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Ketoacidosis Pathophysiology

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Acute Complications Of Diabetes - Diabetic Ketoacidosis

- [Voiceover] Oftentimes we think of diabetes mellitus as a chronic disease that causes serious complications over a long period of time if it's not treated properly. However, the acute complications of diabetes mellitus are often the most serious, and can be potentially even life threatening. Let's discuss one of the acute complications of diabetes, known as diabetic ketoacidosis, or DKA for short, which can occur in individuals with type 1 diabetes. Now recall that type 1 diabetes is an autoimmune disorder. And as such, there's an autoimmune destruction of the beta cells in the pancreas, which prevents the pancreas from producing and secreting insulin. Therefore, there is an absolute insulin deficiency in type 1 diabetes. But what exactly does this mean for the body? To get a better understanding, let's think about insulin requirements as a balancing act with energy needs. Now the goal here is to keep the balance in balance. As the energy requirements of the body go up, insulin is needed to take the glucose out of the blood and store it throughout the body. Normally in individuals without type 1 diabetes, the pancreas is able to produce enough insulin to keep up with any amount o Continue reading >>

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Popular Questions

  1. chele

    During my last urine sample at hospital they noted ketones in my urine. They never mentioned it, but it's got me worried. I'm seeing midwife on Friday and will do another test, but why on earth are there ketones in my urine??!!
    I ate a sandwich before my sample so it's not due to low carbs. I'm not dieting. Ok I've put no weight on, but haven't lost any either (which I admit to finding weird as I've not exactly been eating healthily)
    What could it be due to? Should I worry?

  2. vicky84

    there was leukocytes in mine on thurs and i dont know what that means either!!

  3. chele

    leukocytes is when ur body is fighting off an infection. You might not even know you have one and could be anything such as your body recoverng from a small cut even.
    Anyone else any help on the ketones?

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