
App-controlled Designer Cells Treat Diabetes
Electronic monitoring and storing of health data is all of the rage right now. Many of us track the number of steps we take with our mobile phones or smart watches, log food consumption, and measure our heart rate. But would you trust a mobile health app to decide when you should receive a life saving, but in some cases, life threatening, drug? For diabetics, this possibility is approaching reality. Diabetes is a condition in which the β-cells of the pancreas do not produce sufficient insulin to maintain blood glucose (BG) homeostasis. BG levels that are too high or too low are both dangerous, but for different reasons. The brain needs glucose to function, so with too little glucose, the body starts shutting down and can slip into a coma. Too much glucose in the bloodstream damages nerves and organs—long-term elevated BG levels can lead to kidney damage, neuropathy, and blindness. Glucose enters the bloodstream as the body breaks down food from a meal into simple sugars that cells can use for energy. Insulin stimulates muscle, liver, and fat tissue to take excess glucose out of the blood, and those cells can subsequently use that glucose for normal functioning. Patients with type 1 diabetes (T1D) lack insulin because their β-cells, which produce insulin, have been attacked and killed by an autoimmune reaction. These patients usually develop diabetes early in life and need to inject insulin many times a day. Type 2 diabetics experience high BG levels because their cells have become insulin resistant and no longer properly uptake glucose from the bloodstream, or their β-cells have become stressed out and no longer secrete proper levels of insulin. Type 2 diabetes (T2D) is associated with obesity and physical inactivity. In some cases, T2D can be controlled by diet al Continue reading >>

Caffeine And Type 1 Diabetes
Have you ever noticed a difference in your blood sugar after drinking a big cup of coffee or tea? According to the Mayo Clinic, caffeine can indeed have an affect on your blood glucose levels causing lower or higher fluctuations, so limited consumption is recommended for better control. Another study published by the ADA (2005) suggests that people with Type 1 or Type 2 diabetes can reduce their risk of hypoglycemia during the night by having a small to moderate amount of caffeine before bed. Some people also claim that symptoms of hypoglycemia become more noticeable when incorporating caffeine into their diet. The effects of caffeine on each person are varied though with the added factor of tolerance to the stimulant can build up as quantity increases. While some people claim that they see a noticeable difference in their BG levels when they drink caffeine, others say that they don’t have any issues incorporating caffeine with food. Let’s explore some variables that could contribute to the shift in BG levels in relation to caffeine consumption. Side effects Certain common side effects of caffeine consumption may often explain shifts in BG levels. Lack of sleep Not enough sleep has proven to contribute to insulin resistance in the body for people with Type 1. Too much caffeine could certainly contribute to insomnia, especially since caffeine tolerance decreases as we grow older. Elevated heart rate / “the jitters” Two common effects if too much caffeine is in the system, or if the body is not accustomed to it. These are also symptoms of hypoglycemia, which might cause someone with Type 1 to check their BG levels more frequently if mistaking the symptoms for a low. Heartburn / Upset stomach / Dehydration Some people are less tolerant to coffee and other caffeinat Continue reading >>

What Bg Count Is Important???
Late last year I went to the doctor and found that my A-1 C was a seven. He told me to watch my diet and get some exercise. Being a bit stubborn, I didn't listen. I went back this May and my A-1 C was 12. Yes I know horrible! Since then, I have bought a BG monitor and my blood sugar started out in the 250 range...so I started dieting and exercising. I've been eating low-carb and walking about 3 miles five times a week. In the last two months, my BG has come down to a daily average of 174 and the morning average of 160 (both are 7 day running averages). There is still work to do, but I am not taking medication yet and I continue to exercise and stay on my diet and my blood sugar continues to drop. What is the most important measurement to look at? Is it an average of my morning readings or an overall average of my entire day's readings? Moderator T2 insulin resistant Using Basal/Bolus Therapy Open to interpretation. I say the HbA1c because it usually runs about every 3 months. Average of fasting numbers could be unusually higher because of Dawn Phenomenon. What does your doctor say? Open to interpretation. I say the HbA1c because it usually runs about every 3 months. Average of fasting numbers could be unusually higher because of Dawn Phenomenon. What does your doctor say? He wants it down at seven or below. I'm due to go in for another HBA1C reading in about a month and a half. What is the dawn phenomenon?? What I'd be looking at is the HbA1c as Nan says, so averages are good to watch; but I'd also be examining individual one and two hour post-prandial numbers, and examining the content of my meals carefully for any that are over 140 at one hour and over 120 at two hours. Fine-tuning diet can do a lot to bring overall BG numbers down. HbA1c 1st November 2017 31mmol/mol Continue reading >>

