Can Too Much Metformin Cause High Blood Sugar

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NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. What is in this leaflet This leaflet answers some common questions about metformin It does not contain all the available information. It does not take the place of talking to your doctor or pharmacist or diabetes educator. The information in this leaflet was last updated on the date listed on the last page. More recent information on this medicine may be available. You can also download the most up to date leaflet from www.apotex.com.au. All medicines have risks and benefits. Your doctor has weighed the risks of you using this medicine against the benefits they expect it will have for you. Pharmaceutical companies cannot give you medical advice or an individual diagnosis. Keep this leaflet with your medicine. You may want to read it again. What this medicine is used for The name of your medicine is APO-Metformin 500, 850 or 1000 tablets. It contains the active ingredient metformin (as metformin hydrochloride). It is used to treat type 2 diabetes (also called non-insulin dependent diabetes mellitus or maturity onset diabetes) in adults and children over 10 years of age. It is especially use Continue reading >>

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  1. breakingreality

    I was put on Metformin to control my blood sugars about two weeks ago. 500mg pill twice a day. After logging my blood sugar levels for a week, the doctor told me to double the dosage. So now I am taking 1000mg twice a day and since doing that (for about 3 days) my blood sugars are still high, some even higher than they were before. Is there any reason that doubling the meds which are meant to lower your blood sugar would actually increase it, or would not have the same effect as a lower dosage?
    Most of my meals are between 30-60g of carbs (the dietitian recommended 45-60 but I cannot imagine the problem is not getting enough carbs). I've been exercising 3-5 days a week. My highest readings are usually right before bed, and first thing in the morning. Someone suggested my high blood sugar problem may be related to something other than insulin production in my pancreas, but I don't know enough to say if that's bs or not. The last two blood tests I had, which were a year apart, my white blood cell count was high. The diabetes specialist didn't comment on it, so I wasn't sure if this was important or could have any effect on my high blood sugar levels.
    For any of you on Metformin, have you had any similar issues? Are you taking any other meds to help control things? I will talk with the doctor again in 4-5 days after I fax the new results over, but I'm frustrated with the results so far.

  2. Cora1003

    First of all, don't forget that it can take up to 6 weeks for the metformin to get up to full strength in your system. It won't raise your glucose, but it doesn't lower glucose like insulin either.
    As for the amount of carbs, a good rule of thumb is to "eat to your meter". My husband (who is type 2, I am type 1), has been doing that and has good results. He eats between 120 and 160 g of carb per day. I haven't seen anyone online who does well with the ada recommended amount of carbs. It is just too high for most people's systems to handle. So eat a certain amount of carb and test 2 hours after. If you are too high, either cut out that food, or cut back the portion. Foods to avoid are typically "white" like pasta, potato, bread, rice.
    I'm sure that with the exercise, met, and diet modifications your blood sugar will come down.

  3. breakingreality


    Originally Posted by Cora1003
    So eat a certain amount of carb and test 2 hours after. If you are too high, either cut out that food, or cut back the portion. Foods to avoid are typically "white" like pasta, potato, bread, rice. I haven't eaten any bread or rice and very little potato since being diagnosed. I had maybe 1/2 cup of rice noodles with dinner last night and that was the first time I'd had pasta in a couple months. I'm having a hard time gauging foods, because it seems that even when I have very low carb meals, I still get high sugar levels. Since getting on the meds, I've been trying to get at least 15carbs per meal, and make sure it doesn't go higher than 60. So my breakfast usually consists of turkey and a cup of blackberries or raspberries, and sometimes an apple with peanut butter (which nets about 30 carbs).
    My blood sugar levels 2-3 hours after breakfast are usually between 150 and 180. Late at night they tend to be around 200 and in the morning a little lower, between 170-190. After lunch/before dinner is when they are at their lowest, last week between 125-150, the last time was 163 though.
    If it takes several weeks for the medicine to be at peak performance, is there a reason they are doubling the dosage after a week of logging?

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