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What Does Metabolic Acidosis Mean?

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Acute Metabolic Acidosis: Characterization And Diagnosis Of The Disorder And The Plasma Potassium Response

Acute Metabolic Acidosis: Characterization and Diagnosis of the Disorder and the Plasma Potassium Response *From the Medizinische Universitaetsklinik Kantonsspital Bruderholz, Bruderholz, Switzerland; and †Institute of Physiology, Departement of Veterinary Medicine, University of Zurich, Switzerland; and ‡Genentech Inc., South San Francisco, California. Correspondence to Dr. Reto Krapf, Medizinische Universitaetsklinik, Kantonsspital Bruderholz, CH 4101 Bruderholz/Basel, Switzerland. Phone: 0041-61-436-21-81; E-mail: reto.krapf{at}ksbh.ch Received for publication December 30, 2003. Accepted for publication February 25, 2004. ABSTRACT. Despite the high incidence of acute metabolic acidosis, there are no reliable human data to enable physicians to accurately diagnose this disorder. In addition, there is uncertainty about the direction and magnitude of plasma potassium changes in acute metabolic acidosis. The systemic and renal acid-base, electrolyte, and endocrine response to acute acid loads (imposed by three timed NH4Cl infusions into the duodenum, 0.9 mmol of NH4Cl per kg of body weight over 30 min each) was characterized in six healthy male subjects in whom a metabolic stead Continue reading >>

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Popular Questions

  1. One of our CDI noted an elevated lactic acid and queried the physician for a diagnosis. The patient did not have Sepsis. Our physician advisor said not to do that because the next lactic acid was normal. She said we should also be looking for the underlying cause of the lactic acidosis and not querying for the diagnosis. A diagnosis of lactic acidosis will give us a CC. Other CDI's have said that if the elevated lactic acid was treated, monitored or evaluated we should be querying for the diagnosis. Does anyone have any direction on how this should be handled?
    Is lactic acidosis always inherent in other conditions and that's what we should focus on?
    What can we pick up the diagnosis by itself as a CC / when should we query to get to documented in the chart?
    Are there any other clinical parameters we should be looking at when evaluating whether we should query such as the anion gap?
    Is there a specific treatment for metabolic acidosis?
    Thank you,
    Christine Butka RN MSN
    CDI Lead
    CentraState Medical Center
    Freehold, NJ

  2. What a timely comment. Recently, our coding auditor suggested that we should always keep an eye out for the cc "acidosis". It seems to me that lactic acidosis could be inherent to the disease process of sepsis and therefore should not be captured. Any thoughts?
    Yvonne B RN CDI Salinas, CA.

  3. Hello all! I agree, I believe lactic acidosis is inherent to sepsis. It is one of the most important indicators that gives the clnician a clue that sepsis may be present. Our fluid administration policy was actually developed on the lactic acid result: the higher the number, the more fluid we bolused (in non-CHF patients, of course). In cases were Sepsis is determined not to be present, we will query the provider, providing they treated or monitored the acidosis in some manner
    Shiloh

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