Home - One Drop: Diabetes Management Made Simple
One Drop: Diabetes Management Made Simple Get everything you need, all in one place. One Drop | Mobile empowers you to track and analyze all your diabetes data glucose, medications, food, and activity with just one app. Set goals, track progress, and see results! One Drop | Chrome is a Bluetooth blood glucose monitor that syncs with the One Drop | Mobile app. Get all the test strips you need with a One Drop | Premium or One Drop | Plus subscription. One Drop | Experts is a personal diabetes coaching program designed to help you reach all your health goals. Work with a CDE available 24/7 to get the support you need in real-time. Track all the essentials Blood Glucose, Food, Meds and Activity all in one place. Wirelessly transmit blood glucose data via Bluetooth to the One Drop Mobile app. Get all the test strips you need with a One Drop | Premium or One Drop | Plus subscription. Work one-on-one with your One Drop | Expert, a personal diabetes coach available 24/7 to guide you, support you, and celebrate your accomplishments. One Drop | Experts has been Recognized by the American Diabetes Association for Quality Self-Management Education* and Support. Beautiful visual interface and clear reports that the app can generate for my healthcare provider. Best of all is the news feed articles and community stream where you can see how other users are managing diabetes. Smallest drop of blood! No more entering numbers in my phone! I love it all! This is the app that gets it... Bluetooth blood glucose tracking works perfectly. Medication reminder and tracker in one. . . There is even someone who chats with you and checks up on you. Finally a meter and strips I can afford. Experts are great too.... overall I love it and am totally happy with it!!! Get One Drop | Mobile for free on Continue reading >>

Drugs That Can Raise Bg
By the dLife Editors Some medicines that are used for treating other medical conditions can cause elevated blood sugar in people with diabetes. You may need to monitor your blood glucose more closely if you take one of the medicines listed below. It’s important to note that just because a medicine has the possibility of raising blood sugar, it does not mean the medicine is unsafe for a person with diabetes. For instance, many people with type 2 diabetes need to take a diuretic and a statin to lower blood pressure and cholesterol. In these and many other cases, the pros will almost always outweigh the cons. Don’t ever take matters of medication into your own hands. Discuss any concerns you have with your healthcare provider. Certain Antibiotics Of all the different antibiotics, the ones known as quinolones are the only ones that may affect blood glucose. They are prescribed for certain types of infection. Levofloxacin (Levaquin) Ofloxacin (Floxin) Moxifloxacin (Avelox) Ciprofloxacin (Cipro, Cipro XR, Proquin XR) Gemifloxacin (Factive) Second Generation Antipsychotics These medicines are used for a variety of mental health conditions. There is a strong association between these medicines and elevated blood sugar, and frequent monitoring is recommended. Clozapine (Clozaril) Olanzapine (Zyprexa) Paliperidone (Invega) Quietiapine (Seroquel, Seroquel XR) Risperidone (Risperdal) Aripiprazole (Abilify) Ziprasidone (Geodon) Iloperidone (Fanapt) Lurasidone (Latuda) Pemavanserin (Nuplazid) Asenapine (Saphris) Beta Blockers Beta blockers are used to treat high blood pressure and certain heart conditions. Not all available beta blockers have been shown to cause high blood sugar. Atenolol Metoprolol Propranolol Corticosteroids Corticosteroids are used to treat conditions where th Continue reading >>

