diabetestalk.net

What Is Dka Protocol?

Share on facebook

Treatment Of Diabetic Ketoacidosis With Subcutaneous Insulin Aspart

Abstract OBJECTIVE—In this prospective, randomized, open trial, we compared the efficacy and safety of aspart insulin given subcutaneously at different time intervals to a standard low-dose intravenous (IV) infusion protocol of regular insulin in patients with uncomplicated diabetic ketoacidosis (DKA). RESEARCH DESIGN AND METHODS—A total of 45 consecutive patients admitted with DKA were randomly assigned to receive subcutaneous (SC) aspart insulin every hour (SC-1h, n = 15) or every 2 h (SC-2h, n = 15) or to receive IV infusion of regular insulin (n = 15). Response to medical therapy was evaluated by assessing the duration of treatment until resolution of hyperglycemia and ketoacidosis. Additional end points included total length of hospitalization, amount of insulin administration until resolution of hyperglycemia and ketoacidosis, and number of hypoglycemic events. RESULTS—Admission biochemical parameters in patients treated with SC-1h (glucose: 44 ± 21 mmol/l [means ± SD], bicarbonate: 7.1 ± 3 mmol/l, pH: 7.14 ± 0.09) were similar to those treated with SC-2h (glucose: 42 ± 21 mmol/l, bicarbonate: 7.6 ± 4 mmol/l, pH: 7.15 ± 0.12) and IV regular insulin (glucose: 40 Continue reading >>

Share on facebook

Popular Questions

  1. PunchyHorse

    Hi, I'm wondering what the effects of caffeine (from black coffee) does to the body's insulin response, and how it affects ketosis.

  2. Emmie618

    I know that it spurs metabolism, but I doubt that it spikes blood glucose because drinking black coffee is allowed before a fasting blood test. Since blood glucose is one of the items being tested, I doubt that caffeine would be permitted if it affected blood glucose.

  3. TILnothingAMA

    I wasn't allowed to drink coffee before having my blood tested because it affect the cortisol/adrenaline level.

  4. -> Continue reading
read more close

Related Articles

Popular Articles

More in ketosis