diabetestalk.net

Alternative Therapies Useful In The Management Of Diabetes: A Systematic Review

Alternative Therapies Useful In The Management Of Diabetes: A Systemic Review

Alternative Therapies Useful In The Management Of Diabetes: A Systemic Review

Diabetes mellitus is a metabolic disorder in the endocrine system. This dreadful disease is found in all parts of the world and becoming a serious threat of mankind health. There are lots of chemical agents available to control and to treat diabetic patients, but total recovery from diabetes has not been reported up to this date. In addition to adverse effects, drug treatments are not always satisfactory in maintaining euglycemia and avoiding late stage diabetic complications. Alternative to these synthetic agents, plants provided a potential source of hypoglycemic drugs and are widely used in several traditional systems of medicine to prevent diabetes. Several medicinal plants have been investigated for their beneficial effect in different type of diabetes. Other alternative therapies such as dietary supplements, acupuncture, hydrotherapy, and yoga therapies less likely to have the side effects of conventional approaches for diabetes. Do you want to read the rest of this article? ... Essential oils commonly reported in the literature for neuropathic pain management include lavender, eucalyptus, rosemary, chamomile, and geranium ( Li, 2010). One report emphasized that essential oils, when mixed in the recommended ratios, could help in reducing certain side effects experienced by diabetic patients, such as loss of skin integrity, increased blood glucose, stress, and anxiety ( Pandey, Tripathi, Pandey, Srivatava, & Goswami, 2011). One randomized controlled study examined the impact of topical aromatherapy on patients with diabetes, reporting a decrease in neuropathic pain scores after 4 weeks of treatment ( Motilal & Maharaj, 2013). ... Continue reading >>

Challenges In Systematic Reviews Of Complementary And Alternative Medicine Topics Free

Challenges In Systematic Reviews Of Complementary And Alternative Medicine Topics Free

Article, Author, and Disclosure Information Author, Article, and Disclosure Information Disclaimer: The authors of this article are responsible for its contents. No statement in this article should be construed as an official position of the Agency for Healthcare Research and Quality, the National Center for Complementary and Alternative Medicine, the Office of Dietary Supplements, the National Institutes of Health, or the U.S. Department of Health and Human Services. Acknowledgments: The authors thank Dr. Terry Klassen for feedback on the manuscript, Di Valentine and Cony Rolon for their assistance, and Marilyn Josefsson for administrative support. Grant Support: This research was performed by the Southern California Evidence-based Practice Center based at RAND, Santa Monica, California, with assistance from the University of Alberta Evidence-based Practice Center at Edmonton, Alberta, Canada, under contract with the Agency for Healthcare Research and Quality (contract 290-02-0003) and is based on work originally supported by the National Center for Complementary and Alternative Medicine and the Office of Dietary Supplements, both at the National Institutes of Health. Dr. Shekelle was a Senior Research Associate of the Veterans Affairs Health Services Research and Development Service. Potential Financial Conflicts of Interest: Authors of this paper have received funding for Evidence-based Practice Center reports. Requests for Single Reprints: Paul G. Shekelle, MD, PhD, RAND Corporation, 1776 Main Street, Santa Monica, CA 90401; e-mail, [email protected] . Current Author Addresses: Dr. Shekelle and Ms. Suttorp: RAND Corporation, 1776 Main Street, Santa Monica, CA 90401. Dr. Morton: RTI International, 3040 Cornwallis Road, PO Box 12194, Research Triangle Park, NC 2 Continue reading >>

Vanadium: Diabetes Therapy

Vanadium: Diabetes Therapy

Vanadium is normally mined as a silvery metal. It is useful in non-medical situations because it does not corrode easily. About eighty percent of vanadium mined is used as part of a steel additive. Alloys containing vanadium are extremely touch and are used for various kinds of tools, crankshafts, piston rods, axles, and armor plating. Vanadium alloys are also used in nuclear reactors because the substance absorbs neutrons at a very low rate. Vanadium is found to be an essential nutrient in some species of animals, including humans; however, the research on vanadium in humans is lacking. It is known that humans need very little vanadium for biological purposes. The usual amount of vanadium taken in per day is about 0.01 milligrams daily, which seems to suffice for most biochemical processes found in humans. Too much vanadium has been found to be toxic. Vanadium Use in Animal Studies Vanadium tungstate was given in one animal studies to young male Zucker diabetic fatty rats, which are rats that showed moderate hyperglycemia as part of their pathophysiology. When given to these diabetic rats, vanadium tungstate was found to lower the glucose level to normal levels after taking the substance for about ten days. After the substance was drawn, the glucose levels in these rats were found have elevated glucose levels again, although the glucose levels didn’t rise to the level they were before taking the vanadium tungstate. Rats who were not treated with vanadium tungstate had increasing blood glucose levels throughout the study, reaching levels of up to 450 mg/dL. This high level of glucose was maintained throughout the study. In addition, tolerance to being given glucose into the peritoneum improved in rats given vanadium tungstate but not in those who were untreated. The t Continue reading >>

