How Do Ketosis And Ketoacidosis Differ?
For one a probably 3 to 10 time higher levels of circulating ketones. Here’s what you need to know. Ketones are a natural part of human metabolism. Everybody has circulating levels of ketones in their bodies. When you don’t eat for 12 hours over night your levels of ketones start to rise. The key regulator of ketone production is the hormone insulin. When insulin levels are high, circulating ketones are low. As insulin drops, ketone production starts to rise. Why? Ketones are an alternate fuel for certain tissues in the body. The body starts to ramp up production of ketones in case it needs them to help fuel things like the brain. When concentrations rise about 1 milimolar, the brain starts to burn them as fuel. Ketone metabolism breaks down when insulin is missing in the body. In type 1 diabetics or type 2’s that have beta cell failure, ketone levels can rise to levels of 15 to 25 milimolar. This lack of insulin also causes the massive release of fatty acids which acidify the body and cause the ketones to become toxic by acidifying the ketones. Typically someone on a low carb diet who is in ketosis will have levels of 2 to 3 milimolar. It is very rare for someone with insuli Continue reading >>