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Ketoacidosis Turbid Definition

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Stress Induced Hyperglycemia In A Term Baby Mimicking Diabetic Ketoacidosis With Stroke

Go to: Stress/sepsis induced transient hyperglycemia in the newborn may present with extremely high blood sugar values and may mimic neonatal diabetes mellitus. We present a case of neonatal septicemia with stress induced hyperglycemia mimicking neonatal diabetes mellitus. Extremely high blood sugar values upto 1529 mg/dl with metabolic acidosis were noted in a term good weight baby causing a diagnostic dilemma. It can be seen even in term babies, contrary to the belief that it occurs in preterm and small for gestation babies. Considering the prognostic implications it may cause it is important that hyperglycemia is promptly treated by insulin infusion. Keywords: Hyperglycemia, insulin therapy, neonatal diabetes, stress Go to: Stress induced hyperglycemia is a known complication of Neonatal sepsis, but sometimes it may become very difficult to distinguish it from neonatal diabetes mellitus. We present a case of neonatal septicemia with stress induced hyperglycemia mimicking neonatal diabetes mellitus. Extremely high blood sugar values with metabolic acidosis were noted in a term good weight baby caused a diagnostic dilemma. Go to: CASE REPORT The present case report is about a 3 kg Continue reading >>

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Popular Questions

  1. Johanna

    I have found various sources saying that ketones are acidic (pKa=20), and then relate it to the formation of the enolate ion. However, isn't an enolate ion of a ketone basic due to the oxygen's negative charge and all the pairs of electrons surrounding it?

  2. bon

    I think you need to recall the definition of an acid (in the Bronsted-Lowry scheme). An acid is a proton donor. A base is a proton acceptor. When a acid dissociates, it forms a hydrogen ion and the conjugate base of the acid. Remember, acid and base are only relative terms. The species which loses a proton in the reaction is acting as an acid and that which gains a proton is a base.
    In the example above, the ketone is acting as an acid because it donates a proton. The hydride anion is acting a base because it accepts a proton. The resulting enolate anion is stabilised by delocalisation of the negative charge onto the oxygen. In the reverse reaction, the enolate would act as a base, accepting a proton from hydrogen (this is unlikely to happen though because the hydrogen will be liberated as a gas).

  3. DraggyWolf

    It will shift the places of the double bond and one of the hydrogen atoms, which will end up in a compound with a double bond between two of the carbon atoms.
    That makes an enol which isn't as stable as a Ketone. The enol and Ketone are in a equilibrium which causes the enol to lose an hydrogen ion which then - the enol will become an enolate.

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