Allergic Reaction To Metformin
Diabetes Forum The Global Diabetes Community Find support, ask questions and share your experiences. Join the community Discussion in ' Metformin/Biguanides ' started by dawnmc , Sep 13, 2016 . I do have dodgy skin, in that I react to cosmetics and stuff. But recently I have had the most incredible itchy hives. On Dr Google one of the side affects is hives. My GP says no such thing. Has anyone else had a reaction to it, and is there anything I can take instead of Met? I've stopped taking it and my skin clears, literally one tablet and a short time later my skin complains with huge bumps and itching. In your shoes I'd be trusting your body rather than your doctor Do you need medication - have you tested to see how your BG reacts without it? Whatever the reason you have demonstrated that your skin is reacting to something in the prescribed tablets, it may not be the metformin to blame for your reaction, it may be one of the fillers that is used to make the tablet. If you can no longer control bg with diet and exercise perhaps a different type or brand of metformin tablet would be the answer. Its Bolamyn SR 500 mg, I've been on these before and for a while, think I will check out whats in them. Just reading the precautions on their website, very rare 1 in 10000 - hives. Seems I might be that one. metformin is my worse enemy I hate it never felt has ill as I do now. Just reading the precautions on their website, very rare 1 in 10000 - hives. Seems I might be that one. I'm afraid I don't trust the figures they give in any PIL. My mistrust began with statins where 1 in 10000 were supposed to get a reaction as I did except that a bloke up the road got them as well. An amazing coincidence. I do have dodgy skin, in that I react to cosmetics and stuff. But recently I have had th Continue reading >>
Go to: Discussion Metformin is a commonly used antidiabetic drug. The drug is considered to be safe and effective. It is particularly indicated for use in obese patients, with a metabolic syndrome[4,5] It is usually considered as a safe drug. The most common adverse effect of metformin is gastrointestinal irritation. It rarely causes hypoglycemia, if it is used as a single antidiabetic drug. Nevertheless, an overdose of metformin can cause lactic acidosis. Thus, metformin is contraindicated in diabetic patients with kidney diseases and other conditions that might increase the risk of lactic acidosis. Similar to other drugs, allergy to metformin may occur. Metformin allergy is extremely rare. Leukocytoclastic vasculitis and psoriasiform drug eruption are the two most common presentations of metformin allergy.[7–9] In quoted reports,[7–9] the patients usually develop a rash within a few days of metformin administration and the skin lesions disappear after stopping the drug. In addition, resolution of skin manifestations in metformin allergy, within several days after withdrawal of the drug, and their recurrence when the drug is reintroduced is also seen. As the patient had refused biopsy and other tests, this case was diagnosed as a probable case of metformin allergy. Based on the Naranjo probability assessment scale, the adverse effects were probably due to metformin. The clinical presentation of metformin allergy can occur in several forms. The mucocutaneous manifestation is the most common. In addition to leukocytoclastic vasculitis and psoriatic drug eruption, lichenoid reaction of the oral mucosa may also occur. Lamey et al. have proposed that the Grinspan's syndrome (the triad of oral lichen planus, diabetes mellitus, and hypertension) could be seen in Continue reading >>
Ability To Take Metformin In A Patient With Stevens-johnson Syndrome Associated With The Administration Of Bactrim
Ability to take metformin in a patient with Stevens-Johnson syndrome associated with the administration of Bactrim We have a patient who had Stevens-Johnson Syndrome from Bactrim. Can this patient safely take Metformin? Was recommended from his Internist to stop Metformin and see an allergist for further recommendations. Only information we could find was from the Drug Guide under Precautions and Warnings with Metformin that states "if you are allergic to sulfa medications, you may also be allergic to metformin-though most people with sulfa allergies can take Metformin without problems." We have had many questions submitted to our website regarding the potential cross-reactivity between sulfonamide antibiotics and other drugs which may contain sulfa. For the most part, there is no documented cross-reactivity between these drugs, and although there are warnings against taking metformin if you have reacted to a sulfonamide, I could not find any cases of such cross-reactivity. I believe that the answer to your question is identical to that in our previous response to a similar question below. "Cross-reactivity between sulfonylureas and drugs containing the sulfa moiety What recommendation would you make to a patient who has had agranulocytosis attributed to sulfasalazine, with regard to future use of other sulfa-containing drugs such as thiazide diuretics, Celecoxib, or sulfonamide antibiotics? My attempt to search the literature did not yield an answer... I could not glean whether these agranulocytosis reactions are usually specific to the individual drug or whether there may be cross-reactivity among chemically-related compounds in this context. I would appreciate any insight you may have. Thank you. I am afraid the reason that you have not been able to find any definit Continue reading >>
Important Information About The Side Effects Of
