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What Are Ketones

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Ketone Bodies

Ketone bodies Acetone Acetoacetic acid (R)-beta-Hydroxybutyric acid Ketone bodies are three water-soluble molecules (acetoacetate, beta-hydroxybutyrate, and their spontaneous breakdown product, acetone) that are produced by the liver from fatty acids[1] during periods of low food intake (fasting), carbohydrate restrictive diets, starvation, prolonged intense exercise,[2], alcoholism or in untreated (or inadequately treated) type 1 diabetes mellitus. These ketone bodies are readily picked up by the extra-hepatic tissues, and converted into acetyl-CoA which then enters the citric acid cycle and is oxidized in the mitochondria for energy.[3] In the brain, ketone bodies are also used to make acetyl-CoA into long-chain fatty acids. Ketone bodies are produced by the liver under the circumstances listed above (i.e. fasting, starving, low carbohydrate diets, prolonged exercise and untreated type 1 diabetes mellitus) as a result of intense gluconeogenesis, which is the production of glucose from non-carbohydrate sources (not including fatty acids).[1] They are therefore always released into the blood by the liver together with newly produced glucose, after the liver glycogen stores have bee Continue reading >>

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Popular Questions

  1. skysiris

    I know that every diabetic should know what ketones are since I see a lot of people talking about them in Facebook groups, but I have no idea what that means. Can someone please explain to me what ketones are and how they're caused? Thanks in advance.

  2. justinsemag

    In short, ketones are a by-product of the body breaking down fat to create energy

  3. nitya_sharma

    Ketones are the result of the body burning fat for energy or fuel. For a person with diabetes, ketones are often the result of prolonged high blood sugar and insulin deficiency.If you have diabetes, you need to be especially aware of the symptoms that having too many ketones in your body can cause. These include:
    a dry mouth, blood sugar levels greater than 240 milligrams per deciliter (mg/dL), strong thirst, frequent urination,
    If you don’t get treatment, the symptoms can progress to:
    confusion, extreme fatigue, flushed skin, a fruity breath odor, nausea, vomiting, stomach pain, trouble breathing.
    Managing the carbohydrate intake and insulin dosage is vital for managing diabetes. If they have vomiting and/or have a high blood sugar that is not coming down despite medication, should contact the doctor immediately.

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