Why Does Metformin Cause Lactic Acidosis?

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A Ci= Confidence Interval B Extended-release Metformin Was Clinically Similar To Immediate-release Metformin Based On The Pre-defined

Page 1 of 22 Metformin Hydrochloride Extended-Release Tablets 500 mg and 1000 mg Rx only DESCRIPTION Metformin hydrochloride extended-release tablets contain an oral antihyperglycemic drug used in the management of type 2 diabetes. Metformin hydrochloride (N, N- dimethylimidodicarbonimidic diamide hydrochloride) is a member of the biguanide class of oral antihyperglycemics and is not chemically or pharmacologically related to any other class of oral antihyperglycemic agents. The empirical formula of metformin hydrochloride is C4H11N5•HCl and its molecular weight is 165.63. Its structural formula is: Metformin hydrochloride is a white to off-white crystalline powder that is freely soluble in water and is practically insoluble in acetone, ether, and chloroform. The pKa of metformin is 12.4. The pH of a 1% aqueous solution of metformin hydrochloride is 6.68. Metformin hydrochloride extended-release tablets are designed for once-a-day oral administration and deliver 500 mg or 1000 mg of metformin hydrochloride. In addition to the active ingredient metformin hydrochloride, each tablet contains the following inactive ingredients: ammonio methacrylate copolymer type A, ammonio metha Continue reading >>

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Popular Questions

  1. FatJessica

    > Ketosis taste in mouth?

    I caught a glimpse of a thread somewhere mentioning a taste in the mouth that some people get when they are in ketosis....anyone know what I'm talking about?

  2. MorganMac

    Yep, it's rather common. Ketone bodies (such as acetone) are excreted from the body in the breath and urine. Many people get "keto breath" for awhile when they start a LC diet :)

  3. FatJessica

    What does it smell like?

  4. -> Continue reading
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