
5 More Benefits Of Adding Bcaa Supplements To Your Pre-workout Meal
5 More Benefits of Adding BCAA Supplements to Your Pre-workout Meal In our last post, we discussed how BCAA supplements can be excellent additions to your pre-workout diet . However, thats not all the benefits you can get from these supplements. BCAA can also help you build up lean muscle groups, and let you reduce body fat percentage safely with time, boosting strength without piling on body weight. Here are 5 More Reasons To Add BCAA Supplements To Your Pre-workout Meal: BCAAs may increase the rate of oxidation of fat in your body, resulting in gradual reduction in body fat percentage with regular intake. This can especially come in handy if you are overweight and are trying to reduce body weight while gaining lean muscle mass. Consuming BCAAs may help reduce muscle soreness and stiffness following high intensity workout, research suggests. Scientists link this to the ability of BCAAs to provide readily usable protein to injured muscles and glycogen to muscles in need of instant energy. The energy provides tired muscles with the boost at the right time, and may help you maintain high intensity workout for quite some time longer than usual. BCAAs may be able to reduce muscle loss associated with aging, research suggests. This may help in preventing cancer as well, by helping in regenerating cells all over the body. BCAA consumption may reduce the risk of developing Diabetes in healthy individuals. Research suggests that BCAAs can improve insulin health and boost metabolic rate. However, diabetics should not consume BCAA, as their bodies are unable to make use of BCAA properly. BCAA is not only pretty ineffective for them, but can also harm them. Research shows that consumption of BCAA may reduce the quantity of cortisol in the bloodstream of the user and improve the a Continue reading >>

Prediabetes And Bcaas
Thanks for taking the time to run this forum. I really appreciate it. I had a fasting blood test at work today and it came back with a serum glucose level of 103mg/dL which I'm told makes me prediabetic. I just laughed it off last year and assumed it would go away but this was my second test result at this level so I guess it's real. I got the usual advice: lose 10lbs, exercise gently 30 minutes a day, cut back on soda, blah, blah. I had been hanging around advanced novice numbers (330/230/400) late last year, then dropped off badly when I went on an extended break over Thanksgiving to Xmas, losing 7lbs and many, many more off the bar. I've been slowly working my way back up the past two months so I'm not particularly impressed with the idea of losing even MORE weight, and even more strength. That said while I'd like to get my squat up to 405lb @180 next year, I also don't want to give myself diabetes in the process. (1) What can I do to address this test result? I'm not sure there's not a lot else I can cut out since I generally don't eat junk, sodas, juices etc. I don't eat a lot of sugar generally. (2) Should try to cut back on my CHOs? Should I be tracking my macros more carefully given this result? At present all I try to track is protein at 180g & keep to around 200g CHO. Fat? No idea. Never cared to think about it. (3) Should I be concerned about the insulin spiking effects of the BCAAs (Leucine in particular)? I have three pulses: mid-morning, mid-afternoon and before sleeping (i.e. basically 2h after eating). On workout days I'll add one first thing in the morning, and another PWO. (4) Given my situation would it be safer to try to cut ~10% BF first (say ~10lbs) and then try to build slowly towards 405lb rather than my original plan of gaining weight quickly t Continue reading >>

Branched-chain Amino Acids And The Association With Type2 Diabetes
Branched-chain amino acids and the association with type2 diabetes Department of Endocrinology, China-Japan Friendship Hospital, Beijing, China Author information Copyright and License information Disclaimer Copyright 2015 The Authors. Journal of Diabetes Investigation published by Asian Association of the Study of Diabetes (AASD) and Wiley Publishing Asia Pty Ltd This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. This article has been cited by other articles in PMC. The prevalence of type 2 diabetes is soaring worldwide and is now recognized as one of the main threats to human health being associated with comorbidities, such as cardiovascular disease. Type 2 diabetes is a condition characterized by abnormalities in carbohydrate, lipid and protein metabolism, with the most characteristic features being hyperglycemia and dyslipidemia. The underlying pathological aberrations comprise insulin resistance and bihormonal dysfunction of the pancreatic - and -cells. As aforementioned, high-protein diets are associated with impaired glucose tolerance, insulin resistance and an increased incidence of type2 diabetes 1 . Protein consists of amino acids (AAs). AAs were traditionally classified as essential or non-essential for humans and animals. Essential AAs cannot be synthesized from other compounds in the body at the level required for normal growth, so they must be obtained from food. Leucine, isoleucine and valine are named as branched-chain amino acids (BCAAs). BCAAs are the most abundant of the essential AAs. Leucine is the most abundant BCAA in Continue reading >>

