Hyperglycemic Seizures

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Hyperglycemia means high blood sugar. It is the primary symptom of diabetes. Unlike its opposite, hypoglycemia, hyperglycemia is not immediately life-threatening. This doesn't mean it's not dangerous, though. For "how high is high", see blood glucose levels, and also the long-term symptoms discussion at the end of this page. Increasing physical activity can mean lowering blood sugar levels for some pets and people with this disease. It can also raise them; much depends on individual reaction and knowing how you or your pet responds. For most with diabetes, excitement or stress can cause temporary hyperglycemia. There are others who can find themselves going toward hypoglycemia because of it. Some unexpected causes of hyperglycemia are discussed in detail under regulation difficulties. Because of the hyperglycemia Cushing's disease creates, it's possible (but not frequent) to find ketones in the urine. [1] An untreated diabetic suffers primarily from lack of insulin to let nourishment into the cells, and therefore is starving to death. But hyperglycemia can kill faster than starvation; it's not unusual for one of the effects below, or diabetic ketoacidosis (DKA) brought on by the co Continue reading >>

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  1. RobinN

    Quote :

    The important new finding from Schwechter and colleagues is that hyperglycemia, itself, is proconvulsant. How can elevated glucose enhance seizure susceptibility? The answer to this crucial question regarding the mechanism of action awaits further research, as the mechanism per se is not addressed in this report. However, one clue to the answer might be gleaned from the authors's observation that hypoglycemia was associated with a higher seizure threshold. Other studies have indicated that restricting calories, thus inducing hypoglycemia, in the epilepsy-prone EL mouse also reduces seizure susceptibility (2). With any model that induces hypoglycemia, the role of ketosis must be excluded, as ketones themselves can affect seizure threshold (3). Moreover, multiple other mechanisms could explain hypoglycemia- and hyperglycemia-induced alterations of neuronal excitability. Furthermore, the effects of age on glucose balance and neuronal excitability must be delineated, as children with diabetes tend to develop seizures with hypoglycemia rather than with hyperglycemia. In addition to clarifying further the relation between hyperglycemia and seizures, Schwechter et al. highlight the link between metabolism and neuronal excitability and emphasize the need for further research on the long-term effects of hyperglycemia on various aspects of brain function.

  2. Nakamova

    I have the opposite experience -- for me, low blood sugar (hypoglycemia) is a seizure trigger, it lowers my seizure threshold....

  3. RobinN

    Yes I am doing some research on this, as the same seems to be true for my daughter as well.
    Her blood sugar is dropping before a seizure and then sometime spiking after.
    Though her last seizure when 911 was called it went down to 30. So we had a glucose tolerance test and it was at 50 on the last blood draw.
    I am reading conflicting information. Which only proves to me that they don't know much about this or why it really occurs.
    Can you tell me what you have done to try to remedy your situation. How do you manage it?
    Have you made nutritional changes?

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