Alternative Therapies Useful In The Management Of Diabetes: A Systematic Review - Part 4

Alternative Therapies Useful In The Management Of Diabetes: A Systematic Review - Part 4

Alternative Therapies Useful in the Management of Diabetes: A Systematic Review - Part 4 Alternative Therapies Useful in the Management of Diabetes: A Systematic Review - Part 4 By: VitalityLink Finder Wednesday, 21 March 2012 09:38 Awanish Pandey,Poonam Tripathi,Rishabh Pandey,Rashmi Srivatava,and Shambaditya Goswami Department of Pharmacy, Institute of Technology and Management, Gorakhpur, Uttar Pradesh, India. The electronic version of this article is the complete one and can be found online at: Copyright : International Journal of Yoga This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike Unported which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Alternative therapies with antihyperglycemic effects are increasingly sought by patient with diabetes. This comes as no surprise since alternative treatments have been most widely used in chronic disease, which may be only partially alleviated by conventional treatment. Herbal medications are the most commonly used alternative therapy for blood sugar control. Scientific validation of several Indian plant species has provided the efficacy of the botanicals in reducing the sugar level. However, their safely and efficacy need to be further evaluated by well designed, controlled clinically because various non-standardized forms of the herbs have been used for the testing material, the result have been difficult to replicate; therefore, preparations of standardized medicinal herbs is urgently needed in future studies and therapies. Several dietary supplements have been found to benefit people with diabetes, either because of potential or because of the beneficial effect on glucose metaboli Continue reading >>

Adherence To Yoga And Its Resultant Effects On Blood Glucose In Type 2 Diabetes: A Community-based Follow-up Study Angadi P, Jagannathan A, Thulasi A, Kumar V, Umamaheshwar K, Raghuram N - Int J Yoga

Adherence To Yoga And Its Resultant Effects On Blood Glucose In Type 2 Diabetes: A Community-based Follow-up Study Angadi P, Jagannathan A, Thulasi A, Kumar V, Umamaheshwar K, Raghuram N - Int J Yoga

Diabetes mellitus (DM) is a chronic hyperglycemic condition due to insulin resistance or relative insulin deficiency or sometimes both. Although this is usually an irreversible disease, people with diabetes can lead a normal life by correcting their lifestyle. [1] Ayurveda texts mention how lifestyle is responsible for "prameha" which is equivalent of DM. [2] , [3] For Type 1 DM, the main etiological factors are genetic and environmental; however, etiologies of Type 2 DM are many including environmental factors, autoimmunity, genetic factors, insulin resistance, obesity, high body mass index, malnutrition in utero, physical inactivity, and newer hormones. [4] In the last decade, research has shown that alternative therapies such as herbs and dietary supplements, acupuncture, hydrotherapy, and yoga therapy are beneficial for treatment of diabetes and have lesser side effects than western medicine. [5] , [6] , [7] Yoga especially has been observed to prevent and treat diabetes through the practice of healthy diet and lifestyle which in turn balances the endocrine system, massages and tones up the abdominal organs, stimulates the nervous and circulatory systems, and reduces stress. [8] The efficacy of yoga as an intervention however depends heavily on the participants' adherence to yoga regime for the prescribed period of therapy. Studies have depicted the importance of adherence to yoga in bringing about positive changes in outcome parameters and other factors such as greater confidence and ability to perform the yoga exercises in class. [9] , [10] , [11] , [12] Researchers have also opined that "decreased adherence to yoga has the potential to decrease the effect of the intervention because subjects who might sustain the greatest benefit will receive a lower dose of the Continue reading >>