Is It Safe To Take Supplements If You Have Diabetes?
You will find supplements for anything and everything these days. Even when you do not suffer from an ailment, supplements are suggested to keep you healthy and ailment-free. According to CDC, use of supplements is common among US adult population – over 50% adults used supplements during 2003-2006, with multivitamins/multiminerals being the most commonly used. So when you are a diabetic, especially if you have prediabetes and type-2 diabetes, you may find yourself confronting a large number of options for supplements that claim to support, reduce and even cure your diabetes. Diabetes is quite a frustrating disorder and you may find yourself tempted to try out these supplements one after another. But is it really safe to take supplements when you are a diabetic? Let us find out. But before that you need to understand what exactly supplements are. Defining Supplements As the name suggests, a supplement is anything that adds on to something. A dietary supplement is therefore something that one takes in addition to one’s diet to get proper nutrition. US Congress in the Dietary Supplement Health and Education Act defines dietary supplements as having the following characteristics: It is a product that is intended to supplement the diet; It contains one or more dietary ingredients (including vitamins, minerals, herbs and other botanicals, amino acids, and other substances) or their constituents; It is intended to be taken by mouth as a pill, capsule, tablet, or liquid; It is not represented for use as a conventional food or as sole item of a mean or a diet; and, It is labeled on the front panel as being a dietary supplement. Now let us look at some general benefits and risks of taking supplements. We will discuss these in context of diabetes later in the article. Benefit Continue reading >>

The Relationship Between Branched-chain Amino Acid Related Metabolomic Signature And Insulin Resistance: A Systematic Review
Copyright © 2016 Xue Zhao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Recent studies have shown the positive association between increased circulating BCAAs (valine, leucine, and isoleucine) and insulin resistance (IR) in obese or diabetic patients. However, results seem to be controversial in different races, diets, and distinct tissues. Our aims were to evaluate the relationship between BCAA and IR as well as later diabetes risk and explore the phenotypic and genetic factors influencing BCAA level based on available studies. We performed systematic review, searching MEDLINE, EMASE, ClinicalTrials.gov, the Cochrane Library, and Web of Science from inception to March 2016. After selection, 23 studies including 20,091 participants were included. Based on current evidence, we found that BCAA is a useful biomarker for early detection of IR and later diabetic risk. Factors influencing BCAA level can be divided into four parts: race, gender, dietary patterns, and gene variants. These factors might not only contribute to the elevated BCAA level but also show obvious associations with insulin resistance. Genes related to BCAA catabolism might serve as potential targets for the treatment of IR associated metabolic disorders. Moreover, these factors should be controlled properly during study design and data analysis. In the future, more large-scale studies with elaborate design addressing BCAA and IR are required. 1. Introduction Obesity, one of the escalating global health problems, is a major risk factor for the onset and development of diabetes mellitus, metabolic syndrome, cancer, and other Continue reading >>

