sugar does seem to be the enemy, it's completely ok for diabetics to eat sweets as long as they're watching their blood glucose levels. For diabetics like me who take insulin, for example, we can make adjustments to the amount of insulin we take to account for the extra glucose. They key thing is being able to control our blood sugar levels and we can pretty much eat anything non-diabetics can eat without the risk of any complications. Myth #2: Diabetes is contagious Diabetes occurs when a person's pancreas is not producing enough insulin, not producing any insulin at all, or the body is just not responding properly to the insulin produced. You can't catch it from making contact with people with diabetes or even through blood transfusion. Myth #3: Only old people can get diabetes I actually thought this was the case as well when I was younger, until I developed the disease myself when I was 13. It's true that a lot of people who are diagnosed with Type 2 diabetes tend to be older, usually over 40, but you can develop diabetes (Type 1 or Type 2) at any age. There was a point that Type 1 diabetes (usually insulin dependent) was referred to as 'juvenile diabetes' as it was pretty rare and only seemed to occur in children and young adults. But it is now known that you can get either type at any age. Myth #4: Eating too much sugar causes diabet Continue reading >>

Could Diabetes Spread Like Mad Cow Disease?

Could Diabetes Spread Like Mad Cow Disease?

Prions are insidious proteins that spread like infectious agents and trigger fatal conditions such as mad cow disease. A protein implicated in diabetes, a new study suggests, shares some similarities with these villains. Researchers transmitted diabetes from one mouse to another just by injecting the animals with this protein. The results don’t indicate that diabetes is contagious like a cold, but blood transfusions, or even food, may spread the disease. The work is “very exciting” and “well-documented” for showing that the protein has some prionlike behavior, says prion biologist Witold Surewicz of Case Western Reserve University in Cleveland, Ohio, who wasn’t connected to the research. However, he cautions against jumping to the conclusion that diabetes spreads from person to person. The study raises that possibility, he says, but “it remains to be determined.” Prions are misfolded proteins that can cause normally folded versions of the same protein to misfold themselves. When this conversion occurs in the brain, the distorted proteins bunch up inside cells and kill them. Although prion diseases are rare in people, they share some similarities with more common illnesses. In Alzheimer’s disease, for instance, globs of a misshapen protein known as β amyloid build up in the brain. Parkinson’s disease and Huntington disease, two other brain maladies, also feature aggregates, or lumps of misfolded proteins. Get more great content like this delivered right to you! By signing up, you agree to share your email address with the publication. Information provided here is subject to Science's privacy policy. At first glance, type 2 diabetes, in which people lose the ability to control their blood glucose levels, doesn’t seem to have any connection to prions Continue reading >>

Type 2 - Can Blood Transfusion Correct Blood Sugars | Diabetes Forum The Global Diabetes Community

Type 2 - Can Blood Transfusion Correct Blood Sugars | Diabetes Forum The Global Diabetes Community

Diabetes Forum The Global Diabetes Community Find support, ask questions and share your experiences. Join the community Type 2 Can blood transfusion correct blood sugars I had a hip replacement in December 2016 and needed to have 2 blood transfusions.. By the third day I noticed that hypos were occurring at least twice a day. When I got home 9 days later I noticed that my sugar levels where between 5 and 6; night time readings where no higher than 7 before bed. I decided to find out if this was a fluke so i took 1.2 Victoza in the morning. I happily dug into cake and custard and had as couple of chocolate bars (delicious) in the afternoon. I did not take novorapid after. I did not test myself until 10pm prior to having my nighttime insulin Lanctus @40 units. To my surprise my blood sugar reading was 9.1 instead of 7, so it didn't really go too high. Prior to my operation my hba1c was 55, this week its come back at 43.. Can anyone explain what happened or have you experienced this. So far I have stopped novorapid as the hypos where happening everyday. I had a hip replacement in December 2016 and needed to have 2 blood transfusions.. By the third day I noticed that hypos were occurring at least twice a day. When I got home 9 days later I noticed that my sugar levels where between 5 and 6; night time readings where no higher than 7 before bed. I decided to find out if this was a fluke so i took 1.2 Victoza in the morning. I happily dug into cake and custard and had as couple of chocolate bars (delicious) in the afternoon. I did not take novorapid after. I did not test myself until 10pm prior to having my nighttime insulin Lanctus @40 units. To my surprise my blood sugar reading was 9.1 instead of 7, so it didn't really go too high. Prior to my operation my hba1c was 55, t Continue reading >>