Alternative And Complementary Medical Remedies To Treat T2d

Alternative And Complementary Medical Remedies To Treat T2d

Yoga is a spiritual, physical, and mental discipline developed in India thousands of years ago. It involves exercise, relaxation, breath control, and healing, with origins in Indian philosophy. Yoga may have been practiced as long ago as 5,000 years, but the first known work describing the practice was the Yoga Sutras, written over 2,000 years ago.3 Several studies have been conducted to evaluate the effects of the regular practice of yoga on diabetes control. In one randomized controlled study conducted in 123 adults with type 2 diabetes, yoga plus standard care was compared to standard care alone. The group of patients who took part in yoga in addition to standard treatments had significantly greater improvements in glycemic control (non-fasting blood glucose, hemoglobin A1C levels ) and body weight compared with patients who received only standard treatments. Another randomized controlled study comparing a yogic breathing practice plus standard treatment with standard treatment alone in a group of 49 patients with type 2 diabetes found that the combination resulted in an insignificant trend towards greater improvement in glycemic control, however, significant improvements in quality of life measurements, including physical, psychological and social functioning. Further research is needed to confirm these potential benefits of yoga in patients with type 2 diabetes.1 Meditation has been practiced in various forms for thousands of years, with many techniques developed within the worlds religions, including Hindu, Buddhist, and Judeo-Christian traditions. Meditation has become very popular and is often practiced apart from any religious tradition and is used widely in healthcare settings. Meditation is also an integral part of other alternative medicine systems, includi Continue reading >>

The Metabolic Syndrome And Mind-body Therapies: A Systematic Review

The Metabolic Syndrome And Mind-body Therapies: A Systematic Review

Center for the Study of Complementary and Alternative Therapies, University of Virginia School of Nursing, P.O. Box 800782, Charlottesville, VA 22908-0782, USA Received 22 December 2010; Accepted 18 March 2011 Copyright 2011 Joel G. Anderson and Ann Gill Taylor. This is an open access article distributed under the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The metabolic syndrome, affecting a substantial and increasing percentage of the worldwide population, is comprised of a cluster of symptoms associated with increased risk of type 2 diabetes, cardiovascular disease, and other chronic conditions. Mind-body modalities based on Eastern philosophy, such as yoga, tai chi, qigong, and meditation, have become increasingly popular worldwide. These complementary therapies have many reported benefits for improving symptoms and physiological measures associated with the metabolic syndrome. However, clinical trial data concerning the effectiveness of these practices on the syndrome as a whole have not been evaluated using a systematic and synthesizing approach. A systematic review was conducted to critically evaluate the data from clinical trials examining the efficacy of mind-body therapies as supportive care modalities for management of the metabolic syndrome. Three clinical trials addressing the use of mind-body therapies for management of the metabolic syndrome were identified. Findings from the studies reviewed support the potential clinical effectiveness of mind-body practices in improving indices of the metabolic syndrome. The last 50 years have seen a dramatic increase in metabolic disorders, including obesity and type 2 diabetes, with the number of ind Continue reading >>

Treatments For Gestational Diabetes: A Systematic Review And Meta-analysis

Treatments For Gestational Diabetes: A Systematic Review And Meta-analysis

Abstract Objective To investigate the effectiveness of different treatments for gestational diabetes mellitus (GDM). Methods Data sources were searched up to July 2016 and included MEDLINE and Embase. Randomised trials comparing treatments for GDM (packages of care (dietary and lifestyle interventions with pharmacological treatments as required), insulin, metformin, glibenclamide (glyburide)) were selected by two authors and double checked for accuracy. Outcomes included large for gestational age, shoulder dystocia, neonatal hypoglycaemia, caesarean section and pre-eclampsia. We pooled data using random-effects meta-analyses and used Bayesian network meta-analysis to compare pharmacological treatments (ie, including treatments not directly compared within a trial). Results Forty-two trials were included, the reporting of which was generally poor with unclear or high risk of bias. Packages of care varied in their composition and reduced the risk of most adverse perinatal outcomes compared with routine care (eg, large for gestational age: relative risk0.58 (95% CI 0.49 to 0.68; I2=0%; trials 8; participants 3462). Network meta-analyses suggest that metformin had the highest probability of being the most effective treatment in reducing the risk of most outcomes compared with insulin or glibenclamide. Conclusions Evidence shows that packages of care are effective in reducing the risk of most adverse perinatal outcomes. However, trials often include few women, are poorly reported with unclear or high risk of bias and report few outcomes. The contribution of each treatment within the packages of care remains unclear. Large well-designed and well-conducted trials are urgently needed. This is an Open Access article distributed in accordance with the terms of the Creative Common Continue reading >>

Medical Students Knowledge And Perceptionregarding Complementary And Alternative Medicineused In Dyslipidemia And Diabetes Treatment