Can Bcaas Improve Insulin Health?
| Posted by Stated Nutrition | Supplements | 0 comments | Branched chain amino acids may have a positive impact on insulin health and thus not only improve body composition but can reduce the risk of type 2 diabetes. Before we jump into the specifics, lets back up slightly and discuss insulin and its role in the body Insulin (a hormone) is made in the pancreas and released into the bloodstream when blood glucose levels rise. As weve learned, glucose is a form of sugar in which carbohydrates are degraded into through the digestion process. Glucose is then absorbed in muscle fat and liver cells to be used for energy with the help of insulin. While this description is very high level, the energy generating process is what most people are referring to when metabolism is discussed. Insulin plays a major role in this metabolic process by helping muscle, fat and liver cells to absorb blood glucose, encourage liver and muscle tissue to store glucose in the form of glycogen, and helping to control blood glucose levels by inhibiting liver glucose production. Without insulin, glucose levels rise to unsafe levels leading to major health risks and even death. In a healthy person, these process function normally and would largely go unnoticed throughout your day. However, in some cases insulin resistance can occur inhibiting a lot of the processes insulin is involved in. When insulin resistance occurs, the cells that would usually absorb blood glucose with normal amounts of insulin struggle. This causes the insulin releasing pancreas to push more insulin into the blood than it should need. As this process unfolds time and time again with every carbohydrate is eaten, the increase demand for insulin can cause the pancreas to fall behind leading to type 2 diabetes, pre-diabetes, and ot Continue reading >>

Bcaas & Diabetes - Bodybuilding.com Forums
BCAAs (leucine in particular) is known to activate mTOR, which in turn, increases insulin (up to 220%). Now, could taking BCAAs everyday and chronically stimulating the pancreas to release this large amount of insulin cause insulin resistance? mTOR Inhibition by Rapamycin Prevents -Cell Adaptation: diabetes.diabetesjournals.org/content/57/4/945.full Remember that Rapamycin (diabetes drug) exerts it's action by inhibiting mTOR. However, here's another study that says BCAAs improve insulin resistance: What are your thoughts on this....do you still think BCAAs are safe (15g per day, split pre-, intra- and post-workout)? BCAAs (leucine in particular) is known to activate mTOR, which in turn, increases insulin (up to 220%). Now, could taking BCAAs everyday and chronically stimulating the pancreas to release this large amount of insulin cause insulin resistance? mTOR Inhibition by Rapamycin Prevents -Cell Adaptation: diabetes.diabetesjournals.org/content/57/4/945.full Remember that Rapamycin (diabetes drug) exerts it's action by inhibiting mTOR. However, here's another study that says BCAAs improve insulin resistance: What are your thoughts on this....do you still think BCAAs are safe (15g per day, split pre-, intra- and post-workout)? this is what always bugged me about laynes nortons recommendations for 6 meals a day with a carb + leucine solution inbetween meals.. surely having insulin raised for the whole day with the extra help from the carb + leucine must have negative side effects. although i must admit im not that smart so i could most def be wrong Nice post! I don't have the answer but reps on recharge. Location: Hagerstown, Maryland, United States BCAAs (leucine in particular) is known to activate mTOR, which in turn, increases insulin (up to 220%). Now, could taki Continue reading >>
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Supplements For Diabetics
Diabetes is a condition people face when the body goes throughan abnormally high blood glucose levels. This is caused by a person having a difficult time producing or making use of insulin. The American Diabetes Association shows that you should keep the amount of sugar and saturated fat rather low in you diet. If you are diabetic and also weight lifting, you need to choose the right supplements that fit your dietary needs. Many people take pre-workouts before a workout in order toincreaseenergy and strength. For diabetics, you should choose a pre-workout that is caffeine free. Caffeine may interfere with glucose levels in the body and makes it hard for people to control their blood sugar.You can Build Your Own Stim-Free Pre-Workout on Campusprotein.com to take your workouts to the next level, minusthe added caffeine and stimulants. There are many more benefits for diabetics when it comes to adding protein powder to your diet. Although protein is a great wayto build and maintain muscle, it can also help lower blood glucose levels.Choosing the right protein powder is very important, you want to stay away from oneswith added sugars or fat. Whey isolates will be your best choice, they contain minimal fats and easily digestible protein.Wheyhas theability to boost metabolic rate, improve insulin and blood sugar metabolism, and help maintain appetite that maybenefit many people. Here are some of the best protein options: Continue reading >>

