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Serum Glucose 101

1-hour Glucose Challenge Test Or Gct (plasma, Serum) During Pregnancy

1-hour Glucose Challenge Test Or Gct (plasma, Serum) During Pregnancy

What is the 1-Hour Glucose Challenge Test GCT? The 1-hour glucose challenge test or GCT measures the effect of a glucose solution on blood glucose levels. Patients are brought into the lab where one blood sample is taken 1-hour after a glucose solution is consumed. The glucose solution typically contains 50 grams of glucose but may also contain 75 or 100 grams. The 1-hour glucose challenge test is a screening test done to identify who may be at risk of diabetes. It does not usually diagnose diabetes but done to identify those who require additional testing. Pregnant women take the 1-hour glucose tolerance test as a screening tool for gestational diabetes. If the test results are below 130 mg/dl (or below 140 mg/dl) then no additional testing is required. If the test is above 130 mg (135 or 140 mg) then a 3-hour glucose tolerance test or GTT is ordered. The 3-hour glucose tolerance test uses a 100 gram glucose solution. If non-fasting glucose levels are greater than 126 mg/dL or normal daily glucose levels are greater than 200 mg/dL, glucose tolerance testing is not necessary as these measurements indicate diabetes. Normal Value Range Adult Non-Pregnant and Pregnant: Below 130 to 140 mg/dL or 7.2 to 7.8 mmol/L < Laboratory Values During Pregnancy Continue reading >>

Normal Non-fasting Glucose Levels - Medhelp

Normal Non-fasting Glucose Levels - Medhelp

By subscribing, you agree to the Terms of Use and Privacy Policy Common Questions and Answers about Normal non-fasting glucose levels Every site seems to have different ranges for what is normal and abnormal with fasting or non - fasting levels . I am somewhat confused, last night before bedtime 5.5 hrs after my meal, I had one cup of soda or Dr. Pepper. Do you think that is pre diabetes or Diabetes type 2 if it was at 154 mg/dl or does it not count? I was also diagnosed pre diabetic of 108 mg/dl, fasting all day 3 weeks back. This morning before breakfast it was 70 mg/dl. Is that normal? Both of your values suggest that you have impaired fasting glucose (range 100 - 125). The measurement is the same in fasting and non fasting testing - the difference is in the reference range. A normal fasting glucose is < 100 and the current thinking seems to be that even a result in the mid to high 90s might suggest close monitoring. The answer to your question is that it doesn't matter whether they call it non fasting or fasting glucose test result. I had my glucose test this morning. My instructions were to eat a normal breakfast but to avoid sugars and juice. Since I was at the labs at 7:00 am this morning I elected to not eat before and had breakfast after the test. The lab technician did not ask if I had fasted. The test I took was the one where you have a small drink- you must drink it in 5 minutes or less, and an hour from that they draw your blood. The first one. Hopefully everything is good. triglycerides - at normal levels too. High lipids and high glucose go hand-in-hand.Holly basil? Used in Thai cooking. Not proven to help with diabetes nor proven to lower blood glucose levels. There's lots of snake oil on the internet touting this and that cure but all unproven. Don't b Continue reading >>

Glucose Test

Glucose Test

Testing blood sugar levels A glucose test is a type of blood test used to determine the amount of glucose in the blood. It is mainly used in screening for prediabetes or diabetes.[1] Patients are instructed not to consume anything but water during the fasting period. Caffeine will also distort the results. If the person eats during the period in which he or she is supposed to have been fasting then they may show blood sugar levels that may cause his or her doctor to think the person has or is at increased risk of having diabetes. In people already having diabetes, blood glucose monitoring is used with frequent intervals in the management of the condition.[1] There are several different kinds of glucose tests: Fasting blood sugar (FBS), fasting plasma glucose (FPG): 8 or 12 or 14 hours after eating Glucose tolerance test:[2] continuous testing Postprandial glucose test (PC): 2 hours after eating Random glucose test Reference ranges[edit] Fasting blood sugar[edit] A range of 4 to 5.5 mmol/l (70 to 99 mg/dl) before a meal is normal. Continual fasting levels of 5.5 to 7 mmol/l (101–125 mg/dl) causes concern of possible prediabetes and may be worth monitoring. 7 mmol/l (126 mg/dl) and above means a risk of diabetes.[3] After a 12‑hour fast, a range of 3.9 to under 5.5 mmol/l (70.2 to 100 mg/dl) is normal; a level of 5.6 to under 7 mmol/l (100 to 126 mg/dl) is considered a sign of prediabetes.[3] Postprandial glucose[edit] Main article: Postprandial glucose test A level of < 7.8 mmol/l (140 mg/dl) 90 minutes after a meal is normal.[4] See also[edit] Glucose meter Hyperglycemia Hypoglycemia [edit] Continue reading >>

