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Metabolic Effects Of Insulin

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The Science Of Insulin

Insulin is perhaps the most well known of all hormones and in the halls of health, fitness, and fat loss. It is mostly maligned and drastically misunderstood. As with many things in health and fitness there is more to the simple story told about insulin. Insulin basics Insulin functions very much like your hands when you are eating. Just as it would be extremely difficult to eat without hands, insulin feeds the tissue of the body in the same way. Insulin is required to facilitate nutrient uptake in the cells. Without insulin, your cells would literally starve and die. Insulin is made in the beta cells of the pancreas and is released into the blood stream in response to food. It assures these nutrients get into the cell. Insulin’s primary job is to make sure the cells have enough glucose, and therefore it has a strong impact on blood sugar levels. In fact, glucose is the primary stimulator of insulin release. In response to food and/or stress, blood glucose levels will rise. Insulin is used to lower blood sugar and balance things back out. Insulin Resistance Insulin works by increasing the amount of glucose receptors on the membranes of cells. So, when insulin interacts with cellu Continue reading >>

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Popular Questions

  1. Jennifer72

    Fasting Insulin Level after 12-20 Hour Fast

    Had a fasting insulin blood test done at lab yesterday morning at 8:30 AM. It's the first time I've done it. Was curious. Only cost me like $26 to find out. I already knew I was highly insulin resistant type 2. i.e. I know that 1 unit of regular insulin only covers 2 mg/dL of blood glucose (as a corrective dose).
    I hadn't eaten any solid food before blood test, except for 20 hours earlier. I had coffee about 12 1/2 hours before test.. Nothing after the coffee.
    My Fasting Insulin was 12.9 uIU/ml and my fasting blood glucose was 124 mg/dL. (Normal fasting insulin range is 2.6 to 24.9 according to the blood test sheet).
    My calculated HOMA-IR score is then (12.9*124)/405 = 3.95. A score of 1.0 or less is normal from what I've read -- i.e. not insulin resistant.
    Anyways, since this is the first time I've done this test, I'd appreciate if anyone could chime in and tell me all they can about what I just found out with the test.
    Is there any way to determine how strong my pancreas is with this test? Or should I follow this fasting insulin test with another in a couple days where I drink like 100g of glucose 1 hour before the test? If the fasting insulin level is the same, then my pancreas is doing all it can do when fasting even right?

  2. Nicoletti

    I've never had any type of insulin test and it's never occurred to me to have one. My thought is with the way I eat my blood sugars are decent and that's all I care about.

  3. Jennifer72

    Originally Posted by Nicoletti
    I've never had any type of insulin test and it's never occurred to me to have one. My thought is with the way I eat my blood sugars are decent and that's all I care about. Well I've done everything I can with respect to eating and can't get blood sugar below 110-135 range all day. So I am concerned about it. I am thinking my pancreas might be weakened too much.. but again you've seen the amount of insulin it's putting out. 12.9 .. normal is down to 2.9 .. so I guess it still must be somewhat strong? I'm just highly resistant.

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