Association Between Plasma Concentrations Of Branched-chain Amino Acids And Adipokines In Japanese Adults Without Diabetes
Association between plasma concentrations of branched-chain amino acids and adipokines in Japanese adults without diabetes Scientific Reportsvolume8, Articlenumber:1043 (2018) | Download Citation Previous studies have consistently reported an association between circulating levels of branched-chain amino acids (BCAAs) or adipokines and insulin resistance; however, the association between BCAA and adipokine levels remains to be clarified. In this cross-sectional study involving 678 participants (435 men) without diabetes, plasma BCAA (valine, leucine, and isoleucine), adipokine (total and high molecular weight [HMW] adiponectin, leptin, and tumor necrosis factor- [TNF-]) concentrations, and an updated homeostasis model assessment of insulin resistance (HOMA2-IR) were measured. The association between the concentrations of total BCAAs and adipokines was adjusted for confounding factors, including body mass index. For the lowest and highest BCAA quartiles, the adjusted geometric mean levels of HMW adiponectin were, respectively, 1.51 and 0.91 g/mL, in men (P for trend < 0.0001); 3.61 and 2.29 g/mL, in women (P = 0.0005). The corresponding geometric mean levels for leptin were 1681 and 2620 pg/mL, in men (P = 0.003), and 4270 and 6510 pg/mL, in women (P = 0.003). Those for HOMA2-IR were 0.89 and 1.11, in men (P < 0.0001), and 0.79 and 0.96, in women (P < 0.0001); no significant association was found with TNF-. These results suggest significant associations between BCAA concentrations and those for adiponectin, leptin and HOMA2-IR in individuals without diabetes. Obesity and metabolic diseases have reached epidemic proportions, globally 1 . To prevent these, the underlying mechanisms of obesity and its related diseases have been investigated. Recently, adipose tissue has st Continue reading >>

Amino Acids And Their Significance For Diabetes
Arginine can reduce insulin resistance Diabetics cannot sufficiently utilise carbohydrates such as sugar, which is an important energy source. Insulin plays a significant role here as it is a blood-sugar reducing endogenous hormone and the production of insulin is lower in those affected. Furthermore, the cells in their bodies are not able to properly absorb the insulin that is available. The reason for this is the highly diminished sensitivity of the cells towards insulin. The cell membranes are unable to recognise the hormone and therefore do not absorb enough of it. The consequence of this so-called insulin resistance is that not enough energy is produced in the cells. Moreover, sugar cannot properly be degraded in the blood and therefore accumulates so that the blood sugar level increases. Over the long-term, a constantly elevated blood sugar level can damage the vessels and lead to calcification and typical resulting illnesses such as stroke or heart attack. Diabetes mellitus type 2 is mostly associated with older people, as the insulin sensitivity in the cells decreases with age. A well-received study from 1998 showed that arginine can reduce insulin resistance, meaning in turn that insulin sensitivity can be increased.1 Arginine - an important amino acid for insulin absorption Another study by European researchers showed that the amino acid arginine is of great importance for the sensitivity of the body’s cells towards insulin. Arginine is a precursor of nitrogen oxide, a transmitting substance which has a direct influence on insulin sensitivity. For the study, six type two diabetes patients were split into two groups. Both groups consumed a normal diabetic diet. One of the groups was administered a placebo to be taken three times daily for one month. The other Continue reading >>