Diabetes High Bg - Stickman Communications
VAT is not applicable (Not VAT registered). delivery is additional. Keyring Card reading "I have diabetes. My blood glucose levels are high. Sometimes this happens even though I take good care of my health. I may be tired and irritatble, need to drink lots of water, need the toilet more often and/or change my insulin dose." Laminated, 110x80mm cards, with a hole punched in the top left hand corner to allow attachment to keyring. Colours may vary slightly from colours shown on screen. Cards are sold 'pick and mix' style - choose the cards you want, and they will be sent to you on a plain metal keyring. Stickers for applying to the edge of important cards to enable quick finding are provided free when 5 or more cards are ordered. Compatible with all other Keyring Cards on this site. Photos which include other cards are only to illustrate what a final pack may look like. Laminated, 110x80mm cards, with a hole punched in the top left hand corner to allow attachment to keyring. Colours may vary slightly from colours shown on screen. Cards are sold 'pick and mix' style - choose the cards you want, and they will be sent to you on a plain metal keyring. Stickers for applying to the edge of important cards to enable quick finding are provided free when 5 or more cards are ordered. Compatible with all other Keyring Cards on this site. Photos which include other cards are only to illustrate what a final pack may look like. Continue reading >>

Healthy Lifestyle Programs - Diabetes Wa
Changing your lifestyle isn’t easy, especially if you are trying to make and maintain those changes all by yourself Our structured programs will give you the motivation and support to turn today’s healthy choices into lifelong healthy habits. We run a number of individual, group and workplace programs that will help you to choose a healthy diet, get active and improve your health. My Healthy Balance is a free online program allowing individuals to work through a structured program at their own pace. Read more about My Healthy Balance. SHED-IT it is a program designed specifically to help men achieve sustainable, long-term weight loss. Read more about SHED-IT. The Get on Track Challenge is a free, team-based program. This healthy lifestyle program is designed to help you and your team mates take steps (literally) that will improve your help. Read more about the Get on Track Challenge. Yarn Up is an interactive group session for Aboriginal and Torres Strait Islander communities. These sessions aim to bring your community together to yarn about how serious diabetes is, why your community is at particular risk of this condition, and what you can do to prevent or manage this condition. Read more about Yarn Up . Would you like to subscribe to our e-newsletter? Continue reading >>

About Glucose Curves
The glucose curve is an ideal tool for differentiating the problem of short duration of insulin activity versus Somogyi effect. It helps to determine insulin effectiveness, and the maximum and minimum levels of glycemia, which should ideally be between 100–250 mg/dL (5.6–13.9 mmol/L) for the majority of the day. Try our online glucose curve generator. When creating a glucose curve, remember that stress can affect the reliability of results and the glucose curve is only one tool among others that can help diagnose and monitor canine diabetes mellitus. How to complete a glucose curve Feed and inject the dog with Vetsulin® (porcine insulin zinc suspension) as it is done at home. This may be done by the owner and then verified by the veterinarian. If the dog exercises at home during the day, the same exercise routine should be adhered to while the dog is in the clinic. Blood sampling: Just prior to insulin administration Then, in at least 60 to 120 minute intervals Over a period of 12 hours, ideally for 24 hours How to interpret a glucose curve It helps to determine: Insulin effectiveness. Maximum and minimum glycemia, which should ideally be between 100 and 250 mg/dL (5.6–13.9 mmol/L). Glucose nadir goal: 100–150 mg/dL (5.6–8.3 mmol/L) Duration of insulin action: From the injection to a glycemia of 250 mg/dL (13.9 mmol/L) Goals: Once daily 20 hours; twice daily 10-12 hours Measuring blood glucose Two different options: Collect a venous blood sample from a peripheral vein. Plasma glucose concentrations are measured in the laboratory (“gold standard”). Collect a drop of capillary blood from the ear (pinna), or sometimes the inner lip or elbow callus, and analyze this using a handheld blood glucose meter (glucometer). Glucometers should be calibrated specifical Continue reading >>
- Exercise and Glucose Metabolism in Persons with Diabetes Mellitus: Perspectives on the Role for Continuous Glucose Monitoring
- Postprandial Blood Glucose Is a Stronger Predictor of Cardiovascular Events Than Fasting Blood Glucose in Type 2 Diabetes Mellitus, Particularly in Women: Lessons from the San Luigi Gonzaga Diabetes Study
- Exercise and Blood Glucose Levels