Umbilical Cord Blood Infusion To Treat Type 1 Diabetes

Umbilical Cord Blood Infusion To Treat Type 1 Diabetes

You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Umbilical Cord Blood Infusion to Treat Type 1 Diabetes The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. ClinicalTrials.gov Identifier: NCT00305344 Information provided by (Responsible Party): Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More Information While this study is now completely enrolled, we do hope to develop a "next generation" cord blood based study sometime in early 2009. Please continue to contact us if you have a child with newly diagnosed Type 1 Diabetes (T1D) who alo has their OWN cord blood in storage. Procedure: Autologous Umbilical Cord Blood Transfusion Biological: Cord blood Transfusion of Autologous Umbilical Cord Blood to Reverse Hyperglycemia in Children With Type 1 Diabetes - A Pilot Study Procedure: Autologous Umbilical Cord Blood Transfusion Children With T1D Underwent a Single Autologous UCB Transfusion [TimeFrame:Baseline to Year 2] All participants were monitored for 2 years. Baseline and post-infusion mixed meal tolerance tests were performed to determine whether autologous cord blood infusion preserved endogenous insulin production. The change in median area under the curve for C-peptide (measure of insuln production) from baseline to to 2 years during a 2 hour mixed meal tolerance test was used as the primary outcome measure and was reported in ng/ml/120 minutes Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More Continue reading >>

Red Cell Transfusion Decreases Hemoglobin A1c In Patients With Diabetes

Red Cell Transfusion Decreases Hemoglobin A1c In Patients With Diabetes

Hemoglobin A1c (Hb A1c)1 is a mainstay of diabetes diagnosis and management that allows clinicians to estimate the recent mean blood glucose concentration of a patient. Glycation of hemoglobin is an irreversible, nonenzymatic process that depends on the glucose concentration in red blood cells (RBCs), and Hb A1c represents the integrated glucose concentration in RBCs over their life span. RBC transfusion can complicate the interpretation of Hb A1c values in diabetic patients because it introduces hemoglobin molecules exposed to glucose concentrations that may have been different from the glucose concentrations in the diabetic transfusion recipient. The potential effect of transfusion on Hb A1c has been recognized for some time, but opinions on the direction of the effect are contradictory. Data from the older literature (1–3) suggest that the high concentration of glucose in RBC storage medium promotes glycation and causes Hb A1c values to increase over time, which would predict that Hb A1c might increase in transfused patients. This concept has been stated in a recent review article (4) and on consumer Web sites, such as Lab Tests Online (however, a recent case in which a pathology resident was contacted to explain a patient's Hb A1c value decreasing from 7.4% to 5.4% in 3 days after the patient received 3 units of RBCs suggested that transfusion may lower Hb A1c values in diabetic patients. Indeed, the majority of blood donors are not diabetic, and donor RBCs would dilute the increased Hb A1c value (>6.5%) in a diabetic patient. To our knowledge, no study has used contemporary Hb A1c methods to examine the effect of RBC storage conditions on Hb A1c or the overall effect of RBC transfusion on Hb A1c in patients. To investigate these questions, we used an immunoassay Continue reading >>

Can I Donate Blood If I Have Diabetes?

Can I Donate Blood If I Have Diabetes?

Donating blood is a selfless way to help others. Blood donations help people who need transfusions for many types of medical conditions, and you may decide to donate blood for a variety of reasons. A pint of donated blood may help up to three people. Although you’re allowed donate blood if you have diabetes, there are a few requirements that you’ll need to meet. If you have diabetes and want to donate blood, it’s generally safe for you to do so. People with type 1 and type 2 diabetes are eligible to give blood donations. You should have your condition under control and be in otherwise good health before you donate blood. Having your diabetes under control means that you maintain healthy blood sugar levels. This requires you to be vigilant about your diabetes on a daily basis. You need to be aware of your blood sugar levels throughout each day and make sure you eat a proper diet and exercise sufficiently. Living a healthy lifestyle will contribute to keeping your blood sugar levels in a healthy range. Your doctor may also prescribe certain medications to help manage your diabetes. These medications shouldn’t impact your ability to donate blood. If you want to donate blood but are concerned about your diabetes, talk to your doctor before your donation. They can answer any questions you may have and help you determine whether this is the best option for you. Health screening Blood donation centers have a screening process that requires you to disclose any preexisting health conditions. It’s also a time where a certified Red Cross professional will evaluate you and measure your basic vital statistics, such as your temperature, pulse, and blood pressure. They will take a small blood sample (likely from a finger prick) to determine your hemoglobin levels as well. If Continue reading >>