Medical Students Knowledge And Perceptionregarding Complementary And Alternative Medicineused In Dyslipidemia And Diabetes Treatment

Medical Students Knowledge and PerceptionRegarding Complementary and Alternative Medicineused in Dyslipidemia and Diabetes Treatment Firdous Jahan 1 * , Muhammad A Siddiqui 2 and Harshini Asogan 3 1 Department of Family Medicine, Oman Medical College, Sohar, Oman 2 School of Health Sciences, Queen Margaret University Edinburgh, UK Associate Professor/Head of the DepartmentFamily Medicine Oman Medical College, Sohar Sultanateof Oman Submitted date: September 30, 2016; Accepted date: October 21, 2016; Published date: October 28, 2016 Visit for more related articles at Diversity & Equality in Health and Care Objective: The aims of this study are to estimate the self-perceived competence knowledge, attitude and practice (KAP) regarding complementary and alternative medicine to control of dyslipidemia and diabetes in medical student, to determine the influence demographic and socioeconomic factors on the level of KAP. Background: Complementary and alternative medicine (CAM) is used in health care and is rapidly evolving. CAM are not presently considered to be part of conventional medicine but frequently used by patients as self-medication and prescribed by health care provider in diabetes and dyslipidemia. Medical students knowledge regarding CAM used in diabetes and dyslipidemia is imperative to handle this in patient care. Method: A cross sectional survey based study conducted at Oman medical college. Students in clinical years were requested to participate. Data was collected with selffilled questionnaire asked about their attitudes and beliefs regarding use of CAM used in dyslipidemia and diabetes. Data was analyzed using Statistical Package for Social Sciences (SPSS) version 20. Results: A total of 101 medical students participated 18 (17.8%) were male and 83 (82.2%) w Continue reading >>

Alternative Therapies Useful In The Management Of Diabetes: A Systematic Review

Alternative Therapies Useful In The Management Of Diabetes: A Systematic Review

Go to: Pathophysiology and Complication Diabetes is known to have a strong genetic component with contributing environmental determinants. Although the disease is heterogynous, there appear to be a fairly consistent phenotype once the disease is fully manifested. Whatever the pathogenic cause the early stage of diabetes is characterized by resistance insulin, targeting tissue mainly in liver, skeletal muscle, and adipocytes. Insulin resistance in the tissue is associated with excessive glucose production by the liver and impaired glucose utilization by peripheral tissue, especially muscle.[4–6] Most of the food we eat is broken down into simply sugar called glucose. The glucose is the main source of fuel to get energy for the body. After digestion, the glucose reaches our blood stream, where it is available for body cells to utilize for energy, but insulin is needed for glucose to get into cells. Insulin is a hormone secreted by the pancreas to transport glucose from blood into different cells of the body. If the pancreas does not produce enough insulin or the produced insulin does not work properly, the glucose cannot enter the body cells. So glucose stay in blood cells which makes the blood sugar level high.[7,8] Thus the body losses the main source of fuel for the energy even though the blood contain high amount of glucose. Since glucose is not metabolized, high amount of glucose circulate in blood, kidney remove extra sugar from blood and excrete it in the urine.[9] Since body does not utilize glucose, the body is under constant impression of hunger that's why in diabetes appetite increases and patient eat more frequently. With increased insulin secretion to compensate for insulin resistance, base line blood glucose level can be maintained with in the normal range Continue reading >>

Complementary Alternative Therapies For Hypertension: Is It Worth It?

Complementary Alternative Therapies For Hypertension: Is It Worth It?