JANUMET What is the most important information I should know about JANUMET? Serious side effects can happen in people taking JANUMET, including: 1. Lactic Acidosis. Metformin, one of the medicines in JANUMET, can cause a rare but serious condition called lactic acidosis (a buildup of an acid in the blood) that can cause death. Lactic acidosis is a medical emergency and must be treated in the hospital. Call your doctor right away if you have any of the following symptoms, which could be signs of lactic acidosis: you feel cold in your hands or feet you feel dizzy or lightheaded you have a slow or irregular heartbeat you feel very weak or tired you have unusual (not normal) muscle pain you have trouble breathing you feel sleepy or drowsy you have stomach pains, nausea or vomiting Most people who have had lactic acidosis with metformin have other things that, combined with the metformin, led to the lactic acidosis. Tell your doctor if you have any of the following, because you have a higher chance for getting lactic acidosis with JANUMET if you: have severe kidney problems or your kidneys are affected by certain x-ray tests that use injectable dye have liver problems drink alcohol very often, or drink a lot of alcohol in short-term "binge" drinking get dehydrated (lose a large amount of body fluids). This can happen if you are sick with a fever, vomiting, or diarrhea. Dehydration can also happen when you sweat a lot with activity or exercise and do not drink enough fluids have surgery have a heart attack, severe infection, or stroke The best way to keep from having a problem with lactic acidosis from metformin is to tell your doctor if you have any of the problems in the list above. Your doctor may decide to stop your JANUMET for a while if you have any of these things. 2. Continue reading >>
What Are The Possible Side Effects Of Glipizide And Metformin (metaglip)?
A A A Medications and Drugs Brand Names: Metaglip Generic Name: glipizide and metformin (Pronunciation: GLIP ih zyd and met FOR min) What is glipizide and metformin (Metaglip)? Glipizide and metformin is a combination of two oral diabetes medicines that help control blood sugar levels. Glipizide and metformin is for people with type 2 diabetes who do not use daily insulin injections. This medication is not for treating type 1 diabetes. Glipizide and metformin may also be used for purposes not listed in this medication guide. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. This medication may cause lactic acidosis (a build-up of lactic acid in the body, which can be fatal). Lactic acidosis can start slowly and get worse over time. Get emergency medical help if you have even mild symptoms of lactic acidosis, such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, slow or uneven heart rate, dizziness, or feeling very weak or tired. Stop taking this medication and call your doctor at once if you have a serious side effect such as: feeling short of breath, even with mild exertion, swelling or rapid weight gain; pain or burning with urination; nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure). Less serious side effects may include: cold symptoms such as stuffy nose, sneezing, sore throat; headache, dizziness; mild nausea, vomiting, diarrhea, st Continue reading >>
Uses Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb. How to use Metformin HCL Read the Patient Information Leaflet if available from your pharmacist before you start taking metformin and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Take this medication by mouth as directed by your doctor, usually 1-3 times a day with meals. Drink plenty of fluids while taking this medication unless otherwise directed by your doctor. The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). To reduce your risk of side effects (such as upset stomach), your doctor may direct you to start this medication at a low dose and gradually increase your dose. Follow your doctor's instructions carefully. Take this medication regularly in order to get the most benefit from it. Remember to use it at the same times each day. If you are already taking another diabetes drug (such as chlorpropamide), follow your doctor's directions carefully for stopping/continuing the old drug and starting metformin. Check your blood sugar regularly a Continue reading >>
NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. What is in this leaflet This leaflet answers some common questions about Glucophage. It does not contain all the available information. It does not take the place of talking to your doctor, diabetes educator or pharmacist. All medicines have benefits and risks. Your doctor has weighed the risks of you taking Glucophage against the benefits expected for you. If you have any concerns about taking this medicine, talk to your doctor, pharmacist or diabetes educator. What Glucophage is used for Glucophage is used to control blood glucose (the amount of sugar in the blood) in people with diabetes mellitus. type 1 diabetes, also called insulin dependent diabetes or juvenile onset diabetes, when insulin alone is not enough to control blood glucose levels type 2 diabetes, also called non-insulin dependent diabetes mellitus (NIDDM) or maturity onset diabetes. It is especially useful in those who are overweight, when diet and exercise are not enough to lower high blood glucose levels (hyperglycaemia) Glucophage can be used alone, or in combination with other medicines for treating diabetes. Ask your doctor if you have any questions about why Glucophage has been prescribed for you. Glucophage is not recommended for use in children, except for those with insulin-resistant diabetes who are being treated in hospital. Glucophage is available only with a doctor's prescription. How Glucophage works Glucophage belongs to a group of medicines called biguanides. Glucophage lowers high blood glucose (hyperglycaemia) by helping your body make better use of the insulin produced by your pancreas. People with type 2 diabetes are unable to make enough insulin or their body does not respond properly to th Continue reading >>
Exercises Allergic Reaction To Metformin
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In The Past I've Had Allergic Reactions To Metformin And My Current Dr. Had Me Placed On It Again. Should I Be Taking This?