Mood Changes Associated With Blood Glucose Fluctuations In Insulin-dependent Diabetes Mellitus.
Abstract Individuals with insulin-dependent diabetes mellitus (IDDM) and their healthcare practitioners believe that extreme blood glucose (BG) fluctuations are characterized by changes in subjective mood states and emotional behavior, as well as physical symptoms. This study examined relationships between BG levels and self-reported mood in a group of 34 IDDM adults. The method followed a within-subject, repeated-measures design employed in previous studies of physical symptoms associated with diabetic glucose. Four times each day, participants completed a mood/symptom checklist just prior to a self-measurement of BG until 40 checklists had been completed. Half the items on the checklist described physical symptoms and half described mood states. In addition, half the mood items described negative states and half described positive states. Within-subject correlations and regressions showed that moods were related to BG for the majority of participants and that, like physical symptoms, mood-BG relationships were highly idiosyncratic. Low BG levels tended to be associated with negative mood states, primarily self-reported "nervousness." Positive mood items were almost always associated with high BG. High BG levels also frequently correlated with negative mood states, although the negative mood items that tended to relate to high glucose (anger, sadness) differed from those that tended to relate to low BG. The implications of these findings for self-treatment and glucose perception in the IDDM individual are discussed. Continue reading >>
- 5 Causes of Blood Sugar Fluctuations in Diabetes
- PredictBGL is a diabetes management app predicting fluctuations in blood sugar levels
- Postprandial Blood Glucose Is a Stronger Predictor of Cardiovascular Events Than Fasting Blood Glucose in Type 2 Diabetes Mellitus, Particularly in Women: Lessons from the San Luigi Gonzaga Diabetes Study

Replace-bg: A Randomized Trial Comparing Continuous Glucose Monitoring With And Without Routine Blood Glucose Monitoring In Adults With Well-controlled Type 1 Diabetes.
Diabetes Care. 2017 Apr;40(4):538-545. doi: 10.2337/dc16-2482. Epub 2017 Feb 16. OBJECTIVE: To determine whether the use of continuous glucose monitoring (CGM) without confirmatory blood glucose monitoring (BGM) measurements is as safe and effective as using CGM adjunctive to BGM in adults with well-controlled type 1 diabetes (T1D). RESEARCH DESIGN AND METHODS: A randomized noninferiority clinical trial was conducted at 14 sites in the T1D Exchange Clinic Network. Participants were ≥18 years of age (mean 44 ± 14 years), had T1D for ≥1 year (mean duration 24 ± 12 years), used an insulin pump, and had an HbA1c ≤9.0% (≤75 mmol/mL) (mean 7.0 ± 0.7% [53 ± 7.7 mmol/mol]); prestudy, 47% were CGM users. Participants were randomly assigned 2:1 to the CGM-only (n = 149) or CGM+BGM (n = 77) group. The primary outcome was time in range (70-180 mg/dL) over the 26-week trial, with a prespecified noninferiority limit of 7.5%. RESULTS: CGM use averaged 6.7 ± 0.5 and 6.8 ± 0.4 days/week in the CGM-only and CGM+BGM groups, respectively, over the 26-week trial. BGM tests per day (including the two required daily for CGM calibration) averaged 2.8 ± 0.9 and 5.4 ± 1.4 in the two groups, respectively (P < 0.001). Mean time in 70-180 mg/dL was 63 ± 13% at both baseline and 26 weeks in the CGM-only group and 65 ± 13% and 65 ± 11% in the CGM+BGM group (adjusted difference 0%; one-sided 95% CI -2%). No severe hypoglycemic events occurred in the CGM-only group, and one occurred in the CGM+BGM group. CONCLUSIONS: Use of CGM without regular use of confirmatory BGM is as safe and effective as using CGM with BGM in adults with well-controlled T1D at low risk for severe hypoglycemia. © 2017 by the American Diabetes Association. Continue reading >>
- Resist diabetes: A randomized clinical trial for resistance training maintenance in adults with prediabetes
- A Website to Promote Physical Activity in People With Type 2 Diabetes Living in Remote or Rural Locations: Feasibility Pilot Randomized Controlled Trial
- Exercise and Glucose Metabolism in Persons with Diabetes Mellitus: Perspectives on the Role for Continuous Glucose Monitoring

