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Metabolic Acidosis: Pathophysiology, Diagnosis And Management. Pdf

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Hemodynamic Consequences Of Severe Lactic Acidosis In Shock States: From Bench To Bedside

Hemodynamic consequences of severe lactic acidosis in shock states: from bench to bedside Kimmoun et al.; licensee BioMed Central.2015 The Erratum to this article has been published in Critical Care 2017 21:40 Lactic acidosis is a very common biological issue for shock patients. Experimental data clearly demonstrate that metabolic acidosis, including lactic acidosis, participates in the reduction of cardiac contractility and in the vascular hyporesponsiveness to vasopressors through various mechanisms. However, the contributions of each mechanism responsible for these deleterious effects have not been fully determined and their respective consequences on organ failure are still poorly defined, particularly in humans. Despite some convincing experimental data, no clinical trial has established the level at which pH becomes deleterious for hemodynamics. Consequently, the essential treatment for lactic acidosis in shock patients is to correct the cause. It is unknown, however, whether symptomatic pH correction is beneficial in shock patients. The latest Surviving Sepsis Campaign guidelines recommend against the use of buffer therapy with pH 7.15 and issue no recommendation for pH lev Continue reading >>

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Popular Questions

  1. walkerwally1

    Interpreting the ReliOn Ketone Test Strips

    I have been low carb, less than 25g/day, for the last week and was sure I was in ketosis but thought I would check with the ReliOn test strips from Walmart. My result was 40mg/dl on their chart which they call moderate. Everything I have read lists ketones as mmol and it is said ketosis is from 0.5 to 5.0 mmol. I thing 40mg/dl converts to about 2.2 mmol but I am not sure. If someone understands this better than me I would like to know if I am doing the conversion right.
    I am currently reading a book about Low Carb Living:
    The Art and Science of Low Carbohydrate Living: An Expert Guide to Making the Life-Saving Benefits of Carbohydrate Restriction Sustainable and Enjoyable: Stephen D. Phinney, Jeff S. Volek: 9780983490708: Amazon.com: Books
    I think this is one of the best books I have found so far, not better than Dr. Bernstein's or Jenny Ruhl's, but a great compliment to the lchf WOE. It goes into great detail about the science of low carb and why it works and is more natural than our high carb diets. It is written to inform professionals and they invite you to give a copy to your Doctor. The link is to Amazon so you can get more info and see some of the reviews it has received. I have no connection to this book or authors other than being impressed.

  2. Steve3129

    Quote:

    Originally Posted by walkerwally1
    I have been low carb, less than 25g/day, for the last week and was sure I was in ketosis but thought I would check with the ReliOn test strips from Walmart. My result was 40mg/dl on their chart which they call moderate. Everything I have read lists ketones as mmol and it is said ketosis is from 0.5 to 5.0 mmol. I thing 40mg/dl converts to about 2.2 mmol but I am not sure. I use these strips as well, but the only thing they tell you is if you are spilling Ketones in the urine, excess Ketones at that. The color code really doesn't tell you more other than the darker the color, the more your kidneys are taking out of the blood.
    You have to get a special meter and strips to accurately measure blood Ketones, which is rather expensive and I'm not willing to buy. I'm satisfied to know that I'm producing Ketones by the excess production as indicated by the strip.

  3. MCS

    If your showing any color on the urine test strip your in ketosis.

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