Effects Of Packed Red Cell Transfusion On Blood Glucose Concentrations In Beta Thalassemia Major (btm) Ashort Presentations Of Personal Experience

Effects Of Packed Red Cell Transfusion On Blood Glucose Concentrations In Beta Thalassemia Major (btm) Ashort Presentations Of Personal Experience

The most accurate method with which to evaluate altered glucose metabolism in patients with TM is still controversial. Even if the annual oral glucose tolerance test (OGTT) by the age of 10 years is the recommended method, a diagnosis of 'normal' glucose tolerance during OGTT does not exclude abnormal postprandial glucose levels at home . There is now evidence that the OGTT method, evaluating fasting and 2-h post load glucose, may miss episodes of hyperglycaemia . Furthermore, the credibility of Hb A1c has been questioned because the hemoglobin composition of patients' erythrocytes are considerably modified, due to regular and frequent transfusions. The results may be falsely increased or decreased depending on the proximity to transfusion, shortened erythrocyte lifespan and the assay used . It has been demonstrated recently that the continuous glucose monitoring system (CGMS) is a useful and valid tool in defining glucose metabolism in children and adults affected by TM with early glucose derangements . Indeed, the CGMS allows monitoring of glycaemic profiles throughout a period of 72 h for a total of 288 glycaemic registrations per day. It identifies glycaemic excursions and constitutes a valid device to understand the 24-h glycaemic trend and profiles. Rimondiet al. investigated the value of using CGMS in six TM patients with abnormal glucose homeostasis after an oral glucose tolerance test (OGTT) . Two-hour OGTT glucose values and CGMS fluctuations were classified as normal if < 7.8 mmol/l, impaired if 7.8 to 11.1 mmol/l, diabetic if > 11.1 mmol/l. The TM patients spent from 1 to 23% of the time with a blood glucose level from 7.8 to 11.1 mmol/l. we evaluate three patients with Beta Thalassemai major using CGMS Patient 1 A 15 year old male with TM presented with noc Continue reading >>

Blood Transfusion | Diabetic Connect

Blood Transfusion | Diabetic Connect

I was wondering if a blood transfucion could cure a body of diabetes? Even with a pancreatic transplant, you are really only trading your diabetes medications for anti rejection drugs. Still chronic. Still a lifelong thing to deal with. I would rather keep my broken pancreas and wear my pump than subject my already broken self to a transplant and all that would entail. Being diabetic is difficult enough with my own pancreas why take a chance on someone else's ;-) I was joking with my dr and mentioned I could just get a new pancreas, and he said no because that would only last for a couple of years and then I would be worse off then before the transplant. He went on to explain why, too long to go through explaination here. Sure did burst my bubble:( There is no cure for diabetes and the only thing that would help is a pancreas transplant. That still isn't a guarantee that you won't develop diabetes. Other than a pancreatic transplant, there isn't a cure for diabetes. I sure wish it was as easy as a blood transfusion :) Nope it don't work like that ,if only it did I had one friend who was a type 1 diabetic for 35 yearsa brittle diabetic She had a pancreatic transplant, it worked successfully, and she had to go through the medication to stablize the new organbut her body still had the effects of years of diabetesbut to have a transplant like that you have to be in a position of dire straits Hey Scarlett I got an email that you responded to my response to you but I don't see it here or on my profile page. This keeps happening, I get the email and no one has responded. This is weirdlol Scarlett, someone here in MD got a transplant earlier this year and the organ was from a person with AIDS. The recipient is now HIV Positive. The hospital is being sued. These days you have t Continue reading >>

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