2010 Aaha Diabetes Management Guidelines For Dogs And Cats
Renee Rucinsky, DVM, ABVP (Feline) (Chair) | Audrey Cook, BVM&:S, MRCVS, Diplomate ACVIM-SAIM, Diplomate ECVIM-CA | Steve Haley, DVM | Richard Nelson, DVM, Diplomate ACVIM | Debra L. Zoran, DVM, PhD, Diplomate ACVIM | Melanie Poundstone, DVM, ABVP - Download PDF - Introduction Diabetes mellitus (DM) is a treatable condition that requires a committed effort by veterinarian and client. This document provides current recommendations for the treatment of diabetes in dogs and cats. Treatment of DM is a combination of art and science, due in part to the many factors that affect the diabetic state and the animal's response. Each animal needs individualized, frequent reassessment, and treatment may be modified based on response. In both dogs and cats, DM is caused by loss or dysfunction of pancreatic beta cells. In the dog, beta cell loss tends to be rapid and progressive, and it is usually due to immune-mediated destruction, vacuolar degeneration, or pancreatitis.1 Intact females may be transiently diabetic due to the insulin-resistant effects of the diestrus phase. In the cat, loss or dysfunction of beta cells is the result of insulin resistance, islet amyloidosis, or chronic lymphoplasmacytic pancreatitis.2 Risk factors for both dogs and cats include insulin resistance caused by obesity, other diseases (e.g., acromegaly in cats, hyperadrenocorticism in dogs), or medications (e.g., steroids, progestins). Genetics is a suspected risk factor, and certain breeds of dogs (Australian terriers, beagles, Samoyeds, keeshonden3) and cats (Burmese4) are more susceptible. Regardless of the underlying etiology, diabetic dogs and cats are hyperglycemic and glycosuric, which leads to the classic clinical signs of polyuria, polydipsia (PU/PD), polyphagia, and weight loss. Increased fat mobi Continue reading >>

Do Your Bgs Bounce From Very Low To Very High?
Question: My blood sugars bouce from very high to very low. For example, I can experience a low blood glucose (BG) level of 60, 50, or 43 mg/dl and then two to four hours later my BG skyrockets to 200 to 400 mg/dl? This is called the Somogyi effect or "rebound hypoglycemia". This condition results in high BG levels, and is actually is triggered by low BG levels. It is a natural defense mechanism of the body to regulate itself and counteract episodes of severe hypoglycemia. To keep it simple, we understand that the pancreas produces and regulates insulin and other hormones in response to BG fluctuations from food, activity and stress levels in the body that occur in everyday life. Every action in the body causes a reaction. Insulin is used in the body to metabolize carbohydrate content from food, which is broken down into energy units (glucose/sugars), which is used and stored as fuel. Insulin keeps the BG from rising too high. Other hormones keep us from getting too low. Some of the glucose in our bodies is stored in the liver as glycogen (a form of body glucose). In most people, whenever BG gets too low, certain hormones called counterregulatory hormones kick in and cause the BG level to rise. For example, the liver kicks in stored glycogen as a counterregulatory defense tp keep us from sinking into dangerous levels of hypoglycemia. In people without diabetes, this effect is quickly counteracted by an increase in insulin production, which lowers the glucose released by the liver, and the body self-regulates when the BG is normalized once again. In people with diabetes, when the BG dips too low due to the effects of too much insulin, or glucose depletion from moderate to vigorous exercise, or not enough glucose derived from food metabolism, the liver kicks in stored gly Continue reading >>

