diabetestalk.net

Effect Ketone Bodies

Share on facebook

Ketone Body Metabolism

Ketone body metabolism includes ketone body synthesis (ketogenesis) and breakdown (ketolysis). When the body goes from the fed to the fasted state the liver switches from an organ of carbohydrate utilization and fatty acid synthesis to one of fatty acid oxidation and ketone body production. This metabolic switch is amplified in uncontrolled diabetes. In these states the fat-derived energy (ketone bodies) generated in the liver enter the blood stream and are used by other organs, such as the brain, heart, kidney cortex and skeletal muscle. Ketone bodies are particularly important for the brain which has no other substantial non-glucose-derived energy source. The two main ketone bodies are acetoacetate (AcAc) and 3-hydroxybutyrate (3HB) also referred to as β-hydroxybutyrate, with acetone the third, and least abundant. Ketone bodies are always present in the blood and their levels increase during fasting and prolonged exercise. After an over-night fast, ketone bodies supply 2–6% of the body's energy requirements, while they supply 30–40% of the energy needs after a 3-day fast. When they build up in the blood they spill over into the urine. The presence of elevated ketone bodies i Continue reading >>

Share on facebook

Popular Questions

  1. danielcruit

    What if I did 100g/day, or 50g/day?
    I'm trying to do this with my partner, and just due to life situation, we don't really have the ability to track religiously what we eat, and staying under 20g is not really possible, for reasons I don't want to get into now. What I'm interested in is simply whether weight loss will still occur at 100g or 50g/day, just more slowly than under 20g, or if we won't lose any weight at all.
    I'm also confused about calories- I'm really a beginner to this, but I was lead to believe that calories didn't matter, only how much carbs you ate, but I see people on this sub all the time asking "how many calories are you eating a day?" to people who say that they are having trouble losing weight on keto.
    Thanks so much for any insight, my understanding of this is really limited.

  2. anbeav

    Ketosis != weight loss
    Ketosis works for many because it makes eating at a deficit feel easier but it's not required for weight loss.
    Also most at less than 100 grams/day are transiently in ketosis.
    If you eat fewer calories than you need at 100 or 50 gram carb intake, you will lose weight. People lose weight eating at much higher carb intake. Keto is not the only way to lose weight (caveat: insulin resistance complicates this situation)
    Calories aren't all that matters, but they matter. For some they can achieve a caloric deficit eating to satiety, many others cannot and need to count calories. If you're not eating in a deficit, you will not lose weight. Calories mater.

  3. IRiseFromTheAshes

    I've never understood why carbs are limited to 0-50g/day, with emphasis of eating under 30g, if being under 100g will still keep you at some level of ketosis. I find it frustrating at times having to limit my vegetable intake of all things simply because I require a lot of calories / day (sometimes close to 4000), which means that proportionally I would have say, 40g of carbs from vegetable instead of 20g from someone eating 2000 calories.

  4. -> Continue reading
read more close

Related Articles

Popular Articles

More in ketosis