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Is Ketosis Healthy Long Term

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Following A Ketogenic Diet For 5 Years, The Story Of Glucose Transporter 1 Deficiency Syndrome

T hose of us advocating an ultra-low carb™ diet struggle with the question of the long term effects of following such a prescription. The flak from high-carb (or balanced diet, as they call it) advocates originates in this basic premise: there is no long term research. Their answer to the problem: Stay the course (which we already know is NOT working). The current norm for many controlled nutritional studies is 12 weeks to a year. Clearly, this span of time in relation to the human lifespan is too short. Basing life-long recommendations on such short-lived studies could easily end up being a case of misrepresentation. As for myself, I believe it’s the strategic reintroduction of carbs at specific times that is the healthiest approach—the topics in both Carb Backloading™ and Carb Nite®. Lack of research also allows people to post opinion pieces about supposed effects of long-term ketogenic diets, effects that we don’t actually see in practice. But there’s still the elephant in the room: What really happens with long-term adherence to an ultra-low carb diet? We can look to clinical populations with certain diseases who are enrolled in studies that are generally longer in Continue reading >>

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Popular Questions

  1. Kingleonidas

    Metformin and DKA>>

    Just wondering, I have read that taking metformin without food can lead to dka, or does this usually pertain to people who eat absolutely nothing or very little all day?
    I am going to start my 850mg three times a day at about 4-5am, 9-10am, then again at the end of the day when I go to bed.
    Has anyone had a problem with metformin and dka?
    Thanks.

  2. MarkM

    no, metformin won't cause dka. its main action is to inhibit glycogenolysis. only insufficient insulin will cause dka. metformin can cause lactic acidosis, but it is not the same thing as ketoacidosis (dka).

  3. Ken S

    Studies have also shown that the risk of getting lactic acidosis with or without taking metformin is about the same. This is an extremely rare affliction that only really seems to affect patients with serious preexisting health problems. It's really not an issue to be concerned about.
    As for DKA, metformin is contradicted in cases where patients are experiencing symptoms of DKA, and therefore it may be surmised that it may worsen this condition, although it does not seem to cause it.

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