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What Is A Type 4 Diabetes?

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New Type 4 Diabetes Not Linked To Obesity

Original article written by Bradley J. Fikes for The San Diego Union Tribune on November 18, 2015. Click here to read the original article. A new type of diabetes that’s not associated with insulin deficiency or obesity has been discovered — in mice. In a study published Wednesday, researchers led by Salk Institute scientists found that in a mouse model of the disease regarded as predictive of human diabetes, some develop an unusual type that affects old, lean mice. This disease is caused by overactivity of a certain kind of immune system cell. The researchers call this new form Type 4 diabetes. The study was published in the journal Nature. Go to j.mp/type4diabetes for the study. If the study is confirmed in people — a big if — the public health implications would be profound. Diabetes can lead to blindness, kidney and heart disease, and poor blood circulation that can lead to amputation. Diabetes is usually associated with obesity, and a form that is not may escape detection because doctors aren’t looking for it. The study was led by the Salk’s Ronald Evans and Ye Zheng. Evans said it’s possible that millions of Americans have this type of diabetes. “Oftentimes pe Continue reading >>

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Popular Questions

  1. Shravan Kumar

    Greetings!
    As a reminder, type 1 diabetes is the insulin-dependent form of diabetes mellitus where pancreatic beta cells (typically destroyed by an autoimmune response) do not supply insulin to the body to signal cellular glucose uptake, resulting in high blood sugar.
    Type 2 diabetes mellitus is primarily caused by insulin resistance (cells becoming desensitized to insulin’s action due to overuse), and decreased insulin production over time as the pancreas gets “worn out” from overproduction. This type of diabetes is often associated with obesity, inactivity, and aging.
    type 4 diabetes is associated with older age, rather than weight gain.

    You can join online communities like the diabetes community on the CareSpace app CareSpace - Android Apps on Google Play to meet others who suffer from it as well as doctors and physicians who can advice you further.

  2. Michael George

    It is not generally accepted nomenclature. Salk labs recently named type 4 diabetes insulin resistance coming with age in lean body types. Another obscure lab decided to call something else Type 4, unrelated to Salk’s findings I believe. My guess is that neither will stick — but I could be wrong.

  3. Ron Hunter

    One sign that you’re getting insulin resistant is that you start to gain weight. It’s somewhat a function of insulin triggering fat storage.

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