class com.aha.ucm.component.cis.TagListPageData=[,docNativeURL=null,docName=UCM_451496,docStatus=RELEASED,dOutDate=null,docSSFileName=UCM_451496_Complementary-Alternative-Therapies-for-Hypertension-Is-It-Worth-It.jsp,docTitle=Complementary Alternative Therapies for Hypertension: Is It Worth It?,xWebsites=professional,dDocAuthor=t-tim.munoz,xNextReviewDate=10/18/2016 3:02 PM,xTier1=36,xFeaturedItem=No,xElectronicRegistration=No,UserLocale=null,xSubCategory=,dpEvent=null,xComments=AHA Science News commentary forBeyond Medications and Diet: Alternative Approaches to Lowering Blood Pressure,NoHttpHeaders=null,UserTimeZone=null,xRegionDefinition=GENERIC_RD_COL_1,xVideoRenditions=,xSnippetItem=,xNotes=autoconverted |,UserDateFormat=null,encodeDocUrl=null,isDocProfileDone=null,xKeywords=commentary, science news, blood pressure, cardiovascular diseases, complementary therapies, hypertension, prehypertension, preventive medicine,xTier2=,refreshSubMonikers=null,xEditorStepReassignedUsers=null,xLinkTextToDisplay=,dDocAccount=WCM/SOP/SMD,xEndDateTime=null,xClbraAliasList=null,ClientEncoding=null,xCpdIsLocked=0,xUsageRightsDate=null,xModifyDate=02/26/2016 2:26 AM,xTier3=,xEventDate=null,dSubscriptionType=null,xCopyright=No,xPackagedConversions=,dSubscriptionAlias=null,xStorageRule=,dpName=null,xDepartment=Science Operations,dStatus=RELEASED,dPublishType=,xCopyrightDetails=,xSubType=64,isDocProfileUsed=null,xWebsiteObjectType=Data File,xWebFlag=,xSeeAlsoLinks=,xClbraUserList=null,xPartitionId=,xCpdIsTemplateEnabled=0,xLinkWebAddress=,xDontShowInListsForWebsites=,xStartDateTime=null,dInDate=11/04/2015 3:27 PM,xWebsiteSection=professional:1463,dDocName=UCM_451496,dpAction=null,dRevLabel=8,dSecurityGroup=AHAMAH-Public,xCategory=,refreshMonikers=null,xDamConversionType=,dDocFormats=null Continue reading >>

An Update On Natural Compounds In The Remedy Of Diabetes Mellitus: A Systematic Review

An Update On Natural Compounds In The Remedy Of Diabetes Mellitus: A Systematic Review

An update on natural compounds in the remedy of diabetes mellitus: A systematic review Author links open overlay panel HiraChoudhurya Open Access funded by Center for Food and Biomolecules, National Taiwan University Herbal medicine, phytomedicine or botanical medicine are synonymous, utilizes plants intended for medicinal purposes. Medicinal use of herbal medicine in the treatment and prevention of diseases including diabetes has a long history compared to conventional medicine. Diabetes is one of the major public health concerns over the world. Diabetes or hyperglycemia is considered to be one of the common public health hazard; optimal control of which is still not possible. Persistent hyperglycemia or uncontrolled diabetes has the potential to cause serious complications such as kidney disease, vision loss, cardiovascular disease, and lower-limb amputations which contributed towards morbidity and mortality in diabetes. There are various approaches to treat and prevent diabetes as well as its secondary complications, one of it is herbal medicines. However, the selection of herbs might depends on several factors, which include the stage of progression of diabetes, types of comorbidities that the patients are having, availability, affordability as well as the safety profile of the herbs. This review focuses on the herbal and natural remedies that play the role in the treatment or prevention of this morbid disorder diabetes, including their underlying mechanisms for the blood glucose-lowering property and the herbal products already been marketed for the remedial action of diabetes. Continue reading >>

Top 5 Alternative Diabetes Therapies: Are Patients Undermining Their Treatment?

Top 5 Alternative Diabetes Therapies: Are Patients Undermining Their Treatment?

Top 5 Alternative Diabetes Therapies: Are Patients Undermining Their Treatment? Patients with diabetes are turning to unregulated and understudied supplements, foods, and other alternative treatments. Although some may prove useful, others carry risk of real harm. Many individuals with diabetes are turning to home remedies and alternative treatments in an attempt to mitigate their chronic illness or prevent complications.1 Older adults are particularly at risk from unscrupulous schemes and fraudulent health claims.2 The long history of food and herbal diabetes treatments in many cultures, combined with a general rise in the use of complementary and alternative medicine (CAM) over the last few decades makes it likely that many patients are trying one or more of these remedies.3 The popularity of herbal remedies, supplements, and food "cures" certainly doesn't guarantee their safety.1 Adverse effects and interactions are possible, and patients on insulin or secretagogues (such as sulfonylureas and glinides) are at increased risk for hypoglycemia when using CAM therapies.3 A 2017 study found higher CAM use resulted in lower quality of life in people with type 2 diabetes, possibly as a result of the negative effects of using multiple therapies and their interactions with conventional care. Additionally, diabetes patients using CAM showed decreased adherence to prescribed medications.3 Complementary and alternative treatments can take the form of foods, herbal remedies, supplements, activities, or even illegally marketed diabetes drugs. Below is a detailed description of a popular choice in each of these categories. Various foods are purported to help with blood sugar control. Many, such as bitter melon or prickly pear cactus (nopal), are used in traditional medicine. While Continue reading >>