Fluoride & Impaired Glucose Tolerance

Fluoride & Impaired Glucose Tolerance

The proper regulation of blood glucose levels is essential to good health. When the body’s ability to regulate blood glucose levels falters, as occurs in diabetes mellitus, chronic elevated glucose levels (hyperglycemia) can lead to serious complications. These consequences include damage to the kidneys, nervous system, cardiovascular system, retina, legs and feet, etc. As documented by the research cited below, studies on both humans and animals have found that excessive fluoride intake produces an increase in the levels of glucose in blood. In 2006, the National Research Council summarized the available literature as follows: “The conclusion from the available studies is that sufficient fluoride exposure appears to bring about increases in blood glucose or impaired glucose tolerance in some individuals and to increase the severity of some types of diabetes. In general, impaired glucose metabolism appears to be associated with serum or plasma fluoride concentrations of about 0.1 mg/L or greater in both animals and humans (Rigalli et al. 1990, 1995; Trivedi et al. 1993; de al Sota et al. 1997). In addition, diabetic individuals will often have higher than normal water intake, and consequently, will have higher than normal fluoride intake for a given concentration of fluoride in drinking water. An estimated 16-20 million people in the United States have diabetes mellitus (Brownlee et al. 2002; Buse et al. 2002; American Diabetes Association 2004; Chapter 2); therefore, any role of fluoride exposure in the development of impaired glucose metabolism or diabetes is potentially significant.” (NRC 2006) Additional research has been published since the NRC’s review in 2006 that further confirms a relationship between fluoride exposure and elevated blood glucose. This r Continue reading >>

Glucose And The Injured Brain-monitored In The Neurointensive Care Unit

Glucose And The Injured Brain-monitored In The Neurointensive Care Unit

Importance of Glucose Monitoring in Neurointensive Care The development of neurointensive care (NIC) has had a huge impact on improving outcome and reducing mortality in patients with critical neurological conditions (1–4). This NIC includes mainly care for patients with traumatic brain injury (TBI), subarachnoid hemorrhage (SAH), intracranial hemorrhage, spinal cord injury, and acute ischemic stroke. The acute injured brain is characterized by a primary and a secondary injury. Primary brain injury is the acute insult to the brain that can be ischemia, hemorrhage, or trauma among others and is irreversible. The different types of primary injuries trigger secondary injury processes such as posttraumatic ischemia, energy failure, excitotoxicity, mitochondrial failure, oxidative stress and release of free radicals, secondary cerebral swelling, and inflammation (5, 6). Ischemia plays a major role in the pathology of injured brain and low cerebral glucose values are detected in ischemia. The injured brain might also be subjected to secondary clinical insults, e.g., high intracranial pressure, hypoxia, hyperglycemia, and hypoglycemia. Hyperglycemia is a common secondary insult in TBI, SAH, and acute ischemic stroke and has repeatedly been associated with poor neurological outcome. A great challenge for the treatment of patients with acute brain injury in the NIC unit is to detect early signs of secondary injuries in order to prevent further advancement and deterioration of the brain tissue. Microdialysis is a widely used technique to monitor the metabolic state of the injured brain and detect metabolic crises defined as low glucose and high lactate/pyruvate ratio (7–9). Monitoring of brain glucose has become even more important due to the increasing interest in controllin Continue reading >>

