Metabolic Acidosis Pathophysiology

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4.2 Respiratory Acidosis - Causes

Acid-Base Physiology The arterial pCO2 is normally maintained at a level of about 40 mmHg by a balance between production of CO2 by the body and its removal by alveolar ventilation. If the inspired gas contains no CO2 then this relationship can be expressed by: paCO2 is proportional to VCO2 / VA where: VCO2 is CO2 production by the body VA is Alveolar ventilation An increase in arterial pCO2 can occur by one of three possible mechanisms: Presence of excess CO2 in the inspired gas Decreased alveolar ventilation Increased production of CO2 by the body CO2 gas can be added to the inspired gas or it may be present because of rebreathing : Anaesthetists are familiar with both these mechanisms. In these situations, hypercapnia can be induced even in the presence of normal alveolar ventilation and normal carbon dioxide production by the body. An adult at rest produces about 200mls of CO2 per minute: this is excreted via the lungs and the arterial pCO2 remains constant. An increased production of CO2 would lead to a respiratory acidosis if ventilation remained constant. The system controlling arterial pCO2 is very efficient (ie rapid and effective) and any increase in pCO2 very promptly re Continue reading >>

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Popular Questions

  1. Milena

    The question of how soon ketosis starts during the dry fast is a very frequent one. Hence, I decided to start a thread to discuss my own experiments with pre-fast meals and how they might or might not effect ketosis.
    On June 12th, 2011 I started my weekly 36-hrs dry fast at 20:00. Prior to eat I had a dinner of all-you-can-eat sushi which mostly consisted of refined carbs (white rice) and protein (fish) with simple carbs being the dominant ingredient. The dinner ended at 18:00, after which I had a cup of coffee and a glass of water before commencing the fast.
    23 hour mark my ketons were at NEGATIVE
    25 hour mark my ketons were at between TRACE and SMALL
    34.5 hour mark my ketons were at between TRACE and SMALL
    36 hour mark my ketons were still between TRACE AND SMALL
    So the conclusion is that while we do go into ketosis at about 24 hours the conversion is a very slow process if the pre-fast meal is mainly refined carbs with some protein.
    My next fast will commence on Wed June 15th when I will have my pre-fast meal either low starch carbs (fruit and veggies) or all protein like fish and egg.

  2. Yuliya

    Yuliya replied the topic: Re: Dry Fast and Ketosis
    Milena, I am a little confused why you call rice 'simple carbs'. In fact rice is complex carbohydrate.
    Simple carbs are things like fruit, and also sugar.
    Complex carbohydrates are chains of three or more single sugar molecules linked together. Long chains of sugar molecules called starches serve as a storage form of energy in plants and when you eat those plants, your body breaks down the carbohydrates for your own energy needs. Even though complex carbohydrates are made from chains of sugars, they do not taste sweet. Complex carbohydrates are more difficult to digest than simple carbohydrates, because we need to break them down first.
    Simple carbohydrates are broken down quickly by the body to be used as energy.
    Simple carbohydrates come in 2 forms: refined sugars (extracted from fruits, grains, tubers, and sugar cane) and whole-food sugars (primarily sweet fruits). Both refined and whole-food simple sugars taste sweet to our tongue.
    May compassion to yourself and all beings guide you in your eating, fasting, and lifestyle choices.
    All my posts are based on my opinions and experiences only and are not intended to replace the advice of the licensed medical practitioner.

  3. Milena

    Milena replied the topic: Re: Dry Fast and Ketosis
    I actually meant to say "refined carbs" since it was white rice not brown. Will make that correction right now.
    May the Energy you free from digesting serves your Body and Spirit well!
    All my posts are based on my opinions and experiences only and are not intended to replace the advice of the licensed medical practitioner.

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