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Ketone Bodies In Urine

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Ketone Bodies: A Review Of Physiology, Pathophysiology And Application Of Monitoring To Diabetes.

Abstract Ketone bodies are produced by the liver and used peripherally as an energy source when glucose is not readily available. The two main ketone bodies are acetoacetate (AcAc) and 3-beta-hydroxybutyrate (3HB), while acetone is the third, and least abundant, ketone body. Ketones are always present in the blood and their levels increase during fasting and prolonged exercise. They are also found in the blood of neonates and pregnant women. Diabetes is the most common pathological cause of elevated blood ketones. In diabetic ketoacidosis (DKA), high levels of ketones are produced in response to low insulin levels and high levels of counterregulatory hormones. In acute DKA, the ketone body ratio (3HB:AcAc) rises from normal (1:1) to as high as 10:1. In response to insulin therapy, 3HB levels commonly decrease long before AcAc levels. The frequently employed nitroprusside test only detects AcAc in blood and urine. This test is inconvenient, does not assess the best indicator of ketone body levels (3HB), provides only a semiquantitative assessment of ketone levels and is associated with false-positive results. Recently, inexpensive quantitative tests of 3HB levels have become availab Continue reading >>

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Popular Questions

  1. Sez

    I have bought them in the past from Boots etc, but got so sick of the questioning decided to try to find them elsewhere on the WWW! (I felt a second class citizen using them just to check weight loss.....)
    I just bought 2 packs of 50 genuine Ketositx, long date, on Ebay for just over a tenner. I know its a gamble that they are in fact ok, but the seller had 99.3% positive (or thereabouts) so I thought it worth the risk!
    Any thoughts? Good price or dodgy deal?

  2. LizDesigns

    I've bought them from e-Bay before and Superdrug. Both cost around about £5 each so it sounds like you paid about the right price.
    As long as they haven't been tampered with I can't see you having any problems with them.

  3. shinyhappyperson

    Sainsburys pharmacy bit - £5.15.

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