Blood Glucose Concentration And Risk Of Pancreatic Cancer: Systematic Review And Dose-response Meta-analysis

Blood Glucose Concentration And Risk Of Pancreatic Cancer: Systematic Review And Dose-response Meta-analysis

Abstract Objective To evaluate potential linear and non-linear dose-response relations between blood glucose and risk of pancreatic cancer. Design Systematic review and dose-response meta-analysis of prospective observational studies. Data sources Search of PubMed, Scopus, and related reviews before 30 November 2013 without language restriction. Eligibility criteria Prospective studies evaluating the association between blood glucose concentration and pancreatic cancer. Retrospective and cross sectional studies excluded to avoid reverse causality. Data extraction and synthesis Two reviewers independently extracted relevant information and assessed study quality with the Newcastle-Ottawa scale. Random effects dose-response meta-analysis was conducted to assess potential linear and non-linear dose-response relations. Results Nine studies were included for analysis, with a total of 2408 patients with pancreatic cancer. There was a strong linear dose-response association between fasting blood glucose concentration and the rate of pancreatic cancer across the range of prediabetes and diabetes. No non-linear association was detected. The pooled rate ratio of pancreatic cancer per 0.56 mmol/L (10 mg/dL) increase in fasting blood glucose was 1.14 (95% confidence interval 1.06 to 1.22; P<0.001) without significant heterogeneity. Sensitivity analysis excluding blood glucose categories in the range of diabetes showed similar results (pooled rate ratio per 0.56 mmol/L increase in fasting blood glucose was 1.15, 95% confidence interval 1.05 to 1.27; P=0.003), strengthening the association between prediabetes and pancreatic cancer. Conclusions Every 0.56 mmol/L increase in fasting blood glucose is associated with a 14% increase in the rate of pancreatic cancer. As prediabetes can be Continue reading >>

This Calculator Uses The 2007 Adag Formula To Estimate A1c And Average Blood Glucose Equivalents.

This Calculator Uses The 2007 Adag Formula To Estimate A1c And Average Blood Glucose Equivalents.

Enter a value into one of the fields below then press convert. A1c Value: Average Blood Glucose mg/dl or mmol/L Continue reading >>

The “normal Blood Sugar Range” May Be Misleading You

The “normal Blood Sugar Range” May Be Misleading You

A fasting blood sugar test measures the amount of a type of sugar, called glucose, in your blood after you have not eaten for at least eight hours. Checking for an ideal fasting blood sugar is one of the most commonly performed tests to check for prediabetes and type 2 diabetes. So what should your fasting blood sugar be? The normal blood sugar range is 65-99 mg/dL. If your fasting blood sugar is between 100 and 125 mg/dL, you have “impaired fasting glucose,” also referred to as “prediabetes.” If your fasting blood sugar is more than 126 mg/dL on two or more occasions, you have full-blown diabetes. What Is Prediabetes? People defined as having impaired fasting glucose/prediabetes are individuals whose blood sugar levels do not meet criteria for diabetes, yet are higher than those considered normal. These people are at relatively high risk for the future development of diabetes. According to the American Diabetes Association (ADA), prediabetes is not a disease itself but rather a risk factor “for diabetes as well as cardiovascular disease.”[1] However, the ADA also state that prediabetes can be considered an “intermediate stage” in the diabetes disease process.[1](One might wonder how prediabetes can be a both a risk factor for diabetes and an intermediate stage of the diabetes disease process simultaneously). In addition to increasing the chance of developing diabetes, it’s well-established that people with impaired fasting glucose/prediabetes are more likely to be overweight or obese, especially with what’s known as abdominal or visceral obesity. They also are more likely to have high triglycerides and/or low HDL cholesterol, and hypertension.[1] Even Normal-Range Blood Glucose Levels Can Increase Diabetes Risk There’s a lot more at stake for thos Continue reading >>