Can I Exercise With A High Bg?
I've read that it's not good to exercise with a blood glucose of 250 or higher. Do you still burn calories when you are this high? Sometimes after exercise I'll test and my blood glucose has gone up, and I wonder if my workout was all for nothing. Continue reading >>

The Best Diabetes Apps Of The Year
We’ve selected these apps based on their quality, user reviews, and overall reliability as a source of support for people living with diabetes. If you want to nominate an app for this list, email us at [email protected] The Centers for Disease Control and Prevention (CDC) estimate that type 1, type 2, and gestational diabetes impacts 29 million Americans, about 9 percent of the population. Someone with diabetes may experience complications such as kidney problems, blindness, or heart failure, according to the CDC. The good news is that with increased education, people are recognizing symptoms, like going to the bathroom often, having blurry vision, losing weight, experiencing tingling or numbness in lower limbs, and feeling very thirsty, hungry, or tired. Thanks to earlier diagnoses, improved treatment tools, and better self-care, people are living better with diabetes. Part of that care includes eating healthy foods, exercising, taking medicines like insulin, sticking to your treatment plan, and being proactive about colds and other sicknesses. Keeping all the pieces of your care plan straightforward can be a challenge, but several apps have emerged to help you track your day and your health. While some of these apps are specifically for diabetes and some are geared for general diet, they can all help you take control of your health. Here are this year’s top picks for the best diabetes apps. iPhone rating: ★★★★★ Android rating: ★★★★★ Price: Free Fooducate promises to be your weight loss coach. This app has a grading system designed to help you make smarter choices. It will help you understand the pros and cons of certain foods. In addition to sugar counts, the app helps you monitor carbs, colorings, mood, hunger, sleep, and exercise. R Continue reading >>

Diabetes In Check: Blood Glucose & Carb Tracker 4+
The most comprehensive type 2 diabetes app on the market, designed by a Certified Diabetes Educator. You’ll get all the tools plus the most-up-to-date information you need to control and manage your condition every day. This app is designed to help you 1) LOWER YOUR BLOOD SUGAR 2) GET ACTIVE 3) EAT BETTER 4) COUNT CARBS 5) MANAGE YOUR WEIGHT. √ Featured by Apple as “Best App For Diabetics” √ DIGITAL COACHING: Get in-app support from a Certified Diabetes Educator. √ BLOOD GLUCOSE TRACKING: Enter your BG levels to see how food, exercise, and stress impact your condition. √ MEDICATION TRACKING: Set reminders and trackers to stay compliant, so you keep your BG in control. √ REMINDERS: Never again forget to measure your blood glucose, take your medication, or track your food and exercise. √ CARB TRACKER: Search a database of over 80,000 foods, and see their impact on your BG levels. √ BARCODE SCANNER: Quickly track the carb and nutrition facts for all your packaged foods. √ WHAT TO EAT: Consult the quick reference guide to find out: "Can I eat _____?" √ 100’s OF RECIPES: Enjoy delicious, diabetes-friendly recipes selected for you by a Certified Diabetes Educator. √ PERSONALIZED MEAL PLAN: Get quick and easy daily menus of diabetes-friendly recipes plus a personalized daily plan to help you stay on track and achieve your goals. √ TOOLS TO GET ACTIVE: Set and track exercise goals and stay motivated. √ MESSAGE BOARDS: Join a community of over 200,000 people who are also living with type 2 diabetes. Post your personal questions, share success stories, and find support from people like you. √ DATA THAT’S EASY TO SHARE WITH YOUR DOCTOR: Quickly send your data to your doctor so you can review your progress during your next appointment. This top Continue reading >>
- World's first diabetes app will be able to check glucose levels without drawing a drop of blood and will be able to reveal what a can of coke REALLY does to sugar levels
- Nobody Needs This Silicon Valley-Made Blood Sugar Tracker for 'Wellness' and Lifestyle
- Postprandial Blood Glucose Is a Stronger Predictor of Cardiovascular Events Than Fasting Blood Glucose in Type 2 Diabetes Mellitus, Particularly in Women: Lessons from the San Luigi Gonzaga Diabetes Study