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Dose Of Sodium Bicarbonate In Metabolic Acidosis

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Sodium Bicarbonate In The Critically Ill Patient With Metabolic Acidosis

Sodium bicarbonate in the critically Ill patient with metabolic acidosis Uso de bicarbonato de sdio na acidose metablica do paciente gravemente enfermo Lactic acidosis is an acid-base imbalance frequently found in critically ill patients. It is associated with a poor prognosis. Despite the substantial body of evidence that critical levels of acidemia have several adverse effects on cell function, the use of sodium bicarbonate to treat lactic acidosis in critically ill patients remains highly controversial. This article aimed at: 1) analyzing the main differences between hyperchloremic and organic acidoses, with high anion gap; 2) comparing the risks associated with critical levels of acidemia with those associated with the use of sodium bicarbonate; 3) critically analyzing the literature evidence about the use of sodium bicarbonate for the treatment of lactic acidosis in critically ill patients, with an emphasis on randomized control trials in human beings; and 4) providing a rationale for the judicious use of sodium bicarbonate in that situation. Descriptors: lactic acidosis, diabetic ketoacidosis, sodium bicarbonate, septic shock. A acidose ltica um distrbio do equilbrio cido-ba Continue reading >>

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Popular Questions

  1. WhoAteMyPsyche

    I've been trying to find the science between how the body reacts in ketosis vs someone who just tries to keep their carbs low. I know some people can be in ketosis with 50 carbs or less, but I do not think that is the case for most people.
    When I first started losing weight I was keeping my carbs between 40-50, and lost between 80-90 lbs. doing that. I then started doing more research (I stalled for a long time) and switched to keto and keep my carbs below 20. However, I'm working on a blog post trying to explain keto and would like to be able to explain, intelligently, the difference in ketosis vs "lowish" carbs.

    Can anyone point me to good research on this? Thank you!

  2. Fiorella

    Honestly, I think the best data or research is testing your own body, as in n=1. Starting at 20 g carbs is a starter's template. From there, you may need to go lower, or get away with pushing it higher. Let's say someone comes up with a bell curve showing where people have there carbs set at. It will still be a snapshot in time, possibly skewed to men/women only, age groups, metabolic diseases, athletic/sedentary, etc. Also, some people noticed that with time, the carb level requirement changed as their bodies health modified, too.

  3. WhoAteMyPsyche

    I completely agree that everyone is different and that the carb levels can change over time. I know, at least in my experience, just because someone knows about low carb doesn't mean they know what ketosis is. When I first started I was going off a plan I had followed in the 90s (Protein Power Plan) and knew nothing about ketosis. I had heard the term "keto" thrown around by a few people but just thought it was a different way of saying the same thing - Protein Power, Atkins, etc. So I guess the key is telling people WHAT keto is and why lowering your carbs works. They can then take that info and learn for themselves what works for them.

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