Diabetes Strong's Guide To Workout Supplements (part 2) | Diabetes Strong
Diabetes Strongs Guide To Workout Supplements (Part 2) This is the second part in our series about workout supplements. If you havent read Part 1 yet, I strongly suggest you do that before continuing with this article, as I explain my general approach to supplements in Part 1 and review some of the most common supplements on the market. In this article, I will continue where I left off in Part 1 and review BCAAs, glutamine and pre-workouts (energy boosters) Amino Acids are the building blocks of protein and essential for muscle growth and maintenance (branched chain just refers to their chemical structure). Your body doesnt produce BCAAs by itself, so you need to get them from you diet. The main sources of BCAAs are the high-protein foods that are typically part of a healthy fitness diet anyway (chicken, lean beef, eggs, legumes, protein powder etc.). Because BCAA are effective in stimulating protein synthesis in muscles and preventing muscle breakdown, they are used to treat a number of medical conditions related to protein deficiency or muscle and brain failure. They are also given to people who are confined to their bed for extended periods of time to prevent muscle wasting. Athletes typically use BCAA supplements to increase muscle growth or to maintain muscle mass when dieting to lose weight. While BCAAs are one of the most popular fitness supplements, there is no scientific consensus that they actually have an effect on healthy people who eat a normal or high-protein diet. In general, it seems like you get enough BCAA through your diet that supplementing has a very limited effect at best. The strongest (but not conclusive) evidence of a positive effect from BCAA supplements is on people who want to have a very low body fat percentage while retaining large amounts Continue reading >>

Associations Among Circulating Branched-chain Amino Acids And Tyrosine With Muscle Volume And Glucose Metabolism In Individuals Without Diabetes.
Generate a file for use with external citation management software. Nutrition. 2016 May;32(5):531-8. doi: 10.1016/j.nut.2015.11.003. Epub 2015 Dec 8. Associations among circulating branched-chain amino acids and tyrosine with muscle volume and glucose metabolism in individuals without diabetes. Faculty of Health Science, Suzuka University of Medical Science, Suzuka, Japan; Department of Gastroenterology and Hepatology, Mie University Graduate School of Medicine, Tsu, Japan; Center for Physical and Mental Health, Mie University Graduate School of Medicine, Tsu, Japan. Department of Gastroenterology and Hepatology, Mie University Graduate School of Medicine, Tsu, Japan; Center for Physical and Mental Health, Mie University Graduate School of Medicine, Tsu, Japan. Electronic address: [email protected] Department of Health and Physical Education, Mie University Faculty of Education, Tsu, Japan. Department of Gastroenterology and Hepatology, Mie University Graduate School of Medicine, Tsu, Japan. Center for Physical and Mental Health, Mie University Graduate School of Medicine, Tsu, Japan. Center for Physical and Mental Health, Mie University Graduate School of Medicine, Tsu, Japan; Yokkaichi-Hazu Medical Center, Japan Community Healthcare Organization, Yokkaichi, Japan. Amino acid metabolites, including branched-chain amino acids (BCAA) and tyrosine (Tyr), affect glucose metabolism. The effects of BCAA on insulin resistance in patients with diabetes seem to conflict with mechanisms determined in animal models and cultured cells. The aim of this study was to clarify the controversy surrounding the effects of BCAA by investigating the physiological effects of BCAA and Tyr on glucose metabolism in healthy community dwellers. We investigated associations among BCAA and Continue reading >>
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Recommended Weight Lifting Supplements For Diabetics
Diabetes is a medical condition in which you experience abnormally high blood glucose levels because your body has trouble producing or using insulin. The American Diabetes Association explains that you should limit saturated fat intake and keep sugar intake low, as that can rapidly increase your blood sugar levels. Because many weight lifting supplements contain both of these nutrients, you need to choose supplements carefully and consult a doctor before using any. Many protein bars are high in saturated fat and sugar to overcome the taste of healthy ingredients. However, there are some low-fat, low-sugar protein bars available that may not significantly impact your blood glucose levels. Protein bars such as Doctor's CarbRite Diet bars and Allmax Isofemme bars, which have 6 g or less of fat and 1 g or less of sugar per bar, may support weight lifting because they are high in protein. Both bars use sugar alcohols, which provide fewer calories than sugar and don't cause quick increases in your blood sugar levels. Weight gainers are high-calorie, high-protein supplements that come in powdered form. Unfortunately, many of these weight gainers use sugar and fat to increase the calorie content. Try to find weight gainers that provide fiber and have low sugar and low fat content, such as Cytosport Cytogainer. This supplement contains only 7 g of sugar, 6 g of fat and 4 g of fiber in each 570-calorie serving. Protein powders tend to contain between 100 and 200 calories per serving, and offer primarily protein and much fewer grams of fat and carbohydrates than weight gainers. However, these powder still may contain added sugars and saturated fat. For this reason, you may want to choose a whey protein isolate, a type of protein powder with very little fat and at least 90 percent Continue reading >>

