Ketoacidosis Pathophysiology

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Diabetic Ketoacidosis: A Current Appraisal Of Pathophysiology And Management

This is a current appraisal of new insights into the pathophysiology and management of diabetic ketoacidosis (DKA), including laboratory work-up, monitoring of insulin, and fluid management. This article also discussed the complications of DKA and its treatment, focusing on cerebral edema (CE). The author recommends that fluid deficits be replaced at an even rate over 48 h, not to exceed 4/L/m2/24 h. Regular insulin should be started at 0.1 units/kg/h (no bolus). In general, it is recommended that bicarbonate not be administered unless correction of a pH < 6.9 is necessary. To access this article, please choose from the options below Continue reading >>

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