Why Do Ketones Produce Dehydration?
I assume you are referring to the high ketones associated with people who have Type I diabetes. These individuals cannot process carbohydrates properly, so they metabolize fatty acids and produce ketones for energy as an alternative to using glucose or carbs for energy. The ketones can build to dangerously high levels if the process is uncontrolled, even resulting in death. The ketones do not cause dehydration. The dehydration is caused by high glucose levels in the blood due to diabetics not being able to metabolize it for energy. This effect then causes fats to be metabolized to ketones for energy, and at the same time the high glucose in the blood causes the dehydration. So, the ketones and dehydration both are the result of the lack of metabolism of glucose, but ketones do not cause the dehydration. Ketones have a carbon-oxygen double bond in them called a carbonyl group. These groups are very prone to something called keto-enol tautomerization, meaning that the ketone form of the compound easily shifts in the right conditions (with water around usually) to its enol (has an “ene” double bond in the carbon backbone and an “ol” alcohol group) form. When a ketone is in the Continue reading >>