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Is Ketoacidosis Permanent

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Permanent Neonatal Diabetes Mellitus Manifesting As Diabetic Ketoacidosis.

Abstract Neonatal diabetes mellitus (NDM) is a very rare disease defined as hyperglycemia that occurs during the first month of life, requires insulin treatment, and lasts more than 2 weeks. There are 2 types of NDM: permanent neonatal diabetes mellitus (PNDM) and transient neonatal diabetes mellitus (TNDM). We report a case of PNDM in a 3-day-old female infant. This full-term neonate was born small for gestational age. Respiratory distress, poor activity, hypothermia, poor feeding, dehydration, and ketoacidosis were noted at the age of 3 days. After insulin therapy and fluid replacement, her condition became stable. Glucagon test done at the age of 26 days showed serum C-peptide level to be low for her age. During the first year of life she had catch-up growth, but insulin therapy was still required. Serum C-peptide level was undetectable at the age of 15 months. The course of this case indicates the importance of a high index of suspicion for patients with PNDM in order to correct metabolic derangement as early as possible and facilitate normal growth and development under insulin therapy. Continue reading >>

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Popular Questions

  1. Nikos Konstas

    I have been on low carb/keto for several years. It’s doable but its not easy as almost everything these days is full of carbs & low in fat. My advice would be:
    know your macros, use a keto calculator, like this one: KetoDiet Buddy - Easy Way to Calculate Your Macros on a Ketogenic Diet | The KetoDiet Blog
    Make sure your get enough electrolytes. You can make your own electrolyte drinks.
    In the long run, unless you’re treating a condition, you don’t want to go “zero carb”.
    Don’t be afraid to eat fats but know what fats to eat - not all fats are the same.
    People new to keto seem to think all you need is cheese and bacon - don’t make the same mistake - you need to have a balanced low-carb diet.

    Avoid low carb supplements/ meal replacements / ketone drinks at any cost. Know what you eat and learn to cook :)
    I run a Keto Blog with my partner - you can find guides and info on it.

    Best of luck!

  2. Peter Weintraub

    Hello - Thanks for reaching out!
    I personally have used a ketogenic diet long-term, and I have all of my clients follow one on their weight loss programs.
    In terms of tips, you want to keep your macros in this order: Fat (60–70%), Protein (20–30%) and Carbs (0–10%).
    There are no cheat days, and it will take cutting out fruits and starchy veggies for most people.
    I’ve yet to find any convincing evidence that you need to be careful following this type of nutrition long-term. So long as you’re not consuming too much protein, you’re not at risk for ketoacidosis, which many people often confuse for ketosis.
    My partner Evan and I recently did a podcast episode on this. Feel free to check it out at https://itunes.apple.com/us/podc...
    Hope this helps! If you have any further questions, feel free to email me at the address below.

    Peter Weintraub
    Founder and Permanent Weight Loss Expert at Fitness Retriever

    [email protected]

  3. Ron Hunter

    The precaution is to try to avoid cheating. The combination of refined carbohydrates and fat is something that should be avoided by all people. It’s not that fat is bad, it’s the combination.

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