Why Is Bicarb Low In Dka

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Diabetic Ketoacidosis

Diabetes mellitus is the name given to a group of conditions whose common hallmark is a raised blood glucose concentration (hyperglycemia) due to an absolute or relative deficiency of the pancreatic hormone insulin. In the UK there are 1.4 million registered diabetic patients, approximately 3 % of the population. In addition, an estimated 1 million remain undiagnosed. It is a growing health problem: In 1998, the World Health Organization (WHO) predicted a doubling of the worldwide prevalence of diabetes from 150 million to 300 million by 2025. For a very tiny minority, diabetes is a secondary feature of primary endocrine disease such as acromegaly (growth hormone excess) or Cushing’s syndrome (excess corticosteroid), and for these patients successful treatment of the primary disease cures diabetes. Most diabetic patients, however, are classified as suffering either type 1 or type 2 diabetes. Type 1 diabetes Type 1 diabetes, which accounts for around 15 % of the total diabetic population, is an autoimmune disease of the pancreas in which the insulin-producing β-cells of the pancreas are selectively destroyed, resulting in an absolute insulin deficiency. The condition arises in ge Continue reading >>

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Popular Questions

  1. flowerlady

    Since in DKA we have acidosis why there is decrease in HCO3 bicarbonate
    and why there is hyperkalemia if there is osmotic diuresis?

  2. step_enhancer

    usually when there is acidosis H+ goes into the cell and K+ comes out of the cell resulting in the hyperkalemia but intracellular hypokalemia.
    H+/K+ pump is present on the surface of the cells.
    pts with diabetic ketoacidosis have intracellular hypokalemia ,so they r given glucose,insulin and K+ to normalize their intracellular K+ to prevent arrhythmias.

  3. tiger73jo

    In DKA there is gain of fixed acids (ketone bodies ) causes excess (H+) ,
    and since there should be an equilibrium in the reaction (CO2) <--> (H+)+(HCO3-) then the reaction should shift to the left forming more CO2 (which result in hyperventilation ) and less HCO3
    for the hyperkalemia part i totally agree with step enhancer.

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