Pandey, A., Tripathi, P., Pandey, R., Srivatava, R. And Goswami, S. (2011) Alternative Therapies Useful In The Management Of Diabetes A Systematic Review. Journal Of Pharmacy & Bioallied Sciences, 3, 504-512. - References - Scientific Research Publishing

Pandey, A., Tripathi, P., Pandey, R., Srivatava, R. And Goswami, S. (2011) Alternative Therapies Useful In The Management Of Diabetes A Systematic Review. Journal Of Pharmacy & Bioallied Sciences, 3, 504-512. - References - Scientific Research Publishing

JOURNAL NAME: Journal of Diabetes Mellitus , Vol.6 No.1 , February 4, 2016 ABSTRACT: Context: Bitter melon (Momoradica charantia) is one of thewell-known plants used for lowering blood glucose since antiquity. Aims: To compare the efficacy and safetyof PDM011011 capsule (1200 mg/day) withMetformin (1000 mg/day) in a 15 weeks study using mean change in fasting plasmaglucose (FPG) and Hb1Ac% in subjects with type 2 diabetes mellitus (T2DM). Settings and Design: This is an open-label,randomized, active-controlled, multicentric, phase III study. Methods and Material: A total of 123eligible patients were randomized in 2:1 ratio in PDM011011 and Metformin arm.Total 83 subjects received PDM011011 capsule (1200 mg/day) and 40 subjectsreceived Metformin (1000 mg/day) in their respective arms for 15 weeks.Subjects were analyzed for FPG and Hb1Ac% at baseline and during treatmentvisits (Visit 3 to Visit 7). Safety assessments were carried out. Results: In this study, the significantreduction in mean FPG level was observed after treatment with PDM011011 capsuleand Metformin in T2DM patients. The mean change from baseline to week 15 in FPGwas 14.52 mg/dL (95% CI: 6.36, 22.67) in the PDM011011-treated subjects and28.34 mg/dL (95% CI: 21.35, 35.32) in the Metformin-treated subjects. At week15, the mean change from baseline in HbA1c levels was 0.27% (95% CI: 0.06,0.47) in the PDM011011 arm and 0.62% (95% CI: 0.40, 0.83) in the Metformin arm. Conclusion: PDM011011 capsule (1200 mg/day)exhibited the modest efficacy and safety as compared to Metformin (1000 mg/day)in type 2 diabetes patients. Continue reading >>

The Use Of Complementary And Alternative Medicines (cams) In The Treatment Of Diabetes Mellitus: Is Continued Use Safe And Effective?

The Use Of Complementary And Alternative Medicines (cams) In The Treatment Of Diabetes Mellitus: Is Continued Use Safe And Effective?

The use of Complementary and Alternative Medicines (CAMs) in the treatment of diabetes mellitus: is continued use safe and effective? Medagama and Bandara; licensee BioMed Central Ltd.2014 Diabetes mellitus is a major cause of morbidity and mortality worldwide, with a prevalence of 347 million in 2013. Complementary and Alternative Medicines (CAM) are a group of remedies that is fast gaining acceptance among individuals. Cinnamon, Bitter gourd (Momordica charantia) and Fenugreek (Trigonella foenum-graecum) are 3 widely used CAMs used worldwide for the treatment of diabetes. Data on safety and efficacy is limited, but the consumption is wide. Crepe ginger (Costus speciosus) and Ivy gourd (Coccinia grandis) are 2 plants used widely in the Asian region for their presumed hypoglycaemic properties. In this review, we analyzed the available evidence for the 5 CAMs mentioned above in terms of in-vitro studies, animal studies sand clinical trials. We also describe the mechanisms of hypoglycaemia and safety concerns where there is available evidence. Clinical trials that studied the hypoglycaemic effects of Cinnamon, bitter gourd, fenugreek and ivy gourd showed conflicting results. Direct comparison between studies remains a challenge in view of the baseline heterogeneity of subjects, differences in substrate preparation, variable end points and poor trial design. Short durations of study and small number of subjects studied is universal. Crepe ginger has not been studied adequately in humans to draw conclusions. In view of the high prevalence of use and safety and efficacy issues, there is an urgent need to study their hypoglycaemic and adverse effects in well-designed long-term clinical trials. Complementary and Alternative Medicine (CAM)Type 2 diabetes mellitusCinnamon (Cinn Continue reading >>

More in diabetes