diabetestalk.net

What Is Lactic Acidosis

Share on facebook

Lactate And Lactic Acidosis

The integrity and function of all cells depend on an adequate supply of oxygen. Severe acute illness is frequently associated with inadequate tissue perfusion and/or reduced amount of oxygen in blood (hypoxemia) leading to tissue hypoxia. If not reversed, tissue hypoxia can rapidly progress to multiorgan failure and death. For this reason a major imperative of critical care is to monitor tissue oxygenation so that timely intervention directed at restoring an adequate supply of oxygen can be implemented. Measurement of blood lactate concentration has traditionally been used to monitor tissue oxygenation, a utility based on the wisdom gleaned over 50 years ago that cells deprived of adequate oxygen produce excessive quantities of lactate. The real-time monitoring of blood lactate concentration necessary in a critical care setting was only made possible by the development of electrode-based lactate biosensors around a decade ago. These biosensors are now incorporated into modern blood gas analyzers and other point-of-care analytical instruments, allowing lactate measurement by non-laboratory staff on a drop (100 L) of blood within a minute or two. Whilst blood lactate concentration i Continue reading >>

Share on facebook

Popular Questions

  1. driven1

    OK.... I'm a keto newbie, on Day 9 of the 12 day start up. As and aside, I feel great and am loving the food choices.
    ANYWAY... I have a girl friend who is an RN (and a very good one), who has cautioned me that ketones are 'hard on the kidneys'.
    Now, I love my GF to death, and I know that she means only the best, but I have very little confidence in the conventional medical community. After all, this is an industry that makes it's money from people being sick...
    My research has turned up that ketones are NOT damaging to the kidneys. On the contrary, the kidney uses ketones as a preferred fuel source when they can get them. The heart and brain as well as other major organs prefer them too...
    Seems as though the confusion is with the fact that a lot of medical professionals consider the excessive protein while on a keto diet damaging to the kidneys. I have also found research that dispels this... showing that only individuals who already have compromised kidney functions MIGHT have a problem with excess protein in the diet.
    I'm looking for comments from those who are experienced with the keto lifestyle. What do you know??

  2. titebuoy

    excessive dietary protein causes your kidneys to work harder to remove excess nitrogen. however, the keto is a high fat diet, not a high protein diet so i wouldnt be worried about it unless your macros are out of wack. some people have trouble with foamy urine on the diet, but most people dont experience kidney trouble on keto.

  3. stew9812

    I'm new to this too.
    I think what they teach the doctors/nurses is whats best for the general public. (people that don't work out, and don't necessarily get enough water ect..) So they may not always have the best answers for people like us.
    I would say to just drink plenty of water, and you will be fine.
    Just my opinion here, but like you say there is plenty of people who have done this diet with no bad side effects, and there is plenty of research supporting this to be a healthy diet as well.
    just my .02

  4. -> Continue reading
read more close

Related Articles

  • Is Ketoacidosis The Same As Lactic Acidosis

    Lactic acidosis is a medical condition characterized by the buildup of lactate (especially L-lactate) in the body, which results in an excessively low pH in the bloodstream. It is a form of metabolic acidosis, in which excessive acid accumulates due to a problem with the body's metabolism of lactic acid. Lactic acidosis is typically the result of an underlying acute or chronic medical condition, medication, or poisoning. The symptoms are generall ...

    ketosis Jan 16, 2018
  • Can Dka Cause Lactic Acidosis?

    Lactic acidosis is a form of metabolic acidosis that begins in the kidneys. People with lactic acidosis have kidneys that are unable to remove excess acid from their body. If lactic acid builds up in the body more quickly than it can be removed, acidity levels in bodily fluids — such as blood — spike. This buildup of acid causes an imbalance in the body’s pH level, which should always be slightly alkaline instead of acidic. There are a few ...

    ketosis Jan 13, 2018
  • What Are The Signs Of Lactic Acidosis With Metformin?

    Actos (pioglitazone) is an oral Type 2 diabetes drug that lowers blood sugar by decreasing insulin resistance and reducing the amount of glucose made in the liver. This allows the body to better dispose of excess blood sugar. Typically, the dose starts at 15 or 30 mg and is taken once a day, but some people may require a stronger dose. Doctors can increase the strength of the medicine by 15 mg increments to a maximum of 45 mg daily. However, nume ...

    ketosis Mar 29, 2018
  • Difference Between Lactic Acidosis And Ketoacidosis

    What is DKA in Dogs and Cats? Diabetic Ketoacidosis (DKA) is a serious and life-threatening complication of diabetes mellitus that can occur in dogs and cats. DKA is characterized by hyperglycemia, ketonemia, +/- ketonuria, and metabolic acidosis. Ketone bodies are formed by lipolysis (breakdown) of fat and beta-oxidation when the metabolic demands of the cells are not met by the limited intracellular glucose concentrations. This provides alterna ...

    ketosis Feb 24, 2018
  • Lactic Acidosis In Diabetes Mellitus

    Hyperglycaemic crises are discussed together followed by a separate section on lactic acidosis. DIABETIC KETOACIDOSIS (DKA) AND HYPERGLYCAEMIC HYPEROSMOLAR STATE (HHS) Definitions DKA has no universally agreed definition. Alberti proposed the working definition of “severe uncontrolled diabetes requiring emergency treatment with insulin and intravenous fluids and with a blood ketone body concentration of >5 mmol/l”.1 Given the limited availabi ...

    diabetes Dec 26, 2017
  • Lactic Acidosis Diabetes Symptoms

    History The onset of acidosis may be rapid (ie, within minutes to hours) or progressive (ie, over a period of several days). Lactic acidosis frequently occurs during strenuous exercise in healthy people, bearing no consequence. However, development of lactic acidosis in disease states is ominous, often indicating a critical illness of recent onset. Therefore, a careful history should be obtained to evaluate the underlying pathophysiologic cause o ...

    diabetes Feb 24, 2018

Popular Articles

More in ketosis