How Are Ketones Excreted From The Body

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1 Ketones In Urine Summary

Ketones in urine, or ketonuria, as the name suggests, is characterized by the presence of ketones or ketone bodies in the urine. Ketones build up in the body when fat cells are burned to produce energy. This can be a dangerous condition if the amount of ketone is very high, particularly in people with diabetes who have high glucose levels. Carbohydrates, fats, and proteins are metabolized by the body for the generation of energy, which is used for various metabolic and enzymatic processes within the cells. On a priority basis, carbohydrates are always metabolized for the production of energy. This is then followed by the metabolization of fats and proteins. However, in some instances when the body starts generating high proportions of energy by metabolizing fats or fatty acids, a waste product of this activity accumulates in the body, which is called ketone bodies. This is usually associated with a lack of sugar or carbohydrates in the diet. These ketones are known to be eliminated through the kidneys. Hence, doctors usually perform urine tests to identify the presence of excessive ketones in the body. The concentration of ketone bodies in the urine under normal conditions is less Continue reading >>

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Popular Questions

  1. HopefulMDclass2020

    Which of the following are likely fates of acetone in the body?
    I. Excretion in the urine
    II. Conversion back to acetoacetate
    III. Involvement in the anabolism of amino acids
    I only (Correct answer)
    I and II only
    II and III only
    I, II, and III
    "A is correct. This question is asking us to determine from the passage the likely fate of acetone. The passage mentions that acetone has no metabolic utility. Thus choices II and III are incorrect. Acetone is simply excreted in the urine.
    B, C, D: All of these choices include either II or III, which incorrectly describle metabolic uses for acetone in the body."
    I was under the impression that ketone bodies enter circulation and can be taken up by other cells and converted back to acetyl-CoA. I will admit that the passage implied that acetone had no metabolic use, and I should have answered the question off the passage information and not my background information. But I was wondering what y'all think.

  2. HopefulMDclass2020

    This might be useful also. Showing the one way conversion of acetone. I am just a little confused because I thought ketone bodies HAD metabolic use

  3. HopefulMDclass2020

    Welp, I just did some googling and found the answer. The only two ketone bodies are beta-hydroxybutyrate and acetoacetate, while acetone is just a waste product. "The product of the decarboxylation reaction, acetone, is a volatile waste product, and is largely excreted via the lungs."
    Hopefully this can help someone in the future with a similar problem.

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