Ketosis In Animals

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Not to be confused with Ketoacidosis. Ketosis is a metabolic state in which some of the body's energy supply comes from ketone bodies in the blood, in contrast to a state of glycolysis in which blood glucose provides energy. Ketosis is a result of metabolizing fat to provide energy. Ketosis is a nutritional process characterised by serum concentrations of ketone bodies over 0.5 mM, with low and stable levels of insulin and blood glucose.[1][2] It is almost always generalized with hyperketonemia, that is, an elevated level of ketone bodies in the blood throughout the body. Ketone bodies are formed by ketogenesis when liver glycogen stores are depleted (or from metabolising medium-chain triglycerides[3]). The main ketone bodies used for energy are acetoacetate and β-hydroxybutyrate,[4] and the levels of ketone bodies are regulated mainly by insulin and glucagon.[5] Most cells in the body can use both glucose and ketone bodies for fuel, and during ketosis, free fatty acids and glucose synthesis (gluconeogenesis) fuel the remainder. Longer-term ketosis may result from fasting or staying on a low-carbohydrate diet (ketogenic diet), and deliberately induced ketosis serves as a medical i Continue reading >>

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Popular Questions

  1. anbeav

    Most animals don't have a mechanism for ketosis. Ketosis is a mechanism to provide energy for the brain. Animal brains do not require as much energy as humans and thus the energy requirements can be fulfilled via gluconeogenesis.

  2. anbeav

    My cat is on a keto diet (raw food carnivore diet) but ketones are always negative. Here's one of many articles I've read it in http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194504/. I've also talked to my vet about this.
    Cats are not humans. Humans have mechanisms for ketosis why are you assuming all animals do and in response to the same stimuli? Anyone can, yes. Not any animal. That's a big difference.
    Ketosis is ketosis. Even on a protein and fat only diet my cat is not in ketosis. His walnut sized brain doesn't demand it. Cats do get ketostix when diabetic but not just from eating a natural cat diet. I don't like it misrepresented either which is why I don't discuss things when drunk :)

  3. anbeav

    If you switched the cats diet it wouldn't go into ketosis though. I'm speaking of nutritional ketosis not ketoacidosis. Other animals don't achieve nutritional ketosis but can achieve ketoacidosis, not the same thing.
    And what do you mean that humans should never be in ketosis for extended periods of time? Why?
    You're mixing terms-ketosis and ketoacidosis

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