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Lactic Acidosis In Cirrhosis

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Hemodynamic Consequences Of Severe Lactic Acidosis In Shock States: From Bench To Bedside

Hemodynamic consequences of severe lactic acidosis in shock states: from bench to bedside Kimmoun et al.; licensee BioMed Central.2015 The Erratum to this article has been published in Critical Care 2017 21:40 Lactic acidosis is a very common biological issue for shock patients. Experimental data clearly demonstrate that metabolic acidosis, including lactic acidosis, participates in the reduction of cardiac contractility and in the vascular hyporesponsiveness to vasopressors through various mechanisms. However, the contributions of each mechanism responsible for these deleterious effects have not been fully determined and their respective consequences on organ failure are still poorly defined, particularly in humans. Despite some convincing experimental data, no clinical trial has established the level at which pH becomes deleterious for hemodynamics. Consequently, the essential treatment for lactic acidosis in shock patients is to correct the cause. It is unknown, however, whether symptomatic pH correction is beneficial in shock patients. The latest Surviving Sepsis Campaign guidelines recommend against the use of buffer therapy with pH 7.15 and issue no recommendation for pH lev Continue reading >>

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Popular Questions

  1. SnowPetal

    Per week weightloss that is.

  2. thepapillon

    I've done this a few times while trying to lose weight... and am doing it now. I would say the first week you lose a lot. (5-7 pounds or so) After the first week I found it reduces to more like 3-4 pounds. I think it also depends on your weight. If you have extra weight, it'll come off easier than someone trying to get those last few pounds off. Good luck!

  3. SnowPetal

    That's good to know, thanks.
    I am also doing a lower calorie ketogenic diet as well. I'm hoping I can lose a pound a day like the hcg diet. But I will see.

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