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Uncompensated Respiratory Acidosis

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Respiratory Acidosis

Respiratory acidosis is a medical emergency in which decreased ventilation (hypoventilation) increases the concentration of carbon dioxide in the blood and decreases the blood's pH (a condition generally called acidosis). Carbon dioxide is produced continuously as the body's cells respire, and this CO2 will accumulate rapidly if the lungs do not adequately expel it through alveolar ventilation. Alveolar hypoventilation thus leads to an increased PaCO2 (a condition called hypercapnia). The increase in PaCO2 in turn decreases the HCO3−/PaCO2 ratio and decreases pH. Terminology[edit] Acidosis refers to disorders that lower cell/tissue pH to < 7.35. Acidemia refers to an arterial pH < 7.36.[1] Types of respiratory acidosis[edit] Respiratory acidosis can be acute or chronic. In acute respiratory acidosis, the PaCO2 is elevated above the upper limit of the reference range (over 6.3 kPa or 45 mm Hg) with an accompanying acidemia (pH <7.36). In chronic respiratory acidosis, the PaCO2 is elevated above the upper limit of the reference range, with a normal blood pH (7.35 to 7.45) or near-normal pH secondary to renal compensation and an elevated serum bicarbonate (HCO3− >30 mm Hg). Causes Continue reading >>

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Popular Questions

  1. cjd12000

    Dexamethasone for ketosis

    Any one ever is Dex for treatment. Got fresh cow not responding to dextrose. Know you can treat them that way just wondering how effective

  2. Markwright

    RE: Dexamethasone for ketosis

    put it this way: dex won't hurt and has a good chance of helping her.
    when they don't respond to dextrose..that's not ussually good, btw.

  3. Jay NE Ohio

    Re: Dexamethasone for ketosis

    My vet has prescribed Dexamethazone at 10cc added to the dextrose for a maximum of two days in a row. He claims it helps increase their appetite. But if overused, it will decrease their immune system. I tried it, but did not feel that it helped much. Drench with propylene gycol in addition to the IV dextrose seems to work best for me. The Merck Vet manual mentions a therapy using a slow release insulin in addition to the above for severe cases: http://www.merckvetmanual.com/mvm/index.jsp?cfile=htm/bc/80900.htm
    I suspect that there is something else working on your cow and that is why she is not responding to the dextrose. Since she is fresh, I suspect mastitis or metritis. Could also be fatty liver, subclinical milk fever, hardware, LDA, ect. Have you tried some calcium (IV or bolus) to see if she responds?

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