Diabetes 101: Why Your Blood Sugar Is A Big Deal

Diabetes 101: Why Your Blood Sugar Is A Big Deal

Diabetes is a disease that affects how your body uses sugar. If you have diabetes, no matter what type, it means you have too much sugar in your blood and this can lead to serious health problems. There are 3 types of diabetes. Prediabetes is when your blood sugar is high but not high enough to be diagnosed with diabetes. Type 1 diabetes, your body does not produce insulin at all and you need to give yourself insulin every day in order to live. Type 2 diabetes your body makes insulin but not enough to keep your blood sugar within normal limits. There are 3 tests used to diagnose diabetes and anyone over the age of 45 or with a body mass index greater than 25 should request one of these tests from their doctor. The 1st test is a fasting glucose which is exactly what it says, after having nothing to eat or drink for 8 hours; you get your blood sugar drawn. A normal fasting blood sugar level is less than 100. If it is between 100 and 125 then you are considered to have prediabetes. If it’s greater than 126, you’ll be diagnosed with diabetes. The 2nd test is a hemoglobin A1C. This blood test reflects the average of your blood sugar over 3 months. You do not have to be fasting for this test and it can be done at any time. A normal hemoglobin A1C level is less than 5.7 percent. Prediabetes is diagnosed if your hemoglobin A1C is 5.7 – 6.4 percent. If it is greater than 6.5 percent, then you have diabetes. The 3rd test is an oral glucose tolerance test. In this one, you have a fasting blood sugar drawn, then you drink a sugary drink and repeat your blood sugar in 2 hours. If your 2-hour blood sugar level is between 140 and 199 you have prediabetes. If your level is greater than 200 then you have diabetes. I know I threw a lot of numbers at you but do not worry. Here’s a Continue reading >>

Is Your Fasting Blood Glucose Higher On Low Carb Or Keto? Five Things To Know

Is Your Fasting Blood Glucose Higher On Low Carb Or Keto? Five Things To Know

This past spring, after 18 months of great success on the keto diet, I tested my fasting blood sugar on my home glucose monitor for the first time in many months. The result shocked me. I had purchased the device, which also tests ketones, when I was diagnosed with pre-diabetes in the fall of 2015. As I embarked on low-carb keto eating, I tested my blood regularly. Soon my fasting blood sugar was once again in the healthy range. I was in optimal ketosis day after day. Not only that, I lost 10 lbs (5 kg) and felt fantastic — full of energy with no hunger or cravings. Before long I could predict the meter’s results based on what I was eating or doing. I put the meter away and got on with my happy, healthy keto life. When my doctor ordered some lab tests this spring, I brought the meter out again. While I had no health complaints, excellent blood pressure and stable weight, she wanted to see how my cholesterol, lipids, HbA1c, and fasting glucose were doing on my keto diet — and I was curious, too. To check the accuracy of my meter against the lab results, on the morning of the test I sat in my car outside the clinic at 7:30 am, and pricked my finger. I was expecting to see a lovely fasting blood glucose (FBG) of 4.7 or 4.8 mmol/l (85 mg/dl). It was 5.8! (103 mg/dl). What? I bailed on the tests and drove home — I didn’t want my doctor warning me I was pre-diabetic again when I had no explanation for that higher result. The next morning I tested again: 5.9! (104). Huh??? For the next two weeks I tested every morning. No matter what I did, my FBG would be in 5.7 to 6.0 (102 to 106 mg/dl), the pre-diabetic range again. One morning after a restless sleep it was even 6.2 mmol/l (113 mg/dl). But my ketones were still reading an optimal 1.5-2.5 mmol/l. I was still burnin Continue reading >>