Hello VMKmaggie, This situation can be very serious. No one should take a medication which they believe they are allergic. Each time body is challenged by the “allergy causing compound”, the stronger the allergic reaction will be. Any questions about being allergic to any medication allergy should be addressed in any and all ways until resolved, meaning that you, the patient, is comfortable in taking the medication. • Never ever take a medication that you feel many have caused you to have an allergic reaction until your questions are resolved. • Prescriber offices (doctors and nurses) are changing over to the electronic record. Allergy information or other information may have been omitted or entered incorrectly. • Ask the office to check your old (hard copy) records. If you know the date that the medication caused the “allergy”, please provide the dates with staff as this will help them in looking through your record. • Another thing that may have happened, is that patients sometimes report how they respond to a medication and call it an allergy, the prescribers doesn’t classify the response as an allergy but as a reaction to the medication and your response may have not have flagged as an “allergy”. • Always clearly describe your response to any medication. • The allergy alert should have also been in the dispensing pharmacy’s computer system. Any allergies and/or reactions to medications should be shared with all the pharmacies/pharmacist s that provides services to you. Pharmacists can many times more rapidly follow up with the prescriber and are an advocate for patients. • Always consult a second opinion if you continue to feel the situation unresolved. • Always keep an updated list of medications, allergies and medication procedures Continue reading >>
Insulin And Other Allergic Reactions Does Diabetes Make A Difference?
There are various types of allergic reactions that we will examine, some of which can have a very profound effect on blood glucose control. The one that can be considered to be part of the normal pathogenesis of diabetes, although not common due to the uses of human DNA insulin, is an allergy to injected insulin.[i] These occurrences have been declining as beef and pork insulins are being replaced.[ii] [iii] Nevertheless this can be a serious problem to those that develop this allergy. Difficulties in blood sugar control and increasing insulin dosages, which progress far more rapidly than the normal pathology of the disease, may be the first symptoms. This may also be accompanied by local injection site irritation with the development of wheals.[iv] Even with some or all of these symptoms present, this condition may still be dismissed by doctors as an expected part of the disease process. While all these suspicions can easily be verified by blood testing for an increase in anti-insulin antibodies, it may take several detours before you arrive at that point. Some of the clues that will lead to this conclusion might be revealed in more common blood testing. A typical complete blood count (CBC) would likely show a definite increase in eosinophil cells, which could denote an allergic response. This result would probably be followed by another blood test for immunoglobulin E (IgE). There are five basic classes of immunoglobulins (IgA, IgD, IgE, IgG and IgM), and a number of different subclasses. They function as specific systemic antibodies in the blood and other body fluids. An elevated IgE value would be a very significant, but not necessarily an inclusive indication of an allergic condition even though it can coincide with an insulin allergy.[v] [vi] Nevertheless, a high Continue reading >>
What Are The Possible Side Effects Of Glyburide And Metformin (glucovance)?
