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Does Ketosis Cause Kidney Stones

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Kidney Stones And The Ketogenic Diet: Risk Factors And Prevention.

Abstract A cohort study was performed of children started on the ketogenic diet for intractable epilepsy from 2000 to 2005 (n = 195). Children who developed kidney stones were compared with those without in terms of demographics, urine laboratory markers, and intervention with urine alkalinization (potassium citrate). Thirteen children (6.7%) developed kidney stones. The use of oral potassium citrate significantly decreased the prevalence of stones (3.2% vs 10.0%, P = .049) and increased the mean time on the ketogenic diet before a stone was first noted (260 vs 149 patient-months, P = .29). The prevalence of kidney stones did not correlate with younger age or use of carbonic anhydrate inhibitors (eg, topiramate or zonisamide) but trended toward higher correlation with the presence of hypercalciuria (92% vs 71%, P = .08). No child stopped the diet due to stones; in fact, the total diet duration was longer (median 26 vs 12 months, P < .001). Kidney stones continue to occur in approximately 1 in 20 children on the ketogenic diet, and no statistically significant risk factors were identified in this cohort. As oral potassium citrate was preventative, prospective studies using this medi Continue reading >>

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Popular Questions

  1. Chet

    I am genetically acidic. This causes me to get gout and/or kidney stones.
    When I tried the Atkins diet (many many years ago) I believe that I went into ketosis and suffered gout and kidney stones.
    I am concerned that the PB will cause the same thing (while losing weight) as ketosis makes one acidic and I already am.
    I hope that the addition of fruits & veggies will preclude this.
    I had a wellness M.D. suggest that I take lots of magnesium; drink the following once to twice a week (2 oz's natural apple cider vinegar, 2 oz's lemon juice, & 2 oz's natural apple cider) to make me alkaline; and to stay hydrated. Since doing this, I have not had kidney stones, but get gout/pseudo gout if I don't stay hydrated.
    Hydrated was defined as enough water to cause 2 liters of urine/day. Living in Hawaii this results in way more than 8 glasses of water per day.
    Any thoughts?

  2. Elliot

    I can't talk about gout but vegetables can promote kidney stones. The oxalate in spinach is probably responsible.
    A randomized trial of low-animal-protein or high-fiber diets for se... - PubMed - NCBI
    Randomized controlled trial of a low animal protein, high fiber die... - PubMed - NCBI

  3. Neckhammer

    You should be fine. Stay hydrated. Watch the oxylates. I dont think it has anything to do with your "acidity"....not on PB or in ketosis. Magnesium deficiency and other deficiencies along with dehydration though? Ya, probably big part of it.

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