What Is Good For Heavy Metal Detoxification? And Does Going Into Ketosis Help?
Let me start with mercury because in some ways it is the most difficult heavy metal to excrete efficiently. Mercury bonds efficiently to sulfur, much better than it bonds to oxygen. Lead bonds to oxygen better, and this defines a critical difference in detox between different heavy metals. The body can have a high mercury burden and be asymptomatic. Teenagers with idiopathic dilated cardiomyopathy suddenly drop dead; that's how we find out they have toxic mercury burdens in their heart muscles. In humans, mercury is detoxified by binding to glutathione (GSH), which binds to mercury (Hg) by its sulfur (S) atoms. Glutathione is abbreviated GSH to emphasize the sulfhydryl (SH) active group, which when it bonds to mercury becomes GS-Hg-SG (two bonds to the sulfur (S) of glutathione). The H of GSH is replaced with mercury. This bound form of mercury is our body's primary mercury-defense mechanism, for storage in the cells and for elimination through the liver into the bile. The latter is where the problem begins. When mercury enters the digestive tract in bile, it runs into microorganisms. Bacteria hate mercury in the glutathione-bound form. It gets into their systems very efficiently, Continue reading >>