Atorvastatin Lowers Cholesterol But Raises Blood Sugar

Atorvastatin Lowers Cholesterol But Raises Blood Sugar

As many as 40 million people may be taking statin-type cholesterol-lowering drugs daily in the U.S. Although medications like atorvastatin, lovastatin, simvastatin, pravastatin, and rosuvastatin can bring cholesterol levels down dramatically they can also raise blood glucose levels or make diabetes harder to control as this reader relates: Q. I used to have good blood sugar readings when I was on glyburide. Since I was put on atorvastatin to lower cholesterol I have had trouble with high blood sugar. I read in your Guide to Managing Diabetes that statins can affect blood glucose but the clinical pharmacist at the VA said you are wrong. She insisted that atorvastatin does not affect HbA1c or blood sugar. They now have me on both glipizide and Onglyza and the clinical pharmacist admitted that my HbA1c will not come down. She still insists I have to keep taking these medicines even if they are not working to control my diabetes. A. We are puzzled that your pharmacist was not aware of the official prescribing information for atorvastatin (Lipitor): “Increases in HbA1c and fasting serum glucose levels have been reported with HMG-CoA reductase inhibitors [statins], including LIPITOR.” HbA1c is a measure of how high blood sugar levels have been over the past three months. Clinical trials and other studies have shown that statins can indeed raise blood sugar levels, making it harder to control diabetes. Blood Sugar and Statins: There is general agreement that statin therapy increases the risk of developing diabetes (Current Atherosclerosis Reports, Jan. 2015). Research has shown that there is a 10 to 12 percent increased incidence of new-onset type 2 diabetes in statin takers. The higher the dose and the more potent the statin the greater the risk. Investigators believe tha Continue reading >>

Understanding Fasting Blood Sugar

Understanding Fasting Blood Sugar

Among the most common questions people have about Type 2 diabetes is this: how can they lower their fasting blood sugar? To answer this question in a way that will help you lower your blood sugar we are going to have to first explain why doctors measure fasting blood sugar and what it does--and does not--tell us about our blood sugar health. WHAT IS FASTING BLOOD SUGAR? Traditionally, fasting blood sugar is the value you get when you test your blood sugar after an 8 hour long fast--which is usually immediately upon waking. In a normal person this fasting blood sugar would also be the "baseline" blood sugar--the level to which blood sugar returns a few hours after every meal all day long. However, for reasons we will discuss later on, this is often NOT the case for people with Type 2 diabetes, whose morning blood sugars may be much higher than the baseline level they achieve after meals for the rest of the day. Doctors have for decades relied on the FPG (fasting plasma glucose) test which measures fasting blood sugar to diagnose diabetes. The reason for this is NOT that FPG test results predict diabetic complications. They don't. Post-meal blood sugar tests are a much better indicator of whether a person will get the classic diabetic complications, and the A1c test is a better indicator of potential heart disease. But the FPG test is cheap and easy to administer, hence its popularity. The value most of us would find much more helpful in assessing our health is not fasting blood sugar but something else: the number of hours a day our blood sugar spends elevated over the level known to cause complications, which is roughly 140 mg/dl (7.7 mmol/L). A person can wake up with a FPG of 130 mg/dl (7.2 mmol/L), but if it drops after breakfast and most hours of the day are spent w Continue reading >>

Glucose Tolerance Test In Mice

Glucose Tolerance Test In Mice

Glucose tolerance test is a standard procedure that addresses how quickly exogenous glucose can be cleared from blood. Specifically, uptake of glucose from the blood by cells is regulated by insulin. Impairment of glucose tolerance (i.e, longer time to clear given amount of glucose) indicates problems with maintenance of glucose homeostasis (insulin resistance, carbohydrate metabolism, diabetes, etc). According to the WHO, in a standard oral glucose tolerance test (OGTT), glucose level should be below 7.8 mmol/L (140 mg/dl) at 2 h. Levels between this and 11.1 mmol/L (200 mg/dl) indicate “impaired glucose tolerance”, and any level above 11.1 mmol/L (200 mg/dl) confirms a diagnosis of diabetes. Materials and reagents Mice (~20 C57BL/6J (B6) males of 2-3 months old) 70% ethanol Beta-D(+)-glucose (Sigma-Aldrich, catalog number: G8270 ) NaCl KCl Sodium phosphate Phosphate buffered saline (PBS) (see Recipes) Equipment ACCU-CHEK comfort curve glucometer (Roche Diagnostics, catalog number: 03537536001 ) (this product has been discontinued. Any new product of ACCU-CHEK should work fine as well) Such device quantifies glucose amperometrically by measuring the current produced upon oxidation of glucose to gluconic acid by glucose oxidase, or to gluconolactone by dehydrogenase. 27 gauge needle (Single-Use Needles, supplied by VWR, BD Medical, catalog number: BD305109 ) Microvette CB300 Z serum separator (SARSTEDT, catalog number: 16.440.100 ) Acrodisc 25 mm syringe filters w/ 0.2 μM HT Tuffryn membrane (Pall Corporation, catalog number: 4192 ) Procedure Note: All the following experimental procedures that involve animals (rodents) should receive approval from IACUC or equivalent committee. Humane treatment of animals should be practiced all the time. In the Cavener lab, we us Continue reading >>

