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Which Of The Following Is Classified As A Ketone Body

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Fenofibrate Induces Ketone Body Production In Melanoma And Glioblastoma Cells

1Department of Food Biotechnology, Faculty of Food Technology, University of Agriculture, Krakow, Poland 2Molecular and Metabolic Oncology Program, Department of Oncologic Sciences, Mitchell Cancer Institute, University of South Alabama, Mobile, AL, USA 3Department of Human Nutrition, Faculty of Food Technology, University of Agriculture, Krakow, Poland 4Neurological Cancer Research, Stanley S Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA, USA Ketone bodies [beta-hydroxybutyrate (bHB) and acetoacetate] are mainly produced in the liver during prolonged fasting or starvation. bHB is a very efficient energy substrate for sustaining ATP production in peripheral tissues; importantly, its consumption is preferred over glucose. However, the majority of malignant cells, particularly cancer cells of neuroectodermal origin such as glioblastoma, are not able to use ketone bodies as a source of energy. Here, we report a novel observation that fenofibrate, a synthetic peroxisome proliferator-activated receptor alpha (PPARa) agonist, induces bHB production in melanoma and glioblastoma cells, as well as in neurospheres composed of non-transformed cells. U Continue reading >>

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Popular Questions

  1. Aniala

    Which of the following is classified as a ketone body?
    a. Sorbitol
    b. Pyruvate
    c. Acetyl CoA
    d. Acetoacetate
    e. Oxaloacetate

  2. Phillip

    ANS: D

  3. Sam Bruno

    Thanks for the answer, I sent you a forum message for another one.

  4. -> Continue reading
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