Amino Acid Supplements May Offer Diabetes Hope: Mouse Data
Amino acid supplements may offer diabetes hope: Mouse data Related tags: Glucose metabolism , Diabetes mellitus , Insulin Supplementation with the amino acid arginine could help to improve glucose metabolism by as much as 40%, according to new research in mice. The study shows that supplementation with the amino acid significantly improves glucose metabolism in both insulin-sensitive and insulin-resistant mice. Led by Christoffer Clemmensen from the University of Copenhagen, the researchers suggested that supplementation with the amino acid could offer significant benefits for people who suffer from type 2 diabetes. "We have demonstrated that both lean and fat laboratory mice benefit considerably from arginine supplements," said Clemmensen. "We improved glucose metabolism by as much as 40% in both groups," he said. "In fact, the amino acid is just as effective as several well-established drugs for type 2 diabetics." However the researcher noted: "You cannot, of course, cure diabetes by eating unlimited quantities of arginine-rich almonds and hazelnuts. However, our findings indicate that diet-based interventions with arginine-containing foods can have a positive effect on how the body processes the food we eat." The researchers noted that more than 371 million people worldwide suffer from diabetes, of whom 90% are affected by lifestyle-related diabetes mellitus type 2 (type 2 diabetes). To test the effect of the amino acid arginine, researchers subjected lean and obese animal models to a so-called glucose tolerance test, which measures the body's ability to remove glucose from the blood over time. They found that arginine improves glucose metabolism significantly in both lean (insulin-sensitive) and obese (insulin-resistant) mice. "We can also see that arginine increas Continue reading >>

Effects Of Branch Chain Amino Acids On Glucose Tolerance In Obese Pre-diabetic Subjects (bcaa)
Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More Information Branching chain amino acids (BCAA) have both beneficial and detrimental effects of on metabolism have been established and therefore warrants further investigation. In the preliminary study, the investigators found that BCAAs enhanced glucose metabolism in lean mice while they promoted glucose intolerance in obese mice. In lean mice, BCAAs decreased adiposity and enhanced glucose utilization and insulin sensitivity in different tissues. But in obese mice, BCAAs' effects were mediated by impaired insulin signaling in fat tissue. This study will examine 10 obese subjects with pre-diabetes and examine the effects of taking BCAA supplement and will monitor the subjects blood glucose, insulin, triglyceride levels and will have an oral glucose tolerance test on repeated occasions to see if any changes are noted in their glucose regulation. Dietary Supplement: BCAA High Protein supplement Dietary Supplement: BCAA Low Protein supplement Branched-Chain Amino Acids (BCAAs, including leucine, isoleucine, and valine) regulate multiple cellular functions as nutrient signaling. For example, BCAAs regulate insulin and glucagon secretion and thus glucose metabolism1. BCAAs, especially leucine, is one key regulator of mTOR signaling, which is the central component of a complex signaling network of insulin signaling, cell growth, and proliferation. BCAAs also regulate protein synthesis and degradation in various tissues. Increasing dietary uptake of BCAAs improved the parameters associated with obesity and T2DM, such as body composition and glycemia levels. However, these beneficial effects are not conclusive. Moreover, other studies have shown that circula Continue reading >>
- Early-onset and classical forms of type 2 diabetes show impaired expression of genes involved in muscle branched-chain amino acids metabolism
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