A A A Medications and Drugs Brand Names: Glucovance Generic Name: glyburide and metformin (Pronunciation: GLYE bure ide and met FOR min) What is the most important information I should know about glyburide and metformin (Glucovance)? What is glyburide and metformin (Glucovance)? Glyburide and metformin is a combination of two oral diabetes medicines that help control blood sugar levels. Glyburide and metformin is used to treat type 2 diabetes. This medication is not for treating type 1 diabetes. Glyburide and metformin may also be used for purposes not listed in this medication guide. This medication may cause lactic acidosis (a build-up of lactic acid in the body, which can be fatal). Lactic acidosis can start slowly and get worse over time. Get emergency medical help if you have even mild symptoms of lactic acidosis, such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, slow or uneven heart rate, dizziness, or feeling very weak or tired. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using this medicine and call your doctor at once if you have a serious side effect such as: pale or yellowed skin, dark colored urine, fever, confusion or weakness; or nausea, upper stomach pain, itching, loss of appetite, clay-colored stools, jaundice (yellowing of the skin or eyes). Less serious side effects may include: sneezing, runny nose, cough or other signs of a cold; headache, mild dizziness; or mild dizziness; or mild nausea or vomiting, diarrhea, upset stomach. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You Continue reading >>
Metformin Causing Hives | Diabetic Connect
I take Met 500 mg once a day and am type 2. The only time I get hives is when I eat something and have an allergic reaction. According to Bristol Myers Squib, metformin does not cause hives. I read this on their site when I first started taking it. It could be something you ate. Call your doctor, if hives are severe they can cause death. I learned this when I developed an allergy to nuts. I was having lunch with a classmate when I was taking EMT classes. Our instructor who is a Nationally Registered Paramedic joined us and bought us each a chocolate chip cookie with nuts. My lips started tingling but I paid no attention to it. My classmate noticed hives breaking out on my face. Our instructor sent her to his car to get his medical kit. By the time she returned, my throat was beginning to close. He was able to give me a shot of epinephrine which stopped my throat from closing. I immediately called my doctor and had a series of allergy testing done. I think this may be what you need to do. You can actually develop an allergy to foods you are accustomed to eating at any age. Good luck to you. Did the hives start when you started taking the Met? I would talk to your doctor ASAP in any case-hives being not so much fun Continue reading >>
Metformin (oral Route)
Description and Brand Names Drug information provided by: Micromedex US Brand Name Fortamet Glucophage Glucophage XR Glumetza Riomet Descriptions Metformin is used to treat high blood sugar levels that are caused by a type of diabetes mellitus or sugar diabetes called type 2 diabetes. With this type of diabetes, insulin produced by the pancreas is not able to get sugar into the cells of the body where it can work properly. Using metformin alone, with a type of oral antidiabetic medicine called a sulfonylurea, or with insulin, will help to lower blood sugar when it is too high and help restore the way you use food to make energy. Many people can control type 2 diabetes with diet and exercise. Following a specially planned diet and exercise will always be important when you have diabetes, even when you are taking medicines. To work properly, the amount of metformin you take must be balanced against the amount and type of food you eat and the amount of exercise you do. If you change your diet or exercise, you will want to test your blood sugar to find out if it is too low. Your doctor will teach you what to do if this happens. Metformin does not help patients does not help patients who have insulin-dependent or type 1 diabetes because they cannot produce insulin from their pancreas gland. Their blood glucose is best controlled by insulin injections. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Tablet Tablet, Extended Release Solution Before Using In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies Tell your doctor if you have ev Continue reading >>
Metformin, Oral Tablet
Metformin oral tablet is available as both a generic and brand-name drug. Brand names: Glucophage, Glucophage XR, Fortamet, and Glumetza. Metformin is also available as an oral solution but only in the brand-name drug Riomet. Metformin is used to treat high blood sugar levels caused by type 2 diabetes. FDA warning: Lactic acidosis warning This drug has a Black Box Warning. This is the most serious warning from the Food and Drug Administration (FDA). A black box warning alerts doctors and patients to potentially dangerous effects. Lactic acidosis is a rare but serious side effect of this drug. In this condition, lactic acid builds up in your blood. This is a medical emergency that requires treatment in the hospital. Lactic acidosis is fatal in about half of people who develop it. You should stop taking this drug and call your doctor right away or go to the emergency room if you have signs of lactic acidosis. Symptoms include tiredness, weakness, unusual muscle pain, trouble breathing, unusual sleepiness, stomach pains, nausea (or vomiting), dizziness (or lightheadedness), and slow or irregular heart rate. Alcohol use warning: You shouldn’t drink alcohol while taking this drug. Alcohol can affect your blood sugar levels unpredictably and increase your risk of lactic acidosis. Kidney problems warning: If you have moderate to severe kidney problems, you have a higher risk of lactic acidosis. You shouldn’t take this drug. Liver problems warning: Liver disease is a risk factor for lactic acidosis. You shouldn’t take this drug if you have liver problems. Metformin oral tablet is a prescription drug that’s available as the brand name drugs Glucophage, Glucophage XR, Fortamet, and Glumetza. Glucophage is an immediate-release tablet. All of the other brands are extended-r Continue reading >>
Studies Allergic Reaction To Metformin
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