What Is Considered A High Level Of Serum Glucose?

What Is Considered A High Level Of Serum Glucose?

Glucose is required by the body to maintain life. However, it is possible to have too much of a good thing. Hyperglycemia, or high blood glucose levels, may be due to diabetes, medications, stress, illness, hyperthyroidism, Cushing syndrome, pancreatitis or pancreatitis cancer. It is important to know the symptoms of high blood glucose and to see your doctor immediately if you experience any signs to prevent further complications. Video of the Day A fasting blood glucose test is usually the first step to determining if you have high blood glucose levels, according to the National Institute of Diabetes and Digestive and Kidney Diseases. It is most reliable when done in the morning, after you have fasted for at least eight hours. Normal levels should be below 99 mg/dL. Pre-diabetes is diagnosed when levels are between 100 to 125 mg/dL. Diabetes is confirmed if your fasting blood glucose levels are 126 mg/dL or above on repeated tests. Random or nonfasting blood glucose levels of above 200 mg/dL could mean you have diabetes, as well. According to the American Diabetes Association, symptoms of high glucose levels include frequent urination, extreme hunger and thirst, extreme fatigue and irritability, unusual weight loss, frequent infections, blurred vision, tingling and numbness in the hands and feet, cuts and bruises that take a long time to heal, and recurring bladder, gum or skin infections. It is possible for you to have high glucose levels with no symptoms, so be sure to have your doctor check your levels at your regular physical. Dangers of Hyperglycemia The danger of continuously high blood glucose or hyperglycemia is that sugar coats the red blood cells, causing them to become stiff and “sticky”. These cells interfere with proper blood circulation and can cause Continue reading >>

Test Id: Glura Glucose, Random, Serum

Test Id: Glura Glucose, Random, Serum

Diagnosing and managing diabetes mellitus and other carbohydrate metabolism disorders including gestational diabetes, neonatal hypoglycemia, idiopathic hypoglycemia, and pancreatic islet cell carcinoma The most common disease related to carbohydrate metabolism is diabetes mellitus, which is characterized by insufficient blood levels of active insulin. Symptoms include polyuria, abnormally elevated blood and urine glucose values, excessive thirst, constant hunger, sudden weight loss, and possibly elevated blood and urine ketones. Complications from diabetes are the third leading cause of death in the United States. There are approximately 16 million diabetics in the United States, and that number is growing. It is estimated that at least 5 million of these people have not been diagnosed. The prevalence in the population age 65 and older is 18.4%, representing 6.3 million cases. The cost of diabetes to the US economy exceeds $92 billion annually. Overproduction or excess administration of insulin causes a decrease in blood glucose to levels below normal. In severe cases, the resulting extreme hypoglycemia is followed by muscular spasm and loss of consciousness, known as insulin shock. Any of the following results, confirmed on a subsequent day, can be considered diagnostic for diabetes: -Fasting plasma or serum glucose > or =126 mg/dL after an 8-hour fast -2-Hour plasma or serum glucose > or =200 mg/ dL during a 75-gram oral glucose tolerance test (OGTT) -Random glucose >200 mg/dL, plus typical symptoms Patients with "impaired" glucose regulation are those whose fasting serum or plasma glucose fall between 101 and 126 mg/dL, or whose 2-hour value on oral glucose tolerance test fall between 140 and 199 mg/dL. These patients have a markedly increased risk of developing type Continue reading >>

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