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Why Is Ketosis Hard On The Kidneys

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Can A Ketogenic Diet Repair Damaged Kidneys?

Doing some research for another subject we will be talking about on this blog very soon, I cam across a very interesting paper from 2011 titled, Reversal of Diabetic Nephropathy by a Ketogenic Diet. What the paper shows was a group of mice were given both Type 1 and Type 2 Diabetes, then half the mice were switched to a ketogenic diet for 8 weeks. After 8 weeks the mice were dissected to determine what happened and here are the results the paper showed. Diabetic nephropathy, as indicated by albumin/creatinine ratios as well as expression of stress-induced genes, was completely reversed by 2 months maintenance on a ketogenic diet. However, histological evidence of nephropathy was only partly reversed. What this means is that the blood markers for kidney disease were completely reversed but the actual kidneys themselves still showed evidence of the damaged caused by the poor diet, but there was still some improvement. I would assume that staying on the ketogenic diet for longer than 8 weeks would show further improvement but no actual evidence of this was presented in this paper. Although more research is definitely needed, especially to see just how advanced kidney damage can be unt Continue reading >>

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Popular Questions

  1. Jilly986

    Does anyone have issues with kidney function and still successfully follow the LCHF regime? Although I am not being treated as such!, i.e. dialysis, I've been told my kidneys do not work at full capacity and have deteriorated significantly over the last couple of years. I am a little worried about what I have read about ketosis affecting the kidneys. Is it just a case of drinking lots of water? Should I take the issue up with my gp or renal consultant?

  2. paul-1976

    I've followed a ketogenic diet for around 2 years or so and I too have CKD and take Ramipril daily,My eGFR level has improved slightly on this diet,all I would add is don't go mad with eating protein and concentrate more on getting your calorific needs from fats and veggies etc.

  3. Jilly986

    Thank you for this advice. I have only been on the LCHF diet for 2 days so far. Already my blood sugars have stabilised so that's a good start. So far my diet has consisted of eggs, bacon, burgers, broth, cheese, double cream, nuts and berries. I dont feel at all hungry most of the time. Of course its too early to tell if there is any weight loss.
    So far I have not had any negative feedback re this diet although I saw my dietician yesterday and she wouldn't endorse it

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