Dka Management Uptodate

Share on facebook

Diabetic Ketoacidosis And Hyperosmolar Hyperglycemic State In Adults: Epidemiology And Pathogenesis

INTRODUCTION Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS, also called hyperosmotic hyperglycemic nonketotic state) are two of the most serious acute complications of diabetes. They each represent an extreme in the hyperglycemic spectrum. The epidemiology and the factors responsible for the metabolic abnormalities of DKA and HHS in adults will be discussed here. The clinical features, evaluation, diagnosis, and treatment of these disorders are discussed separately. (See "Diabetic ketoacidosis and hyperosmolar hyperglycemic state in adults: Clinical features, evaluation, and diagnosis" and "Diabetic ketoacidosis and hyperosmolar hyperglycemic state in adults: Treatment".) EPIDEMIOLOGY Diabetic ketoacidosis (DKA) is characteristically associated with type 1 diabetes. It also occurs in type 2 diabetes under conditions of extreme stress such as serious infection, trauma, cardiovascular or other emergencies, and, less often, as a presenting manifestation of type 2 diabetes, a disorder called ketosis-prone diabetes mellitus. (See "Syndromes of ketosis-prone diabetes mellitus".) DKA is more common in young (<65 years) patients, whereas hyperosmolar hyperglycemic s Continue reading >>

Share on facebook

Popular Questions

  1. SugarMama

    I've noticed especially in the last few days that I am sooo thirsty. My mouth and throat feel so dry. I've been drinking about 3liters of water a day. Any suggestions?

  2. Polargirl

    I noticed this too. Even wakes me up during the night. I drink a ton of water too. Looking fwd to seeing replies.

  3. Katinka

    I went through this at the end of my Whole30 for about 10 days or so. I have no idea how to fix it, other than to continue drinking lots of water, but in my experience it goes away on it's own. Hang in there!

  4. -> Continue reading
read more close

Related Articles

  • Dka Management Uptodate

    INTRODUCTION Current treatments for type 2 diabetes have centered on increasing insulin availability (either through direct insulin administration or through agents that promote insulin secretion), improving sensitivity to insulin, delaying the delivery and absorption of carbohydrate from the gastrointestinal tract, or increasing urinary glucose excretion. Sodium-glucose co-transporter 2 (SGLT2) inhibitors reduce blood glucose by increasing urina ...

    ketosis Jan 5, 2018
  • Dka Protocol Uptodate

    Approach Considerations In patients with diabetic ketoacidosis, the first principals of resuscitation apply (ie, the ABCs [airway, breathing, circulation]). [3] Outcomes are best when children are closely monitored and a changing status is promptly addressed. [39, 2] Give oxygen, although this has no effect on the respiratory drive of acidosis. Diagnose by clinical history, physical signs, and elevated blood glucose. Fluid, insulin, and electroly ...

    ketosis Jan 14, 2018
  • Infant Of Diabetic Mother Uptodate

    Jamie Haushalter, CPNP-PC Newborn Nursery Emily Freeman, CPNP-PC Newborn Nursery Purpose and Objectives Review pathophysiology of diabetes in pregnancy and implications for the newborn Apply “Up to Date†Information to practice. The learner will be able to Identify at least 3 neonatal complications associated with being an infant of a diabetic mother. Explain the pathophysiology of increased incidence of respiratory distress in the IDM ...

    diabetes Dec 30, 2017
  • Alcoholic Ketoacidosis Uptodate

    This is EM Cases Best Case Ever 58 – Euglycemic DKA with Walter Himmel, the walking encyclopedia of emergency medicine. It’s not only run of the mill DKA, starvation and alcoholic ketoacidosis that can cause a metabolic acidosis with elevated ketones. Euglycemic DKA can be caused by the newer diabetes medications sodium-glucose co-transporter 2 inhibitors like Canagliflozin; and it’s important to recognize this tricky diagnosis early and in ...

    ketosis Feb 24, 2018
  • Dka Management Flowchart

    Overview National guidelines flowchart for the management of DKA from the Joint British Diabetes Societies Inpatient Care Group. Clinical Guidelines This guideline has been approved by the Trust's Clinical Guidelines Assessment Panel as an aid to the diagnosis and management of relevant patients and clinical circumstances. Not every patient or situation fits neatly into a standard guideline scenario and the guideline must be interpreted and appli ...

    ketosis Jan 14, 2018
  • Dka Management In Pediatrics

    Pediatric DKA was identified as one of key diagnoses that we need to get better at managing in a massive national needs assessment conducted by the fine folks at TREKK – Translating Emergency Knowledge for Kids – one of EM Cases’ partners who’s mission is to improve the care of children in non-pediatric emergency departments across the country. You might be wondering – why was DKA singled out in this needs assessment? It turns out that ...

    insulin Jan 14, 2018

Popular Articles

More in ketosis